AutismKB 2.0

Annotation Detail for BBOX1


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Basic Information Top
Gene Symbol:BBOX1 ( BBH,BBOX,G-BBH,gamma-BBH )
Gene Full Name: butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
Band: 11p14.2
Quick LinksEntrez ID:8424; OMIM: 603312; Uniprot ID:BODG_HUMAN; ENSEMBL ID: ENSG00000129151; HGNC ID: 964
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-6100L-carnitine biosynthesis
Pathway IDPathway Name
hsa00310Lysine degradation
Pathway IDPathway Name
Metabolism of amino acids and derivatives
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of BBOX1 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of BBOX1 mRNAaffects expression 21346803
C050147 3-(2,2,2-trimethylhydrazine)propionate 3-(2,2,2-trimethylhydrazine)propionate results in decreased activity of BBOX1 proteindecreases activity 12439634
C026137 3-hydroxyacetanilide 3-hydroxyacetanilide results in decreased expression of BBOX1 mRNAdecreases expression 18544908
D000082 Acetaminophen Acetaminophen affects the expression of BBOX1 mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in decreased expression of BBOX1 mRNAdecreases expression 18544908
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of BBOX1 proteinaffects expression 20106945
D000638 Amiodarone Amiodarone results in increased expression of BBOX1 mRNAincreases expression 19774075
D000643 Ammonium Chloride Ammonium Chloride affects the expression of BBOX1 mRNAaffects expression 16483693
C006780 bisphenol A bisphenol A affects the expression of BBOX1 mRNAaffects expression 20170705
C030123 coumarin coumarin results in decreased expression of BBOX1 mRNAdecreases expression 18480146
D003513 Cycloheximide Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of BBOX1 mRNA]decreases expression|decreases reaction 11007951
D016572 Cyclosporine Cyclosporine results in decreased expression of BBOX1 mRNAdecreases expression 20106945
D004041 Dietary Fats Dietary Fats results in increased expression of BBOX1 mRNAincreases expression 18457598
D004958 Estradiol Estradiol results in decreased expression of BBOX1 mRNAdecreases expression 20106945
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of BBOX1 mRNAaffects expression 20170705
C006253 pirinixic acid pirinixic acid results in increased expression of BBOX1 mRNAincreases expression 18301758
D013749 Tetrachlorodibenzodioxin Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of BBOX1 mRNA]decreases expression|decreases reaction 11007951
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of BBOX1 mRNAdecreases expression 11007951
D014212 Tretinoin Tretinoin results in increased expression of BBOX1 mRNAincreases expression 16249480
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.8115322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.5218287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9117505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.0818653653
MESH:D000230 Adenocarcinoma Estradiol 4.1811473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.1814692618
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.7816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.7816835633
MESH:D000505 Alopecia Tretinoin 3.5815955085
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9111748828
MESH:D000799 Angioedema Acetaminophen 3.8110982225
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.7618057881 18218290 20041841
MESH:D001161 Arteriosclerosis Dietary Fats 9.7815238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.7811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.1115885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.1116412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2516292516
MESH:D001249 Asthma Tretinoin 2.3316456186
MESH:D001281 Atrial Fibrillation Amiodarone 3.8719698954 18651412
MESH:D001321 Autistic Disorder Acetaminophen 1.4218445737
MESH:D001471 Barrett Esophagus Tretinoin 4.3616935849
MESH:D001778 Blood Coagulation Disorders Amiodarone 21.6319483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 21.6319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 21.6312125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 21.6316206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7315746008
MESH:D001862 Bone Resorption bisphenol A 3.8211985600
MESH:D001943 Breast Neoplasms bisphenol A 2.3117123778
MESH:D001943 Breast Neoplasms Dietary Fats 2.3120435547
MESH:D001943 Breast Neoplasms Estradiol 2.3118497071 12948864 19861407 17289903 17018787 16675129 17261762 14630087
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.3120435547
MESH:D001943 Breast Neoplasms Tretinoin 2.3116443354 16873071 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.5516813970
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.4316111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7616835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.1316168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 11.3016705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 11.3016705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.303084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 11.3012907637 12619106 21507988
