AutismKB 2.0

Annotation Detail for CSDA


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CSDA ( CSDA1,DBPA,ZONAB )
Gene Full Name: cold shock domain protein A
Band: 12p13.1
Quick LinksEntrez ID:8531; OMIM: 603437; Uniprot ID:DBPA_HUMAN; ENSEMBL ID: ENSG00000060138; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of CSDA mRNAaffects expression 21346803
C027576 4-hydroxy-2-nonenal 4-hydroxy-2-nonenal results in decreased expression of CSDA mRNAdecreases expression 12419474
D000082 Acetaminophen Acetaminophen affects the expression of CSDA mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of CSDA proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CSDA mRNAaffects expression 16483693
C006780 bisphenol A bisphenol A results in decreased expression of CSDA mRNAdecreases expression 20678512
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of CSDA mRNAdecreases expression 12419474
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CSDA mRNAaffects cotreatment|decreases expression 20360939
D016572 Cyclosporine Cyclosporine results in increased expression of CSDA mRNAincreases expression 20106945
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CSDA mRNAaffects cotreatment|decreases expression 20360939
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of CSDA mRNAincreases expression 19638242
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of CSDA mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of CSDA mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CSDA mRNAaffects cotreatment|increases expression 17942748
D008713 Methimazole Methimazole results in decreased expression of CSDA mRNAdecreases expression 17403546
C494474 perchlorate perchlorate results in decreased expression of CSDA mRNAdecreases expression 17403546
C006253 pirinixic acid pirinixic acid results in increased expression of CSDA mRNAincreases expression 18301758
D011441 Propylthiouracil Propylthiouracil results in decreased expression of CSDA mRNAdecreases expression 17403546
D020849 Raloxifene Raloxifene affects the expression of CSDA mRNAaffects expression 16079270
D012643 Selenium Selenium results in increased expression of CSDA mRNAincreases expression 19244175
C017947 sodium arsenite sodium arsenite results in increased expression of CSDA mRNAincreases expression 12760830
D013629 Tamoxifen Tamoxifen affects the expression of CSDA mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CSDA mRNAaffects cotreatment|increases expression 17942748
C025643 vinclozolin vinclozolin affects the expression of CSDA mRNAaffects expression 19015723
D014810 Vitamin E Vitamin E results in decreased expression of CSDA mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.4214745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.7215322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.4318287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8117505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.9918653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.7814692618
MESH:D000236 Adenoma Diethylnitrosamine 2.786695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 16.5216434500 19052882 19061943 17620307 17162532 18056438
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.5216434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.5216835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.5715276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.7717306315 16712894
MESH:D000419 Albuminuria Raloxifene 4.4717308373 17451421
MESH:D000544 Alzheimer Disease Raloxifene 2.5115800139
MESH:D000690 Amyotrophic Lateral Sclerosis 4-hydroxy-2-nonenal 4.0210965797
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8311748828
MESH:D000799 Angioedema Acetaminophen 3.7110982225
MESH:D001008 Anxiety Disorders vinclozolin 3.5319015723
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.3311256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5815885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 14.6619483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 14.6619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 14.6612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6815746008
MESH:D001862 Bone Resorption bisphenol A 3.7411985600
MESH:D001930 Brain Injuries Raloxifene 4.3416580743
MESH:D001943 Breast Neoplasms bisphenol A 2.2917123778
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.2917474063
MESH:D001943 Breast Neoplasms Raloxifene 2.2915758505 17595753 17261762 17242785 17952589 17049068 15775269 17440819 17893378 16837676 16912660 15572757
MESH:D001943 Breast Neoplasms Tamoxifen 2.2919155303 19059307 20544844 16873071 19103187 17242785 18351453 20390343 19142967 16273361 20005174 18425577 20135344 19410462 19115204 21138602 18855134 18997820 18984771 18821012 19289846 17049068 15668708 17261762 11161223 19487384 18629630 20065188 15565566 19288272 16202921 19066611 19084267 16818667 17893378 19244106 18815881 19189212 19200415 17440819 19221464 20859285 21152245 19189210 19011961
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.2920435547
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.8016050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6916835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.3819066611
