Annotation Detail for PSMG1
Basic Information Top
| Gene Symbol: | PSMG1 ( C21LRP,DSCR2,LRPC21,PAC1 ) |
|---|---|
| Gene Full Name: | proteasome (prosome, macropain) assembly chaperone 1 |
| Band: | 21q22.2 |
| Quick Links | Entrez ID:8624; OMIM: 605296; Uniprot ID:PSMG1_HUMAN; ENSEMBL ID: ENSG00000183527; HGNC ID: 3043 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| No data |
| No data |
| Desease Name |
|---|
| inflammatory bowel disease |
| IMMUNE |
| Desease Name |
|---|
| Inflammatory bowel disease |
| Ankylosing spondylitis |
| No data |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of PSMG1 mRNA | affects expression | 17562736 |
| D016572 | Cyclosporine | Cyclosporine results in increased expression of PSMG1 mRNA | increases expression | 20106945 |
| D014501 | Uranium | Uranium affects the expression of PSMG1 mRNA | affects expression | 15672453 |
| C005460 | uranyl acetate | uranyl acetate affects the expression of PSMG1 mRNA | affects expression | 15672453 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 4.57 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.40 | 18445737 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.79 | 10977129 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Cyclosporine | 2.79 | 12371664 | |
| MESH:D002779 | Cholestasis | Cyclosporine | 3.21 | 19486331 | |
| MESH:D003093 | Colitis, Ulcerative | marker/mechanism | 20228799 | ||
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.67 | 19923254 19416960 18713872 16109766 12392966 11461765 19370779 18071297 11739529 16781746 15968718 14725611 12594235 19085960 19164858 11421492 11743745 17906064 10774834 17522070 16485898 12540782 16393943 11529661 17562736 11287661 19420014 16081117 15619225 12958197 2444490 10663392 14986274 12705907 14550746 19739265 16177239 12153990 10915739 16227642 11834606 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.82 | 19426721 | |
| MESH:D005234 | Fatty Liver | Cyclosporine | 3.28 | 19224547 | |
| MESH:D005355 | Fibrosis | Cyclosporine | 3.70 | 12168785 12639820 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.40 | 16983495 | |
| MESH:D005885 | Gingival Hyperplasia | Cyclosporine | 4.85 | 8708960 | |
| MESH:D006457 | Hemoglobinuria, Paroxysmal | Cyclosporine | 5.05 | 15720958 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.02 | 16870215 | |
| MESH:D006973 | Hypertension | Cyclosporine | 2.21 | 10903974 | |
| MESH:D007638 | Keratoconjunctivitis Sicca | Cyclosporine | 5.16 | 15604871 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 6.48 | 15629191 12587719 | |
| MESH:D007674 | Kidney Diseases | Cyclosporine | 6.48 | 18776723 10903974 8314463 | |
| MESH:D007680 | Kidney Neoplasms | Cyclosporine | 3.08 | 12371664 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.70 | 19460945 12587719 19784758 11587558 12969438 16610002 19014921 16611625 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.63 | 17185352 16871587 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.13 | 19513568 | |
| MESH:D008664 | Metal Metabolism, Inborn Errors | Cyclosporine | 5.51 | 16801185 | |
| MESH:D009402 | Nephrosis, Lipoid | Cyclosporine | 5.16 | 17954296 | |
| MESH:D009404 | Nephrotic Syndrome | Cyclosporine | 3.65 | 18481113 19348381 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.21 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.73 | 16870215 | |
| MESH:D011230 | Precancerous Conditions | Cyclosporine | 3.59 | 12371664 | |
| MESH:D011565 | Psoriasis | Cyclosporine | 2.33 | 16882103 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.44 | 10982225 | |
| MESH:D014605 | Uveitis | Cyclosporine | 4.71 | 1336536 | |
| MESH:D014985 | Xerophthalmia | Cyclosporine | 5.16 | 17120751 |
| No data |