AutismKB 2.0

Annotation Detail for CADPS


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Basic Information Top
Gene Symbol:CADPS ( CADPS1,CAPS,CAPS1,KIAA1121 )
Gene Full Name: Ca++-dependent secretion activator
Band: 3p14.2
Quick LinksEntrez ID:8618; OMIM: 604667; Uniprot ID:CAPS1_HUMAN; ENSEMBL ID: ENSG00000163618; HGNC ID: 1426
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C014024 2,4,5,2',4',5'-hexachlorobiphenyl [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CADPS mRNAaffects cotreatment|decreases expression 16984957
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of CADPS mRNAaffects expression 21346803
C023035 3,4,5,3',4'-pentachlorobiphenyl [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CADPS mRNAaffects cotreatment|decreases expression 16984957
D010656 Phenylephrine Phenylephrine results in decreased expression of CADPS mRNAdecreases expression 18158353
D010795 Phthalic Acids Phthalic Acids results in increased expression of CADPS mRNAincreases expression 15728792
C025299 polyphenols polyphenols results in decreased expression of CADPS mRNAdecreases expression 16293270
D015032 Zinc Zinc results in increased expression of CADPS mRNAincreases expression 17074742
D019287 Zinc Sulfate Zinc Sulfate results in increased expression of CADPS mRNAincreases expression 17074742
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Zinc Sulfate 5.247265320
MESH:D000169 Acrodermatitis Zinc 5.7416889938 17190629 17202136
MESH:D018248 Adenoma, Liver Cell 3,4,5,3',4'-pentachlorobiphenyl 5.5716628245
MESH:D000544 Alzheimer Disease Zinc 2.8016410023 16580781 17119284 16325427
MESH:D000755 Anemia, Sickle Cell Zinc 5.1816916123
MESH:D000860 Anoxia Zinc Sulfate 5.367265320
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 4.3417460149
MESH:D001249 Asthma Zinc 3.0117085522
MESH:D001289 Attention Deficit Disorder with Hyperactivity Phthalic Acids 4.5220106747
MESH:D001919 Bradycardia Phenylephrine 4.8815306635
MESH:D001930 Brain Injuries Zinc 5.0017109824
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 1.7816705839
MESH:D002294 Carcinoma, Squamous Cell Zinc 2.9516543248
MESH:D006332 Cardiomegaly Phenylephrine 3.6515728586 16170337 11754973 11179087 17124262 17287366
MESH:D002318 Cardiovascular Diseases Zinc 3.8216936243
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 2.936135515
MESH:D018281 Cholangiocarcinoma 3,4,5,3',4'-pentachlorobiphenyl 5.2316628245
MESH:D003110 Colonic Neoplasms polyphenols 2.7016293270
MESH:D019465 Craniofacial Abnormalities 3,4,5,3',4'-pentachlorobiphenyl 3.4117686920
MESH:D019465 Craniofacial Abnormalities Zinc 3.4119302082
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.3218551238
MESH:D003920 Diabetes Mellitus Zinc 4.4216479319
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 4.3418551238 21346803
MESH:D056486 Drug-Induced Liver Injury polyphenols 4.3419370779
MESH:D004489 Edema, Cardiac 3,4,5,3',4'-pentachlorobiphenyl 6.1317686920
MESH:D004938 Esophageal Neoplasms Zinc 2.9116543248
MESH:D005756 Gastritis Zinc 5.1717241300
MESH:D006130 Growth Disorders Zinc 4.1017217573
MESH:D006330 Heart Defects, Congenital 3,4,5,3',4'-pentachlorobiphenyl 4.2917686920 20471113
MESH:D006333 Heart Failure Zinc 3.7417162251
MESH:D006335 Heart Injuries Zinc 6.1517074742
MESH:D016481 Helicobacter Infections Zinc 4.7917241300
MESH:D006527 Hepatolenticular Degeneration Zinc 12.3617276780
MESH:D006527 Hepatolenticular Degeneration Zinc Sulfate 12.3617063115
MESH:D006973 Hypertension Phenylephrine 3.158949925 12717712
MESH:D006984 Hypertrophy Phenylephrine 4.8012791704 18502941
MESH:D007022 Hypotension Zinc Sulfate 4.737265320
MESH:D007249 Inflammation polyphenols 3.1716366677
MESH:D007511 Ischemia Zinc 4.9416584753
MESH:D007674 Kidney Diseases Zinc 3.4416960431
MESH:D007676 Kidney Failure, Chronic Zinc 4.6616518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.1816705839
MESH:D016773 Leishmaniasis, Cutaneous Zinc Sulfate 4.4615237267
MESH:D008107 Liver Diseases polyphenols 2.8316698588
MESH:D008113 Liver Neoplasms 2,4,5,2',4',5'-hexachlorobiphenyl 5.3016835634 18644402
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 5.307678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.682876786 2876784 6135515
MESH:D008325 Mammary Neoplasms, Experimental Zinc 3.4412773700
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.207678174 18551238
MESH:D009369 Neoplasms 2,4,5,2',4',5'-hexachlorobiphenyl 3.768820588
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.6616049721
MESH:D011225 Pre-Eclampsia Zinc 4.3617114810
MESH:D011471 Prostatic Neoplasms Zinc 3.7816606632 16517595 16700911 12429649
MESH:D012162 Retinal Degeneration Zinc 4.3016584753
MESH:D012640 Seizures 2,6-dinitrotoluene 2.6918551238
MESH:D012852 Sinusitis Phenylephrine 5.047327846
MESH:D013705 Temporomandibular Joint Disorders polyphenols 5.6317997062
MESH:D014062 Tongue Neoplasms Zinc 4.6316543248
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.3716049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.6610091137
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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