Annotation Detail for CEP78
Basic Information
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| Gene Symbol: | CEP78 ( C9orf81,FLJ12643,FLJ52093,IP63,MGC135040 ) |
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| Gene Full Name: | centrosomal protein 78kDa |
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| Band: | 9q21.2 |
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| Quick Links | Entrez ID:84131; OMIM: NA; Uniprot ID:CEP78_HUMAN; ENSEMBL ID: ENSG00000148019; HGNC ID: 25740 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| Cell Cycle, Mitotic |
| Pathway ID | Pathway Name |
|---|
| 500383 | Loss of proteins required for interphase microtubule organization from the centrosome |
| 500384 | Loss of Nlp from mitotic centrosomes |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of CEP78 mRNA | affects expression | 21346803
|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene affects the expression of CEP78 mRNA | affects expression | 21346803
|
| D000643 |
Ammonium Chloride |
Ammonium Chloride affects the expression of CEP78 mRNA | affects expression | 16483693
|
| C025299 |
polyphenols |
polyphenols results in decreased expression of CEP78 mRNA | decreases expression | 16293270
|
| D012402 |
Rotenone |
Rotenone results in increased expression of CEP78 mRNA | increases expression | 19013527
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000138 |
Acidosis |
|
Ammonium Chloride |
4.10 | 18287403 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
3.09 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
3.09 | 16705839 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
3.00 | 6135515 |
| MESH:D003110 |
Colonic Neoplasms |
|
polyphenols |
2.72 | 16293270 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
12.56 | 18551238 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
12.56 | 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
6.83 | 21346803 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
6.83 | 21346803 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
polyphenols |
6.83 | 19370779 |
| MESH:D007249 |
Inflammation |
|
polyphenols |
3.22 | 16366677 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
8.39 | 16705839 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
8.39 | 16705839 |
| MESH:D008107 |
Liver Diseases |
|
polyphenols |
2.85 | 16698588 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
2.25 | 7678174 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.74 | 2876784 2876786 6135515 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
12.21 | 18551238 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
12.21 | 18551238 7678174 |
| MESH:D009410 |
Nerve Degeneration |
|
Rotenone |
4.15 | 15790535 17356569 18619942 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
10.06 | 12819281 16049721 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
10.06 | 16049721 |
| MESH:D010300 |
Parkinson Disease |
|
Rotenone |
3.08 | 15451049 18191903 19114014 11445065 16140633 19232380 11535288 18619942 16412576 |
| MESH:D020734 |
Parkinsonian Disorders |
|
Rotenone |
4.42 | 15574749 18197244 15795934 15927086 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
6.65 | 18551238 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
6.65 | 18551238 |
| MESH:D013705 |
Temporomandibular Joint Disorders |
|
polyphenols |
5.86 | 17997062 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
5.39 | 16049721 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
5.39 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
13.86 | 10091137 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
13.86 | 10091137 |
| Pathway ID |
Pathway Name |
|---|
| REACT:152 |
Cell Cycle, Mitotic |
Related Diseases/Disorders