AutismKB 2.0

Annotation Detail for MYO18B


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Basic Information Top
Gene Symbol:MYO18B ( DKFZp434C2422,DKFZp779C1668,FLJ41942 )
Gene Full Name: myosin XVIIIB
Band: 22q12.1
Quick LinksEntrez ID:84700; OMIM: 607295; Uniprot ID:MY18B_HUMAN; ENSEMBL ID: ENSG00000133454; HGNC ID: 18150
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
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Pathway IDPathway Name
P00044Nicotinic acetylcholine receptor signaling pathway
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
CHEMDEPENDENCY
smoking cessation
Desease Name
Schizophrenia, bipolar disorder and depression (combined)
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C026137 3-hydroxyacetanilide 3-hydroxyacetanilide results in decreased expression of MYO18B mRNAdecreases expression 18544908
D000082 Acetaminophen Acetaminophen affects the expression of MYO18B mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in decreased expression of MYO18B mRNAdecreases expression 18544908
D004041 Dietary Fats Dietary Fats results in decreased expression of MYO18B mRNAdecreases expression 18042831
C041786 palm oil palm oil results in decreased expression of MYO18B mRNAdecreases expression 18042831
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D001161 Arteriosclerosis Dietary Fats 4.4515238619
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms Dietary Fats 2.2420435547
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.7910977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.672444490 18071297 16485898 19416960 14986274 16781746 11743745 16109766 12392966 11287661 11739529 19739265 19420014 10915739 11834606 12705907 19923254 11461765 14550746 15968718 18713872 17522070 10774834 17906064 16393943 11421492 19164858 14725611 19370779 16081117 15619225 16177239 17562736 19085960 12153990 12594235 12958197 11529661 10663392 16227642 12540782
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:D050171 Dyslipidemias Dietary Fats 3.7318367378
MESH:D005234 Fatty Liver Dietary Fats 3.6617967931 18296743 19004024 19551842
MESH:D005355 Fibrosis Dietary Fats 4.0818296743
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D006937 Hypercholesterolemia Dietary Fats 4.0221332399
MESH:D006949 Hyperlipidemias Dietary Fats 4.0821332399
MESH:D007249 Inflammation Dietary Fats 2.6020412841
MESH:D007333 Insulin Resistance Dietary Fats 3.3411836018 18457598
MESH:D007674 Kidney Diseases Acetaminophen 2.4012587719 15629191
MESH:D008103 Liver Cirrhosis Dietary Fats 3.0718296743
MESH:D008107 Liver Diseases Acetaminophen 1.7011587558 16610002 12587719 16611625 19014921 12969438 19784758 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6316871587 17185352
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D008654 Mesothelioma therapeutic 17294804
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2118514411
MESH:D009765 Obesity Dietary Fats 2.3618457598 18674790 16723640 21332399 20518802 17217161 11836018 19632207 20132043
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D014581 Urticaria Acetaminophen 3.4410982225
MESH:D015430 Weight Gain Dietary Fats 4.1116723640
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018