AutismKB 2.0

Annotation Detail for MICALCL


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Basic Information Top
Gene Symbol:MICALCL ( Ebitein1,FLJ14966 )
Gene Full Name: MICAL C-terminal like
Band: 11p15.3
Quick LinksEntrez ID:84953; OMIM: 612355; Uniprot ID:MICLK_HUMAN; ENSEMBL ID: ENSG00000133808; HGNC ID: 25933
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of MICALCL mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of MICALCL mRNAaffects expression 16483693
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of MICALCL mRNAaffects expression 17484886
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in decreased expression of MICALCL mRNAdecreases expression 17616710
D018038 Sodium Selenite Sodium Selenite results in decreased expression of MICALCL mRNAdecreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.1018287403
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.2615721981 16097048 18705752 16124888 15673190 16192424 15700767 16011737 16227642 10355542 3786805 16050911
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 3.1116705839
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 3.1118788625
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.006135515
MESH:D019457 Chromosome Breakage Sodium Selenite 5.2415894690
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.5018551238
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.1016285004
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 6.7821346803 18551238
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 6.7821278145 19336974 19085960 3732212 2869522 15968718 10092053 6623471 9327722 15998439 16227642 7179309 10915739 7120509 6884620 3786805 16177239 15027814 7440962 11566570 17522070 4309450
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 6.7815131321
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 2.8415623463 15547733 15150132 15878914 15547721 16704527 16805852 16510608 15264214
MESH:D005234 Fatty Liver Carbon Tetrachloride 3.5461145 15959796 12795759 16045604 12631006 19224547 17595544 16239168
MESH:D005355 Fibrosis Carbon Tetrachloride 3.9418705752
MESH:D006505 Hepatitis Carbon Tetrachloride 4.0319110552 19900420
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 5.0716899240
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.5715338365
MESH:D007333 Insulin Resistance Sodium Selenite 3.4914714311
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.2816705839
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.9811408273 17157831 16943688 17174718 11903743 16239168 16221502 21278145 17334410
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 1.7518705752 17640975 16011737 15818738 12609069 14620537 18205269 18418968 11481614 18156304 16033810 15876570 18339082 16248980 14716833 18376398 18187930 17714472 17900296 17869086 15362042 18006644 18429990 18210741 18166357 18395914 18481824 17481882 12632512 12667390 16192424 17922224 16116963 12649538 18317297 16136751 15931870 15673190 17976157 12632514 17944888 18251166 15959796 14716496 18263696 15730626 15052691 14748882 15996030 12445421 15057751 13678700 17565644 18472094 15893842 18277467 16097048 12546737 15650968 12445418 17631135 12666154 16027843 14512876 18420326 18054572 17721639 17823541 12586293 17557913 10355542 16638106 12741479 12898905 14724832 15370692 18395095 17805973 18279442 17525996 20821823 15338365 15123356 17698563 12958196 17708605 17766677 17761835 18412020 18472332 12389079 15925388 16015684
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.1515720792 15830285 17285989 16964402 16246199
MESH:D017093 Liver Failure Carbon Tetrachloride 4.6515123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 4.0416899240 14706259
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 4.927678174
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 4.9219294768
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 6.612876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 6.6112014681 15583823
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.4614737004
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.407678174 18551238
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.7816049721
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.3418760546
MESH:D012640 Seizures 2,6-dinitrotoluene 2.7618551238
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 2.3312958204 17575124
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.4016049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.8610091137
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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