AutismKB 2.0

Annotation Detail for HIRIP3


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Basic Information Top
Gene Symbol:HIRIP3 ( - )
Gene Full Name: HIRA interacting protein 3
Band: 16p11.2
Quick LinksEntrez ID:8479; OMIM: 603365; Uniprot ID:HIRP3_HUMAN; ENSEMBL ID: ENSG00000149929; HGNC ID: 4917
Relate to Another Database: SFARIGene; denovo-db
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of HIRIP3 mRNAaffects expression 17562736
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of HIRIP3 mRNAdecreases expression 17557909
D012643 Selenium Selenium results in increased expression of HIRIP3 mRNAincreases expression 19244175
C496197 trans-10,cis-12-conjugated linoleic acid trans-10,cis-12-conjugated linoleic acid results in decreased expression of HIRIP3 mRNAdecreases expression 17951470
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.6617505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8814692618
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.0211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8915885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.7910977129
MESH:D002779 Cholestasis Ethinyl Estradiol 3.1716105132 11677210 17681005 17110522 16919318 17333356 15861022
MESH:D003092 Colitis Selenium 4.3417936198
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.1015619225 19416960 19420014 17522070 12392966 16177239 18713872 19085960 2444490 16081117 14550746 10915739 19923254 12958197 10774834 17906064 12594235 15968718 11743745 14986274 12153990 16781746 12540782 16109766 16393943 11834606 19370779 11421492 11529661 11287661 17562736 12705907 16485898 19739265 11739529 11461765 10663392 14725611 19164858 18071297 16227642
MESH:D056486 Drug-Induced Liver Injury Selenium 4.1015131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.6912538720
MESH:D005234 Fatty Liver Ethinyl Estradiol 3.2415345470
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D006333 Heart Failure Selenium 3.2917162251
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D007021 Hypospadias Ethinyl Estradiol 4.3716569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7317937319
MESH:D007251 Influenza, Human Selenium 4.9216624496
MESH:D007674 Kidney Diseases Acetaminophen 2.4012587719 15629191
MESH:D007676 Kidney Failure, Chronic Selenium 4.3116518626
MESH:D008107 Liver Diseases Acetaminophen 1.7011587558 19014921 16610002 12969438 16611625 19784758 12587719 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6316871587 17185352
MESH:D008325 Mammary Neoplasms, Experimental Selenium 2.9915318939
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D008654 Mesothelioma Selenium 2.9215107826
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2118514411
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.1511578682
MESH:D010954 Plasmacytoma Selenium 5.6115087411
MESH:D011537 Pruritus Ethinyl Estradiol 3.9416919318 15861022
MESH:D013088 Spermatocele Ethinyl Estradiol 4.6616709447
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.0811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5215669648
MESH:D014581 Urticaria Acetaminophen 3.4410982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8014692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.9714671159 15869587
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018