AutismKB 2.0

Annotation Detail for FAM83A


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Basic Information Top
Gene Symbol:FAM83A ( BJ-TSA-9,MGC14128 )
Gene Full Name: family with sequence similarity 83, member A
Band: 8q24.13
Quick LinksEntrez ID:84985; OMIM: NA; Uniprot ID:FA83A_HUMAN; ENSEMBL ID: ENSG00000147689; HGNC ID: 28210
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
C015001 arsenite arsenite results in decreased expression of FAM83A mRNAdecreases expression 19716837
C015001 arsenite arsenite results in increased methylation of FAM83A promoterincreases methylation 19716837
C014347 decitabine [decitabine co-treated with trichostatin A] inhibits the reaction [sodium arsenite affects the methylation of FAM83A promoter]affects cotreatment|affects methylation|decreases reaction 18448484
C014347 decitabine decitabine inhibits the reaction [sodium arsenite affects the methylation of FAM83A promoter]affects methylation|decreases reaction 18448484
C406082 monomethylarsonous acid [monomethylarsonous acid affects the acetylation of HIST3H3 protein] which affects the methylation of FAM83A promoteraffects acetylation|affects methylation 18448484
C406082 monomethylarsonous acid monomethylarsonous acid results in decreased expression of FAM83A mRNAdecreases expression 19716837
18448484
C406082 monomethylarsonous acid monomethylarsonous acid results in increased methylation of FAM83A promoterincreases methylation 19716837
C017947 sodium arsenite [decitabine co-treated with trichostatin A] inhibits the reaction [sodium arsenite affects the methylation of FAM83A promoter]affects cotreatment|affects methylation|decreases reaction 18448484
C017947 sodium arsenite decitabine inhibits the reaction [sodium arsenite affects the methylation of FAM83A promoter]affects methylation|decreases reaction 18448484
C017947 sodium arsenite [sodium arsenite affects the acetylation of HIST3H3 protein] which affects the methylation of FAM83A promoteraffects acetylation|affects methylation 18448484
C017947 sodium arsenite sodium arsenite results in decreased expression of FAM83A mRNAdecreases expression 18448484
C012589 trichostatin A [decitabine co-treated with trichostatin A] inhibits the reaction [sodium arsenite affects the methylation of FAM83A promoter]affects cotreatment|affects methylation|decreases reaction 18448484
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 5.3115276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 5.5116712894 17306315
MESH:D001943 Breast Neoplasms decitabine 2.5419208741 18320071
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 2.0016507464 17306315 15276417
MESH:D002294 Carcinoma, Squamous Cell decitabine 5.0819215824
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 5.0818572023
MESH:D002471 Cell Transformation, Neoplastic monomethylarsonous acid 7.9619716837
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 7.9620056578 19524636
MESH:D003110 Colonic Neoplasms arsenite 4.1715037631
MESH:D003110 Colonic Neoplasms decitabine 4.1717616700
MESH:D015179 Colorectal Neoplasms decitabine 2.1018981723
MESH:D004701 Endocrine Gland Neoplasms decitabine 16.1619294695
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 16.1619294695
MESH:D005234 Fatty Liver arsenite 4.1518296743
MESH:D005355 Fibrosis arsenite 4.5518296743
MESH:D005833 Genital Neoplasms, Female sodium arsenite 5.2216452187
MESH:D005909 Glioblastoma trichostatin A 4.0518801729
MESH:D006258 Head and Neck Neoplasms decitabine 3.7119215824
MESH:D006689 Hodgkin Disease sodium arsenite 3.4712676792
MESH:D007248 Infertility, Male decitabine 7.6617581917
MESH:D007248 Infertility, Male sodium arsenite 7.6615346721 12646999
MESH:D007674 Kidney Diseases sodium arsenite 2.9820008137
MESH:D007938 Leukemia decitabine 3.2219235587 18980019
MESH:D007951 Leukemia, Myeloid decitabine 4.3719117987 18454857 17236224
MESH:D015470 Leukemia, Myeloid, Acute decitabine 4.4418206229 19010910 18704418 18460780 19387464 17679729
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 4.4418206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 6.0718055864
MESH:D008103 Liver Cirrhosis arsenite 3.5918296743
MESH:D008113 Liver Neoplasms sodium arsenite 2.4716712894 15276417
MESH:D008171 Lung Diseases sodium arsenite 3.4019095001
MESH:D008175 Lung Neoplasms arsenite 2.8016809336
MESH:D008175 Lung Neoplasms sodium arsenite 2.8016712894 17077188 17306315 19931552 15276417
MESH:D008223 Lymphoma decitabine 3.6619470736
MESH:D008545 Melanoma decitabine 5.5516505122 17785578
MESH:D008545 Melanoma sodium arsenite 5.5516487513 19082730
MESH:D008545 Melanoma trichostatin A 5.5516505122
MESH:D009101 Multiple Myeloma decitabine 8.4918172295
MESH:D009101 Multiple Myeloma trichostatin A 8.4918172295
MESH:D009190 Myelodysplastic Syndromes decitabine 3.5618608210 19157545 16882708 19010910
MESH:D009369 Neoplasms decitabine 5.7317925555 19116145 19470736
MESH:D009369 Neoplasms sodium arsenite 5.7311559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 4.1520056578
MESH:D009389 Neovascularization, Pathologic arsenite 4.9515738583
MESH:D009436 Neural Tube Defects sodium arsenite 3.3612854658
MESH:D010051 Ovarian Neoplasms decitabine 8.5719331143 19259094
MESH:D010051 Ovarian Neoplasms sodium arsenite 8.5717306315 15276417
MESH:D010051 Ovarian Neoplasms trichostatin A 8.5719331143
MESH:D010190 Pancreatic Neoplasms decitabine 6.0319294695
MESH:D010190 Pancreatic Neoplasms trichostatin A 6.0319294695
MESH:D055728 Primary Myelofibrosis decitabine 14.0917616702
MESH:D055728 Primary Myelofibrosis trichostatin A 14.0917616702
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.5016039940
MESH:D011471 Prostatic Neoplasms trichostatin A 3.5019789329 18798265
MESH:D012208 Rhabdomyosarcoma decitabine 4.8119155313
MESH:D012871 Skin Diseases monomethylarsonous acid 3.4517431481
MESH:D012878 Skin Neoplasms sodium arsenite 2.8418572023 19524636
MESH:D016135 Spinal Dysraphism sodium arsenite 4.0712854658
MESH:D013274 Stomach Neoplasms decitabine 2.1019037991
MESH:D013964 Thyroid Neoplasms decitabine 3.6017967635
MESH:D001749 Urinary Bladder Neoplasms decitabine 9.2017616700 19087683
MESH:D001749 Urinary Bladder Neoplasms monomethylarsonous acid 9.2020375083
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 9.2017306315 16452187 16712894 11723127
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 4.1111813266
MESH:D014604 Uveal Neoplasms decitabine 5.5217785578
MESH:D014652 Vascular Diseases sodium arsenite 4.9617056641
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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