AutismKB 2.0

Annotation Detail for PDE5A


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Basic Information Top
Gene Symbol:PDE5A ( CGB-PDE,CN5A,PDE5 )
Gene Full Name: phosphodiesterase 5A, cGMP-specific
Band: 4q26
Quick LinksEntrez ID:8654; OMIM: 603310; Uniprot ID:PDE5A_HUMAN; ENSEMBL ID: ENSG00000138735; HGNC ID: 8784
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00230Purine metabolism
Pathway IDPathway Name
Hemostasis
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of PDE5A mRNAdecreases expression 19933214
C485966 ((3,4-(methylenedioxy)benzyl)amino)-6-chloroquinazoline ((3,4-(methylenedioxy)benzyl)amino)-6-chloroquinazoline results in decreased activity of PDE5A proteindecreases activity 16325476
C532608 3,7-bis(2-hydroxyethyl)icaritin 3,7-bis(2-hydroxyethyl)icaritin results in decreased activity of PDE5A proteindecreases activity 18778098
C439285 (5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride (5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride binds to and results in decreased activity of PDE5A proteinaffects binding|decreases activity 11602670
D006710 Homocysteine Homocysteine results in decreased expression of PDE5A mRNAdecreases expression 17326132
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PDE5A mRNAaffects expression 16483693
D000872 Anthocyanins Anthocyanins results in decreased activity of PDE5A proteindecreases activity 15769121
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of PDE5A mRNAaffects expression 20382639
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of PDE5A mRNAincreases expression 16644059
D004390 Chlorpyrifos Chlorpyrifos results in decreased expression of PDE5A mRNAdecreases expression 17452286
D003976 Diazinon Diazinon results in decreased expression of PDE5A mRNAdecreases expression 17452286
D004176 Dipyridamole Dipyridamole results in decreased activity of PDE5A proteindecreases activity 11051267
D004958 Estradiol Estradiol results in decreased expression of PDE5A mRNAdecreases expression 19429434
D005419 Flavonoids Flavonoids results in increased expression of PDE5A mRNAincreases expression 18035473
C056599 icariin icariin analog results in decreased activity of PDE5A proteindecreases activity 18778098
C056599 icariin icariin results in decreased activity of PDE5A proteindecreases activity 18778098
C056599 icariin icariin results in decreased expression of PDE5A mRNA alternative formdecreases expression 17120748
C065861 malvidin malvidin results in decreased activity of PDE5A proteindecreases activity 15769121
C458419 malvidin-3-glucoside malvidin-3-glucoside results in decreased activity of PDE5A proteindecreases activity 15769121
C052490 MY 5445 MY 5445 results in decreased activity of PDE5A proteindecreases activity 11051267
D009569 Nitric Oxide Nitric Oxide results in increased expression of PDE5A mRNAincreases expression 19374906
D009569 Nitric Oxide Nitric Oxide results in increased expression of PDE5A proteinincreases expression 19374906
D009569 Nitric Oxide PDE5A protein affects the susceptibility to Nitric Oxideaffects response to substance 19374906
D010656 Phenylephrine PDE5A protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]affects reaction|increases expression 18790048
D010656 Phenylephrine PDE5A protein affects the reaction [Phenylephrine results in increased expression of NPPB mRNA]affects reaction|increases expression 18790048
C058229 polydatin polydatin results in decreased activity of PDE5A proteindecreases activity 15769121
D020849 Raloxifene Raloxifene results in decreased expression of PDE5A mRNAdecreases expression 19429434
C059514 resveratrol resveratrol results in decreased activity of PDE5A proteindecreases activity 15769121
C101426 sildenafil sildenafil results in decreased activity of PDE5A proteindecreases activity 18778098
16368379
17138653
C101426 sildenafil sildenafil results in decreased activity of PDE5A proteindecreases activity 19374906
C101426 sildenafil sildenafil results in decreased activity of PDE5A proteindecreases activity 16325476
