AutismKB 2.0

Annotation Detail for HAT1


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Basic Information Top
Gene Symbol:HAT1 ( KAT1 )
Gene Full Name: histone acetyltransferase 1
Band: 2q31.1
Quick LinksEntrez ID:8520; OMIM: 603053; Uniprot ID:HAT1_HUMAN; ENSEMBL ID: ENSG00000128708; HGNC ID: 4821
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of HAT1 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of HAT1 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride results in increased expression of HAT1 proteinincreases expression 16483693
C026405 bromotriethylstannane bromotriethylstannane results in increased activity of HAT1 proteinincreases activity 15603928
C020735 dibutyldichlorotin dibutyldichlorotin results in increased activity of HAT1 proteinincreases activity 15603928
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of HAT1 mRNAincreases expression 17854601
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of HAT1 mRNA]decreases reaction|increases expression 17854601
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of HAT1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of HAT1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HAT1 mRNAaffects cotreatment|increases expression 17942748
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of HAT1 mRNAincreases expression 17616710
C006253 pirinixic acid pirinixic acid results in increased expression of HAT1 mRNAincreases expression 18301758
17950772
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of HAT1 mRNA]increases expression|increases reaction 17950772
C017947 sodium arsenite sodium arsenite results in increased expression of HAT1 mRNAincreases expression 19822182
D013629 Tamoxifen Tamoxifen affects the expression of HAT1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HAT1 mRNAaffects cotreatment|increases expression 17942748
D014212 Tretinoin Tretinoin results in decreased expression of HAT1 mRNAdecreases expression 16054129
C011559 tributyltin tributyltin results in increased activity of HAT1 proteinincreases activity 15603928
C012594 triphenyltin chloride triphenyltin chloride results in increased activity of HAT1 proteinincreases activity 15603928
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.6114745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.9015322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.6118287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0017505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.1518653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8214692618
MESH:D000236 Adenoma Diethylnitrosamine 2.876695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 17.5916434500 19052882 18056438 17620307 17162532 19061943
MESH:D018248 Adenoma, Liver Cell pirinixic acid 17.5916434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 17.5916835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.7615276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.9617306315 16712894
MESH:D000505 Alopecia Tretinoin 3.6415955085
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9711748828
MESH:D000799 Angioedema Acetaminophen 3.9110982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.2615885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.2616412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2716292516
MESH:D001249 Asthma Tretinoin 2.3516456186
MESH:D001321 Autistic Disorder Acetaminophen 1.4218445737
MESH:D001471 Barrett Esophagus Tretinoin 4.4416935849
MESH:D001778 Blood Coagulation Disorders pirinixic acid 15.4519483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 15.4512125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 15.4516206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7815746008
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.9317474063
MESH:D001943 Breast Neoplasms Tamoxifen 1.9319059307 19011961 19288272 19115204 19289846 19221464 20390343 15565566 20859285 18855134 17049068 18815881 16818667 18351453 19410462 18629630 19487384 17893378 20544844 19142967 19244106 19189210 18821012 19189212 18997820 16202921 17261762 15668708 16873071 19084267 18425577 20135344 21138602 19155303 16273361 11161223 19200415 19066611 20005174 17242785 21152245 18984771 17440819 19103187 20065188
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9320435547
MESH:D001943 Breast Neoplasms Tretinoin 1.9316873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.6416813970
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8216835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.5519066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.2216168501
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 11.4616705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.463084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 11.4618978308 16502159 16681979 16935385 20101231 17138121 20512989 19208518 18691550 19919837 19107877 18788625 20524982 17978847 16698587 16328049 11831363 18210153 16540662 19171122 18785209 20214788 19383236 19539802 18494052 16878318 18056438 20727157 17428255 3084413 10737359 19701751 16830150 18393292 17162532 16569478 20935162 20514400 16807293 17761372 18665156 17173139 19519916 17055752 20432363 18971187 19394651 19052882 20084675 16288022 19418558 10672840 16779866 18506893 21159647 19822196 19335982 20007298 3581430
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 11.4616507464 17306315 15276417
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.4616924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 11.461917145
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 4.7118572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.7116096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.6417572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3818850075 18670907 16120746
MESH:D002386 Cataract Acetaminophen 7.2810977129
MESH:D002386 Cataract Tretinoin 7.2817460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 11.336135515
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 11.337505956 17174075 21159647 2727394
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 11.3319524636 20056578
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.6416129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.4119052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.4116835633
MESH:D002779 Cholestasis Ethinyl Estradiol 7.8111677210 17681005 17110522 16105132 17333356 16919318 15861022
MESH:D002779 Cholestasis pirinixic acid 7.8119176532
MESH:D002822 Choriocarcinoma Tretinoin 5.2216461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.8016354765 8697196 15668235 15340226 12621046
