AutismKB 2.0

Annotation Detail for ARID5B


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Basic Information Top
Gene Symbol:ARID5B ( DESRT,FLJ21150,MRF2 )
Gene Full Name: AT rich interactive domain 5B (MRF1-like)
Band: 10q21.2
Quick LinksEntrez ID:84159; OMIM: 608538; Uniprot ID:ARI5B_HUMAN; ENSEMBL ID: ENSG00000150347; HGNC ID: 17362
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
Diastolic blood pressure
CARDIOVASCULAR
CANCER
Acute lymphoblastic leukemia (childhood)
Desease Name
Acute lymphoblastic leukemia (childhood)
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of ARID5B mRNAincreases expression 18687144
C004541 biochanin A biochanin A results in increased expression of ARID5B mRNAincreases expression 12111696
D002945 Cisplatin ARID5B protein affects the susceptibility to Cisplatinaffects response to substance 16217747
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ARID5B mRNAaffects cotreatment|increases expression 17942748
D005472 Fluorouracil ARID5B protein affects the susceptibility to Fluorouracilaffects response to substance 16217747
C106014 gedunin gedunin results in decreased expression of ARID5B mRNAdecreases expression 17010675
D007213 Indomethacin Indomethacin results in decreased expression of ARID5B mRNAdecreases expression 16984733
D010634 Phenobarbital Phenobarbital results in decreased expression of ARID5B mRNAdecreases expression 19270015
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ARID5B mRNAaffects binding|decreases expression|increases activity 19710929
D020849 Raloxifene Raloxifene affects the expression of ARID5B mRNAaffects expression 14699072
C017947 sodium arsenite sodium arsenite results in increased expression of ARID5B mRNAincreases expression 16014739
D013629 Tamoxifen Tamoxifen affects the expression of ARID5B mRNAaffects expression 14699072
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ARID5B mRNAaffects cotreatment|increases expression 17942748
C024746 tobacco tar tobacco tar results in decreased expression of ARID5B mRNAdecreases expression 19559774
C050414 tripterine tripterine results in decreased expression of ARID5B mRNAdecreases expression 17010675
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.6114745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 8.466195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.4611752688 15322242 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0017505938
MESH:D058186 Acute Kidney Injury Cisplatin 3.9915814532 17670903 12690470
MESH:D055371 Acute Lung Injury pirinixic acid 3.1518653653
MESH:D000230 Adenocarcinoma Cisplatin 10.2911798837 17638652
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 10.2914692618
MESH:D000230 Adenocarcinoma Fluorouracil 10.2917638652
MESH:D000230 Adenocarcinoma Indomethacin 10.2916537180
MESH:D000236 Adenoma Indomethacin 3.4711497255
MESH:D018248 Adenoma, Liver Cell Phenobarbital 17.6017620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 17.6016434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 17.6016835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.7615276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.9616712894 17306315
MESH:D000419 Albuminuria Raloxifene 4.6317308373 17451421
MESH:D016301 Alveolar Bone Loss Indomethacin 5.4317225004
MESH:D000544 Alzheimer Disease Indomethacin 4.4915579461 17627676
MESH:D000544 Alzheimer Disease Raloxifene 4.4915800139
MESH:D000740 Anemia Fluorouracil 8.7715504547 17963324 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.7711748828
MESH:D001014 Aortic Aneurysm Indomethacin 4.8810231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.9110388637
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5111256880
MESH:D018771 Arthralgia Indomethacin 5.232160914
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6815885639
MESH:D001172 Arthritis, Rheumatoid Indomethacin 2.8311248219
MESH:D001477 Bartter Syndrome Indomethacin 5.0210684365
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.8619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.8612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7815746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 4.9514601052
MESH:D001929 Brain Edema Indomethacin 5.0911481608
MESH:D001930 Brain Injuries Raloxifene 4.5216580743
MESH:D002545 Brain Ischemia Indomethacin 4.4712524144
