Annotation Detail for PPFIA4
Basic Information
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| Gene Symbol: | PPFIA4 ( - ) |
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| Gene Full Name: | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
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| Band: | 1q32.1 |
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| Quick Links | Entrez ID:8497; OMIM: 603145; Uniprot ID:LIPA4_HUMAN; ENSEMBL ID: ENSG00000143847; HGNC ID: 9248 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene affects the expression of PPFIA4 mRNA | affects expression | 21346803
|
| D000643 |
Ammonium Chloride |
Ammonium Chloride affects the expression of PPFIA4 mRNA | affects expression | 16483693
|
| D003035 |
Cobalt |
[tungsten carbide binds to Cobalt] which results in increased expression of PPFIA4 mRNA | affects binding|increases expression | 20105288
|
| C018021 |
cobaltous chloride |
cobaltous chloride results in increased expression of PPFIA4 mRNA | increases expression | 20105288
|
| D005419 |
Flavonoids |
Flavonoids results in decreased expression of PPFIA4 mRNA | decreases expression | 18035473
|
| C056507 |
gemcitabine |
gemcitabine results in increased expression of PPFIA4 mRNA | increases expression | 17039268
|
| C002802 |
tungsten carbide |
[tungsten carbide binds to Cobalt] which results in increased expression of PPFIA4 mRNA | affects binding|increases expression | 20105288
|
| C002802 |
tungsten carbide |
tungsten carbide results in increased expression of PPFIA4 mRNA | increases expression | 20105288
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
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| MESH:D000138 |
Acidosis |
|
Ammonium Chloride |
3.95 | 18287403 |
| MESH:D001943 |
Breast Neoplasms |
|
Cobalt |
3.09 | 15986119 |
| MESH:D001943 |
Breast Neoplasms |
|
gemcitabine |
3.09 | 17039268 18382427 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
1.78 | 16705839 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
2.95 | 6135515 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
4.38 | 18551238 |
| MESH:D017449 |
Dermatitis, Allergic Contact |
|
cobaltous chloride |
4.38 | 11298694 15059100 16823706 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
2.03 | 18551238 21346803 |
| MESH:D006973 |
Hypertension |
|
Cobalt |
3.99 | 17039479 |
| MESH:D007249 |
Inflammation |
|
Flavonoids |
2.77 | 17296493 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
3.21 | 16705839 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
2.23 | 7678174 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.70 | 2876786 6135515 2876784 |
| MESH:D008173 |
Lung Diseases, Obstructive |
|
Cobalt |
6.22 | 6434250 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
4.26 | 18551238 7678174 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
3.70 | 16049721 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
gemcitabine |
3.61 | 11504793 17440100 18992248 16929163 18383843 |
| MESH:D011658 |
Pulmonary Fibrosis |
|
Cobalt |
4.08 | 6434250 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
2.71 | 18551238 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
2.38 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
4.71 | 10091137 |
Related Pathway Information