AutismKB 2.0

Annotation Detail for EAF1


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Basic Information Top
Gene Symbol:EAF1 ( - )
Gene Full Name: ELL associated factor 1
Band: 3p25.1
Quick LinksEntrez ID:85403; OMIM: 608315; Uniprot ID:EAF1_HUMAN; ENSEMBL ID: ENSG00000144597; HGNC ID: 20907
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of EAF1 mRNAaffects expression 17562736
D016589 Astemizole Astemizole results in increased expression of EAF1 mRNAincreases expression 20221588
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 16.0410982225
MESH:D000799 Angioedema Astemizole 16.042883202
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8310977129
MESH:D004244 Dizziness Astemizole 7.543105558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6819420014 11739529 12594235 16393943 19164858 11529661 12958197 16485898 16177239 16781746 14986274 12392966 11834606 12540782 19085960 11743745 16227642 17562736 16109766 14725611 18071297 12705907 19416960 10774834 10915739 12153990 19739265 18713872 11287661 10663392 15968718 19923254 16081117 14550746 17906064 2444490 17522070 15619225 11421492 19370779 11461765
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.1719426721
MESH:D004802 Eosinophilia Astemizole 5.561355641
MESH:D005499 Folliculitis Astemizole 6.991671328
MESH:D005756 Gastritis Acetaminophen 4.7416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1116870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4412587719 15629191
MESH:D017513 Lichen Nitidus Astemizole 7.542563723
MESH:D008107 Liver Diseases Acetaminophen 1.7119460945 19014921 12587719 19784758 16610002 12969438 11587558 16611625
MESH:D017114 Liver Failure, Acute Acetaminophen 3.7416871587 17185352
MESH:D008133 Long QT Syndrome Astemizole 4.9818472280 11989578
MESH:D008288 Malaria Astemizole 5.0516816845
MESH:D008546 Melanoma, Experimental Acetaminophen 4.3319513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3118514411
MESH:D009759 Nystagmus, Pathologic Astemizole 7.546135121
MESH:D010146 Pain Acetaminophen 2.8216870215
MESH:D012221 Rhinitis, Allergic, Perennial Astemizole 6.5010822083
MESH:D016171 Torsades de Pointes Astemizole 6.099583453 8256756
MESH:D014581 Urticaria Acetaminophen 11.1210982225
MESH:D014581 Urticaria Astemizole 11.122147912 3080510 3134034 3097109 1683191 1976298 2568189 2565098 2885854 2568013 2859714 2883202
MESH:D014717 Vertigo Astemizole 7.543105558
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018