Annotation Detail for BEX2
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of BEX2 mRNA | affects expression | 17562736
|
| D017638 |
Asbestos, Crocidolite |
Asbestos, Crocidolite results in increased expression of BEX2 mRNA | increases expression | 18687144
|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of BEX2 mRNA | affects binding|decreases expression|increases activity | 19710929
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.64 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.22 | 16434500 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.71 | 10982225 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.39 | 18445737 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.63 | 19483382 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
1.41 | 3084413 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.81 | 10977129 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.15 | 19176532 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.59 | 18249437 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
1.68 | 16227642 14725611 16109766 11739529 11287661 16781746 11421492 14550746 14986274 11461765 17522070 11743745 2444490 12705907 12594235 18071297 15968718 12540782 16081117 17906064 19164858 19416960 16177239 10663392 15619225 10774834 19085960 19370779 19923254 17562736 19739265 18713872 10915739 16485898 19420014 12392966 11834606 16393943 12958197 11529661 12153990 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.96 | 19426721 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.96 | 12083418 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.25 | 19236843 20131406 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.54 | 16983495 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.78 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.64 | 19176532 18467677 19772884 16221962 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
3.06 | 16870215 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.63 | 20558911 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.90 | 16306350 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.42 | 15629191 12587719 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.71 | 19460945 12969438 19784758 16611625 19014921 11587558 16610002 12587719 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.68 | 17185352 16871587 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.94 | 15890375 20007298 16377806 |
| MESH:D055370 |
Lung Injury |
|
Asbestos, Crocidolite |
4.67 | 17365036 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.22 | 19513568 |
| MESH:D008654 |
Mesothelioma |
|
Asbestos, Crocidolite |
3.32 | 16966607 18303189 16166281 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.16 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.29 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.29 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.12 | 17405874 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.26 | 18514411 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.89 | 20558911 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.77 | 16870215 |
| MESH:D010995 |
Pleural Diseases |
|
Asbestos, Crocidolite |
5.55 | 10923243 |
| MESH:D011658 |
Pulmonary Fibrosis |
|
Asbestos, Crocidolite |
3.16 | 17322281 15814490 17365031 17975199 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.56 | 19058328 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.50 | 10982225 |
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