Annotation Detail for B4GALT3
Basic Information Top
| Gene Symbol: | B4GALT3 ( beta4Gal-T3 ) |
|---|---|
| Gene Full Name: | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 |
| Band: | 1q23.3 |
| Quick Links | Entrez ID:8703; OMIM: 604014; Uniprot ID:B4GT3_HUMAN; ENSEMBL ID: ENSG00000158850; HGNC ID: 926 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Diseases/Disorders| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of B4GALT3 mRNA | affects expression | 17562736 |
| D016572 | Cyclosporine | Cyclosporine results in increased expression of B4GALT3 mRNA | increases expression | 20106945 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 4.91 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.83 | 10977129 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Cyclosporine | 2.85 | 12371664 | |
| MESH:D002779 | Cholestasis | Cyclosporine | 3.28 | 19486331 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 19370779 12594235 17522070 11743745 19164858 11739529 19923254 10774834 16177239 18713872 17562736 19420014 16081117 15619225 16109766 12392966 11421492 12540782 2444490 14725611 16393943 11287661 15968718 11529661 16485898 18071297 19085960 14550746 12705907 11834606 19739265 10663392 12153990 14986274 12958197 17906064 16781746 16227642 11461765 19416960 10915739 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 5.17 | 19426721 | |
| MESH:D005234 | Fatty Liver | Cyclosporine | 3.40 | 19224547 | |
| MESH:D005355 | Fibrosis | Cyclosporine | 3.90 | 12168785 12639820 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.74 | 16983495 | |
| MESH:D005885 | Gingival Hyperplasia | Cyclosporine | 5.11 | 8708960 | |
| MESH:D006457 | Hemoglobinuria, Paroxysmal | Cyclosporine | 5.31 | 15720958 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.11 | 16870215 | |
| MESH:D006973 | Hypertension | Cyclosporine | 2.24 | 10903974 | |
| MESH:D007638 | Keratoconjunctivitis Sicca | Cyclosporine | 5.51 | 15604871 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 6.63 | 15629191 12587719 | |
| MESH:D007674 | Kidney Diseases | Cyclosporine | 6.63 | 8314463 10903974 18776723 | |
| MESH:D007680 | Kidney Neoplasms | Cyclosporine | 3.17 | 12371664 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 19460945 16611625 12969438 11587558 19784758 16610002 19014921 12587719 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.74 | 16871587 17185352 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.33 | 19513568 | |
| MESH:D008664 | Metal Metabolism, Inborn Errors | Cyclosporine | 5.86 | 16801185 | |
| MESH:D009402 | Nephrosis, Lipoid | Cyclosporine | 5.51 | 17954296 | |
| MESH:D009404 | Nephrotic Syndrome | Cyclosporine | 3.75 | 18481113 19348381 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.31 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.82 | 16870215 | |
| MESH:D011230 | Precancerous Conditions | Cyclosporine | 3.69 | 12371664 | |
| MESH:D011565 | Psoriasis | Cyclosporine | 2.35 | 16882103 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.58 | 10982225 | |
| MESH:D014605 | Uveitis | Cyclosporine | 5.05 | 1336536 | |
| MESH:D014985 | Xerophthalmia | Cyclosporine | 5.51 | 17120751 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:00533 | Glycosaminoglycan biosynthesis - keratan sulfate |
| KEGG:00601 | Glycosphingolipid biosynthesis - lacto and neolacto series |
| KEGG:01100 | Metabolic pathways |
| REACT:17015 | Metabolism of proteins |
| KEGG:00510 | N-Glycan biosynthesis |
| KEGG:00514 | Other types of O-glycan biosynthesis |
| Drugbank ID | Action | Drug Name | Description |
|---|---|---|---|
| DB00141 | - | N-Acetyl-D-glucosamine | Dietary supplement;Micronutrient |
| No data |
| No data |
| No data |