Annotation Detail for AFAP1L2
Basic Information Top
| Gene Symbol: | AFAP1L2 ( FLJ14564,KIAA1914,XB130 ) |
|---|---|
| Gene Full Name: | actin filament associated protein 1-like 2 |
| Band: | 10q25.3 |
| Quick Links | Entrez ID:84632; OMIM: 612420; Uniprot ID:AF1L2_HUMAN; ENSEMBL ID: ENSG00000169129; HGNC ID: 25901 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| No data |
| No data |
| Desease Name |
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| NEUROLOGICAL |
| Cognitive performance |
| Desease Name |
|---|
| Cognitive test performance |
| No data |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of AFAP1L2 mRNA | affects expression | 17562736 |
| D004041 | Dietary Fats | Dietary Fats results in increased expression of AFAP1L2 mRNA | increases expression | 18042831 |
| C041786 | palm oil | palm oil results in increased expression of AFAP1L2 mRNA | increases expression | 18042831 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 4.71 | 10982225 | |
| MESH:D001161 | Arteriosclerosis | Dietary Fats | 4.54 | 15238619 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D001943 | Breast Neoplasms | Dietary Fats | 2.24 | 20435547 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.81 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 19164858 11743745 15619225 18713872 16393943 11529661 2444490 11739529 17522070 14725611 12392966 16781746 17562736 19416960 19923254 14550746 19420014 12540782 19370779 18071297 16485898 10663392 12594235 10774834 11421492 12153990 10915739 11461765 15968718 19085960 14986274 17906064 12958197 12705907 16109766 16081117 11834606 16227642 16177239 19739265 11287661 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.96 | 19426721 | |
| MESH:D050171 | Dyslipidemias | Dietary Fats | 3.76 | 18367378 | |
| MESH:D005234 | Fatty Liver | Dietary Fats | 3.72 | 19004024 19551842 18296743 17967931 | |
| MESH:D005355 | Fibrosis | Dietary Fats | 4.17 | 18296743 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.54 | 16983495 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.06 | 16870215 | |
| MESH:D006937 | Hypercholesterolemia | Dietary Fats | 4.08 | 21332399 | |
| MESH:D006949 | Hyperlipidemias | Dietary Fats | 4.14 | 21332399 | |
| MESH:D007249 | Inflammation | Dietary Fats | 2.62 | 20412841 | |
| MESH:D007333 | Insulin Resistance | Dietary Fats | 3.37 | 11836018 18457598 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.42 | 15629191 12587719 | |
| MESH:D008103 | Liver Cirrhosis | Dietary Fats | 3.09 | 18296743 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 16611625 16610002 12969438 12587719 19784758 19014921 19460945 11587558 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.68 | 17185352 16871587 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.22 | 19513568 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.26 | 18514411 | |
| MESH:D009765 | Obesity | Dietary Fats | 2.36 | 20518802 21332399 18674790 11836018 19632207 18457598 17217161 16723640 20132043 | |
| MESH:D010146 | Pain | Acetaminophen | 2.77 | 16870215 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.50 | 10982225 | |
| MESH:D015430 | Weight Gain | Dietary Fats | 4.15 | 16723640 |
| No data |