C025463 sulindac sulfone sulindac sulfone binds to and results in decreased activity of PDE5A proteinaffects binding|decreases activity 11602670
C025463 sulindac sulfone sulindac sulfone results in decreased activity of PDE5A proteindecreases activity 10910034
C429886 tadalafil tadalafil results in decreased activity of PDE5A proteindecreases activity 16368379
17138653
D013739 Testosterone Testosterone affects the expression of PDE5A mRNAaffects expression 17138653
D014108 Tosylphenylalanyl Chloromethyl Ketone Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of PDE5A mRNAdecreases expression 12466227
C426063 vardenafil vardenafil results in decreased activity of PDE5A proteindecreases activity 17138653
16368379
C011145 zaprinast zaprinast results in decreased activity of PDE5A proteindecreases activity 16325476
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.2818287403
MESH:D058186 Acute Kidney Injury resveratrol 3.6016538975
MESH:D000230 Adenocarcinoma Estradiol 2.0311473722
MESH:D000236 Adenoma resveratrol 3.1615688382
MESH:D011125 Adenomatous Polyposis Coli sulindac sulfone 5.0516150858
MESH:D000382 Agricultural Workers' Diseases Chlorpyrifos 8.2517119214 11874814 16611668
MESH:D000382 Agricultural Workers' Diseases Diazinon 8.2516487989
MESH:D000419 Albuminuria Raloxifene 4.3317308373 17451421
MESH:D000544 Alzheimer Disease icariin 9.0319858766 19782061
MESH:D000544 Alzheimer Disease Nitric Oxide 9.0317556102
MESH:D000544 Alzheimer Disease Raloxifene 9.0315800139
MESH:D000544 Alzheimer Disease resveratrol 9.0316183991 16162502
MESH:D000987 Antisocial Personality Disorder Testosterone 5.577506515
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.8717460149
MESH:D001169 Arthritis, Experimental resveratrol 7.5817115116
MESH:D001169 Arthritis, Experimental Tosylphenylalanyl Chloromethyl Ketone 7.5818706406
MESH:D050197 Atherosclerosis resveratrol 3.1117967414 16873680
MESH:D001321 Autistic Disorder Homocysteine 3.0716297937 20468076
MESH:D001847 Bone Diseases icariin 6.1318295595
MESH:D001919 Bradycardia Phenylephrine 4.2615306635
MESH:D001930 Brain Injuries Raloxifene 4.2016580743
MESH:D002545 Brain Ischemia icariin 9.8119303870
MESH:D002545 Brain Ischemia resveratrol 9.8117600658
MESH:D001943 Breast Neoplasms Estradiol 2.3012948864 18497071 17289903 16675129 14630087 17018787 17261762 19861407
MESH:D001943 Breast Neoplasms Nitric Oxide 2.3015631943
MESH:D001943 Breast Neoplasms Raloxifene 2.3015775269 17261762 17440819 15758505 17242785 15572757 17049068 16912660 16837676 17952589 17595753 17893378
MESH:D001943 Breast Neoplasms resveratrol 2.3017534123 17651959 16393696
MESH:D001943 Breast Neoplasms Testosterone 2.3017261762
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.1816111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.5110355542 15700767 3786805 15673190 16097048 16011737 16192424 15721981 16050911 16227642 18705752 16124888
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 4.3718788625
MESH:D006528 Carcinoma, Hepatocellular Estradiol 4.3716924424
MESH:D006528 Carcinoma, Hepatocellular resveratrol 4.3719321006 16227395
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.3116675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung sulindac sulfone 3.9918758305
MESH:D002294 Carcinoma, Squamous Cell resveratrol 2.6416227395
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 3.8317572228
MESH:D006332 Cardiomegaly Phenylephrine 3.3817124262 16170337 15728586 11754973 17287366 11179087
MESH:D009202 Cardiomyopathies sildenafil 4.9815811867
MESH:D002318 Cardiovascular Diseases Raloxifene 6.9315775269
MESH:D002318 Cardiovascular Diseases resveratrol 6.9315458977
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.0220889678
MESH:D002471 Cell Transformation, Neoplastic Estradiol 6.0218566989
MESH:D002659 Child Development Disorders, Pervasive Testosterone 3.5720678186
MESH:D002779 Cholestasis Nitric Oxide 4.2516919318
MESH:D003072 Cognition Disorders Raloxifene 4.3415800139