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 11.1116705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.113084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 11.1121507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 11.1116681979 20727157 19335982 19701751 18393292 16878318 17428255 18506893 3581430 19171122 19107877 17138121 18494052 16502159 18785209 19539802 19383236 17978847 19519916 20514400 10737359 16328049 19418558 17173139 19052882 16288022 16807293 3084413 17162532 18788625 20935162 17055752 21159647 19208518 20432363 10672840 18665156 16935385 18056438 16698587 18210153 16540662 20101231 20214788 19394651 18978308 18971187 16569478 11831363 16830150 18691550 19919837 17761372 19822196 20512989 16779866 20084675 20524982 20007298
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 11.1116507464 17306315 15276417
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.1116924424
MESH:D002278 Carcinoma in Situ bisphenol A 4.8617123778
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 2.3418572023
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 9.1117572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 9.1117572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3018850075 16120746 18670907
MESH:D002318 Cardiovascular Diseases Raloxifene 3.3515775269
MESH:D002386 Cataract Acetaminophen 2.5110977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 15.286135515
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 15.2812371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 15.2817174075 2727394 7505956 21159647
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 15.2819524636 20056578
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.9519052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.9516835633
MESH:D002779 Cholestasis Cyclosporine 12.7819486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.7817681005 16105132 17333356 16919318 15861022 17110522 11677210
MESH:D002779 Cholestasis pirinixic acid 12.7819176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0516354765 15340226 12621046 8697196 15668235
MESH:D003072 Cognition Disorders Raloxifene 4.4915800139
MESH:D003092 Colitis Selenium 3.6517936198
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9514669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4415322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.4419769572
MESH:D003456 Cryptorchidism vinclozolin 4.2114966744
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.8918551238
MESH:D003711 Demyelinating Diseases Tamoxifen 4.2319031437
MESH:D003865 Depressive Disorder, Major Raloxifene 4.0517474826
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3718249437
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.1120387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.1117107852
MESH:D003928 Diabetic Nephropathies Raloxifene 8.6617451421 17308373 15920148
MESH:D003928 Diabetic Nephropathies Tamoxifen 8.6619279558
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 11.5918551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.5910774834 12153990 12392966 18713872 19370779 19739265 15968718 10915739 16109766 11287661 12705907 10663392 16485898 17906064 17522070 19923254 16781746 12540782 16177239 14550746 11421492 2444490 11834606 11529661 19416960 15619225 16227642 12594235 19085960 19164858 18071297 11743745 12958197 11739529 17562736 19420014 16081117 11461765 14986274 14725611 16393943
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 11.5919107877
MESH:D056486 Drug-Induced Liver Injury Selenium 11.5915131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.5920420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6611462148
MESH:C538011 Eales disease Vitamin E 4.579068938
MESH:D004487 Edema pirinixic acid 10.7312083418
MESH:D004487 Edema Raloxifene 10.7315860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 10.7311000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7716714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 14.6112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 14.6115845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 14.6119031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 2.9619155303 17893378 20544844 16202921
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.919294722 10568697
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9916302075
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9111564622
MESH:D005234 Fatty Liver Cyclosporine 29.1519224547
MESH:D005234 Fatty Liver Diethylnitrosamine 29.1520387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 29.1515345470
MESH:D005234 Fatty Liver pirinixic acid 29.1519236843 20131406
MESH:D005234 Fatty Liver Raloxifene 29.1517473493
MESH:D005234 Fatty Liver Tamoxifen 29.1519224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.1616709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3311858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.4014745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.0519069698
MESH:D005355 Fibrosis Cyclosporine 8.0512168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.0520067830
MESH:D005756 Gastritis Acetaminophen 3.5516983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.8016973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.1716417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.5516452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.098708960
MESH:D006042 Goiter perchlorate 5.1818801409
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4710696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.3410048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 6.3416080930
MESH:D006331 Heart Diseases Raloxifene 3.4411110106
MESH:D006333 Heart Failure pirinixic acid 6.6820558911
MESH:D006333 Heart Failure Selenium 6.6817162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2915720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2111000095