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.3016924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 11.301917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.9517123778
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 2.2816096774 16051514
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3418850075 18670907 16120746
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.8815710769 19225199
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.0518974383
MESH:D002386 Cataract Acetaminophen 7.1410977129
MESH:D002386 Cataract Tretinoin 7.1417460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 10.976135515
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.9712371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 10.9718566989
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.5516129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1216835633
MESH:D002779 Cholestasis Cyclosporine 13.1519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.1516919318 15861022 17681005 11677210 16105132 17333356 17110522
MESH:D002779 Cholestasis pirinixic acid 13.1519176532
MESH:D002822 Choriocarcinoma Tretinoin 5.1316461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.7015668235 15340226 12621046 8697196 16354765
MESH:D002972 Cleft Palate Tretinoin 5.709407595
MESH:D003092 Colitis Tretinoin 3.6617035595
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0217141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4320055451 15322242 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.4317551590 9664655 16925845 14991402 10589399 8800419 9125849 9142499 9211117 9224671
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.7618551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.7618551238
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4018249437
MESH:D003924 Diabetes Mellitus, Type 2 coumarin 4.5519647726
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.5517107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.3719279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 11.8721346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 11.8721346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.8711287661 15968718 12540782 19085960 14550746 10915739 11739529 16081117 17906064 11461765 12153990 19416960 18713872 16109766 11743745 14725611 18071297 16781746 12705907 19739265 14986274 16177239 11529661 16485898 2444490 19420014 16227642 11834606 11421492 17562736 19164858 12594235 10663392 19923254 10774834 12392966 15619225 12958197 17522070 16393943 19370779
MESH:D056486 Drug-Induced Liver Injury Amiodarone 11.8718218290 15265979
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.8720420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7311462148
MESH:D050171 Dyslipidemias Dietary Fats 3.4218367378
MESH:D004487 Edema pirinixic acid 6.4012083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.4011000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.8518230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 11.8518230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.1512538720
MESH:D016889 Endometrial Neoplasms Estradiol 7.3219148513 18566989 11473722
MESH:D016889 Endometrial Neoplasms Tretinoin 7.3216569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.989294722 10568697
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.7211564622
MESH:D005124 Eye Abnormalities Tretinoin 8.7216938888 9664655
MESH:D005234 Fatty Liver Amiodarone 24.2214986274
MESH:D005234 Fatty Liver Cyclosporine 24.2219224547
MESH:D005234 Fatty Liver Dietary Fats 24.2219551842 19004024 17967931 18296743
MESH:D005234 Fatty Liver Ethinyl Estradiol 24.2215345470
MESH:D005234 Fatty Liver pirinixic acid 24.2219236843 20131406
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4211858732
MESH:D005355 Fibrosis Cyclosporine 20.8312639820 12168785
MESH:D005355 Fibrosis Dietary Fats 20.8318296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 20.8320067830
MESH:D005355 Fibrosis Tretinoin 20.8317994277
MESH:D005756 Gastritis Acetaminophen 3.6516983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.188708960
MESH:D005909 Glioblastoma Tretinoin 2.9817312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5710696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.1516096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.1316084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.4610048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 6.469664655 14991402
MESH:D006333 Heart Failure 3-(2,2,2-trimethylhydrazine)propionate 7.9012439634
MESH:D006333 Heart Failure pirinixic acid 7.9020558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3915720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2911000095
MESH:D006529 Hepatomegaly Amiodarone 14.1915265979
MESH:D006529 Hepatomegaly pirinixic acid 14.1919772884 16221962 18467677 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 14.1916120746 15340226 12621046