MESH:D002972 Cleft Palate Tretinoin 5.809407595
MESH:D003092 Colitis Tretinoin 3.7517035595
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0817141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4520055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.459224671 10589399 9125849 14991402 9211117 16925845 9142499 17551590 8800419 9664655
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.0618551238
MESH:D003711 Demyelinating Diseases Tamoxifen 4.4019031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4418249437
MESH:D003921 Diabetes Mellitus, Experimental triphenyltin chloride 5.509202216
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.2420387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.2417107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.5019279558
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 9.0118551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 9.012444490 10915739 12540782 15968718 14550746 19085960 16393943 16781746 17562736 19416960 11743745 12705907 11739529 18071297 12594235 17522070 19370779 14725611 19923254 17906064 10774834 11421492 12392966 11461765 19164858 11287661 10663392 19739265 16485898 16177239 18713872 16227642 12153990 16109766 11529661 12958197 19420014 16081117 14986274 15619225 11834606
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 9.0119107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 9.0120420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1619426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7811462148
MESH:D004487 Edema pirinixic acid 6.6312083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.6311000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 12.1616714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 12.1618230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.0712538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 9.0719031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.5017893378 20544844 19155303 16202921
MESH:D016889 Endometrial Neoplasms Tretinoin 7.5016569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.0510568697 9294722
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.1816302075
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 2.7816510608 15623463 16704527 16805852 15264214 15150132 15878914 15547721 15547733
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.9011564622
MESH:D005124 Eye Abnormalities Tretinoin 8.909664655 16938888
MESH:D005234 Fatty Liver Diethylnitrosamine 19.0021071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 19.0015345470
MESH:D005234 Fatty Liver pirinixic acid 19.0020131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 19.0014986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2516709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5011858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.5814745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.2319069698
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.7620067830
MESH:D005355 Fibrosis Tretinoin 8.7617994277
MESH:D005756 Gastritis Acetaminophen 3.7416983495
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.7316452187
MESH:D005909 Glioblastoma Tretinoin 3.0217312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6610696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.2016096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.2216084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.5810048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 6.5814991402 9664655
MESH:D006333 Heart Failure pirinixic acid 2.5520558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3611000095
MESH:D006529 Hepatomegaly pirinixic acid 8.4016221962 18467677 19176532 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.4015340226 12621046 16120746
MESH:D006689 Hodgkin Disease sodium arsenite 3.1812676792
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.1118606429 15340226 16959395 8697196 16354765
MESH:D006930 Hyperalgesia Acetaminophen 7.7016870215
MESH:D006930 Hyperalgesia Tretinoin 7.7016870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.6116778211
MESH:D006943 Hyperglycemia pirinixic acid 3.2120558911
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9118670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8516945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.7017937319
MESH:D007248 Infertility, Male sodium arsenite 6.7012646999 15346721
MESH:D007249 Inflammation Diethylnitrosamine 8.3518785209
MESH:D007249 Inflammation Tamoxifen 8.3519457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 8.3512200463 12878042
MESH:D007333 Insulin Resistance pirinixic acid 2.6516306350
MESH:D007410 Intestinal Diseases Tretinoin 3.8117994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 10.0316580747
MESH:D007569 Jaw Abnormalities Tretinoin 10.0315992940 17551590
MESH:D007674 Kidney Diseases Acetaminophen 6.0112587719 15629191
MESH:D007674 Kidney Diseases sodium arsenite 6.0120008137
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 7.4616705839
MESH:D007680 Kidney Neoplasms Tamoxifen 7.4618625569
MESH:D007938 Leukemia Tretinoin 2.7817143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.7316482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0817596541 16294345 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.1712679006 17649720 16331271 17712046 16140955 16891316 15748426 17361223 16935935 17107899 19029980 16788101 17217047 17339181 16823087 19642359 17301526 19075265 17368321 19035177 17506722 9834237 19225113 16766008 17294898
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.339224671
MESH:D008064 Lipidoses Tamoxifen 3.1717567588 15342952
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.8418522880 18407596 18665156 19638242 20032147
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.9515474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.9518564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.9512878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 4.9516248980 18397230
MESH:D008107 Liver Diseases Acetaminophen 3.9319460945 16610002 19784758 12587719 12969438 11587558 16611625 19014921
MESH:D008107 Liver Diseases Diethylnitrosamine 3.9317034775
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2616871587 17185352
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 18.137678174
MESH:D008113 Liver Neoplasms Diethylnitrosamine 18.1319427195 18754104 19073162 20137499 21278145 18977376 21047994 18648771 16942905 19499222 19426721 20452335 15885732 19294768 20583210 12771043 20118626 19090486 2422723 18644402 9163691 12112319 19833225 15175105 20434301 20101389 19996281 19638242 19256749 19812893 18978307 19254457 19850985 19690152 19255062 20501860 21071580 10737359 20492335 21167192 19642983 19551842 20405173 2862719
