AutismKB 2.0

Annotation Detail for RUNX2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RUNX2 ( AML3,CBFA1,CCD,CCD1,MGC120022,MGC120023,OSF-2,OSF2,PEA2aA,PEBP2A1,PEBP2A2,PEBP2aA,PEBP2aA1 )
Gene Full Name: runt-related transcription factor 2
Band: 6p21.1
Quick LinksEntrez ID:860; OMIM: 600211; Uniprot ID:RUNX2_HUMAN; ENSEMBL ID: ENSG00000124813; HGNC ID: 10472
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
No data
Pathway IDPathway Name
200189FGF signaling pathway
200002Regulation of nuclear SMAD2/3 signaling
200191Regulation of retinoblastoma protein
200196Notch-mediated HES/HEY network
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1824Bone disease
1902Kidney failure
1934Cancer
2138Osteoporosis
2259Hereditary disease
Desease Name
height
bone size
Bone Mineral Density
bone density
METABOLIC
DEVELOPMENTAL
Diabetes Mellitus, Type 2
No data
Desease Name
Cleidocranial dysplasia
Dental anomalies, isolated
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RUNX2 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in decreased expression of RUNX2 mRNAdecreases expression 20458559
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of RUNX2 mRNAincreases expression 18687144
D001554 Benzene Benzene results in decreased expression of RUNX2 mRNAdecreases expression 15120971
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of RUNX2 mRNAaffects expression 20382639
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RUNX2 mRNAdecreases expression 19150397
C070515 bisindolylmaleimide I bisindolylmaleimide I inhibits the reaction [FGF2 protein results in increased expression of RUNX2 mRNA]decreases reaction|increases expression 12403780
C058819 calphostin C calphostin C inhibits the reaction [FGF2 protein results in increased expression of and results in increased activity of RUNX2 protein]decreases reaction|increases activity|increases expression 12403780
C058819 calphostin C calphostin C inhibits the reaction [FGF2 protein results in increased expression of RUNX2 mRNA]decreases reaction|increases expression 12403780
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of RUNX2 mRNAaffects expression 17484886
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of RUNX2 mRNAincreases expression 17334410
D002251 Carbon Tetrachloride FR 167653 inhibits the reaction [Carbon Tetrachloride results in increased expression of RUNX2 mRNA]decreases reaction|increases expression 17334410
C018021 cobaltous chloride cobaltous chloride results in decreased expression of RUNX2 mRNAdecreases expression 16772336
C010564 cryptoxanthin [cryptoxanthin co-treated with Vitamin A] results in increased expression of RUNX2 mRNAaffects cotreatment|increases expression 15962303
C010564 cryptoxanthin cryptoxanthin results in increased expression of RUNX2 mRNAincreases expression 15962303
C010564 cryptoxanthin Cycloheximide inhibits the reaction [cryptoxanthin results in increased expression of RUNX2 mRNA]decreases reaction|increases expression 15962303
C010564 cryptoxanthin Dichlororibofuranosylbenzimidazole inhibits the reaction [cryptoxanthin results in increased expression of RUNX2 mRNA]decreases reaction|increases expression 15962303
D003474 Curcumin Curcumin results in decreased expression of RUNX2 proteindecreases expression 15129424
D003513 Cycloheximide Cycloheximide inhibits the reaction [cryptoxanthin results in increased expression of RUNX2 mRNA]decreases reaction|increases expression 15962303
D003676 Deferoxamine Deferoxamine results in decreased expression of RUNX2 mRNAdecreases expression 16772336
D004004 Dichlororibofuranosylbenzimidazole Dichlororibofuranosylbenzimidazole inhibits the reaction [cryptoxanthin results in increased expression of RUNX2 mRNA]decreases reaction|increases expression 15962303
D002117 Calcitriol Calcitriol promotes the reaction [VDR protein binds to RUNX2 enhancer]affects binding|increases reaction 17293108
D002117 Calcitriol Calcitriol results in decreased expression of RUNX2 mRNAdecreases expression 16002434
D002117 Calcitriol Calcitriol results in decreased expression of RUNX2 mRNAdecreases expression 17293108
D004365 Drugs, Chinese Herbal Drugs, Chinese Herbal results in increased expression of RUNX2 mRNAincreases expression 16543677
D004958 Estradiol Estradiol results in increased expression of RUNX2 mRNAincreases expression 16202921
17689939
D004958 Estradiol fulvestrant inhibits the reaction [Estradiol results in increased expression of RUNX2 mRNA]decreases reaction|increases expression 17689939
D004958 Estradiol Estradiol affects the expression of RUNX2 mRNAaffects expression 17166402
D005419 Flavonoids Flavonoids results in increased expression of RUNX2 mRNAincreases expression 16543677
C104334 FR 167653 FR 167653 inhibits the reaction [Carbon Tetrachloride results in increased expression of RUNX2 mRNA]decreases reaction|increases expression 17334410
C070081 fulvestrant fulvestrant inhibits the reaction [Estradiol results in increased expression of RUNX2 mRNA]decreases reaction|increases expression 17689939
C070081 fulvestrant fulvestrant inhibits the reaction [resveratrol results in increased expression of RUNX2 mRNA]decreases reaction|increases expression 17689939
D019833 Genistein Genistein affects the expression of RUNX2 mRNAaffects expression 17166402
D006851 Hydrochloric Acid Hydrochloric Acid results in increased expression of RUNX2 mRNAincreases expression 17183249
D006851 Hydrochloric Acid Hydrochloric Acid results in increased expression of RUNX2 proteinincreases expression 17183249
C056599 icariin icariin results in increased expression of RUNX2 mRNAincreases expression 19747809
18295595
