AutismKB 2.0

Annotation Detail for MINA


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Basic Information Top
Gene Symbol:MINA ( DKFZp762O1912,FLJ14393,MDIG,MINA53,NO52 )
Gene Full Name: MYC induced nuclear antigen
Band: 3q11.2
Quick LinksEntrez ID:84864; OMIM: 612049; Uniprot ID:MINA_HUMAN; ENSEMBL ID: ENSG00000170854; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
200045Validated targets of C-MYC transcriptional activation
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of MINA mRNAaffects expression 21346803
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of MINA mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of MINA mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of MINA mRNAaffects expression 16483693
D016572 Cyclosporine Cyclosporine results in increased expression of MINA mRNAincreases expression 20106945
D012822 Silicon Dioxide Silicon Dioxide results in increased expression of MINA mRNAincreases expression 15897898
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 4.417525203
MESH:D000138 Acidosis Ammonium Chloride 4.0218287403
MESH:D000799 Angioedema Acetaminophen 4.3610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 2.9316705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.933084413
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 7.9814694615
MESH:D002386 Cataract Acetaminophen 7.9810977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.7312371664
MESH:D002779 Cholestasis Cyclosporine 3.1419486331
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 4.4515095906
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.4318551238
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 6.7118551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 6.7121346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.7119164858 15968718 19923254 19416960 10915739 16109766 19370779 19739265 14550746 16227642 16393943 19085960 12153990 11834606 12540782 14986274 10774834 16177239 15619225 12958197 12594235 16081117 19420014 16781746 2444490 11421492 10663392 14725611 17562736 11461765 18713872 17522070 11739529 12705907 11287661 18071297 11743745 12392966 11529661 16485898 17906064
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.6219426721
MESH:D005234 Fatty Liver Cyclosporine 3.1819224547
MESH:D005355 Fibrosis Cyclosporine 3.5612639820 12168785
MESH:D005756 Gastritis Acetaminophen 4.1916983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.688708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.8815720958
MESH:D006930 Hyperalgesia Acetaminophen 2.9516870215
MESH:D006973 Hypertension Cyclosporine 2.1910903974
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.9615604871
MESH:D007674 Kidney Diseases Acetaminophen 6.3415629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 6.348314463 10903974 18776723
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 8.1816705839
MESH:D007680 Kidney Neoplasms Cyclosporine 8.1812371664
MESH:D008107 Liver Diseases Acetaminophen 1.6916611625 12969438 16610002 19460945 19784758 19014921 11587558 12587719
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5417185352 16871587
MESH:D008175 Lung Neoplasms marker/mechanism 15897898
MESH:D008180 Lupus Erythematosus, Systemic Silicon Dioxide 4.5516373255
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9819513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.3116801185
MESH:D009336 Necrosis 2,4-dinitrotoluene 4.3218551238
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.9617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5719348381 18481113
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1418514411
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 10.1612819281 16049721
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 10.1614694615
MESH:D010146 Pain Acetaminophen 2.6516870215
MESH:D011230 Precancerous Conditions Cyclosporine 3.5112371664
MESH:D011565 Psoriasis Cyclosporine 2.3116882103
MESH:D011658 Pulmonary Fibrosis Silicon Dioxide 4.7114975940 17365031 12193738
MESH:D012640 Seizures 2,4-dinitrotoluene 2.7318551238
MESH:D012829 Silicosis Silicon Dioxide 7.7318666137
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 2.3816049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.7810091137
MESH:D014581 Urticaria Acetaminophen 3.3310982225
MESH:D014605 Uveitis Cyclosporine 4.501336536
MESH:D014985 Xerophthalmia Cyclosporine 4.9617120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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