AutismKB 2.0

Annotation Detail for SGIP1


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Basic Information Top
Gene Symbol:SGIP1 ( DKFZp686A16142,DKFZp761D221,FLJ33378,FLJ43054 )
Gene Full Name: SH3-domain GRB2-like (endophilin) interacting protein 1
Band: 1p31.3
Quick LinksEntrez ID:84251; OMIM: 611540; Uniprot ID:SGIP1_HUMAN; ENSEMBL ID: ENSG00000118473; HGNC ID: 25412
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of SGIP1 mRNAaffects expression 20382639
D015735 Mifepristone Mifepristone results in increased expression of SGIP1 mRNAincreases expression 17584828
C025643 vinclozolin vinclozolin affects the expression of SGIP1 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D001008 Anxiety Disorders vinclozolin 4.0019015723
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0120889678
MESH:D003456 Cryptorchidism vinclozolin 4.9314966744
MESH:D004715 Endometriosis Mifepristone 4.8116134523
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1520426865
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.6816973722
MESH:D005832 Genital Diseases, Male vinclozolin 6.1716417039
MESH:D007248 Infertility, Male vinclozolin 3.3216467254
MESH:D007984 Leydig Cell Tumor vinclozolin 5.4716417039
MESH:D010051 Ovarian Neoplasms Mifepristone 3.2316525653
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 4.6418042343 18220299 19015723
MESH:D011469 Prostatic Diseases vinclozolin 5.6818220299
MESH:D011472 Prostatitis vinclozolin 5.6818629315
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018