AutismKB 2.0

Annotation Detail for HVCN1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:HVCN1 ( HV1,MGC15619,VSOP )
Gene Full Name: hydrogen voltage-gated channel 1
Band: 12q24.11
Quick LinksEntrez ID:84329; OMIM: 611227; Uniprot ID:HVCN1_HUMAN; ENSEMBL ID: ENSG00000122986; HGNC ID: 28240
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of HVCN1 mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 5.2610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8610977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6911461765 19420014 14986274 14550746 11287661 12153990 19416960 11529661 11834606 12392966 16227642 10774834 18071297 17562736 17522070 19164858 11421492 19370779 19739265 16485898 14725611 16393943 17906064 11739529 16781746 10663392 10915739 19923254 15968718 2444490 12705907 11743745 12958197 12540782 16081117 15619225 16109766 18713872 19085960 12594235 16177239
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.5119426721
MESH:D005756 Gastritis Acetaminophen 5.0916983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1516870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4712587719 15629191
MESH:D008107 Liver Diseases Acetaminophen 1.7219460945 12587719 19014921 11587558 19784758 16610002 12969438 16611625
MESH:D017114 Liver Failure, Acute Acetaminophen 3.8117185352 16871587
MESH:D008546 Melanoma, Experimental Acetaminophen 4.4719513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3618514411
MESH:D010146 Pain Acetaminophen 2.8716870215
MESH:D014581 Urticaria Acetaminophen 3.6710982225
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018