MESH:D003092 Colitis resveratrol 3.8616474422
MESH:D003110 Colonic Neoplasms resveratrol 2.4116338953
MESH:D015179 Colorectal Neoplasms resveratrol 3.1216550006
MESH:D015179 Colorectal Neoplasms sulindac sulfone 3.1210416599 18059344 10666051 11197048
MESH:D003324 Coronary Artery Disease Homocysteine 3.6616379339
MESH:D003327 Coronary Disease resveratrol 3.5716507316
MESH:D003550 Cystic Fibrosis sildenafil 5.1519747007
MESH:D015140 Dementia, Vascular Nitric Oxide 5.6817556102
MESH:D003865 Depressive Disorder, Major Raloxifene 3.9317474826
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.5516873680
MESH:D003928 Diabetic Nephropathies Estradiol 13.7419279558
MESH:D003928 Diabetic Nephropathies Raloxifene 13.7417308373 17451421 15920148
MESH:D003928 Diabetic Nephropathies resveratrol 13.7416286809
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 1.979327722 6623471 10915739 7120509 21278145 15998439 7440962 15027814 2869522 7179309 17522070 11566570 15968718 16227642 4309450 19085960 10092053 19336974 16177239 3732212 6884620 3786805
MESH:D004417 Dyspnea Diazinon 4.5216487989
MESH:D004487 Edema Raloxifene 6.4015860553
MESH:D004487 Edema resveratrol 6.408985016
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 8.5415845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 8.5417872969
MESH:D016889 Endometrial Neoplasms Estradiol 2.8018566989 11473722 19148513
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.5717923197
MESH:D007172 Erectile Dysfunction icariin 22.0516281085 15329286
MESH:D007172 Erectile Dysfunction sildenafil 22.0516368379
MESH:D007172 Erectile Dysfunction tadalafil 22.0516368379
MESH:D007172 Erectile Dysfunction vardenafil 22.0516368379
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.0020426865
MESH:D017889 Exfoliation Syndrome Homocysteine 5.4216504073
MESH:D005234 Fatty Liver Carbon Tetrachloride 7.1761145 12631006 19224547 12795759 17595544 15959796 16239168 16045604
MESH:D005234 Fatty Liver Raloxifene 7.1717473493
MESH:D005355 Fibrosis Carbon Tetrachloride 3.1818705752
MESH:D005391 Firesetting Behavior Testosterone 5.577506515
MESH:D005901 Glaucoma Homocysteine 5.0316504073
MESH:D005909 Glioblastoma Testosterone 3.8717162496
MESH:D006261 Headache Nitric Oxide 4.8911554966 11284996
MESH:D006330 Heart Defects, Congenital Homocysteine 3.8619638421
MESH:D006331 Heart Diseases Raloxifene 3.3511110106
MESH:D006505 Hepatitis Carbon Tetrachloride 8.7319900420 19110552
MESH:D006505 Hepatitis Diazinon 8.7316487989
MESH:D006558 Herpes Genitalis Estradiol 4.7515709030
MESH:D006561 Herpes Simplex resveratrol 3.9016876885
MESH:D006628 Hirsutism Testosterone 5.3717019078
MESH:D019584 Hot Flashes Estradiol 3.4717088409
MESH:D017588 Hyperandrogenism Testosterone 5.0217019078
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.2516899240
MESH:D006937 Hypercholesterolemia resveratrol 3.7617188708
MESH:D006940 Hyperemia Nitric Oxide 5.3311156591
MESH:D020138 Hyperhomocysteinemia Homocysteine 4.4718234410 17369066 17292331
MESH:D006949 Hyperlipidemias resveratrol 3.7716873680
MESH:D006973 Hypertension Phenylephrine 5.308949925 12717712
MESH:D006973 Hypertension Raloxifene 5.3017577099 15787275
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.8115338365
MESH:D006976 Hypertension, Pulmonary Nitric Oxide 4.2215838368
MESH:D006984 Hypertrophy Phenylephrine 4.3012791704 18502941
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.0617488730
MESH:D007006 Hypogonadism Testosterone 4.3912002444
MESH:D007018 Hypopituitarism Testosterone 5.9217426086
MESH:D007174 Impulse Control Disorders Testosterone 5.577506515
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.3717600658
MESH:D007248 Infertility, Male Diazinon 3.6412948887 16466525
MESH:D007249 Inflammation Flavonoids 4.8817296493
MESH:D007249 Inflammation resveratrol 4.8816366677
MESH:D007251 Influenza, Human resveratrol 4.2616624496
MESH:D007333 Insulin Resistance Estradiol 2.7916627594 16393666
MESH:D007410 Intestinal Diseases Nitric Oxide 4.6610210152 11713966 11574821