MESH:D001943 Breast Neoplasms Cisplatin 2.9819526202 18382427
MESH:D001943 Breast Neoplasms Fluorouracil 2.9819217205 16557594 16595493 16110121 15136595 18357371 18608205
MESH:D001943 Breast Neoplasms Indomethacin 2.9817401462
MESH:D001943 Breast Neoplasms Raloxifene 2.9817242785 15758505 17440819 17049068 15775269 17893378 17595753 17952589 16912660 15572757 16837676 17261762
MESH:D001943 Breast Neoplasms Tamoxifen 2.9819142967 19288272 16273361 17893378 19059307 17440819 18984771 20859285 19244106 19487384 19066611 15565566 19289846 18815881 18855134 17261762 18997820 19189212 19103187 19200415 18821012 19189210 20005174 17049068 19410462 20544844 16818667 20390343 20065188 19221464 21138602 21152245 18351453 19011961 16202921 19084267 18425577 11161223 16873071 20135344 17242785 15668708 19115204 19155303 18629630
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.9820435547
MESH:D002056 Burns Indomethacin 4.7510459503
MESH:D002100 Cachexia Indomethacin 5.0615625704 16537180 15141370 11239499
MESH:D002276 Carcinoid Tumor Fluorouracil 4.7316051944
MESH:D002277 Carcinoma Fluorouracil 8.2617121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 8.2616835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.5519066611
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 11.4717982673
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 11.4717088986 17045692 16799960 18930000 17971768 16332177
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 11.4716391822
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 11.4720007298 6705139 1701930 20935162 17173139
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 11.4717306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.4716924424
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 4.7811053908
MESH:D018276 Carcinoma, Medullary Indomethacin 5.4014736730 18791128 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 3.0416685392 12023789
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 6.7918695887
MESH:D002292 Carcinoma, Renal Cell Indomethacin 6.7917341418
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 10.9318337622 6189445 17066447
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 10.9318986760 17066447 16280240 16757204
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 10.9312636206 15482327
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 10.9318572023
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 9.5917572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 9.5917572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3818850075 16120746 18670907
MESH:D002318 Cardiovascular Diseases Raloxifene 3.4615775269
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 7.2419524636 20056578
MESH:D002471 Cell Transformation, Neoplastic tobacco tar 7.2419559774
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.294080065
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1916835633
MESH:D002764 Cholecystitis Indomethacin 5.2311181007
MESH:D002779 Cholestasis Ethinyl Estradiol 7.8117110522 11677210 17333356 16919318 15861022 16105132 17681005
MESH:D002779 Cholestasis pirinixic acid 7.8119176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1116354765 8697196 15668235 12621046 15340226
MESH:D003072 Cognition Disorders Raloxifene 4.6615800139
MESH:D003110 Colonic Neoplasms Fluorouracil 3.9817169374 16510598 17172411 15001691 17018589 18772588 17287894 16340194 17016597 17725105
MESH:D003110 Colonic Neoplasms Indomethacin 3.9815637740 15936596 11260862 15786552 15625704 15963497
MESH:D015179 Colorectal Neoplasms Cisplatin 3.5815273666
MESH:D015179 Colorectal Neoplasms Fluorouracil 3.5816391804 18509181 17094418 17401013 14970324 18288408 17255274 17594712 18448328 18383874 17695437 15289873 20501625 18949393 18802399 15148649 16524972 16282729 17016601 16331619 17454858 16303861
MESH:D015179 Colorectal Neoplasms Indomethacin 3.5812606626 18059344 17054584 11197048
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0814669216 17141729
MESH:D018352 Coronavirus Infections Indomethacin 5.7817302372
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2520055451 10048152 15322242
MESH:D007644 Darier Disease Fluorouracil 4.8416733453
MESH:D003711 Demyelinating Diseases Tamoxifen 4.4019031437
MESH:D003865 Depressive Disorder, Major Raloxifene 4.1917474826
