Annotation Detail for HAGHL
Basic Information Top
| Gene Symbol: | HAGHL ( MGC2605 ) |
|---|---|
| Gene Full Name: | hydroxyacylglutathione hydrolase-like |
| Band: | 16p13.3 |
| Quick Links | Entrez ID:84264; OMIM: NA; Uniprot ID:HAGHL_HUMAN; ENSEMBL ID: ENSG00000103253; HGNC ID: 14177 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Diseases/Disorders| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of HAGHL mRNA | affects expression | 17562736 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride affects the expression of HAGHL mRNA | affects expression | 17484886 |
| D004041 | Dietary Fats | Dietary Fats results in increased expression of HAGHL mRNA | increases expression | 18042831 |
| C041786 | palm oil | palm oil results in increased expression of HAGHL mRNA | increases expression | 18042831 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 4.57 | 10982225 | |
| MESH:D001161 | Arteriosclerosis | Dietary Fats | 4.45 | 15238619 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.40 | 18445737 | |
| MESH:D001943 | Breast Neoplasms | Dietary Fats | 2.24 | 20435547 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Carbon Tetrachloride | 4.34 | 15673190 3786805 16227642 16050911 15721981 16124888 15700767 16192424 16097048 16011737 18705752 10355542 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 2.99 | 3084413 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Carbon Tetrachloride | 2.99 | 18788625 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.79 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 4.05 | 17562736 14550746 19923254 11739529 19164858 10774834 2444490 11743745 16393943 12153990 19370779 12540782 12594235 12392966 16485898 18713872 17522070 11529661 11287661 19420014 18071297 15619225 16177239 10663392 17906064 16781746 15968718 10915739 16081117 14725611 19416960 11421492 11461765 12958197 14986274 19085960 19739265 16109766 11834606 12705907 16227642 | |
| MESH:D056486 | Drug-Induced Liver Injury | Carbon Tetrachloride | 4.05 | 3732212 17522070 7120509 7440962 6623471 4309450 3786805 11566570 15998439 10915739 19336974 15968718 10092053 19085960 15027814 16227642 7179309 21278145 6884620 2869522 16177239 9327722 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.82 | 19426721 | |
| MESH:D050171 | Dyslipidemias | Dietary Fats | 3.73 | 18367378 | |
| MESH:D005234 | Fatty Liver | Carbon Tetrachloride | 9.29 | 16045604 12631006 61145 15959796 17595544 12795759 16239168 19224547 | |
| MESH:D005234 | Fatty Liver | Dietary Fats | 9.29 | 18296743 17967931 19004024 19551842 | |
| MESH:D005355 | Fibrosis | Carbon Tetrachloride | 10.74 | 18705752 | |
| MESH:D005355 | Fibrosis | Dietary Fats | 10.74 | 18296743 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.40 | 16983495 | |
| MESH:D006505 | Hepatitis | Carbon Tetrachloride | 4.10 | 19110552 19900420 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.02 | 16870215 | |
| MESH:D006932 | Hyperbilirubinemia | Carbon Tetrachloride | 5.16 | 16899240 | |
| MESH:D006937 | Hypercholesterolemia | Dietary Fats | 4.02 | 21332399 | |
| MESH:D006949 | Hyperlipidemias | Dietary Fats | 4.08 | 21332399 | |
| MESH:D006975 | Hypertension, Portal | Carbon Tetrachloride | 4.65 | 15338365 | |
| MESH:D007249 | Inflammation | Dietary Fats | 2.60 | 20412841 | |
| MESH:D007333 | Insulin Resistance | Dietary Fats | 3.34 | 18457598 11836018 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.40 | 15629191 12587719 | |
| MESH:D008103 | Liver Cirrhosis | Carbon Tetrachloride | 7.27 | 11903743 17157831 11408273 16221502 16943688 21278145 17174718 16239168 17334410 | |
| MESH:D008103 | Liver Cirrhosis | Dietary Fats | 7.27 | 18296743 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Carbon Tetrachloride | 1.75 | 12741479 17761835 18166357 18054572 12667390 15818738 14716833 12632514 17944888 17481882 17976157 16638106 17525996 15730626 17766677 17869086 17631135 15673190 18279442 17714472 15996030 12898905 12586293 18412020 15959796 12546737 18395095 18395914 18429990 18376398 18339082 18251166 16097048 15338365 18317297 17922224 16033810 18210741 18481824 14512876 18420326 15370692 18156304 16015684 15650968 12445418 18418968 15931870 16192424 15925388 18705752 12649538 16027843 17805973 15123356 17708605 12632512 18006644 15876570 14620537 17640975 12389079 17565644 18472094 15362042 17698563 17721639 16248980 12445421 16136751 12609069 14748882 17900296 15052691 10355542 18277467 16011737 14716496 18205269 12666154 18187930 18472332 16116963 17823541 12958196 20821823 15893842 15057751 18263696 14724832 11481614 17557913 13678700 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 4.16 | 16611625 19460945 16610002 19014921 12587719 19784758 11587558 12969438 | |
| MESH:D008107 | Liver Diseases | Carbon Tetrachloride | 4.16 | 16246199 15830285 16964402 17285989 15720792 | |
| MESH:D017093 | Liver Failure | Carbon Tetrachloride | 4.73 | 15123358 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 10.75 | 16871587 17185352 | |
| MESH:D017114 | Liver Failure, Acute | Carbon Tetrachloride | 10.75 | 14706259 16899240 | |
| MESH:D008113 | Liver Neoplasms | Carbon Tetrachloride | 2.34 | 19294768 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Carbon Tetrachloride | 2.84 | 12014681 15583823 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.13 | 19513568 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.21 | 18514411 | |
| MESH:D009765 | Obesity | Dietary Fats | 2.36 | 17217161 20132043 21332399 20518802 18457598 16723640 11836018 18674790 19632207 | |
| MESH:D010146 | Pain | Acetaminophen | 2.73 | 16870215 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.44 | 10982225 | |
| MESH:D015430 | Weight Gain | Dietary Fats | 4.11 | 16723640 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:00620 | Pyruvate metabolism |