MESH:D007674 Kidney Diseases Estradiol 2.4315618244
MESH:D007680 Kidney Neoplasms Estradiol 2.7615610895
MESH:D007859 Learning Disorders icariin 5.0519782061
MESH:D007889 Leiomyoma Raloxifene 4.2416973256
MESH:D007896 Leishmaniasis Nitric Oxide 4.4217218153
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.4016087638
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.6617157831 16239168 16943688 11408273 21278145 17174718 16221502 17334410 11903743
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 2.3516033810 17823541 16015684 16638106 11481614 18395914 18418968 16136751 14724832 18251166 17976157 12649538 15876570 17869086 16011737 14748882 12445421 14716496 18420326 12586293 17640975 15123356 18395095 18472094 12609069 15673190 18187930 12741479 17766677 14620537 18006644 12546737 12389079 17721639 18054572 15730626 18263696 15818738 15959796 18205269 16027843 15931870 18166357 12666154 18705752 18339082 12958196 17481882 17944888 18376398 15925388 17922224 18156304 18277467 18429990 17557913 15052691 18279442 15057751 18210741 17698563 15370692 15893842 15338365 12445418 12898905 13678700 15362042 17631135 17714472 16116963 17805973 14716833 18412020 18317297 17761835 16192424 14512876 12632512 17708605 15650968 18472332 16097048 12632514 12667390 15996030 20821823 10355542 17525996 16248980 17900296 17565644 18481824
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 2.3514716833 14659978
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.1816964402 15830285 16246199 15720792 17285989
MESH:D008107 Liver Diseases Chlorpyrifos 4.1815991261
MESH:D017093 Liver Failure Carbon Tetrachloride 3.8915123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.4514706259 16899240
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 4.4019294768
MESH:D008113 Liver Neoplasms resveratrol 4.4019321006 19812893 20405173 19073162
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 2.4512014681 15583823
MESH:D055370 Lung Injury Nitric Oxide 4.4511395602
MESH:D008223 Lymphoma Nitric Oxide 4.0916166326
MESH:D016393 Lymphoma, B-Cell resveratrol 4.0417088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.6514749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 3.9715688416
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 5.5611408345 11807958 17203775 16891317
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 5.568985016 11606380
MESH:D020149 Manganese Poisoning Estradiol 4.2019453300
MESH:D008545 Melanoma resveratrol 2.3317992120
MESH:D008569 Memory Disorders icariin 5.0319782061
MESH:D008591 Meningomyelocele Homocysteine 5.2616602021
MESH:D008659 Metabolic Diseases resveratrol 4.1317112576
MESH:D008881 Migraine Disorders Nitric Oxide 4.0911701602
MESH:D020326 Migraine without Aura Nitric Oxide 4.8511304026 14659530
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.2715863610
MESH:D009101 Multiple Myeloma Raloxifene 6.8916497877
MESH:D009101 Multiple Myeloma resveratrol 6.8917935668 16490592 14749477 16267019 17164350 17049120
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.5917962980
MESH:D009203 Myocardial Infarction Homocysteine 5.9317412321
MESH:D009203 Myocardial Infarction resveratrol 5.9316525036 17125593 17188708 16456233 16317513 17015251
MESH:D017202 Myocardial Ischemia resveratrol 3.7917125593 17015251
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.0716810080
MESH:D009205 Myocarditis resveratrol 4.4817322642
MESH:D009232 Myxoma Raloxifene 5.2716343187
MESH:D009362 Neoplasm Metastasis marker/mechanism 12972520
MESH:D009374 Neoplasms, Experimental resveratrol 3.738985016
MESH:D009389 Neovascularization, Pathologic Estradiol 3.4517289903
MESH:D009421 Nervous System Malformations Estradiol 3.3911399458 16427766
MESH:D019636 Neurodegenerative Diseases resveratrol 3.5817652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.1417929310
MESH:D020258 Neurotoxicity Syndromes Chlorpyrifos 3.9815081274
MESH:D010024 Osteoporosis icariin 7.2618236786 19747809
