Annotation Detail for MAPKSP1
Basic Information Top
| Gene Symbol: | MAPKSP1 ( MAP2K1IP1,MAPBP,MP1 ) |
|---|---|
| Gene Full Name: | MAPK scaffold protein 1 |
| Band: | 4q23 |
| Quick Links | Entrez ID:8649; OMIM: 603296; Uniprot ID:MPKS1_HUMAN; ENSEMBL ID: ENSG00000109270; HGNC ID: |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Diseases/Disorders| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D003024 | Clozapine | Clozapine results in increased expression of LAMTOR3 mRNA | increases expression | 14647396 |
| D006220 | Haloperidol | Haloperidol results in increased expression of LAMTOR3 mRNA | increases expression | 14647396 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000380 | Agranulocytosis | Clozapine | 5.82 | 14617031 12649775 16160616 | |
| MESH:D001321 | Autistic Disorder | Haloperidol | 2.71 | 19368416 18080171 | |
| MESH:D002375 | Catalepsy | Haloperidol | 5.80 | 15215559 1977408 | |
| MESH:D003072 | Cognition Disorders | Clozapine | 5.73 | 17123785 | |
| MESH:D016757 | Death, Sudden, Cardiac | Haloperidol | 5.45 | 20210726 | |
| MESH:D003704 | Dementia | Haloperidol | 5.13 | 11575062 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Clozapine | 3.06 | 16402076 | |
| MESH:D006970 | Disorders of Excessive Somnolence | Clozapine | 6.62 | 15331141 | |
| MESH:D050171 | Dyslipidemias | Clozapine | 4.53 | 16402076 | |
| MESH:D006948 | Hyperkinesis | Clozapine | 5.79 | 16046005 | |
| MESH:D008064 | Lipidoses | Clozapine | 4.30 | 17567588 | |
| MESH:D001523 | Mental Disorders | Clozapine | 11.53 | 16856516 | |
| MESH:D001523 | Mental Disorders | Haloperidol | 11.53 | 16856516 | |
| MESH:D024821 | Metabolic Syndrome X | Clozapine | 4.85 | 19142101 | |
| MESH:D009765 | Obesity | Clozapine | 3.10 | 19142110 18515891 | |
| MESH:D011595 | Psychomotor Agitation | Haloperidol | 5.72 | 11575062 | |
| MESH:D011618 | Psychotic Disorders | Clozapine | 10.32 | 15331141 | |
| MESH:D011618 | Psychotic Disorders | Haloperidol | 10.32 | 11575062 | |
| MESH:D012559 | Schizophrenia | Clozapine | 4.27 | 20452607 17667964 20521326 16141801 20580759 19369910 18855531 18806925 17726453 17123785 20107430 20521320 11763009 11151749 20168265 | |
| MESH:D012559 | Schizophrenia | Haloperidol | 4.27 | 18513383 19369910 1830565 20107430 | |
| MESH:D017180 | Tachycardia, Ventricular | Haloperidol | 5.38 | 20210726 | |
| MESH:D015430 | Weight Gain | Clozapine | 4.94 | 20107430 20564506 17502770 16141801 20521320 16402076 | |
| MESH:D015431 | Weight Loss | Clozapine | 5.96 | 17933447 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:04010 | MAPK signaling pathway |