AutismKB 2.0

Annotation Detail for MYPN


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Basic Information Top
Gene Symbol:MYPN ( MYOP )
Gene Full Name: myopalladin
Band: 10q21.3
Quick LinksEntrez ID:84665; OMIM: 608517; Uniprot ID:MYPN_HUMAN; ENSEMBL ID: ENSG00000138347; HGNC ID: 23246
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
CHEMDEPENDENCY
smoking cessation
Desease Name
Optic disc size (disc)
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of MYPN mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 5.2610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8610977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6919923254 10774834 11461765 19370779 16109766 10663392 15619225 11529661 2444490 16393943 16781746 19164858 14725611 17562736 14986274 12392966 10915739 12153990 12958197 18713872 17522070 12540782 11421492 12705907 19416960 12594235 19739265 14550746 11287661 11743745 16081117 16485898 11834606 19420014 15968718 18071297 19085960 11739529 16227642 17906064 16177239
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.5119426721
MESH:D005756 Gastritis Acetaminophen 5.0916983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1516870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4715629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7212587719 16611625 11587558 12969438 16610002 19460945 19784758 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.8116871587 17185352
MESH:D008546 Melanoma, Experimental Acetaminophen 4.4719513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3618514411
MESH:D010146 Pain Acetaminophen 2.8716870215
MESH:D014581 Urticaria Acetaminophen 3.6710982225
No data
Pharmacogenomics Knowledge Base Top
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018