MESH:D006529 Hepatomegaly pirinixic acid 7.8319176532 18467677 16221962 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.8312621046 16120746 15340226
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6616863852 16490937
MESH:D006689 Hodgkin Disease sodium arsenite 3.0412676792
MESH:D019584 Hot Flashes Vitamin E 3.8414716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9215340226 16959395 18606429 8697196 16354765
MESH:D006930 Hyperalgesia Acetaminophen 2.6016870215
MESH:D006943 Hyperglycemia pirinixic acid 3.0720558911
MESH:D006973 Hypertension Cyclosporine 8.2910903974
MESH:D006973 Hypertension Raloxifene 8.2917577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.2918670907 18850075
MESH:D006980 Hyperthyroidism Methimazole 5.4914678291
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6816569931 16945680
MESH:D007037 Hypothyroidism Methimazole 11.5218031379
MESH:D007037 Hypothyroidism Propylthiouracil 11.528137927 18031379
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3412013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 10.7017937319
MESH:D007248 Infertility, Male sodium arsenite 10.7012646999 15346721
MESH:D007248 Infertility, Male vinclozolin 10.7016467254
MESH:D007249 Inflammation Diethylnitrosamine 7.8718785209
MESH:D007249 Inflammation Tamoxifen 7.8719457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 7.8712200463 12878042
MESH:D007251 Influenza, Human Selenium 10.5316624496
MESH:D007251 Influenza, Human Vitamin E 10.5316624496
MESH:D007333 Insulin Resistance bisphenol A 7.0316393666
MESH:D007333 Insulin Resistance pirinixic acid 7.0316306350
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 4.4710783313
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2116580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3115604871
MESH:D007674 Kidney Diseases Acetaminophen 18.2712587719 15629191
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 18.2715369732
MESH:D007674 Kidney Diseases Cyclosporine 18.2718776723 10903974 8314463
MESH:D007674 Kidney Diseases sodium arsenite 18.2720008137
MESH:D007674 Kidney Diseases Vitamin E 18.2712488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.7616518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 11.7516705839
MESH:D007680 Kidney Neoplasms Cyclosporine 11.7512371664
MESH:D007680 Kidney Neoplasms Tamoxifen 11.7518625569
MESH:D007889 Leiomyoma Raloxifene 4.3716973256
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 3.9116766008
MESH:D007984 Leydig Cell Tumor vinclozolin 4.6016417039
MESH:D008064 Lipidoses Tamoxifen 3.0617567588 15342952
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.7518665156 18407596 19638242 20032147 18522880
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.7915474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.7918564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.7912878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 4.7916169303
MESH:D008107 Liver Diseases Acetaminophen 3.7912969438 12587719 19460945 16611625 19014921 11587558 16610002 19784758
MESH:D008107 Liver Diseases Diethylnitrosamine 3.7917034775
MESH:D017114 Liver Failure, Acute Acetaminophen 3.1216871587 17185352
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 21.157678174
MESH:D008113 Liver Neoplasms Aflatoxin B1 21.159163691 15890375 2125692 18177683
MESH:D008113 Liver Neoplasms Diethylnitrosamine 21.1519499222 20583210 19638242 19255062 21278145 19254457 19294768 18648771 19426721 20101389 19690152 21167192 18644402 2862719 12112319 19996281 12771043 15175105 20137499 18977376 20452335 20405173 9163691 19256749 19833225 10737359 20501860 21071580 2422723 20434301 20118626 18754104 20492335 19427195 19073162 19642983 15885732 19812893 19551842 19090486 21047994 16942905 18978307 19850985
MESH:D008113 Liver Neoplasms pirinixic acid 21.1520007298 16377806 15890375
MESH:D008113 Liver Neoplasms sodium arsenite 21.1516712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 21.1516684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 21.1516984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 13.442876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 13.448603461
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 13.4416267830 18093689 19539802 18544905 18775883 3124819 19009564 18079962 19519916 2563599 18282651 21159647 16842330 19004024 9362446 18164116 18253720 17854601 17942915 18308698 19126423 17174075
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.4412151625
MESH:D008171 Lung Diseases sodium arsenite 7.1519095001
MESH:D008171 Lung Diseases Vitamin E 7.1516863852
MESH:D008175 Lung Neoplasms Aflatoxin B1 8.3414755239
MESH:D008175 Lung Neoplasms Diethylnitrosamine 8.3420970405 6695378 21163286 20512841
MESH:D008175 Lung Neoplasms sodium arsenite 8.3415276417 17077188 19931552 16712894 17306315
MESH:D008175 Lung Neoplasms Tamoxifen 8.3418625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.3411884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 8.3411062179
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.6319428831
MESH:D008325 Mammary Neoplasms, Experimental Selenium 5.7715318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 5.7711731420 19196722 14580682 19196723 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 4.4219453300
MESH:D008545 Melanoma sodium arsenite 3.2416487513 19082730
MESH:D008545 Melanoma Tamoxifen 3.2419393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.0515990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4419513568
MESH:D008654 Mesothelioma Selenium 2.7415107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6616801185