C056599 icariin NOG protein inhibits the reaction [icariin results in increased expression of RUNX2 mRNA]decreases reaction|increases expression 18295595
19747809
C056599 icariin icariin results in increased expression of RUNX2 mRNAincreases expression 20019778
C093875 montelukast montelukast results in increased expression of RUNX2 mRNAincreases expression 19544365
C093973 PD 98059 PD 98059 inhibits the reaction [resveratrol results in increased expression of RUNX2 mRNA]decreases reaction|increases expression 17689939
C093973 PD 98059 PD 98059 results in decreased expression of RUNX2 mRNAdecreases expression 17689939
D011794 Quercetin Quercetin results in increased expression of RUNX2 mRNAincreases expression 16996034
D011794 Quercetin Quercetin results in increased expression of RUNX2 mRNAincreases expression 17243115
D020849 Raloxifene Raloxifene affects the expression of RUNX2 mRNAaffects expression 17166402
C059514 resveratrol fulvestrant inhibits the reaction [resveratrol results in increased expression of RUNX2 mRNA]decreases reaction|increases expression 17689939
C059514 resveratrol PD 98059 inhibits the reaction [resveratrol results in increased expression of RUNX2 mRNA]decreases reaction|increases expression 17689939
C059514 resveratrol resveratrol results in increased expression of RUNX2 mRNAincreases expression 17689939
C059514 resveratrol resveratrol results in increased expression of RUNX2 mRNAincreases expression 16813520
C085746 rottlerin rottlerin inhibits the reaction [FGF2 protein results in increased activity of RUNX2 protein]decreases reaction|increases activity 12403780
C085746 rottlerin rottlerin inhibits the reaction [FGF2 protein results in increased expression of RUNX2 mRNA]decreases reaction|increases expression 12403780
D013749 Tetrachlorodibenzodioxin AHR protein affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of RUNX2 mRNA]affects reaction|decreases expression 19264158
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of RUNX2 mRNAdecreases expression 19264158
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of RUNX2 mRNAincreases expression 17586704
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of RUNX2 mRNAdecreases expression 19264158
19201780
D014028 Tobacco Smoke Pollution Tobacco Smoke Pollution results in increased expression of RUNX2 mRNAincreases expression 18087596
D014212 Tretinoin Tretinoin results in increased expression of RUNX2 mRNAincreases expression 16350840
C057693 troglitazone troglitazone results in decreased expression of RUNX2 mRNAdecreases expression 16813520
D014801 Vitamin A [cryptoxanthin co-treated with Vitamin A] results in increased expression of RUNX2 mRNAaffects cotreatment|increases expression 15962303
D009536 Niacinamide Niacinamide results in decreased expression of RUNX2 mRNAdecreases expression 16813520
D009536 Niacinamide Niacinamide results in increased expression of RUNX2 mRNAincreases expression 16813520
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.5014514962 11752688 15322242
MESH:D000015 Abnormalities, Multiple Vitamin A 4.5510992263
MESH:D000038 Abscess Drugs, Chinese Herbal 5.9515043669
MESH:D000138 Acidosis Ammonium Chloride 9.5518287403
MESH:D000138 Acidosis Hydrochloric Acid 9.5512771618 20872349 16144966 15920416 11574821 19262391
MESH:D000141 Acidosis, Renal Tubular Hydrochloric Acid 5.4217183249
MESH:D000142 Acidosis, Respiratory Hydrochloric Acid 5.4520597076
MESH:D058186 Acute Kidney Injury resveratrol 3.5416538975
MESH:D055371 Acute Lung Injury Hydrochloric Acid 4.4616759491 15970105 11850527 19060228 19760209 19094174 11953099
MESH:D000230 Adenocarcinoma arsenic trioxide 6.5519825857 11798837
MESH:D000230 Adenocarcinoma Estradiol 6.5511473722
MESH:D000230 Adenocarcinoma Genistein 6.5511473722
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Tobacco Smoke Pollution 5.1715814487
MESH:D000236 Adenoma resveratrol 3.1115688382
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.0216835633
MESH:D000419 Albuminuria Raloxifene 4.2617451421 17308373
MESH:D019973 Alcohol-Related Disorders Curcumin 4.7217887948
MESH:D000505 Alopecia Tretinoin 3.3415955085
MESH:D000544 Alzheimer Disease Curcumin 8.8015590663
MESH:D000544 Alzheimer Disease icariin 8.8019782061 19858766
MESH:D000544 Alzheimer Disease Raloxifene 8.8015800139
MESH:D000544 Alzheimer Disease resveratrol 8.8016183991 16162502
MESH:D000740 Anemia Drugs, Chinese Herbal 13.2717963324 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 13.2711748828
MESH:D000740 Anemia Vitamin A 13.2716960172
MESH:D000741 Anemia, Aplastic Benzene 4.1011369114 17661222 14761424
MESH:D000743 Anemia, Hemolytic Quercetin 3.9217084956
MESH:D018798 Anemia, Iron-Deficiency Vitamin A 4.4916960172
MESH:D000787 Angina Pectoris Drugs, Chinese Herbal 5.0611477813
MESH:D000799 Angioedema montelukast 5.7010982225
MESH:D000860 Anoxia Hydrochloric Acid 4.9515090967
MESH:D001004 Anus Diseases Drugs, Chinese Herbal 5.6015043669
MESH:D001169 Arthritis, Experimental resveratrol 6.7817115116
MESH:D001169 Arthritis, Experimental Tretinoin 6.7816412693
MESH:D015210 Arthritis, Gouty Drugs, Chinese Herbal 5.4019655406
MESH:D001172 Arthritis, Rheumatoid Curcumin 7.0016807698
MESH:D001172 Arthritis, Rheumatoid Tobacco Smoke Pollution 7.0019898480
MESH:D001172 Arthritis, Rheumatoid Tretinoin 7.0016292516
MESH:D001249 Asthma montelukast 7.5417895592 10852428 19681236 19667530 16293801 20332717
MESH:D001249 Asthma Tretinoin 7.5416456186
MESH:D001249 Asthma Vitamin A 7.5416732791
MESH:D055963 Asthma, Aspirin-Induced montelukast 5.1619667532
MESH:D001250 Asthma, Exercise-Induced montelukast 5.5310984370 19667531
MESH:D001260 Ataxia Telangiectasia Quercetin 4.6215336622
MESH:D050197 Atherosclerosis Curcumin 6.2118704882
MESH:D050197 Atherosclerosis resveratrol 6.2117967414 16873680
MESH:D001284 Atrophy fulvestrant 4.5111514358
MESH:D001327 Autoimmune Diseases Curcumin 9.7119761891
MESH:D001327 Autoimmune Diseases Quercetin 9.7119761891
MESH:D001471 Barrett Esophagus Tretinoin 4.0616935849
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 19.4316206674
MESH:D001778 Blood Coagulation Disorders Hydrochloric Acid 19.4315920416
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 19.4312125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 19.4316206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4315340226
MESH:D001847 Bone Diseases icariin 6.0518295595
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5415746008
MESH:D001855 Bone Marrow Diseases Benzene 4.8716183116
MESH:D001862 Bone Resorption Drugs, Chinese Herbal 4.519881647
MESH:D001930 Brain Injuries Raloxifene 4.1316580743
MESH:D002545 Brain Ischemia Curcumin 15.1916770732
MESH:D002545 Brain Ischemia icariin 15.1919303870
MESH:D002545 Brain Ischemia resveratrol 15.1917600658
MESH:D001932 Brain Neoplasms Curcumin 3.6317596214
MESH:D001943 Breast Neoplasms Benzene 9.1611921183 17162533
MESH:D001943 Breast Neoplasms Calcitriol 9.1611237771
MESH:D001943 Breast Neoplasms Curcumin 9.1619250217 16243823 18462866 18593918
MESH:D001943 Breast Neoplasms Deferoxamine 9.1615993339
MESH:D001943 Breast Neoplasms Estradiol 9.1619861407 16675129 17261762 12948864 17289903 14630087 18497071 17018787
MESH:D001943 Breast Neoplasms fulvestrant 9.1618984771
MESH:D001943 Breast Neoplasms Genistein 9.1617200150 16873071 16541309
MESH:D001943 Breast Neoplasms Quercetin 9.1618628248
MESH:D001943 Breast Neoplasms Raloxifene 9.1617595753 17893378 17952589 16912660 17261762 17242785 17049068 15758505 15775269 15572757 16837676 17440819
MESH:D001943 Breast Neoplasms resveratrol 9.1617651959 16393696 17534123
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 9.1620435547
MESH:D001943 Breast Neoplasms Tretinoin 9.1616166294 16443354 16873071
MESH:D016535 Bronchial Hyperreactivity Hydrochloric Acid 4.3112378975
MESH:D001986 Bronchial Spasm Hydrochloric Acid 5.1115578804
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 11.8416813970
MESH:D001997 Bronchopulmonary Dysplasia Vitamin A 11.8417426644 17377406
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.0011589617
MESH:D002105 Cadmium Poisoning Quercetin 5.1816962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.1116111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.4316050911 16227642 16011737 15700767 18705752 10355542 3786805 15721981 16097048 15673190 16192424 16124888
MESH:D002277 Carcinoma Curcumin 7.3618593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.3616835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.8016168501
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 13.0815073043 15553829 11135700 14691202 16217749
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 13.0818788625
MESH:D006528 Carcinoma, Hepatocellular Estradiol 13.0816924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 13.0816924424
MESH:D006528 Carcinoma, Hepatocellular Quercetin 13.0812508355 19519916
MESH:D006528 Carcinoma, Hepatocellular resveratrol 13.0816227395 19321006
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 13.081917145
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.2416675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 5.4918414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung Tobacco Smoke Pollution 5.4911212258
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.6117234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.5119014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.8112490120
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 13.1611237771
MESH:D002294 Carcinoma, Squamous Cell Curcumin 13.1618462866
MESH:D002294 Carcinoma, Squamous Cell resveratrol 13.1616227395
MESH:D002294 Carcinoma, Squamous Cell Tobacco Smoke Pollution 13.1611212258
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 13.1616096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 3.7717572228
MESH:D006332 Cardiomegaly Quercetin 6.1419794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.1418670907 16120746 18850075
MESH:D002318 Cardiovascular Diseases Genistein 10.8416332659
MESH:D002318 Cardiovascular Diseases Raloxifene 10.8415775269
MESH:D002318 Cardiovascular Diseases resveratrol 10.8415458977
MESH:D002386 Cataract Tretinoin 2.8817460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 5.8420889678
MESH:D002471 Cell Transformation, Neoplastic Estradiol 5.8418566989
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.2416129372
MESH:D015362 Child Nutrition Disorders Vitamin A 5.1216153327
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.8716835633
MESH:D002779 Cholestasis Vitamin A 4.0416175620
MESH:D002822 Choriocarcinoma Tretinoin 4.8016461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 9.0112621046 15340226 15668235 8697196 16354765
MESH:D002972 Cleft Palate Tretinoin 9.019407595
MESH:D002972 Cleft Palate Vitamin A 9.0116054864
MESH:D002973 Cleidocranial Dysplasia marker/mechanism 20357738 14688224
MESH:D003072 Cognition Disorders Raloxifene 4.2715800139
MESH:D003092 Colitis Curcumin 14.0916782535 16804969 18200517
MESH:D003092 Colitis resveratrol 14.0916474422
MESH:D003092 Colitis Tretinoin 14.0917035595
MESH:D003103 Coloboma Curcumin 4.2318809619
MESH:D003110 Colonic Neoplasms Curcumin 10.3119359593 16340194
MESH:D003110 Colonic Neoplasms Genistein 10.3117182828
MESH:D003110 Colonic Neoplasms Quercetin 10.3119056647 11134977 16640504 19440933 17191121 15741050 17148506
MESH:D003110 Colonic Neoplasms resveratrol 10.3116338953
MESH:D003110 Colonic Neoplasms Vitamin A 10.3117219422 16267017
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.3120501625
MESH:D015179 Colorectal Neoplasms Quercetin 3.3118095365 18852136
MESH:D015179 Colorectal Neoplasms resveratrol 3.3116550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7617141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 4.5518497527
MESH:D003327 Coronary Disease resveratrol 3.5216507316
MESH:D023903 Coronary Restenosis arsenic trioxide 3.8512609071
MESH:D019465 Craniofacial Abnormalities marker/mechanism 14688224
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 6.8610525206
MESH:D019465 Craniofacial Abnormalities Benzene 6.8615643154
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 6.8620055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 6.869125849 9211117 9224671 10589399 14991402 16925845 9664655 17551590 8800419 9142499
MESH:D019465 Craniofacial Abnormalities Vitamin A 6.8610992263
MESH:D003556 Cystitis Hydrochloric Acid 5.1112853844 12599022 19279288 20719367
MESH:D018856 Cystitis, Interstitial Hydrochloric Acid 5.4517714534
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.7715213294
MESH:D003865 Depressive Disorder, Major Raloxifene 3.8717474826
MESH:D003872 Dermatitis Benzene 4.4215902427
MESH:D017449 Dermatitis, Allergic Contact cobaltous chloride 3.7016823706 11298694 15059100
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 7.6119496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 7.6116873680
MESH:D003922 Diabetes Mellitus, Type 1 Vitamin A 3.4016506275
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 12.6518403477
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 12.6516647724
MESH:D003924 Diabetes Mellitus, Type 2 Niacinamide 12.6519647726
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 12.6517107852
MESH:D003924 Diabetes Mellitus, Type 2 troglitazone 12.6516023994
MESH:D003925 Diabetic Angiopathies troglitazone 5.2812601628
MESH:D003928 Diabetic Nephropathies Curcumin 19.0318204486
MESH:D003928 Diabetic Nephropathies Estradiol 19.0319279558
MESH:D003928 Diabetic Nephropathies Raloxifene 19.0315920148 17451421 17308373
MESH:D003928 Diabetic Nephropathies resveratrol 19.0316286809
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 8.157179309 19336974 10092053 16227642 7120509 16177239 10915739 19085960 21278145 15968718 6884620 7440962 15998439 4309450 3786805 9327722 15027814 2869522 6623471 17522070 11566570 3732212
MESH:D056486 Drug-Induced Liver Injury Drugs, Chinese Herbal 8.1515027814
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 8.1520420201
MESH:D056486 Drug-Induced Liver Injury troglitazone 8.1514986274
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.5011462148
MESH:D015352 Dry Eye Syndromes Vitamin A 5.4516146918
MESH:D004381 Duodenal Ulcer Curcumin 3.7217351913
MESH:C538011 Eales disease Vitamin A 5.269068938
MESH:D004480 Ectromelia Vitamin A 5.4616054864
MESH:D004487 Edema bisindolylmaleimide I 13.978273558
MESH:D004487 Edema Raloxifene 13.9715860553
MESH:D004487 Edema resveratrol 13.978985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 13.9712711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.7415322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 10.7418230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 13.5715138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 13.5715845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 13.5717872969
MESH:D004714 Endometrial Hyperplasia Genistein 4.2316402032
MESH:D016889 Endometrial Neoplasms Estradiol 11.1219148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Genistein 11.1211473722
MESH:D016889 Endometrial Neoplasms Tretinoin 11.1216569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.7210568697 9294722
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.5017923197
MESH:D004802 Eosinophilia montelukast 4.8610335014
MESH:D007172 Erectile Dysfunction icariin 5.0915329286 16281085
MESH:D004935 Esophageal Diseases Hydrochloric Acid 5.4419566590
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.1320426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.1312903497
MESH:D004941 Esophagitis Hydrochloric Acid 5.6412928072
MESH:D004942 Esophagitis, Peptic Hydrochloric Acid 5.6520516732 14621274 11346197
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.9611564622
MESH:D005124 Eye Abnormalities Tretinoin 7.969664655 16938888
MESH:D005234 Fatty Liver arsenic trioxide 16.2515073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 16.2517595544 61145 16239168 19224547 15959796 12795759 16045604 12631006
MESH:D005234 Fatty Liver Curcumin 16.2519297423
MESH:D005234 Fatty Liver Raloxifene 16.2517473493
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1111858732
MESH:D005327 Fetal Resorption Vitamin A 5.0016054864
MESH:D005355 Fibrosis Carbon Tetrachloride 30.0218705752
MESH:D005355 Fibrosis Curcumin 30.0218705752
MESH:D005355 Fibrosis Hydrochloric Acid 30.0218497604
MESH:D005355 Fibrosis Quercetin 30.0219474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 30.0220067830
MESH:D005355 Fibrosis Tretinoin 30.0217994277
MESH:D005596 Fractures, Closed montelukast 5.7819544365
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.9316904648
MESH:D005739 Gas Poisoning Hydrochloric Acid 5.1112378975
MESH:D005764 Gastroesophageal Reflux Hydrochloric Acid 4.9920545468 12212954 19957777 19951613 20616304 20516732
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.3518462866
MESH:D005909 Glioblastoma Curcumin 15.0717596214
MESH:D005909 Glioblastoma Genistein 15.0716598420
MESH:D005909 Glioblastoma Quercetin 15.0719804834
