Annotation Detail for RNF135
Basic Information Top
| Gene Symbol: | RNF135 ( MGC13061,REUL,Riplet ) |
|---|---|
| Gene Full Name: | ring finger protein 135 |
| Band: | 17q11.2 |
| Quick Links | Entrez ID:84282; OMIM: 611358; Uniprot ID:RN135_HUMAN; ENSEMBL ID: ENSG00000181481; HGNC ID: 21158 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| No data |
| No data |
| Desease Name |
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| height |
| DEVELOPMENTAL |
| No data |
| Desease Name |
|---|
| Overgrowth syndrome |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of RNF135 mRNA | affects expression | 17562736 |
| D004041 | Dietary Fats | Dietary Fats results in decreased expression of RNF135 mRNA | decreases expression | 18042831 |
| C041786 | palm oil | palm oil results in decreased expression of RNF135 mRNA | decreases expression | 18042831 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 4.71 | 10982225 | |
| MESH:D001161 | Arteriosclerosis | Dietary Fats | 4.54 | 15238619 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D001943 | Breast Neoplasms | Dietary Fats | 2.24 | 20435547 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.81 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 17522070 16781746 19420014 11739529 12958197 11529661 17906064 12540782 16109766 18071297 19085960 12153990 19739265 11743745 16227642 19416960 12392966 10774834 14986274 11461765 16177239 19370779 11421492 12594235 10915739 18713872 11834606 14725611 16081117 17562736 15619225 16393943 11287661 19164858 15968718 10663392 14550746 12705907 19923254 16485898 2444490 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.96 | 19426721 | |
| MESH:D050171 | Dyslipidemias | Dietary Fats | 3.76 | 18367378 | |
| MESH:D005234 | Fatty Liver | Dietary Fats | 3.72 | 18296743 19004024 17967931 19551842 | |
| MESH:D005355 | Fibrosis | Dietary Fats | 4.17 | 18296743 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.54 | 16983495 | |
| MESH:D006130 | Growth Disorders | marker/mechanism | 17632510 | ||
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.06 | 16870215 | |
| MESH:D006937 | Hypercholesterolemia | Dietary Fats | 4.08 | 21332399 | |
| MESH:D006949 | Hyperlipidemias | Dietary Fats | 4.14 | 21332399 | |
| MESH:D007249 | Inflammation | Dietary Fats | 2.62 | 20412841 | |
| MESH:D007333 | Insulin Resistance | Dietary Fats | 3.37 | 11836018 18457598 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.42 | 15629191 12587719 | |
| MESH:D008103 | Liver Cirrhosis | Dietary Fats | 3.09 | 18296743 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 19784758 19014921 12969438 11587558 12587719 16611625 16610002 19460945 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.68 | 17185352 16871587 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.22 | 19513568 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.26 | 18514411 | |
| MESH:D009765 | Obesity | Dietary Fats | 2.36 | 21332399 11836018 19632207 18457598 18674790 16723640 20518802 20132043 17217161 | |
| MESH:D010146 | Pain | Acetaminophen | 2.77 | 16870215 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.50 | 10982225 | |
| MESH:D015430 | Weight Gain | Dietary Fats | 4.15 | 16723640 |
| Pathway ID | Pathway Name |
|---|---|
| REACT:6900 | Signaling in Immune system |