AutismKB 2.0

Annotation Detail for ZNF644


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Basic Information Top
Gene Symbol:ZNF644 ( BM-005,KIAA1221,MGC60165,MGC70410,Zep-2 )
Gene Full Name: zinc finger protein 644
Band: 1p22.2
Quick LinksEntrez ID:84146; OMIM: NA; Uniprot ID:ZN644_HUMAN; ENSEMBL ID: ENSG00000122482; HGNC ID: 29222
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D006710 Homocysteine Homocysteine results in decreased expression of ZNF644 mRNAdecreases expression 17326132
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ZNF644 mRNAdecreases expression 19150397
D003010 Clorgyline Clorgyline results in increased expression of ZNF644 mRNAincreases expression 19691856
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D001321 Autistic Disorder Homocysteine 3.0220468076 16297937
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0120889678
MESH:D003324 Coronary Artery Disease Homocysteine 3.8716379339
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1520426865
MESH:D017889 Exfoliation Syndrome Homocysteine 6.4416504073
MESH:D005901 Glaucoma Homocysteine 5.8216504073
MESH:D006330 Heart Defects, Congenital Homocysteine 4.2019638421
MESH:D020138 Hyperhomocysteinemia Homocysteine 5.1217369066 18234410 17292331
MESH:D008591 Meningomyelocele Homocysteine 6.1916602021
MESH:D009203 Myocardial Infarction Homocysteine 3.8617412321
MESH:D010300 Parkinson Disease Homocysteine 3.7016275827
MESH:D011471 Prostatic Neoplasms Clorgyline 4.2219691856
MESH:D012559 Schizophrenia Homocysteine 3.1416641680
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018