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4418249437
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6717107852
MESH:D003928 Diabetic Nephropathies Raloxifene 9.1217308373 17451421 15920148
MESH:D003928 Diabetic Nephropathies Tamoxifen 9.1219279558
MESH:D003967 Diarrhea Indomethacin 3.837907874 7237001
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 1.5420420201
MESH:D004362 Drug Toxicity Cisplatin 8.2512649298 19839026 12231392 15033597
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 8.2511462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 5.2018446180 17190690 16133044 12774134 16326151 18043480
MESH:D004381 Duodenal Ulcer Indomethacin 4.1717351913 17045617 11991626 17202747 10671773 11595431 16699067 11535926 11595415 17329845 17151854
MESH:D004421 Dystonia Phenobarbital 4.041851702
MESH:D004487 Edema Indomethacin 16.7119703484 8273558 7907874 10653021 16100529 7990266 8985016
MESH:D004487 Edema pirinixic acid 16.7112083418
MESH:D004487 Edema Raloxifene 16.7115860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 16.7111000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9618230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 15.5812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 15.5815845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 15.5819031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.0620544844 16202921 19155303 17893378
MESH:D004715 Endometriosis Indomethacin 9.1615652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 9.169294722 10568697
MESH:D019446 Endotoxemia Indomethacin 4.5518509659
MESH:D004751 Enteritis Indomethacin 4.8110567023 16328016 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 5.0217980183
MESH:D004802 Eosinophilia Indomethacin 4.0911298111
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.153659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.933922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.9020417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.576401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.297750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.073659116
MESH:D004938 Esophageal Neoplasms Cisplatin 7.4716481741 15173087 17638652 15464296 16785472
MESH:D004938 Esophageal Neoplasms Fluorouracil 7.4715173087 16337965 16785472 17638652 16481741
MESH:D004938 Esophageal Neoplasms Indomethacin 7.4711005569
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0311564622
MESH:D005234 Fatty Liver Ethinyl Estradiol 19.0315345470
MESH:D005234 Fatty Liver pirinixic acid 19.0320131406 19236843
MESH:D005234 Fatty Liver Raloxifene 19.0317473493
MESH:D005234 Fatty Liver Tamoxifen 19.0319224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2516709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5011858732
MESH:D005334 Fever Indomethacin 4.1411852909 17627676 10431976
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.5814745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.2319069698
MESH:D005354 Fibrosarcoma Indomethacin 4.9410962813
MESH:D005355 Fibrosis Indomethacin 8.9617994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.9620067830
MESH:D005499 Folliculitis Indomethacin 5.2311298111
MESH:D005756 Gastritis Indomethacin 4.8115046732
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.7316452187
MESH:D005909 Glioblastoma biochanin A 7.9216598420
MESH:D005909 Glioblastoma Indomethacin 7.9212870263
MESH:D005910 Glioma Fluorouracil 6.2816145905
MESH:D005910 Glioma Indomethacin 6.2818371953 16487511
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 4.3111849393
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6610696789
MESH:D006073 Gout Indomethacin 5.4011248219
MESH:D006258 Head and Neck Neoplasms Cisplatin 13.1915464296 15102660
MESH:D006258 Head and Neck Neoplasms Fluorouracil 13.1915162350 18337622 15102660
MESH:D006258 Head and Neck Neoplasms Indomethacin 13.1915482327
MESH:D034381 Hearing Loss Cisplatin 4.3219898482
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.4415464296
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3410048152 11294989
MESH:D006331 Heart Diseases Raloxifene 3.5511110106
MESH:D006333 Heart Failure pirinixic acid 2.5520558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3611000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.6015633222