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.4315863610
MESH:D009101 Multiple Myeloma Raloxifene 3.3516497877
MESH:D009135 Muscular Diseases pirinixic acid 3.3816239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.0919151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9112213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8416411023
MESH:D009232 Myxoma Raloxifene 5.4316343187
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.737678174 18551238
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.563581430 9029167
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.5619393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4719410462
MESH:D009369 Neoplasms pirinixic acid 4.7317405874
MESH:D009369 Neoplasms sodium arsenite 4.7311559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.5420056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.8719200415 19189210 19196722
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1719348381 18481113
MESH:D009421 Nervous System Malformations bisphenol A 9.1611399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.1614600291
MESH:D009436 Neural Tube Defects sodium arsenite 3.0612854658
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.8218514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.8220387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9920387270
MESH:D009765 Obesity pirinixic acid 1.7820558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.3216049721
MESH:D010024 Osteoporosis Raloxifene 3.3119059307 17882678 15775268
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.1015758505 17823083 15579764 17893378
MESH:D010049 Ovarian Diseases bisphenol A 4.8611985600
MESH:D010051 Ovarian Neoplasms sodium arsenite 2.4017306315 15276417
MESH:D010146 Pain Acetaminophen 2.2916870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.3816540662
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5611578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1212520081
MESH:D010787 Photosensitivity Disorders 4-hydroxy-2-nonenal 5.3711550810
MESH:D010954 Plasmacytoma Selenium 4.7615087411
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4318163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.5712371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.572563599
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 15.5010548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 15.5011118676 11399792 11896295 11222880
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 15.5018220299 19015723 18042343
MESH:D011469 Prostatic Diseases vinclozolin 4.8018220299
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.0920887781
MESH:D011471 Prostatic Neoplasms bisphenol A 1.8816740699
MESH:D011471 Prostatic Neoplasms Raloxifene 1.8816220300 16536755 15731164
MESH:D011471 Prostatic Neoplasms sodium arsenite 1.8816039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.8815067354
MESH:D011471 Prostatic Neoplasms Vitamin E 1.8815084515
MESH:D011472 Prostatitis vinclozolin 4.8018629315
MESH:D011537 Pruritus Ethinyl Estradiol 3.1816919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.1816882103
MESH:D011629 Puberty, Precocious bisphenol A 4.6510548101
MESH:D011693 Purpura Raloxifene 5.4315770314
MESH:D015427 Reperfusion Injury pirinixic acid 2.3219058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7118990726
MESH:D012640 Seizures 2,6-dinitrotoluene 2.4518551238
MESH:D012871 Skin Diseases Vitamin E 2.4118709164
MESH:D012878 Skin Neoplasms sodium arsenite 9.0918572023 19524636
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 9.098532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.0916192470
MESH:D013088 Spermatocele Ethinyl Estradiol 11.1316709447
MESH:D013088 Spermatocele Tamoxifen 11.1316709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.9119457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.6912854658
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7518456281
MESH:D020521 Stroke Raloxifene 8.3616837676
MESH:D020521 Stroke Vitamin E 8.3616517955
MESH:D019966 Substance-Related Disorders bisphenol A 3.8516684133 16045194
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0415669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7712697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 7.087505956
MESH:D013964 Thyroid Neoplasms Propylthiouracil 7.0815710170
MESH:D013978 Tibial Fractures Raloxifene 5.0819048282
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 11.5316049721
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 11.5317572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 11.5317306315 11723127 16452187 16712894
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 11.5316712894 8653321 17572228
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.1910091137
MESH:D014581 Urticaria Acetaminophen 2.8510982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.6511813266
MESH:D014591 Uterine Diseases bisphenol A 4.8814652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1714692618
MESH:D014605 Uveitis Cyclosporine 3.851336536
MESH:D014652 Vascular Diseases sodium arsenite 4.2917056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4712125929
MESH:D054556 Venous Thromboembolism Raloxifene 5.0816837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4214671159 15869587
MESH:D014846 Vulvar Neoplasms Raloxifene 5.4316343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1215886252
MESH:D014985 Xerophthalmia Cyclosporine 4.3117120751
Pathway ID Pathway Name
KEGG:04530 Tight junction
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved