AutismKB 2.0

Annotation Detail for ZNF559


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Basic Information Top
Gene Symbol:ZNF559 ( MGC13105,Nbla00121 )
Gene Full Name: zinc finger protein 559
Band: 19p13.2
Quick LinksEntrez ID:84527; OMIM: NA; Uniprot ID:ZN559_HUMAN; ENSEMBL ID: ENSG00000188321; HGNC ID: 28197
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ZNF559 mRNAdecreases expression 20018196
D016572 Cyclosporine Cyclosporine results in increased expression of ZNF559 mRNAincreases expression 20106945
C014347 decitabine decitabine results in increased expression of ZNF559 mRNAincreases expression 16367923
C116926 rofecoxib rofecoxib results in decreased expression of ZNF559 mRNAdecreases expression 17070997
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D001169 Arthritis, Experimental rofecoxib 4.5716690336
MESH:D001943 Breast Neoplasms decitabine 2.5318320071 19208741
MESH:D002294 Carcinoma, Squamous Cell decitabine 2.6819215824
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.4420889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.4412371664
MESH:D002779 Cholestasis Cyclosporine 3.2119486331
MESH:D003110 Colonic Neoplasms decitabine 4.4517616700
MESH:D003110 Colonic Neoplasms rofecoxib 4.4512902858
MESH:D015179 Colorectal Neoplasms decitabine 2.1118981723
MESH:D004701 Endocrine Gland Neoplasms decitabine 5.8419294695
MESH:D004715 Endometriosis rofecoxib 5.2515652904
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1520426865
MESH:D005234 Fatty Liver Cyclosporine 3.2819224547
MESH:D005355 Fibrosis Cyclosporine 3.7012639820 12168785
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.858708960
MESH:D006258 Head and Neck Neoplasms decitabine 3.7419215824
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.0515720958
MESH:D006973 Hypertension Cyclosporine 2.2110903974
MESH:D007248 Infertility, Male decitabine 3.4517581917
MESH:D007410 Intestinal Diseases rofecoxib 5.5915831440
MESH:D007417 Intestinal Polyps rofecoxib 5.8311245490
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.1615604871
MESH:D007674 Kidney Diseases Cyclosporine 2.548314463 10903974 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0812371664
MESH:D007938 Leukemia decitabine 3.2419235587 18980019
MESH:D007951 Leukemia, Myeloid decitabine 4.4317236224 19117987 18454857
MESH:D015470 Leukemia, Myeloid, Acute decitabine 2.4317679729 18704418 18460780 19387464 19010910 18206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 6.1918055864
MESH:D008106 Liver Cirrhosis, Experimental rofecoxib 3.0817565644
MESH:D008223 Lymphoma decitabine 3.6919470736
MESH:D008545 Melanoma decitabine 2.2816505122 17785578
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.5116801185
MESH:D009101 Multiple Myeloma decitabine 3.6218172295
MESH:D009190 Myelodysplastic Syndromes decitabine 3.5818608210 16882708 19157545 19010910
MESH:D009369 Neoplasms decitabine 2.8719116145 19470736 17925555
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.1617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6519348381 18481113
MESH:D010003 Osteoarthritis rofecoxib 4.5916690336
MESH:D010051 Ovarian Neoplasms decitabine 2.7419331143 19259094
MESH:D010149 Pain, Postoperative rofecoxib 6.1116678543 18165598
MESH:D010190 Pancreatic Neoplasms decitabine 2.8719294695
MESH:D011230 Precancerous Conditions Cyclosporine 3.5912371664
MESH:D055728 Primary Myelofibrosis decitabine 5.2917616702
MESH:D011565 Psoriasis Cyclosporine 2.3316882103
MESH:D012208 Rhabdomyosarcoma decitabine 4.8719155313
MESH:D013274 Stomach Neoplasms marker/mechanism 16367923
MESH:D013274 Stomach Neoplasms decitabine 2.1019037991
MESH:D013964 Thyroid Neoplasms decitabine 3.6317967635
MESH:D001749 Urinary Bladder Neoplasms decitabine 2.8419087683 17616700
MESH:D014604 Uveal Neoplasms decitabine 5.6417785578
MESH:D014605 Uveitis Cyclosporine 4.711336536
MESH:D014985 Xerophthalmia Cyclosporine 5.1617120751
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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