AutismKB 2.0

Annotation Detail for GFM2


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Basic Information Top
Gene Symbol:GFM2 ( EF-G2mt,EFG2,MRRF2,MST027,RRF2,RRF2mt,hEFG2,mEF-G 2 )
Gene Full Name: G elongation factor, mitochondrial 2
Band: 5q13.3
Quick LinksEntrez ID:84340; OMIM: 606544; Uniprot ID:RRF2M_HUMAN; ENSEMBL ID: ENSG00000164347; HGNC ID: 29682
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of GFM2 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of GFM2 mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.9110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 2.9916705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.993084413
MESH:D002386 Cataract Acetaminophen 2.8310977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.096135515
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.7818551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 4.0821346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.0819370779 17522070 10663392 11461765 16485898 10915739 11529661 19416960 19164858 16177239 12594235 12705907 11739529 15968718 12392966 16227642 16393943 16781746 11743745 14725611 12153990 19739265 18713872 16081117 12540782 11421492 19923254 16109766 2444490 11834606 17562736 12958197 14550746 18071297 19420014 11287661 14986274 19085960 10774834 17906064 15619225
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.1719426721
MESH:D005756 Gastritis Acetaminophen 4.7416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1116870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4412587719 15629191
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.4116705839
MESH:D008107 Liver Diseases Acetaminophen 1.7112969438 16611625 19784758 16610002 11587558 12587719 19460945 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.7416871587 17185352
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.297678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.822876784 2876786 6135515
MESH:D008546 Melanoma, Experimental Acetaminophen 4.3319513568
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.757678174 18551238
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3118514411
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.9416049721
MESH:D010146 Pain Acetaminophen 2.8216870215
MESH:D012640 Seizures 2,6-dinitrotoluene 2.8518551238
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.4316049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 5.2010091137
MESH:D014581 Urticaria Acetaminophen 3.5810982225
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018