AutismKB 2.0

Annotation Detail for SKAP1


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Basic Information Top
Gene Symbol:SKAP1 ( SCAP1,SKAP55 )
Gene Full Name: src kinase associated phosphoprotein 1
Band: 17q21.32
Quick LinksEntrez ID:8631; OMIM: 604969; Uniprot ID:SKAP1_HUMAN; ENSEMBL ID: ENSG00000141293; HGNC ID: 15605
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SKAP1 mRNAaffects expression 16483693
D008727 Methotrexate SKAP1 protein affects the susceptibility to Methotrexateaffects response to substance 16217747
D018038 Sodium Selenite Sodium Selenite results in increased expression of SKAP1 mRNAincreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Methotrexate 4.9812039119
MESH:D000138 Acidosis Ammonium Chloride 4.3018287403
MESH:D001172 Arthritis, Rheumatoid Methotrexate 3.1717286800
MESH:D001943 Breast Neoplasms Methotrexate 3.0616978400
MESH:D019457 Chromosome Breakage Sodium Selenite 5.4115894690
MESH:D019465 Craniofacial Abnormalities Methotrexate 2.679562676 12039119
MESH:D003550 Cystic Fibrosis Methotrexate 4.6819747007
MESH:D003882 Dermatomyositis Methotrexate 5.7120191521
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.1916285004
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 2.3715131321
MESH:D006086 Graft vs Host Disease Methotrexate 5.8016518429
MESH:D007333 Insulin Resistance Sodium Selenite 3.5414714311
MESH:D007805 Language Development Disorders Methotrexate 5.639562676
MESH:D008103 Liver Cirrhosis Methotrexate 3.9114986274
MESH:D017563 Lung Diseases, Interstitial Methotrexate 5.8918516814
MESH:D008223 Lymphoma Methotrexate 4.2617352296
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.5914737004
MESH:D052016 Mucositis Methotrexate 6.0217488658
MESH:D010051 Ovarian Neoplasms marker/mechanism 20852632
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.3318760546
MESH:D011565 Psoriasis Methotrexate 3.5517410198
MESH:D051437 Renal Insufficiency Methotrexate 5.3617352296
MESH:D013576 Syndactyly Methotrexate 5.629562676
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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