MESH:D006558 Herpes Genitalis Estradiol 5.0015709030
MESH:D019584 Hot Flashes Estradiol 3.7217088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0215340226 16354765 8697196 16959395 18606429
MESH:D006930 Hyperalgesia Acetaminophen 7.5016870215
MESH:D006930 Hyperalgesia Tretinoin 7.5016870215
MESH:D006937 Hypercholesterolemia Amiodarone 9.039751232 8137927
MESH:D006937 Hypercholesterolemia Dietary Fats 9.0321332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.5316778211
MESH:D006943 Hyperglycemia pirinixic acid 3.1420558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.5721332399
MESH:D006973 Hypertension Cyclosporine 4.8910903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.8918670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7716945680 16569931
MESH:D007037 Hypothyroidism Amiodarone 4.4718020914 17991464
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4617937319
MESH:D007249 Inflammation Dietary Fats 4.8420412841
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.8412200463 12878042
MESH:D007333 Insulin Resistance bisphenol A 17.4016393666
MESH:D007333 Insulin Resistance Dietary Fats 17.4011836018 18457598
MESH:D007333 Insulin Resistance Estradiol 17.4016627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 17.4016306350
MESH:D007410 Intestinal Diseases Tretinoin 3.7317994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.8016580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.8015992940 17551590
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.4115604871
MESH:D007674 Kidney Diseases Acetaminophen 9.8312587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 9.838314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 9.8315618244
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 17.4416705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 17.4416705839
MESH:D007680 Kidney Neoplasms Cyclosporine 17.4412371664
MESH:D007680 Kidney Neoplasms Estradiol 17.4415610895
MESH:D007938 Leukemia Tretinoin 2.7517143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.6616482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0719850784 17596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.1217361223 16140955 17339181 16331271 19075265 17217047 16891316 17712046 16788101 17368321 17107899 9834237 19035177 16766008 19642359 15748426 16935935 17506722 17301526 17649720 19225113 19029980 12679006 16823087 17294898
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.279224671
MESH:D008064 Lipidoses Amiodarone 3.4817567588 15342952
MESH:D008103 Liver Cirrhosis Dietary Fats 2.8518296743
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 4.8814659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.8815474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.8812878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 4.8816248980 18397230
MESH:D008107 Liver Diseases Acetaminophen 1.6219014921 16611625 12969438 19784758 19460945 12587719 16610002 11587558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2017185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 10.547678174
MESH:D008113 Liver Neoplasms Aflatoxin B1 10.549163691 15890375 2125692 18177683
MESH:D008113 Liver Neoplasms pirinixic acid 10.5416377806 15890375 20007298
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 10.5416984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 9.646135515 2876786 2876784
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 9.648603461
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.6412151625
MESH:D008133 Long QT Syndrome Amiodarone 3.5411989578 15350150 17391786
MESH:D008171 Lung Diseases Amiodarone 3.3412587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 4.4518516814
MESH:D008175 Lung Neoplasms Aflatoxin B1 2.2814755239
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.2811884234 19555203
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.5311807958 17203775 11408345 16891317
MESH:D020149 Manganese Poisoning Estradiol 4.4519453300
MESH:D008527 Medulloblastoma Tretinoin 2.7717453147
MESH:D008545 Melanoma Tretinoin 1.9416752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5319513568
MESH:D008591 Meningomyelocele Tretinoin 4.3916940565
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7616801185
MESH:D009135 Muscular Diseases pirinixic acid 3.4716239165
MESH:D009181 Mycoses Amiodarone 4.8717974566 12754197
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.0517596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.1219151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.1316810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.1316411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 10.2318551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 10.237678174 18551238
MESH:D009369 Neoplasms pirinixic acid 4.8417405874
MESH:D009369 Neoplasms Tretinoin 4.8416594593 16946489
MESH:D009389 Neovascularization, Pathologic Estradiol 3.7017289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.4117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2418481113 19348381
