AutismKB 2.0

Annotation Detail for FYTTD1


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Basic Information Top
Gene Symbol:FYTTD1 ( DKFZp761B1514 )
Gene Full Name: forty-two-three domain containing 1
Band: 3q29
Quick LinksEntrez ID:84248; OMIM: NA; Uniprot ID:UIF_HUMAN; ENSEMBL ID: ENSG00000122068; HGNC ID: 25407
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of FYTTD1 mRNAaffects expression 21346803
C016601 4-hydroxytamoxifen 4-hydroxytamoxifen results in decreased expression of FYTTD1 mRNAdecreases expression 16514628
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of FYTTD1 mRNAdecreases expression 20018196
D016572 Cyclosporine Cyclosporine results in increased expression of FYTTD1 mRNAincreases expression 20106945
D004958 Estradiol Estradiol results in increased expression of FYTTD1 mRNAincreases expression 16514628
C070081 fulvestrant fulvestrant results in decreased expression of FYTTD1 mRNAdecreases expression 16514628
D020849 Raloxifene Raloxifene results in decreased expression of FYTTD1 mRNAdecreases expression 16514628
C025643 vinclozolin vinclozolin affects the expression of FYTTD1 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Estradiol 2.1411473722
MESH:D000419 Albuminuria Raloxifene 4.8817308373 17451421
MESH:D000544 Alzheimer Disease Raloxifene 2.5815800139
MESH:D001008 Anxiety Disorders vinclozolin 3.8319015723
MESH:D001284 Atrophy fulvestrant 5.1311514358
MESH:D001930 Brain Injuries Raloxifene 4.7816580743
MESH:D001943 Breast Neoplasms Estradiol 2.0612948864 19861407 17289903 18497071 16675129 14630087 17018787 17261762
MESH:D001943 Breast Neoplasms fulvestrant 2.0618984771
MESH:D001943 Breast Neoplasms Raloxifene 2.0615775269 15572757 17595753 17893378 17952589 15758505 17440819 16912660 16837676 17242785 17049068 17261762
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.8016111702
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 3.0516705839
MESH:D006528 Carcinoma, Hepatocellular Estradiol 3.0516924424
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 4.3017572228
MESH:D002318 Cardiovascular Diseases Raloxifene 3.6015775269
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 12.0820889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 12.0812371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 12.0818566989
MESH:D002779 Cholestasis Cyclosporine 3.0919486331
MESH:D003072 Cognition Disorders Raloxifene 4.9215800139
MESH:D003456 Cryptorchidism vinclozolin 4.6214966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.3218551238
MESH:D003865 Depressive Disorder, Major Raloxifene 4.3817474826
MESH:D003928 Diabetic Nephropathies Estradiol 9.7319279558
MESH:D003928 Diabetic Nephropathies Raloxifene 9.7317308373 17451421 15920148
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 2.0221346803 18551238
MESH:D004487 Edema Raloxifene 3.5815860553
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 4.2815845917
MESH:D016889 Endometrial Neoplasms 4-hydroxytamoxifen 8.2819148513
MESH:D016889 Endometrial Neoplasms Estradiol 8.2811473722 19148513 18566989
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1220426865
MESH:D005234 Fatty Liver Cyclosporine 8.6919224547
MESH:D005234 Fatty Liver Raloxifene 8.6917473493
MESH:D005355 Fibrosis Cyclosporine 3.4512639820 12168785
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.2716973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.6816417039
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.568708960
MESH:D006331 Heart Diseases Raloxifene 3.6911110106
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.7615720958
MESH:D006558 Herpes Genitalis Estradiol 5.4115709030
MESH:D019584 Hot Flashes Estradiol 4.1317088409
MESH:D006973 Hypertension Cyclosporine 5.5610903974
MESH:D006973 Hypertension Raloxifene 5.5617577099 15787275
MESH:D007248 Infertility, Male fulvestrant 7.6411514358
MESH:D007248 Infertility, Male vinclozolin 7.6416467254
MESH:D007333 Insulin Resistance Estradiol 3.1116627594 16393666
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.8215604871
MESH:D007674 Kidney Diseases Cyclosporine 6.3618776723 10903974 8314463
MESH:D007674 Kidney Diseases Estradiol 6.3615618244
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 13.5716705839
MESH:D007680 Kidney Neoplasms Cyclosporine 13.5712371664
MESH:D007680 Kidney Neoplasms Estradiol 13.5715610895
MESH:D007889 Leiomyoma Raloxifene 4.7616973256
MESH:D007984 Leydig Cell Tumor vinclozolin 5.0716417039
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 1.6814659978 14716833
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.7017203775 11807958 11408345 16891317
MESH:D020149 Manganese Poisoning Estradiol 4.8619453300
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.1616801185
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.9315863610
MESH:D009101 Multiple Myeloma Raloxifene 3.6016497877
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.4616810080
MESH:D009232 Myxoma Raloxifene 5.9316343187
MESH:D009336 Necrosis 2,4-dinitrotoluene 4.2018551238
MESH:D009389 Neovascularization, Pathologic Estradiol 4.0717289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.8217954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5019348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 3.9311399458 16427766
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.6616049721 12819281
MESH:D010024 Osteoporosis Raloxifene 3.5315775268 17882678 19059307
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.4917823083 15579764 15758505 17893378
MESH:D010051 Ovarian Neoplasms Estradiol 2.2819401270
MESH:D011230 Precancerous Conditions Cyclosporine 3.4412371664
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 4.2318220299 19015723 18042343
MESH:D011469 Prostatic Diseases vinclozolin 5.2718220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.1320887781
MESH:D011471 Prostatic Neoplasms Estradiol 3.2916740699
MESH:D011471 Prostatic Neoplasms Raloxifene 3.2915731164 16220300 16536755
MESH:D011472 Prostatitis vinclozolin 5.2718629315
MESH:D011565 Psoriasis Cyclosporine 2.3016882103
MESH:D011693 Purpura Raloxifene 5.9315770314
MESH:D012640 Seizures 2,4-dinitrotoluene 2.6818551238
MESH:D020521 Stroke Raloxifene 4.0116837676
MESH:D013978 Tibial Fractures Estradiol 15.0019048282
MESH:D013978 Tibial Fractures Raloxifene 15.0019048282
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 5.4716049721
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 5.4717572228
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.6510091137
MESH:D014605 Uveitis Cyclosporine 4.361336536
MESH:D054556 Venous Thromboembolism Raloxifene 5.5816837676
MESH:D014846 Vulvar Neoplasms Raloxifene 5.9316343187
MESH:D014985 Xerophthalmia Cyclosporine 4.8217120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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