AutismKB 2.0

Annotation Detail for GALR3


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Basic Information Top
Gene Symbol:GALR3 ( - )
Gene Full Name: galanin receptor 3
Band: 22q13.1
Quick LinksEntrez ID:8484; OMIM: 603692; Uniprot ID:GALR3_HUMAN; ENSEMBL ID: ENSG00000128310; HGNC ID: 4134
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04080Neuroactive ligand-receptor interaction
Pathway IDPathway Name
Signaling by GPCR
No data
No data
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
CHEMDEPENDENCY
alcoholism
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of GALR3 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GALR3 mRNAaffects expression 16483693
D018038 Sodium Selenite Sodium Selenite results in increased expression of GALR3 mRNAincreases expression 18175754
D014810 Vitamin E Vitamin E results in increased expression of GALR3 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.1918287403
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.4916050911
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.7910977129
MESH:D019457 Chromosome Breakage Sodium Selenite 5.3115894690
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9319769572
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.1516285004
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.1411421492 12392966 16177239 17562736 19085960 19420014 15968718 16485898 17906064 11743745 12958197 2444490 16109766 11529661 19739265 16393943 11461765 11739529 17522070 19923254 16781746 12594235 14725611 10774834 19416960 12153990 16081117 15619225 18071297 14986274 12705907 11834606 11287661 14550746 10915739 10663392 19164858 12540782 19370779 18713872 16227642
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 4.1415131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:C538011 Eales disease Vitamin E 5.439068938
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D006330 Heart Defects, Congenital Vitamin E 3.1716080930
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.8116490937 16863852
MESH:D019584 Hot Flashes Vitamin E 4.6914716179
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D007251 Influenza, Human Vitamin E 4.9416624496
MESH:D007333 Insulin Resistance Sodium Selenite 3.5214714311
MESH:D007674 Kidney Diseases Acetaminophen 6.6512587719 15629191
MESH:D007674 Kidney Diseases Vitamin E 6.6512488133
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 1.9116169303
MESH:D008107 Liver Diseases Acetaminophen 1.7019014921 16611625 19784758 12969438 19460945 16610002 12587719 11587558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6316871587 17185352
MESH:D008171 Lung Diseases Vitamin E 3.4316863852
MESH:D008175 Lung Neoplasms Vitamin E 1.9011062179
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.5214737004
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2118514411
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.2618760546
MESH:D011471 Prostatic Neoplasms Vitamin E 3.2615084515
MESH:D012871 Skin Diseases Vitamin E 2.5218709164
MESH:D020521 Stroke Vitamin E 3.8416517955
MESH:D014581 Urticaria Acetaminophen 3.4410982225
Pathway ID Pathway Name
KEGG:04080 Neuroactive ligand-receptor interaction
REACT:14797 Signaling by GPCR
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28547
    • No data
    Releated disease ID Related disease Name
    PA446879Alcohol-Related Disorders
    PA443309Alcoholism
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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