Annotation Detail for USP45
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D008345 |
Manganese |
Manganese results in decreased expression of USP45 mRNA | decreases expression | 17175027
|
| C025340 |
manganese chloride |
manganese chloride results in decreased expression of USP45 mRNA | decreases expression | 17175027
|
| C006253 |
pirinixic acid |
pirinixic acid results in decreased expression of USP45 mRNA | decreases expression | 18445702
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.64 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.22 | 16434500 |
| MESH:D000756 |
Anemia, Sideroblastic |
|
Manganese |
12.69 | 16910769 |
| MESH:D000756 |
Anemia, Sideroblastic |
|
manganese chloride |
12.69 | 16910769 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.63 | 19483382 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.15 | 19176532 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.59 | 18249437 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.96 | 12083418 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.25 | 19236843 20131406 |
| MESH:D005909 |
Glioblastoma |
|
Manganese |
4.18 | 17043766 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.78 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.64 | 19176532 18467677 19772884 16221962 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.63 | 20558911 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.90 | 16306350 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.94 | 15890375 20007298 16377806 |
| MESH:D020149 |
Manganese Poisoning |
|
Manganese |
6.39 | 16568477 16551646 19453300 |
| MESH:D009069 |
Movement Disorders |
|
Manganese |
5.54 | 16551646 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.16 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.29 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.29 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.12 | 17405874 |
| MESH:D009410 |
Nerve Degeneration |
|
Manganese |
4.62 | 16551646 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.89 | 20558911 |
| MESH:D010300 |
Parkinson Disease |
|
Manganese |
3.50 | 11181820 |
| MESH:D020734 |
Parkinsonian Disorders |
|
Manganese |
4.92 | 16140633 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.56 | 19058328 |
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