MESH:D009421 Nervous System Malformations bisphenol A 23.1116427766 11399458
MESH:D009421 Nervous System Malformations Estradiol 23.1111399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 23.1114600291
MESH:D009421 Nervous System Malformations Tretinoin 23.119125849
MESH:D009436 Neural Tube Defects Tretinoin 3.029142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.8318514411
MESH:D009765 Obesity Dietary Fats 4.4020518802 21332399 18457598 20132043 16723640 17217161 18674790 11836018 19632207
MESH:D009765 Obesity pirinixic acid 4.4020558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 8.7516049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.7516049721
MESH:D010049 Ovarian Diseases bisphenol A 4.9511985600
MESH:D010051 Ovarian Neoplasms Estradiol 4.7619401270
MESH:D010051 Ovarian Neoplasms Tretinoin 4.7616936753
MESH:D010146 Pain Acetaminophen 6.4616870215
MESH:D010146 Pain Tretinoin 6.4616870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.4515976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6511578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2212520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5218163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.1812371664
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 9.3910548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.3911118676 11399792 11896295 11222880
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 10.4220887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 10.4220887781
MESH:D011471 Prostatic Neoplasms bisphenol A 3.2816740699
MESH:D011471 Prostatic Neoplasms Estradiol 3.2816740699
MESH:D011507 Proteinuria Tretinoin 3.5616636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.2815861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.2116882103
MESH:D011625 Pterygium Tretinoin 4.7616723453
MESH:D011629 Puberty, Precocious bisphenol A 4.7510548101
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.8412490602 11597910 12832656
MESH:D015427 Reperfusion Injury pirinixic acid 2.3619058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8018990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.0616283617 16116481
MESH:D012640 Seizures 2,4-dinitrotoluene 5.7718551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.7718551238
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.0518724381
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.4916192470
MESH:D012878 Skin Neoplasms Tretinoin 5.4916467112
MESH:D013088 Spermatocele Ethinyl Estradiol 3.9116709447
MESH:D013274 Stomach Neoplasms Tretinoin 1.8017261132
MESH:D013276 Stomach Ulcer Amiodarone 3.2818087811
MESH:D019966 Substance-Related Disorders bisphenol A 3.9516684133 16045194
MESH:D013610 Tachycardia Amiodarone 4.2511238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.1519225199
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1115669648
MESH:D013959 Thyroid Diseases Amiodarone 11.9619731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 11.9612697716
MESH:D013964 Thyroid Neoplasms Tretinoin 2.9917045167 16026305
MESH:D013971 Thyrotoxicosis Amiodarone 4.8218020914 19584973
MESH:D013978 Tibial Fractures Estradiol 4.6619048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.7516051514
MESH:D016171 Torsades de Pointes Amiodarone 4.1511989578 17467628
MESH:D014376 Tuberculosis Tretinoin 3.2016040207
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 4.9516049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 4.9516049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.8710091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.8710091137
MESH:D014581 Urticaria Acetaminophen 2.9410982225
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.6416129372
MESH:D014591 Uterine Diseases bisphenol A 4.9814652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2614692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.5816752155
MESH:D014605 Uveitis Cyclosporine 3.961336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5712125929
MESH:D014689 Venous Insufficiency coumarin 5.7512708602
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5015869587 14671159
MESH:D014820 Vitiligo Tretinoin 4.0216761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2215886252
MESH:D015430 Weight Gain Dietary Fats 3.7016723640
MESH:D009396 Wilms Tumor Tretinoin 3.9316287080
MESH:D014985 Xerophthalmia Cyclosporine 4.4117120751
Pathway ID Pathway Name
KEGG:00310 Lysine degradation
REACT:13 Metabolism of amino acids and derivatives
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA25274
    • No data
    No data
    Releated drug ID Related drug Name
    PA449789glycine
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00126 - Vitamin C Antioxidants;Essential Vitamins;Free Radical Scavengers;Vitamins (Vitamin C);Vitamins
    DB00139 - Ubicoenzyme Anti-Ulcer Agents;Dietary supplement;Micronutrient;Radiation-Protective Agents
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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