AutismKB 2.0

Annotation Detail for ATAD1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ATAD1 ( AFDC1,FLJ14600 )
Gene Full Name: ATPase family, AAA domain containing 1
Band: 10q23.31
Quick LinksEntrez ID:84896; OMIM: NA; Uniprot ID:ATAD1_HUMAN; ENSEMBL ID: ENSG00000138138; HGNC ID: 25903
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C014211 2,3,7,8-tetrachlorodibenzofuran 2,3,7,8-tetrachlorodibenzofuran affects the expression of ATAD1 mRNAaffects expression 18343893
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of ATAD1 mRNAaffects expression 21346803
C035208 2-amino-4,6-dinitrotoluene 2-amino-4,6-dinitrotoluene affects the expression of ATAD1 mRNAaffects expression 21346803
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of ATAD1 mRNAaffects expression 21346803
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of ATAD1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ATAD1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin affects the expression of ATAD1 mRNAaffects expression 18343893
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ATAD1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of ATAD1 mRNAincreases expression 15328365
C066340 tolcapone tolcapone binds to ATAD1 proteinaffects binding 19783845
D014303 Trinitrotoluene Trinitrotoluene affects the expression of ATAD1 mRNAaffects expression 21346803
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 2-amino-4,6-dinitrotoluene 23.527525203
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 23.527525203
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 23.5214514962 11752688 15322242
MESH:D000014 Abnormalities, Drug-Induced Trinitrotoluene 23.527525203
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.3217505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8614692618
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.7116835633
MESH:D017109 Akathisia, Drug-Induced tolcapone 6.6711080934
MESH:D000544 Alzheimer Disease tolcapone 3.3220150427
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.1711748828
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.7711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8015885639
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.2912125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.1715340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.9115746008
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.6820435547
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.9916835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 1.7816705839
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4918850075 18670907 16120746
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 8.3314694615
MESH:D002386 Cataract Trinitrotoluene 8.3314694615 15817613
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.3816835633
MESH:D002779 Cholestasis Ethinyl Estradiol 3.0515861022 16919318 11677210 16105132 17333356 17681005 17110522
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.198697196 15668235 16354765 12621046 15340226
MESH:D000013 Congenital Abnormalities 2-amino-4,6-dinitrotoluene 24.1115095906
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 24.1115095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 24.1114669216 17141729
MESH:D000013 Congenital Abnormalities Trinitrotoluene 24.1115095906
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2610048152 20055451 15322242
MESH:D003490 Cyanosis 2,4-dinitrotoluene 12.2718551238
MESH:D003490 Cyanosis Trinitrotoluene 12.2718551238
MESH:D003866 Depressive Disorder tolcapone 4.4711224284 7768276
MESH:D003865 Depressive Disorder, Major tolcapone 5.1210440460
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7117107852
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 16.1218551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2-amino-4,6-dinitrotoluene 16.1221346803
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 16.1221346803
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 16.1220420201
MESH:D056486 Drug-Induced Liver Injury tolcapone 16.1216604736 19783845
MESH:D056486 Drug-Induced Liver Injury Trinitrotoluene 16.1221346803 18551238
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.9311462148
MESH:D004409 Dyskinesia, Drug-Induced tolcapone 5.7711455177
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.6111000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.2818230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.4712538720
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.259294722 10568697
MESH:D054908 Extensively Drug-Resistant Tuberculosis tolcapone 6.3219578428
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.1911564622
MESH:D005234 Fatty Liver Ethinyl Estradiol 3.0515345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.7611858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.2520067830
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.9710696789
MESH:D006330 Heart Defects, Congenital 2,3,7,8-tetrachlorodibenzofuran 7.3611294989
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 7.3611294989 10048152
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.5811000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 9.7615340226 12621046 16120746
MESH:D006529 Hepatomegaly Trinitrotoluene 9.7615817613
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.4215340226 18606429 16959395 16354765 8697196
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9818670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 4.1216945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.7212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 7.4117937319
MESH:D007248 Infertility, Male Trinitrotoluene 7.4112150543
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.9612878042 12200463
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.5816580747
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 3.1716705839
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 1.2412878042
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 1.7916984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.2412151625
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 1.2419555203 11884234
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.2112213967
MESH:D009336 Necrosis 2,4-dinitrotoluene 11.8318551238
MESH:D009336 Necrosis Trinitrotoluene 11.8318551238
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.4914600291
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 16.6512819281 16049721
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 16.6514694615
MESH:D009784 Occupational Diseases Trinitrotoluene 16.6512819281 14694615 17852074
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.9511578682
MESH:D010300 Parkinson Disease tolcapone 3.6710651109 19578428 7566641 1977408 20334432 11746615 11586115 20216409 9754991 8635184 19783845 9333106 8739811 11432539 18328768 17089403 16758261 11793426 9708959 9305320 9591521
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.6212520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.8418163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.5311222880 11896295 11399792 11118676
MESH:D011537 Pruritus Ethinyl Estradiol 3.6515861022 16919318
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.1218990726
MESH:D012640 Seizures 2,4-dinitrotoluene 6.7318551238
MESH:D012640 Seizures Trinitrotoluene 6.7318551238
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.1416192470
MESH:D013088 Spermatocele Ethinyl Estradiol 4.3216709447
MESH:D013163 Splenomegaly Trinitrotoluene 5.5115817613
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.8811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.3715669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.2812697716
MESH:D018088 Tuberculosis, Multidrug-Resistant tolcapone 6.3219578428
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 2.3616049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.6510091137
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.5814692618
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.9712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.7815869587 14671159
MESH:D014820 Vitiligo tolcapone 5.4710573327
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.6215886252
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved