AutismKB 2.0

Annotation Detail for PARP10


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Basic Information Top
Gene Symbol:PARP10 ( FLJ14464 )
Gene Full Name: poly (ADP-ribose) polymerase family, member 10
Band: 8q24.3
Quick LinksEntrez ID:84875; OMIM: 609564; Uniprot ID:PAR10_HUMAN; ENSEMBL ID: ENSG00000178685; HGNC ID: 25895
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D001151 Arsenic Arsenic affects the expression of PARP10 mRNAaffects expression 18414638
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of PARP10 mRNAincreases expression 20382639
D018038 Sodium Selenite Sodium Selenite results in increased expression of PARP10 mRNAincreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D018246 Adrenocortical Adenoma Arsenic 6.0817306315
MESH:D020261 Arsenic Poisoning Arsenic 2.9616251483 12569548 16835338 18414634
MESH:D050197 Atherosclerosis Arsenic 3.4819371607 12928151
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.8017687452 15504454
MESH:D006528 Carcinoma, Hepatocellular Arsenic 2.3216507464 17306315
MESH:D002294 Carcinoma, Squamous Cell Arsenic 2.7817687452 15504454 18922899
MESH:D002295 Carcinoma, Transitional Cell Arsenic 4.5218640142
MESH:D002318 Cardiovascular Diseases Arsenic 3.7415738583 17938729 19152805
MESH:D002340 Carotid Artery Diseases Arsenic 4.7316973168 18022660
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0120889678
MESH:D019457 Chromosome Breakage Sodium Selenite 5.4115894690
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.1916285004
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 2.3715131321
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1520426865
MESH:D005534 Foot Diseases Arsenic 6.436392382
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.9017050553
MESH:D006973 Hypertension Arsenic 3.0016076760 11953799 9931084
MESH:D006987 Hypesthesia Arsenic 6.4316093927
MESH:D007333 Insulin Resistance Sodium Selenite 3.5414714311
MESH:D007642 Keratosis Arsenic 5.7316930632 12749816
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 3.8217339181
MESH:D008107 Liver Diseases Arsenic 2.6211134558
MESH:D008113 Liver Neoplasms Arsenic 2.8016368122
MESH:D008175 Lung Neoplasms Arsenic 2.2119168569 17976673 17306315
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.5914737004
MESH:D017202 Myocardial Ischemia Arsenic 4.3515371236
MESH:D009436 Neural Tube Defects Arsenic 3.7216620997
MESH:D020078 Neurogenic Inflammation Arsenic 4.9017056641
MESH:D010051 Ovarian Neoplasms Arsenic 2.8517306315
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.7616093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 5.7316905509 6392382 15371236
MESH:D011471 Prostatic Neoplasms Arsenic 3.3716140617
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.3718760546
MESH:D011507 Proteinuria Arsenic 4.5321343184
MESH:D012871 Skin Diseases Arsenic 2.8317548696 15952646 18709164 19834688 16759981 6392382 16702368 17938729 17453740 17050553 16353154
MESH:D012878 Skin Neoplasms Arsenic 3.1817976673 16251483 17029826 17050553 15504454 19538983
MESH:D001749 Urinary Bladder Neoplasms Arsenic 2.9518640142 15987713 19429237 17306315 17976673 19322015 11144890
MESH:D014652 Vascular Diseases Arsenic 5.4817056641
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018