AutismKB 2.0

Annotation Detail for WDR24


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Basic Information Top
Gene Symbol:WDR24 ( C16orf21,DKFZp434F054,JFP7 )
Gene Full Name: WD repeat domain 24
Band: 16p13.3
Quick LinksEntrez ID:84219; OMIM: NA; Uniprot ID:WDR24_HUMAN; ENSEMBL ID: ENSG00000127580; HGNC ID: 20852
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of WDR24 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of WDR24 mRNAaffects expression 21346803
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of WDR24 mRNAdecreases expression 20106945
D014303 Trinitrotoluene Trinitrotoluene affects the expression of WDR24 mRNAaffects expression 21346803
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Trinitrotoluene 4.827525203
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0620464547 20127859
MESH:D000236 Adenoma Benzo(a)pyrene 2.866695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.6419183758
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9917474063 20146248
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 3.1016705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 3.1016705839
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1320419170
MESH:D002386 Cataract Trinitrotoluene 4.0815817613 14694615
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.036135515
MESH:D000013 Congenital Abnormalities Trinitrotoluene 4.7715095906
MESH:D003490 Cyanosis 2,4-dinitrotoluene 22.3618551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 22.3618551238
MESH:D003490 Cyanosis Trinitrotoluene 22.3618551238
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 6.9018551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 6.9018551238 21346803
MESH:D056486 Drug-Induced Liver Injury Trinitrotoluene 6.9021346803 18551238
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0816530937
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8320471113
MESH:D006529 Hepatomegaly Trinitrotoluene 4.7915817613
MESH:D007248 Infertility, Male Trinitrotoluene 3.9212150543
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 8.5316705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 8.5316705839
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 4.897678174
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.8921137059 20195826
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.776135515 2876786 2876784
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5718816296 20464547 20135361 17053015 18569708 18520028 6695378 20064080 20869020
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.5016381670
MESH:D009336 Necrosis 2,4-dinitrotoluene 21.8518551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 21.8518551238 7678174
MESH:D009336 Necrosis Trinitrotoluene 21.8518551238
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3311141357
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 17.5912819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 17.5916049721
MESH:D009784 Occupational Diseases Trinitrotoluene 17.5917852074 12819281 14694615
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9117292933
MESH:D012640 Seizures 2,4-dinitrotoluene 11.4718551238
MESH:D012640 Seizures 2,6-dinitrotoluene 11.4718551238
MESH:D012640 Seizures Trinitrotoluene 11.4718551238
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5210029692 19755658
MESH:D013163 Splenomegaly Trinitrotoluene 5.7615817613
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.5620155912 2093021
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 9.0116049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 9.0116049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 9.0117053015
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 14.1910091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 14.1910091137
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018