AutismKB 2.0

Annotation Detail for PHF6


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Basic Information Top
Gene Symbol:PHF6 ( BORJ,MGC14797 )
Gene Full Name: PHD finger protein 6
Band: Xq26.2
Quick LinksEntrez ID:84295; OMIM: 300414; Uniprot ID:PHF6_HUMAN; ENSEMBL ID: ENSG00000156531; HGNC ID: 18145
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
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Desease Name
Borjeson-Forssman-Lehmann syndrome
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C014949 acetylhydrazine acetylhydrazine results in decreased expression of PHF6 mRNAdecreases expression 15282401
D019259 Lamivudine [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of PHF6 mRNAaffects cotreatment|decreases expression 16931933
D019259 Lamivudine [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of PHF6 mRNAaffects cotreatment|decreases expression 16931933
D019259 Lamivudine [Zidovudine co-treated with Lamivudine] results in decreased expression of PHF6 mRNAaffects cotreatment|decreases expression 16931933
D019469 Indinavir [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of PHF6 mRNAaffects cotreatment|decreases expression 16931933
D019258 Saquinavir [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of PHF6 mRNAaffects cotreatment|decreases expression 16931933
D015215 Zidovudine [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of PHF6 mRNAaffects cotreatment|decreases expression 16931933
D015215 Zidovudine [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of PHF6 mRNAaffects cotreatment|decreases expression 16931933
D015215 Zidovudine [Zidovudine co-treated with Lamivudine] results in decreased expression of PHF6 mRNAaffects cotreatment|decreases expression 16931933
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 5.319612607
MESH:C536575 Borjeson-Forssman-Lehmann syndrome marker/mechanism
MESH:D004362 Drug Toxicity Lamivudine 9.6715040536
MESH:D004362 Drug Toxicity Zidovudine 9.6715040536
MESH:D005234 Fatty Liver Zidovudine 4.2818299183
MESH:D006402 Hematologic Diseases Zidovudine 5.1212579204
MESH:D006509 Hepatitis B Lamivudine 5.4717703166
MESH:D019694 Hepatitis B, Chronic Lamivudine 5.4716476009 15274664 12044531 15309715 15631357
MESH:D015658 HIV Infections Indinavir 16.8815388451 11141242 11363243
MESH:D015658 HIV Infections Lamivudine 16.8817530837 11141242 20032539 9296927
MESH:D015658 HIV Infections Saquinavir 16.8811141242 15388451
MESH:D015658 HIV Infections Zidovudine 16.8811363243 11141242 11698656 20032539 17358032
MESH:D007680 Kidney Neoplasms Zidovudine 4.0912579204
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 4.7920370541
MESH:D008175 Lung Neoplasms Zidovudine 2.4918800350
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 6.4517358032
MESH:D009164 Mycobacterium Infections Indinavir 6.0221442799
MESH:D054218 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma marker/mechanism 20228800
MESH:D012206 Rhabdomyolysis Lamivudine 6.089296927
MESH:D013274 Stomach Neoplasms Zidovudine 2.4817696246
MESH:D014625 Vaginal Neoplasms Zidovudine 5.2412579204
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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