MESH:D005909 Glioblastoma Tretinoin 15.0717312396
MESH:D005910 Glioma Quercetin 2.9117643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2310696789
MESH:D006258 Head and Neck Neoplasms Curcumin 7.1018462866 18829502
MESH:D006258 Head and Neck Neoplasms Tretinoin 7.1016096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.8016084493
MESH:D006356 Heartburn Hydrochloric Acid 5.4419566590
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.1510048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 10.1514991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin A 10.1510992263 16080930
MESH:D006331 Heart Diseases Raloxifene 3.2911110106
MESH:D006402 Hematologic Diseases Benzene 4.3316183116
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0211000095
MESH:D006505 Hepatitis Carbon Tetrachloride 8.5819900420 19110552
MESH:D006505 Hepatitis Drugs, Chinese Herbal 8.5818339527
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.5515340226 16120746 12621046
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.6917701891
MESH:D006548 Hernia, Diaphragmatic Vitamin A 3.4916877224 16292552 15707848 17436238 16863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 4.6715709030
MESH:D006561 Herpes Simplex resveratrol 3.8316876885
MESH:D015658 HIV Infections Vitamin A 3.6316960176
MESH:D006679 HIV Seropositivity Vitamin A 5.2417209195
MESH:D019584 Hot Flashes Estradiol 3.3917088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.6815340226 16959395 8697196 16354765 18606429
MESH:D006930 Hyperalgesia Tretinoin 2.9416870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.1816899240
MESH:D006937 Hypercholesterolemia Curcumin 8.3418704882
MESH:D006937 Hypercholesterolemia resveratrol 8.3417188708
MESH:D006940 Hyperemia Hydrochloric Acid 5.3012646421
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.2216778211
MESH:D006943 Hyperglycemia Quercetin 3.7318262572 11834736
MESH:D006949 Hyperlipidemias resveratrol 3.7016873680
MESH:D006973 Hypertension Benzene 11.2517940673
MESH:D006973 Hypertension Quercetin 11.2518356687
MESH:D006973 Hypertension Raloxifene 11.2517577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 11.2518850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 10.2615338365
MESH:D006975 Hypertension, Portal Hydrochloric Acid 10.2616984587
MESH:D006976 Hypertension, Pulmonary Hydrochloric Acid 4.2019262391
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.0017488730
MESH:D006986 Hypervitaminosis A Vitamin A 5.8116054864
MESH:D007022 Hypotension Hydrochloric Acid 4.4311574821
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.3017600658
MESH:D007248 Infertility, Male fulvestrant 3.5211514358
MESH:D007249 Inflammation bisindolylmaleimide I 25.348273558
MESH:D007249 Inflammation Curcumin 25.3416956363 18403477 17151092
MESH:D007249 Inflammation Flavonoids 25.3417296493
MESH:D007249 Inflammation Hydrochloric Acid 25.3411574821
MESH:D007249 Inflammation montelukast 25.3418059327
MESH:D007249 Inflammation resveratrol 25.3416366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 25.3412200463 12878042
MESH:D007249 Inflammation Tobacco Smoke Pollution 25.3418590791
MESH:D015212 Inflammatory Bowel Diseases Curcumin 3.0618596194 18200517
MESH:D007251 Influenza, Human Quercetin 9.9916624496
MESH:D007251 Influenza, Human resveratrol 9.9916624496
MESH:D007333 Insulin Resistance Estradiol 2.7416627594 16393666
MESH:D007410 Intestinal Diseases Hydrochloric Acid 8.9711574821
MESH:D007410 Intestinal Diseases Tretinoin 8.9717994277
MESH:D007414 Intestinal Neoplasms Curcumin 3.9110783313
MESH:D019586 Intracranial Hypertension Vitamin A 5.4615955940
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.8816580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.8815992940 17551590
MESH:D007627 Keloid Quercetin 4.6117086741
MESH:D007674 Kidney Diseases Estradiol 5.5315618244
MESH:D007674 Kidney Diseases Quercetin 5.5316962696
MESH:D007680 Kidney Neoplasms Estradiol 2.7015610895
MESH:D007818 Laryngeal Diseases Hydrochloric Acid 6.0016498863
MESH:D007826 Laryngismus Hydrochloric Acid 6.0011510729
MESH:D007859 Learning Disorders icariin 4.9819782061
MESH:D007889 Leiomyoma Curcumin 10.0718555241
MESH:D007889 Leiomyoma Raloxifene 10.0716973256
MESH:D007938 Leukemia arsenic trioxide 22.2815070760
MESH:D007938 Leukemia Benzene 22.2818335105 17119257 14694614 15935818
MESH:D007938 Leukemia Curcumin 22.2818462866
MESH:D007938 Leukemia Genistein 22.2817468513 18980019
MESH:D007938 Leukemia Quercetin 22.2817468513
MESH:D007938 Leukemia Tretinoin 22.2817143497
MESH:D004915 Leukemia, Erythroblastic, Acute troglitazone 5.7816085563
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Drugs, Chinese Herbal 3.7715802533
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 8.7112560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 8.7116106398
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 10.5416972261
MESH:D007948 Leukemia, Monocytic, Acute PD 98059 10.5416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.1714633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 14.2119077051
MESH:D007951 Leukemia, Myeloid Benzene 14.2117506065
MESH:D007951 Leukemia, Myeloid Tretinoin 14.2116482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 8.2320471514 19850784 17050201 16467208 16968895
MESH:D015470 Leukemia, Myeloid, Acute Benzene 8.2319478238
MESH:D015470 Leukemia, Myeloid, Acute Deferoxamine 8.2320368581
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 8.2316294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 11.4312018890 17712046 17217047 17869043 16331271 19075265 15622746 12679006 15748426 15213294 16966277 12712474 19642359 16823087 19035177 11161223 17107899 16891316 11468182 17649720 16330433 9834237 15336539 16112521 19225113