MESH:D008113 Liver Neoplasms pirinixic acid 18.1320007298 16377806 15890375
MESH:D008113 Liver Neoplasms sodium arsenite 18.1316712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 18.1316684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 18.1316984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 9.892876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 9.8917174075 16267830 16842330 19539802 18282651 18775883 18093689 18079962 18164116 18544905 19519916 19009564 18253720 3124819 2563599 19126423 18308698 21159647 17854601 17942915 9362446 19004024
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.8912151625
MESH:D008171 Lung Diseases sodium arsenite 3.1919095001
MESH:D008175 Lung Neoplasms Diethylnitrosamine 4.8620970405 6695378 20512841 21163286
MESH:D008175 Lung Neoplasms sodium arsenite 4.8617306315 19931552 16712894 17077188 15276417
MESH:D008175 Lung Neoplasms Tamoxifen 4.8618625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.8619555203 11884234
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.8119428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.6411731420 16827153 14580682 19196723 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 4.6119453300
MESH:D008527 Medulloblastoma Tretinoin 2.7917453147
MESH:D008545 Melanoma sodium arsenite 5.1219082730 16487513
MESH:D008545 Melanoma Tamoxifen 5.1212393984 19393235
MESH:D008545 Melanoma Tretinoin 5.1216752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.2315990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.6119513568
MESH:D008591 Meningomyelocele Tretinoin 4.4716940565
MESH:D009135 Muscular Diseases pirinixic acid 3.5516239165
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.0917596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.1519151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0412213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.9716411023
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.917678174 18551238
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.769029167 3581430
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.7619393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5219410462
MESH:D009369 Neoplasms pirinixic acid 8.3117405874
MESH:D009369 Neoplasms sodium arsenite 8.3111559025
MESH:D009369 Neoplasms Tretinoin 8.3116594593 16946489
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.7120056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.0619189210 19196722 19200415
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.6314600291
MESH:D009421 Nervous System Malformations Tretinoin 9.639125849
MESH:D009436 Neural Tube Defects sodium arsenite 7.3712854658
MESH:D009436 Neural Tube Defects Tretinoin 7.379142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.2618514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 8.2620387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.1820387270
MESH:D009765 Obesity pirinixic acid 1.8220558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.4616049721
MESH:D010051 Ovarian Neoplasms sodium arsenite 4.9117306315 15276417
MESH:D010051 Ovarian Neoplasms Tretinoin 4.9116936753
MESH:D010146 Pain Acetaminophen 6.6616870215
MESH:D010146 Pain Tretinoin 6.6616870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.2816540662
MESH:D010190 Pancreatic Neoplasms Tretinoin 5.2815976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7211578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3112520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5918163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.582563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2411118676 11896295 11399792 11222880
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.2516039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.2515067354
MESH:D011507 Proteinuria Tretinoin 3.6416636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.3615861022 16919318
MESH:D011625 Pterygium Tretinoin 4.8416723453
MESH:D015427 Reperfusion Injury pirinixic acid 2.4019058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8718990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.1316116481 16283617
MESH:D012640 Seizures 2,6-dinitrotoluene 2.5518551238
MESH:D012878 Skin Neoplasms sodium arsenite 9.5019524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.5016192470
MESH:D012878 Skin Neoplasms Tretinoin 9.5016467112
MESH:D013088 Spermatocele Ethinyl Estradiol 11.7716709447
MESH:D013088 Spermatocele Tamoxifen 11.7716709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.0919457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.8212854658
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.4418456281
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 3.4412958204 17575124
MESH:D013274 Stomach Neoplasms Tretinoin 3.4417261132
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9612697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 7.247505956
MESH:D013964 Thyroid Neoplasms Tretinoin 7.2416026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 3.8116051514
MESH:D014376 Tuberculosis Tretinoin 3.2416040207
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 8.3816049721
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 8.3811723127 16712894 16452187 17306315
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 8.3817572228 16712894 8653321
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.3710091137
MESH:D014581 Urticaria Acetaminophen 3.0110982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 9.5011813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 9.5016129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3314692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.6716752155
MESH:D014652 Vascular Diseases sodium arsenite 4.4717056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6612125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5714671159 15869587
MESH:D014820 Vitiligo Tretinoin 4.0916761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3115886252
MESH:D009396 Wilms Tumor Tretinoin 3.9916287080
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA29197
    • No data
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    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Releated drug ID Related drug Name
    PA450379mercaptopurine
    PA450428methotrexate
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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