Annotation Detail for PPP1R9B

Basic Information
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Gene Symbol: | PPP1R9B ( FLJ30345,PPP1R6,PPP1R9,SPINO,Spn ) |
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Gene Full Name: | protein phosphatase 1, regulatory (inhibitor) subunit 9B |
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Band: | 17q21.33 |
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Quick Links | Entrez ID:84687; OMIM: 603325; Uniprot ID:NEB2_HUMAN; ENSEMBL ID: ENSG00000108819; HGNC ID: 9298 |
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Relate to Another Database: |
SFARIGene;
denovo-db |
Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
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C062865 |
2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline |
2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline inhibits the reaction [Estradiol results in increased expression of PPP1R9B protein] | decreases reaction|increases expression | 17443789
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D000643 |
Ammonium Chloride |
Ammonium Chloride affects the expression of PPP1R9B mRNA | affects expression | 16483693
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D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of PPP1R9B mRNA | decreases expression | 20382639
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D004958 |
Estradiol |
2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline inhibits the reaction [Estradiol results in increased expression of PPP1R9B protein] | decreases reaction|increases expression | 17443789
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D004958 |
Estradiol |
CREB1 protein promotes the reaction [Estradiol results in increased expression of PPP1R9B protein] | increases expression|increases reaction | 15802184
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D004958 |
Estradiol |
Estradiol results in increased expression of PPP1R9B protein | increases expression | 15802184 17443789
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D005419 |
Flavonoids |
Flavonoids results in increased expression of PPP1R9B mRNA | increases expression | 18035473
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D007608 |
Kainic Acid |
Kainic Acid results in increased expression of PPP1R9B protein | increases expression | 17443789
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C488333 |
Ro 65-7199 |
Ro 65-7199 affects the expression of PPP1R9B mRNA | affects expression | 14610520
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C488334 |
Ro 66-0074 |
Ro 66-0074 affects the expression of PPP1R9B mRNA | affects expression | 14610520
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Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
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MESH:D000138 |
Acidosis |
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Ammonium Chloride |
3.90 | 18287403 |
MESH:D000230 |
Adenocarcinoma |
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Estradiol |
2.14 | 11473722 |
MESH:D001943 |
Breast Neoplasms |
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Estradiol |
2.12 | 14630087 17289903 17261762 12948864 18497071 16675129 19861407 17018787 |
MESH:D002181 |
Candidiasis, Vulvovaginal |
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Estradiol |
4.80 | 16111702 |
MESH:D006528 |
Carcinoma, Hepatocellular |
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Estradiol |
1.78 | 16924424 |
MESH:D002471 |
Cell Transformation, Neoplastic |
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7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7.18 | 20889678 |
MESH:D002471 |
Cell Transformation, Neoplastic |
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Estradiol |
7.18 | 18566989 |
MESH:D003928 |
Diabetic Nephropathies |
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Estradiol |
3.63 | 19279558 |
MESH:D016889 |
Endometrial Neoplasms |
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Estradiol |
3.13 | 18566989 11473722 19148513 |
MESH:D004938 |
Esophageal Neoplasms |
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7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.12 | 20426865 |
MESH:D006558 |
Herpes Genitalis |
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Estradiol |
5.41 | 15709030 |
MESH:D019584 |
Hot Flashes |
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Estradiol |
4.13 | 17088409 |
MESH:D007249 |
Inflammation |
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Flavonoids |
2.75 | 17296493 |
MESH:D007333 |
Insulin Resistance |
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Estradiol |
3.11 | 16393666 16627594 |
MESH:D007674 |
Kidney Diseases |
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Estradiol |
2.71 | 15618244 |
MESH:D007680 |
Kidney Neoplasms |
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Estradiol |
3.18 | 15610895 |
MESH:D008106 |
Liver Cirrhosis, Experimental |
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Estradiol |
1.68 | 14659978 14716833 |
MESH:D008325 |
Mammary Neoplasms, Experimental |
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Estradiol |
2.70 | 11408345 11807958 16891317 17203775 |
MESH:D020149 |
Manganese Poisoning |
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Estradiol |
4.86 | 19453300 |
MESH:D015428 |
Myocardial Reperfusion Injury |
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Estradiol |
3.46 | 16810080 |
MESH:D009389 |
Neovascularization, Pathologic |
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Estradiol |
4.07 | 17289903 |
MESH:D009421 |
Nervous System Malformations |
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Estradiol |
3.93 | 16427766 11399458 |
MESH:D010051 |
Ovarian Neoplasms |
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Estradiol |
2.28 | 19401270 |
MESH:D010146 |
Pain |
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2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline |
6.24 | 15275824 |
MESH:D019048 |
Prostatic Intraepithelial Neoplasia |
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Estradiol |
4.13 | 20887781 |
MESH:D011471 |
Prostatic Neoplasms |
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Estradiol |
3.04 | 16740699 |
MESH:D012640 |
Seizures |
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Kainic Acid |
4.52 | 18657176 19186208 17827730 16336964 15686955 1641125 10686065 14637104 19414003 |
MESH:D012893 |
Sleep Disorders |
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Kainic Acid |
6.03 | 19414003 |
MESH:D013978 |
Tibial Fractures |
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Estradiol |
5.06 | 19048282 |