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 11.4316087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 11.4317294898 17506722 19225113 9834237 16823087 17217047 17361223 12679006 17339181 15748426 19075265 16140955 17649720 16935935 17107899 17368321 16891316 17712046 19642359 16331271 16788101 17301526 19029980 16766008 19035177
MESH:D015458 Leukemia, T-Cell arsenic trioxide 10.5916882451
MESH:D015458 Leukemia, T-Cell Curcumin 10.5916106398
MESH:D017880 Limb Deformities, Congenital Tretinoin 7.669224671
MESH:D017880 Limb Deformities, Congenital Vitamin A 7.6616054864
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 18.7311408273 17157831 17174718 21278145 17334410 16943688 16221502 16239168 11903743
MESH:D008103 Liver Cirrhosis Drugs, Chinese Herbal 18.7317163593
MESH:D008103 Liver Cirrhosis FR 167653 18.7317334410
MESH:D008103 Liver Cirrhosis Hydrochloric Acid 18.7316984587
MESH:D008103 Liver Cirrhosis Vitamin A 18.7316256175
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 14.7015876570 18006644 12667390 18472332 17525996 12609069 12586293 15925388 15123356 17976157 12741479 16097048 13678700 17805973 18418968 18263696 18395914 15959796 15996030 18054572 16116963 17922224 16027843 12632514 18166357 15931870 12958196 18472094 17565644 18251166 18705752 18395095 18205269 15730626 17640975 15650968 18481824 16638106 18429990 16136751 17721639 18277467 18279442 17481882 17557913 12445418 14724832 17708605 18317297 18376398 18187930 11481614 17944888 20821823 18156304 17714472 15057751 16248980 16192424 16011737 12898905 15338365 12632512 16033810 17766677 17761835 15818738 17900296 15893842 14716496 10355542 15673190 17631135 12666154 12546737 17823541 18412020 14512876 12445421 15370692 15362042 17869086 18339082 18420326 16015684 17698563 15052691 14748882 12389079 18210741 14620537 14716833 12649538
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 14.7017355460 18705752 18006644
MESH:D008106 Liver Cirrhosis, Experimental Drugs, Chinese Herbal 14.7018237412 15383259 15818738 15763062 17629604 16610055 12632512 15849816 15339415 17036385 17348192 15641146 18371158 15744066 17881167 15864749 15754396 18567088 17666798 18606216
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 14.7014716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 14.7017823541
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 14.7012741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 14.7012878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 14.7016248980 18397230
MESH:D008106 Liver Cirrhosis, Experimental Vitamin A 14.7016248980
MESH:D008107 Liver Diseases Carbon Tetrachloride 8.6816246199 15830285 17285989 16964402 15720792
MESH:D008107 Liver Diseases Curcumin 8.6816956363
MESH:D008107 Liver Diseases Drugs, Chinese Herbal 8.6817207593
MESH:D008107 Liver Diseases Vitamin A 8.6816175620
MESH:D008108 Liver Diseases, Alcoholic Vitamin A 4.8116762690
MESH:D017093 Liver Failure Carbon Tetrachloride 3.8215123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.3814706259 16899240
MESH:D008113 Liver Neoplasms arsenic trioxide 16.1414682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 16.1419294768
MESH:D008113 Liver Neoplasms Drugs, Chinese Herbal 16.1418339527
MESH:D008113 Liver Neoplasms Quercetin 16.1418980244
MESH:D008113 Liver Neoplasms resveratrol 16.1419073162 19321006 19812893 20405173
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 16.1416984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 20.4920377131
MESH:D008114 Liver Neoplasms, Experimental Benzene 20.4912562636
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 20.4915583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Quercetin 20.4919519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 20.4912151625
MESH:D008114 Liver Neoplasms, Experimental Vitamin A 20.4917113696
MESH:D008133 Long QT Syndrome arsenic trioxide 3.0815213294
MESH:D008171 Lung Diseases Hydrochloric Acid 7.4016784557
MESH:D008171 Lung Diseases Vitamin A 7.4016863852
MESH:D017563 Lung Diseases, Interstitial Benzene 4.4514698565
MESH:D055370 Lung Injury Asbestos, Crocidolite 8.4317365036
MESH:D055370 Lung Injury Hydrochloric Acid 8.4311395602 18339021 21311175 20597076 15607125 21114838 18497604 15090967 19262391 17627322 15044056 19644408 18573544 16129981
MESH:D008175 Lung Neoplasms arsenic trioxide 9.9311798837 19825857
MESH:D008175 Lung Neoplasms Benzene 9.9312562636
MESH:D008175 Lung Neoplasms Curcumin 9.9318462866 19359593 16243823
MESH:D008175 Lung Neoplasms Drugs, Chinese Herbal 9.9318339527
MESH:D008175 Lung Neoplasms Quercetin 9.9316280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 9.9319555203 11884234
MESH:D008175 Lung Neoplasms Tobacco Smoke Pollution 9.9312111688 3440675 11091918 16288123
MESH:D008223 Lymphoma Benzene 7.0517119257 17584886
MESH:D008223 Lymphoma Curcumin 7.0518462866
MESH:D016393 Lymphoma, B-Cell resveratrol 3.9717088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.5814749477
MESH:D016399 Lymphoma, T-Cell Curcumin 4.3516173963
MESH:D015674 Mammary Neoplasms, Animal Benzene 9.0812562636
MESH:D015674 Mammary Neoplasms, Animal resveratrol 9.0815688416
MESH:D008325 Mammary Neoplasms, Experimental Benzene 16.4311921183
MESH:D008325 Mammary Neoplasms, Experimental Drugs, Chinese Herbal 16.4314758024
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 16.4316891317 11807958 11408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Genistein 16.4314578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 16.438985016 11606380
