AutismKB 2.0

Annotation Detail for MICALL1


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Basic Information Top
Gene Symbol:MICALL1 ( DKFZp686M2226,FLJ45921,KIAA1668,MICAL-L1,MIRAB13 )
Gene Full Name: MICAL-like 1
Band: 22q13.1
Quick LinksEntrez ID:85377; OMIM: NA; Uniprot ID:MILK1_HUMAN; ENSEMBL ID: ENSG00000100139; HGNC ID: 29804
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
P00034Integrin signalling pathway
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of MICALL1 mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of MICALL1 proteinaffects expression 20106945
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of MICALL1 mRNAincreases expression 20106945
D016572 Cyclosporine Cyclosporine results in increased expression of MICALL1 mRNAincreases expression 20106945
D004958 Estradiol Estradiol results in increased expression of MICALL1 mRNAincreases expression 20106945
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.5220127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 4.5211473722
MESH:D000236 Adenoma Benzo(a)pyrene 2.846695378
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.5619183758
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0217474063 20146248
MESH:D001943 Breast Neoplasms Estradiol 2.0217261762 12948864 16675129 17289903 19861407 18497071 17018787 14630087
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 5.0016111702
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.783084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 4.7821507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Estradiol 4.7816924424
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1320419170
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.3612371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 7.3618566989
MESH:D002779 Cholestasis Cyclosporine 3.1719486331
MESH:D003928 Diabetic Nephropathies Estradiol 3.7419279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6619923254 11461765 16485898 14725611 14550746 11287661 2444490 11834606 12540782 12958197 16393943 11421492 11529661 19739265 15619225 16177239 16081117 17906064 19370779 10663392 16109766 18071297 12594235 19085960 19164858 14986274 12392966 15968718 11743745 12153990 11739529 16781746 19420014 12705907 10774834 10915739 17562736 17522070 18713872 19416960 16227642
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D016889 Endometrial Neoplasms Estradiol 3.2018566989 19148513 11473722
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0716530937
MESH:D005234 Fatty Liver Cyclosporine 3.2319224547
MESH:D005355 Fibrosis Cyclosporine 3.6212639820 12168785
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.768708960
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8220471113
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.9615720958
MESH:D006558 Herpes Genitalis Estradiol 5.6415709030
MESH:D019584 Hot Flashes Estradiol 4.3617088409
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D006973 Hypertension Cyclosporine 2.2010903974
MESH:D007333 Insulin Resistance Estradiol 3.1816627594 16393666
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.0515604871
MESH:D007674 Kidney Diseases Acetaminophen 11.0612587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 11.0618776723 10903974 8314463
MESH:D007674 Kidney Diseases Estradiol 11.0615618244
MESH:D007680 Kidney Neoplasms Cyclosporine 8.3012371664
MESH:D007680 Kidney Neoplasms Estradiol 8.3015610895
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 1.6814716833 14659978
MESH:D008107 Liver Diseases Acetaminophen 1.6911587558 19784758 16611625 19014921 12587719 19460945 16610002 12969438
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5817185352 16871587
MESH:D008113 Liver Neoplasms Aflatoxin B1 4.939163691 15890375 2125692 18177683
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.9321137059 20195826
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 2.948603461
MESH:D008175 Lung Neoplasms Aflatoxin B1 2.5014755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.5018816296 17053015 20064080 18520028 20869020 20135361 18569708 6695378 20464547
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.7711807958 17203775 11408345 16891317
MESH:D020149 Manganese Poisoning Estradiol 5.0919453300
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.4016801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4616381670
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.5516810080
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3111141357
MESH:D009389 Neovascularization, Pathologic Estradiol 4.2717289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.0517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6118481113 19348381
MESH:D009421 Nervous System Malformations Estradiol 4.0916427766 11399458
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D010051 Ovarian Neoplasms Estradiol 2.3019401270
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D011230 Precancerous Conditions Cyclosporine 3.5512371664
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.2620887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.0317292933
MESH:D011471 Prostatic Neoplasms Estradiol 3.0316740699
MESH:D011565 Psoriasis Cyclosporine 2.3216882103
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5119755658 10029692
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.5620155912 2093021
MESH:D013978 Tibial Fractures Estradiol 5.3019048282
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.2917053015
MESH:D014581 Urticaria Acetaminophen 3.3810982225
MESH:D014605 Uveitis Cyclosporine 4.591336536
MESH:D014985 Xerophthalmia Cyclosporine 5.0517120751
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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