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.7215135802
MESH:D006529 Hepatomegaly Phenobarbital 14.6416109766
MESH:D006529 Hepatomegaly pirinixic acid 14.6418467677 19176532 19772884 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 14.6415340226 16120746 12621046
MESH:D006689 Hodgkin Disease Cisplatin 7.6316170182 16200630
MESH:D006689 Hodgkin Disease sodium arsenite 7.6312676792
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.1116354765 18606429 16959395 15340226 8697196
MESH:D006930 Hyperalgesia Indomethacin 3.7912727271
MESH:D034321 Hyperamylasemia Indomethacin 5.7817883296
MESH:D006940 Hyperemia Indomethacin 5.0612524144
MESH:D006943 Hyperglycemia pirinixic acid 3.2120558911
MESH:D006949 Hyperlipidemias Indomethacin 4.1917546600
MESH:D006973 Hypertension Raloxifene 5.2615787275 17577099
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.2618850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8516945680 16569931
MESH:D007077 Ileal Diseases Indomethacin 5.0918306037 10574470
MESH:D007079 Ileitis Indomethacin 5.4010651667 10647630 16133968
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.4316133044
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.7017937319
MESH:D007248 Infertility, Male sodium arsenite 6.7012646999 15346721
MESH:D007249 Inflammation Indomethacin 8.4312568917 7812673 3291741
MESH:D007249 Inflammation Tamoxifen 8.4319457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 8.4312878042 12200463
MESH:D007333 Insulin Resistance pirinixic acid 2.6516306350
MESH:D007410 Intestinal Diseases Indomethacin 4.3715610444 11713966 18236018 15831440 10210152 17329856 11855677 17994277 11686837
MESH:D019586 Intracranial Hypertension Indomethacin 5.4315241188
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3616580747
MESH:D007579 Jejunal Diseases Indomethacin 5.0916133968 18306037 10574470
MESH:D007673 Kidney Cortex Necrosis Cisplatin 5.2015464296
MESH:D007674 Kidney Diseases Cisplatin 10.3612231392 12649298 18289764 19839026 15190930
MESH:D007674 Kidney Diseases Indomethacin 10.3617190690
MESH:D007674 Kidney Diseases sodium arsenite 10.3620008137
MESH:D007680 Kidney Neoplasms Fluorouracil 7.5916985049
MESH:D007680 Kidney Neoplasms Tamoxifen 7.5918625569
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.8611231351
MESH:D007889 Leiomyoma Raloxifene 4.5316973256
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.9310320625 12228301 11703811
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.9416572323 15631656 10785260
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 2.6418360721
MESH:D007964 Leukocytosis Indomethacin 5.4316537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.7817980183
MESH:D008064 Lipidoses Tamoxifen 3.1717567588 15342952
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.7811479899
MESH:D008103 Liver Cirrhosis Phenobarbital 2.9121047994
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 4.9818194892
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.9815474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.9818564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.9812878042
MESH:D008107 Liver Diseases Phenobarbital 2.1819363144
MESH:D008113 Liver Neoplasms Fluorouracil 18.1318383874 15113037 17045692 16603448
MESH:D008113 Liver Neoplasms Phenobarbital 18.1319812893 19482888 15975961 21047994 19073162 8742319
MESH:D008113 Liver Neoplasms pirinixic acid 18.1316377806 15890375 20007298
MESH:D008113 Liver Neoplasms sodium arsenite 18.1315276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 18.1316684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 18.1316984957
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 5.852563599 1399818 6150874 18308698 17172636
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 5.8512151625
MESH:D008171 Lung Diseases sodium arsenite 3.1919095001
MESH:D055370 Lung Injury Asbestos, Crocidolite 4.0617365036
MESH:D008175 Lung Neoplasms Cisplatin 8.6111798837 6189445 17225452
MESH:D008175 Lung Neoplasms Fluorouracil 8.6115246190
MESH:D008175 Lung Neoplasms Indomethacin 8.6116537180 11497255 11053908
MESH:D008175 Lung Neoplasms sodium arsenite 8.6115276417 19931552 17077188 16712894 17306315
MESH:D008175 Lung Neoplasms Tamoxifen 8.6118625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.6119555203 11884234
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.8415086387
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.8119428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.6414580682 19196722 11731420 16827153 19196723
MESH:D020149 Manganese Poisoning Tamoxifen 4.6119453300
MESH:D008545 Melanoma Cisplatin 5.1918176117 11135225 16809738 18332650 18505091 12393984 15577323 17761969 16248763 12883367 17023156 12374674 16432458
MESH:D008545 Melanoma sodium arsenite 5.1919082730 16487513
MESH:D008545 Melanoma Tamoxifen 5.1919393235 12393984
MESH:D018328 Melanoma, Amelanotic Cisplatin 11.6815990972
MESH:D018328 Melanoma, Amelanotic Tamoxifen 11.6815990972
MESH:D008654 Mesothelioma Asbestos, Crocidolite 6.5418303189 16966607 16166281
MESH:D008654 Mesothelioma Cisplatin 6.5417638057
MESH:D008881 Migraine Disorders Indomethacin 3.6911903285
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.6215863610
MESH:D009062 Mouth Neoplasms Fluorouracil 8.8918986760 16757204
MESH:D009062 Mouth Neoplasms Indomethacin 8.8912636206
MESH:D009101 Multiple Myeloma Raloxifene 3.4616497877
MESH:D009135 Muscular Diseases pirinixic acid 3.5516239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.1519151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0412213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.9716411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.5317484760
MESH:D009232 Myxoma Raloxifene 5.6216343187
MESH:D009362 Neoplasm Metastasis Indomethacin 5.9911239499 16537180 11053908
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.9919393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5219410462
MESH:D009369 Neoplasms Cisplatin 12.0116773208
MESH:D009369 Neoplasms Fluorouracil 12.0116928823 18600527 18239605
MESH:D009369 Neoplasms pirinixic acid 12.0117405874
MESH:D009369 Neoplasms sodium arsenite 12.0111559025
MESH:D009374 Neoplasms, Experimental Indomethacin 9.4215625704 10663608
MESH:D009374 Neoplasms, Experimental sodium arsenite 9.4220056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.0619196722 19189210 19200415
MESH:D009395 Nephritis, Interstitial Cisplatin 4.5515464296
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.2514600291
MESH:D009436 Neural Tube Defects sodium arsenite 3.1612854658
MESH:D009447 Neuroblastoma Cisplatin 3.468761367
MESH:D019636 Neurodegenerative Diseases Indomethacin 3.9612349958
MESH:D017599 Neuroectodermal Tumors Cisplatin 4.758761367
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.4516436463
MESH:D009765 Obesity pirinixic acid 1.8220558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 5.236374098
MESH:D010003 Osteoarthritis Indomethacin 3.687009135
MESH:D010018 Osteomalacia Phenobarbital 4.4117016548
MESH:D010024 Osteoporosis Raloxifene 3.4119059307 17882678 15775268
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.2617823083 15758505 15579764 17893378
MESH:D010051 Ovarian Neoplasms Cisplatin 5.1119769630 17225452 15464296 6897625
MESH:D010051 Ovarian Neoplasms sodium arsenite 5.1115276417 17306315
MESH:D010146 Pain Indomethacin 3.483291741 17440234 13679232 17627676
MESH:D010149 Pain, Postoperative Indomethacin 4.7412538197 18702446
MESH:D010190 Pancreatic Neoplasms Cisplatin 8.7719003803
MESH:D010190 Pancreatic Neoplasms Fluorouracil 8.7719003803 15113037 16929163 16500647
MESH:D010190 Pancreatic Neoplasms Phenobarbital 8.7716965848
MESH:D010195 Pancreatitis Indomethacin 3.9515028970 17883296
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7211578682
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.7816537180
MESH:D020734 Parkinsonian Disorders Indomethacin 4.1412349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.7811903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3112520081
MESH:D010437 Peptic Ulcer Indomethacin 5.2011148446
MESH:D010518 Periodontitis Indomethacin 4.9817225004
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 4.3415464296
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.9310923243
MESH:D010997 Pleural Neoplasms Cisplatin 5.4117638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5918163543
MESH:D011230 Precancerous Conditions Phenobarbital 3.652563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma marker/mechanism 19684604 19684603
MESH:D047928 Premature Birth Indomethacin 5.1717000239
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2411118676 11896295 11222880 11399792
MESH:D011471 Prostatic Neoplasms biochanin A 1.8912111696
MESH:D011471 Prostatic Neoplasms Fluorouracil 1.8918626508 19082440
MESH:D011471 Prostatic Neoplasms Raloxifene 1.8916536755 15731164 16220300
MESH:D011471 Prostatic Neoplasms sodium arsenite 1.8916039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.8915067354
MESH:D011507 Proteinuria Indomethacin 4.1911849393
MESH:D011537 Pruritus Ethinyl Estradiol 3.3615861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 4.5612752131
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 3.0415814490 17975199 17322281 17365031
MESH:D011693 Purpura Raloxifene 5.6215770314
MESH:D012004 Rectal Neoplasms Fluorouracil 4.0416160472 18286688 18722050 15538739
MESH:D051437 Renal Insufficiency Cisplatin 4.4515464296
MESH:D015427 Reperfusion Injury pirinixic acid 2.4019058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8718990726
MESH:D012512 Sarcoma, Ewing's Cisplatin 4.4614601052
MESH:D012640 Seizures Phenobarbital 2.7116876388 3137016 4039156 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 4.876407741
MESH:D012878 Skin Neoplasms sodium arsenite 5.6319524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.6316192470
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 5.4115464296
MESH:D013088 Spermatocele Ethinyl Estradiol 11.7716709447
MESH:D013088 Spermatocele Tamoxifen 11.7716709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.0919457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.8212854658
MESH:D013272 Stomach Diseases Indomethacin 4.4718209964 17207306 10192188 15472012 16280098 10215738 18545984 10486359 17638125 17160473 16184426 15038085 16113693
MESH:D013274 Stomach Neoplasms Cisplatin 3.5518396642 15958060 17522103
MESH:D013274 Stomach Neoplasms Fluorouracil 3.5517172411 17498489 19084572 18567086 17522103 16951190 16424979 19015929 15786421 18396642
MESH:D013274 Stomach Neoplasms Indomethacin 3.5515609394
MESH:D013276 Stomach Ulcer Indomethacin 3.6117918041 15255614 17657623 10750652 17895592 12077510 16934674 15138204 16169175 18237397 16631530 16397915 11906479 18431645 17977527 17627676 18193104 10878458 10423059 18543354 1323529 15104355 11595431 16150113 11595415 12500499 18087811 11523592 11729361 16755016 18299717 17135157 18209962 16252198 18726076 11145282 12498302 17654042 18181030 12787963 14567935 12467913
MESH:D020521 Stroke Raloxifene 3.8416837676
MESH:D013736 Testicular Neoplasms Cisplatin 4.6615464296 17225452
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9612697716
MESH:D013964 Thyroid Neoplasms Indomethacin 7.4711352223 18791128 14736730
MESH:D013964 Thyroid Neoplasms Phenobarbital 7.471399818
MESH:D013978 Tibial Fractures Raloxifene 5.2719048282
MESH:D014062 Tongue Neoplasms Fluorouracil 4.0216280240
MESH:D014456 Ulcer Indomethacin 4.9417380554 10574470
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 12.0717225452 12973940 15464296
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 12.0717572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 12.0716712894 17306315 11723127 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 12.0717572228 8653321 16712894
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 16.1016803524
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 16.1016803524
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 16.1011813266
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3314692618
MESH:D014625 Vaginal Neoplasms Cisplatin 4.6515577323
MESH:D014652 Vascular Diseases sodium arsenite 4.4717056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6612125929
MESH:D054556 Venous Thromboembolism Raloxifene 5.2716837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5714671159 15869587
MESH:D014839 Vomiting Cisplatin 11.7411897121
MESH:D014839 Vomiting Indomethacin 11.7411897121
MESH:D014846 Vulvar Neoplasms Raloxifene 5.6216343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3115886252
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA134943193
    • No data
    Releated disease ID Related disease Name
    PA446166Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Releated drug ID Related drug Name
    PA450428methotrexate
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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