MESH:D020149 Manganese Poisoning Estradiol 4.1219453300
MESH:D008527 Medulloblastoma Tretinoin 2.6417453147
MESH:D008545 Melanoma Curcumin 4.8017885582 18462866
MESH:D008545 Melanoma resveratrol 4.8017992120
MESH:D008545 Melanoma Tretinoin 4.8016752155
MESH:D008569 Memory Disorders Curcumin 9.0417263510
MESH:D008569 Memory Disorders icariin 9.0419782061
MESH:D008591 Meningomyelocele Tretinoin 4.0816940565
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.0418303189 16966607 16166281
MESH:D008659 Metabolic Diseases resveratrol 4.0617112576
MESH:D008881 Migraine Disorders montelukast 4.5710759916
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.1915863610
MESH:D009062 Mouth Neoplasms Tobacco Smoke Pollution 4.0815006635
MESH:D009101 Multiple Myeloma arsenic trioxide 25.0019417148 11468182 14977855 15949261 19549372
MESH:D009101 Multiple Myeloma Benzene 25.0017119195
MESH:D009101 Multiple Myeloma Curcumin 25.0019372569
MESH:D009101 Multiple Myeloma Raloxifene 25.0016497877
MESH:D009101 Multiple Myeloma resveratrol 25.0017049120 16267019 16490592 14749477 17935668 17164350
MESH:D009101 Multiple Myeloma Vitamin A 25.0016374440
MESH:D009134 Muscular Atrophy, Spinal Curcumin 11.2317962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 11.2317962980
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.3118349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 6.7116882451 16105982
MESH:D009190 Myelodysplastic Syndromes Tretinoin 6.7117596541
MESH:D009203 Myocardial Infarction Genistein 12.3817141266
MESH:D009203 Myocardial Infarction Hydrochloric Acid 12.3818534312
MESH:D009203 Myocardial Infarction Quercetin 12.3819595682
MESH:D009203 Myocardial Infarction resveratrol 12.3816317513 17015251 17125593 17188708 16456233 16525036
MESH:D017202 Myocardial Ischemia resveratrol 8.0917125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.0912213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 12.7316810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 12.7317141266
MESH:D015428 Myocardial Reperfusion Injury Quercetin 12.7319207477
MESH:D009205 Myocarditis resveratrol 4.4017322642
MESH:D009232 Myxoma Raloxifene 5.1916343187
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 9.2116624393
MESH:D009361 Neoplasm Invasiveness Curcumin 9.2118495463
MESH:D009369 Neoplasms Quercetin 4.6315185748
MESH:D009369 Neoplasms Tretinoin 4.6316594593 16946489
MESH:D009374 Neoplasms, Experimental resveratrol 3.668985016
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 4.1712497104
MESH:D009389 Neovascularization, Pathologic Estradiol 3.3817289903
MESH:D009421 Nervous System Malformations Estradiol 20.6711399458 16427766
MESH:D009421 Nervous System Malformations Genistein 20.6716427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 20.6714600291
MESH:D009421 Nervous System Malformations Tretinoin 20.679125849
MESH:D009423 Nervous System Neoplasms Curcumin 5.2718462866
MESH:D009436 Neural Tube Defects arsenic trioxide 15.5010525206
MESH:D009436 Neural Tube Defects Benzene 15.5015643154
MESH:D009436 Neural Tube Defects Tretinoin 15.509142499
MESH:D009436 Neural Tube Defects Vitamin A 15.5017400914
MESH:D019636 Neurodegenerative Diseases resveratrol 3.5217652729
MESH:D020078 Neurogenic Inflammation Quercetin 9.6117929310
MESH:D020078 Neurogenic Inflammation resveratrol 9.6117929310
MESH:D009765 Obesity Curcumin 2.6619297423
MESH:D009784 Occupational Diseases Benzene 8.6417178637 15612468 17479406 15576619 15935809 17119257 15727169 15913788 16737584
MESH:D009784 Occupational Diseases Hydrochloric Acid 8.6412378975
MESH:D010024 Osteoporosis Curcumin 15.1918719352
MESH:D010024 Osteoporosis Genistein 15.1919401787
MESH:D010024 Osteoporosis icariin 15.1918236786 19747809
MESH:D010024 Osteoporosis Raloxifene 15.1917882678 15775268 19059307
MESH:D015663 Osteoporosis, Postmenopausal Drugs, Chinese Herbal 27.9916548355
MESH:D015663 Osteoporosis, Postmenopausal Genistein 27.9916169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 27.9919495926
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 27.9915579764 17893378 15758505 17823083
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 27.9917513867
MESH:D010051 Ovarian Neoplasms arsenic trioxide 21.0916624393 19769630 12452020
MESH:D010051 Ovarian Neoplasms Benzene 21.0912562636
MESH:D010051 Ovarian Neoplasms Curcumin 21.0918462866 19020741
MESH:D010051 Ovarian Neoplasms Estradiol 21.0919401270
MESH:D010051 Ovarian Neoplasms Genistein 21.0919005980
MESH:D010051 Ovarian Neoplasms Quercetin 21.0919005980
MESH:D010051 Ovarian Neoplasms Tretinoin 21.0916936753
MESH:D010146 Pain montelukast 6.4715935457
MESH:D010146 Pain Tretinoin 6.4716870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 11.2515580305
MESH:D010190 Pancreatic Neoplasms Curcumin 11.2517440100 19196508 19401701
MESH:D010190 Pancreatic Neoplasms Quercetin 11.2516965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 11.2515976015
MESH:D010235 Paraganglioma arsenic trioxide 3.8419927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8912520081
MESH:D010391 Pemphigoid, Bullous Niacinamide 6.0911026799
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.5510923243
MESH:D011015 Pneumonia, Aspiration Hydrochloric Acid 5.0215970105 18497604 18573544 15607125
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2218163543
MESH:D011230 Precancerous Conditions Quercetin 3.6919056647
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 8.4116679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.4111222880 11118676 11399792 11896295
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.4215572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.5720887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.3619131511
MESH:D011471 Prostatic Neoplasms Calcitriol 2.3616644109 15754350 16289102 18247401 12479363
MESH:D011471 Prostatic Neoplasms Curcumin 2.3618769126 18226269 18156803 15129424 11398177 10851300 12497104
MESH:D011471 Prostatic Neoplasms Estradiol 2.3616740699
MESH:D011471 Prostatic Neoplasms Genistein 2.3615256057 15378649 16925846
MESH:D011471 Prostatic Neoplasms Quercetin 2.3614715546 17292933
MESH:D011471 Prostatic Neoplasms Raloxifene 2.3616536755 15731164 16220300
MESH:D011471 Prostatic Neoplasms resveratrol 2.3616731767 17675339 15767336 17636462 17718901 17804756
MESH:D011507 Proteinuria Tretinoin 3.2816636307
MESH:D011625 Pterygium Tretinoin 4.4416723453
MESH:D001261 Pulmonary Atelectasis Hydrochloric Acid 5.6520597076
MESH:D011654 Pulmonary Edema Hydrochloric Acid 4.8515090967
MESH:D011656 Pulmonary Emphysema Curcumin 4.2219168576
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 8.7717322281 17365031 15814490 17975199
MESH:D011658 Pulmonary Fibrosis Drugs, Chinese Herbal 8.7716987627
MESH:D011658 Pulmonary Fibrosis troglitazone 8.7718162602
MESH:D011693 Purpura Raloxifene 5.1915770314
MESH:D012003 Rectal Fistula Drugs, Chinese Herbal 5.6015043669
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.2216325855
MESH:D015427 Reperfusion Injury resveratrol 3.1016317513 17520802 15827377 16314181 17058453
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 8.5018379247 10666014
MESH:D012128 Respiratory Distress Syndrome, Adult Hydrochloric Acid 8.5018339021 16129981 16784557 17627322 18549715
MESH:D012127 Respiratory Distress Syndrome, Newborn Vitamin A 5.4516877224
MESH:D012133 Respiratory Paralysis Hydrochloric Acid 6.0011510729
MESH:D012135 Respiratory Sounds Tobacco Smoke Pollution 4.2818410779
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5018990726
MESH:D012140 Respiratory Tract Diseases Hydrochloric Acid 4.8120516732
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.7716116481 16283617
MESH:D012220 Rhinitis montelukast 4.8320332717
MESH:D012221 Rhinitis, Allergic, Perennial Drugs, Chinese Herbal 4.9115015336
MESH:D012509 Sarcoma Curcumin 3.8118462866
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.6216646077
MESH:D012554 Schistosomiasis japonica Quercetin 5.1816862918
MESH:D018805 Sepsis Curcumin 3.7918389075
MESH:D012871 Skin Diseases Vitamin A 3.2618709164
MESH:D012878 Skin Neoplasms resveratrol 12.208985016 15837718
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 12.2016192470
MESH:D012878 Skin Neoplasms Tobacco Smoke Pollution 12.2018590791
MESH:D012878 Skin Neoplasms Tretinoin 12.2016467112
MESH:D020181 Sleep Apnea, Obstructive montelukast 5.8019118273
MESH:D013119 Spinal Cord Injuries montelukast 5.4518059327
MESH:D013274 Stomach Neoplasms arsenic trioxide 6.0117007042
MESH:D013274 Stomach Neoplasms Benzene 6.0112562636
MESH:D013274 Stomach Neoplasms Drugs, Chinese Herbal 6.0118339527
MESH:D013274 Stomach Neoplasms Tretinoin 6.0117261132
MESH:D013274 Stomach Neoplasms troglitazone 6.0115930296
MESH:D013276 Stomach Ulcer Curcumin 10.6416631530 19188055
MESH:D013276 Stomach Ulcer Hydrochloric Acid 10.6415309881 17189318 16755016
MESH:D013276 Stomach Ulcer montelukast 10.6417895592
MESH:D018640 Stomatognathic System Abnormalities marker/mechanism 20357738
MESH:D020521 Stroke Raloxifene 3.5516837676
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.1716321402
MESH:D013345 Subarachnoid Hemorrhage Drugs, Chinese Herbal 5.4017634840
MESH:D013953 Thymus Neoplasms Benzene 4.6010850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5412697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 6.3219014326
MESH:D013964 Thyroid Neoplasms Tretinoin 6.3216026305 17045167
MESH:D013978 Tibial Fractures Estradiol 12.5119048282
MESH:D013978 Tibial Fractures Raloxifene 12.5119048282
MESH:D014062 Tongue Neoplasms resveratrol 8.8916227395
MESH:D014062 Tongue Neoplasms Tretinoin 8.8916051514
MESH:D014071 Tooth Abnormalities marker/mechanism 14688224
MESH:D016171 Torsades de Pointes arsenic trioxide 3.6115213294
MESH:D014376 Tuberculosis Tretinoin 3.0116040207
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 14.2820435036 12845720 12973940 11780464
MESH:D001749 Urinary Bladder Neoplasms Curcumin 14.2818593936
MESH:D001749 Urinary Bladder Neoplasms Quercetin 14.2816720314
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 14.2817572228
MESH:D001749 Urinary Bladder Neoplasms Tobacco Smoke Pollution 14.2812846360
MESH:D014565 Urogenital Neoplasms Curcumin 4.9118462866
MESH:D014581 Urticaria montelukast 4.8710982225
MESH:D002583 Uterine Cervical Neoplasms resveratrol 8.5217473185
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.5216129372
MESH:D014594 Uterine Neoplasms Benzene 8.7612562636
MESH:D014594 Uterine Neoplasms resveratrol 8.7617044934
MESH:D014604 Uveal Neoplasms Tretinoin 4.2516752155
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2312125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.8516837676
MESH:D018487 Ventricular Dysfunction, Left resveratrol 3.9617488730
MESH:D014802 Vitamin A Deficiency Vitamin A 4.9516175781 16960172 16146918
MESH:D014820 Vitiligo Tretinoin 3.7216761959
MESH:D014846 Vulvar Neoplasms Raloxifene 5.1916343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8915886252
MESH:D009396 Wilms Tumor Tretinoin 3.6716287080
MESH:D014947 Wounds and Injuries Drugs, Chinese Herbal 4.2516313111
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA34885
    • No data
    No data
    Releated drug ID Related drug Name
    PA451620teriparatide
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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