Annotation Detail for TOX2
Basic Information
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| Gene Symbol: | TOX2 ( C20orf100,GCX-1,MGC15880,dJ1108D11.2,dJ495O3.1 ) |
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| Gene Full Name: | TOX high mobility group box family member 2 |
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| Band: | 20q13.12 |
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| Quick Links | Entrez ID:84969; OMIM: 611163; Uniprot ID:TOX2_HUMAN; ENSEMBL ID: ENSG00000124191; HGNC ID: 16095 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TOX2 mRNA | decreases expression | 20382639
19150397
|
| D017632 |
Asbestos, Serpentine |
Asbestos, Serpentine results in increased expression of TOX2 mRNA | increases expression | 16251409
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D001195 |
Asbestosis |
|
Asbestos, Serpentine |
6.35 | 10751356 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
3.04 | 20889678 |
| MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.16 | 20426865 |
| MESH:D008171 |
Lung Diseases |
|
Asbestos, Serpentine |
4.66 | 17200189 |
| MESH:D008175 |
Lung Neoplasms |
|
Asbestos, Serpentine |
3.08 | 11198217 |
| MESH:D009374 |
Neoplasms, Experimental |
|
Asbestos, Serpentine |
5.61 | 11704859 |
| MESH:D010995 |
Pleural Diseases |
|
Asbestos, Serpentine |
6.46 | 10923243 |
| MESH:D011658 |
Pulmonary Fibrosis |
|
Asbestos, Serpentine |
3.97 | 18569384 15511213 |
Related Pathway Information