AutismKB 2.0

Annotation Detail for ALKBH6


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Basic Information Top
Gene Symbol:ALKBH6 ( ABH6,MGC15677 )
Gene Full Name: alkB, alkylation repair homolog 6 (E. coli)
Band: 19q13.12
Quick LinksEntrez ID:84964; OMIM: 613304; Uniprot ID:ALKB6_HUMAN; ENSEMBL ID: ENSG00000181392,ENSG00000239382; HGNC ID: 28243
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of ALKBH6 mRNAaffects expression 17562736
D018038 Sodium Selenite Sodium Selenite results in increased expression of ALKBH6 mRNAincreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.9110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8310977129
MESH:D019457 Chromosome Breakage Sodium Selenite 5.5215894690
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.2516285004
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.1911421492 19164858 17562736 10774834 19370779 12594235 2444490 11739529 12958197 11743745 16081117 18713872 19923254 10663392 16485898 12392966 16393943 19420014 17522070 15619225 15968718 14550746 19085960 12705907 16109766 11287661 16177239 14986274 10915739 16781746 18071297 12540782 19739265 11461765 11529661 16227642 14725611 12153990 19416960 11834606 17906064
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 4.1915131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.1719426721
MESH:D005756 Gastritis Acetaminophen 4.7416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1116870215
MESH:D007333 Insulin Resistance Sodium Selenite 3.5714714311
MESH:D007674 Kidney Diseases Acetaminophen 2.4412587719 15629191
MESH:D008107 Liver Diseases Acetaminophen 1.7111587558 19784758 16610002 19014921 12587719 19460945 16611625 12969438
MESH:D017114 Liver Failure, Acute Acetaminophen 3.7417185352 16871587
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.6614737004
MESH:D008546 Melanoma, Experimental Acetaminophen 4.3319513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3118514411
MESH:D010146 Pain Acetaminophen 2.8216870215
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.3218760546
MESH:D014581 Urticaria Acetaminophen 3.5810982225
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018