MESH:D010024 Osteoporosis Raloxifene 7.2617882678 19059307 15775268
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 9.3517893378 17823083 15579764 15758505
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 9.3517513867
MESH:D010051 Ovarian Neoplasms Estradiol 2.1319401270
MESH:D010300 Parkinson Disease Homocysteine 3.4716275827
MESH:D011015 Pneumonia, Aspiration Nitric Oxide 5.0518573544
MESH:D011041 Poisoning Diazinon 4.1017603234
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 3.9016679765
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 10.0320887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Testosterone 10.0320887781
MESH:D011471 Prostatic Neoplasms Estradiol 2.2316740699
MESH:D011471 Prostatic Neoplasms Raloxifene 2.2316220300 16536755 15731164
MESH:D011471 Prostatic Neoplasms resveratrol 2.2316731767 17636462 17718901 17804756 15767336 17675339
MESH:D011471 Prostatic Neoplasms sulindac sulfone 2.2315570007 17908994
MESH:D011693 Purpura Raloxifene 5.2715770314
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.3016325855
MESH:D015427 Reperfusion Injury resveratrol 3.1416314181 16317513 17520802 17058453 15827377
MESH:D012135 Respiratory Sounds Chlorpyrifos 4.3617119214 16611668 11874814
MESH:D012140 Respiratory Tract Diseases Chlorpyrifos 4.6117119214 16611668
MESH:D012555 Schistosomiasis mansoni Nitric Oxide 5.189673227
MESH:D012559 Schizophrenia Homocysteine 3.0716641680
MESH:D012729 Sex Chromosome Aberrations Chlorpyrifos 5.816418539
MESH:D012735 Sexual Dysfunction, Physiological Testosterone 5.9216631401
MESH:D012852 Sinusitis Phenylephrine 4.427327846
MESH:D012878 Skin Neoplasms resveratrol 2.908985016 15837718
MESH:D013272 Stomach Diseases sildenafil 5.5616113693
MESH:D013276 Stomach Ulcer Nitric Oxide 3.9515138204
MESH:D020521 Stroke Raloxifene 3.6016837676
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.2416321402
MESH:D013978 Tibial Fractures Estradiol 12.7619048282
MESH:D013978 Tibial Fractures Raloxifene 12.7619048282
MESH:D014062 Tongue Neoplasms resveratrol 3.9716227395
MESH:D001748 Urinary Bladder Neck Obstruction vardenafil 7.7817138653
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 2.7117572228
MESH:D014570 Urologic Diseases Diazinon 4.9916487989
MESH:D002583 Uterine Cervical Neoplasms resveratrol 3.8617473185
MESH:D014594 Uterine Neoplasms resveratrol 3.8717044934
MESH:D054556 Venous Thromboembolism Raloxifene 4.9216837676
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.0317488730
MESH:D014846 Vulvar Neoplasms Raloxifene 5.2716343187
Pathway ID Pathway Name
REACT:604 Hemostasis
KEGG:00230 Purine metabolism
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA33132
  • No data
    Releated disease ID Related disease Name
    PA447321Depressive Disorder, Major
    Releated drug ID Related drug Name
    PA449233desipramine
    PA449673fluoxetine
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00203 antagonist Sildenafil Vasodilator Agents;Phosphodiesterase Inhibitors
    DB00277 antagonist Theophylline rougier elixir Vasodilator Agents;Phosphodiesterase Inhibitors;Bronchodilator Agents;Respiratory Smooth Muscle Relaxants
    DB00806 antagonist Pentoxifylline Free Radical Scavengers;Vasodilator Agents;Platelet Aggregation Inhibitors;Phosphodiesterase Inhibitors;Radiation-Protective Agents;Hematologic Agents;Hemorrheologic Agents
    DB00820 inhibitor Tadalafil Vasodilator Agents;Phosphodiesterase Inhibitors
    DB00862 antagonist Vardenafil Vasoconstrictor Agents;Phosphodiesterase Inhibitors;Anti-Impotence Agents
    DB00975 antagonist Dipyridamole Vasodilator Agents;Platelet Aggregation Inhibitors;Phosphodiesterase Inhibitors
    DB01972 - Guanosine-5'-Monophosphate
    DB03597 - Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine
    DB04272 - Citric Acid Anticoagulants;Chelating Agents
    DB06267 inhibitor Udenafil Vasodilator Agents;Phosphodiesterase Inhibitors
    DB07954 - 3-ISOBUTYL-1-METHYLXANTHINE
    DB08729 - 5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018