AutismKB 2.0

Annotation Detail for TNFRSF25


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Basic Information Top
Gene Symbol:TNFRSF25 ( APO-3,DDR3,DR3,LARD,TNFRSF12,TR3,TRAMP,WSL-1,WSL-LR )
Gene Full Name: tumor necrosis factor receptor superfamily, member 25
Band: 1p36.31
Quick LinksEntrez ID:8718; OMIM: 603366; Uniprot ID:TNR25_HUMAN; ENSEMBL ID: ENSG00000215788; HGNC ID: 11910
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04060Cytokine-cytokine receptor interaction
No data
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001151 Arsenic [Arsenic co-treated with Fluorides] results in decreased expression of TNFRSF25 mRNAaffects cotreatment|decreases expression 19962721
D001151 Arsenic Arsenic results in decreased expression of TNFRSF25 mRNAdecreases expression 19962721
C006632 arsenic trioxide arsenic trioxide results in decreased expression of TNFRSF25 mRNAdecreases expression 15761015
17530438
C006632 arsenic trioxide arsenic trioxide results in decreased expression of TNFRSF25 mRNAdecreases expression 19730151
C006780 bisphenol A bisphenol A results in decreased expression of TNFRSF25 mRNAdecreases expression 19371625
D003042 Cocaine Cocaine affects the expression of TNFRSF25 mRNAaffects expression 15681117
D004054 Diethylstilbestrol Diethylstilbestrol results in decreased expression of TNFRSF25 mRNAdecreases expression 19371625
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of TNFRSF25 mRNAincreases expression 16510352
D004317 Doxorubicin Doxorubicin results in decreased expression of TNFRSF25 mRNAdecreases expression 16705698
D004958 Estradiol Estradiol results in decreased expression of TNFRSF25 mRNAdecreases expression 19429434
D015025 Zearalenone Zearalenone results in decreased expression of TNFRSF25 mRNAdecreases expression 19371625
D005459 Fluorides [Arsenic co-treated with Fluorides] results in decreased expression of TNFRSF25 mRNAaffects cotreatment|decreases expression 19962721
D005459 Fluorides Fluorides results in decreased expression of TNFRSF25 mRNAdecreases expression 19962721
D005665 Furosemide Furosemide affects the expression of TNFRSF25 mRNAaffects expression 17497460
D019833 Genistein Genistein results in decreased expression of TNFRSF25 mRNAdecreases expression 19371625
C071834 glycidamide glycidamide results in increased expression of TNFRSF25 mRNAincreases expression 17822822
C031927 hydroquinone hydroquinone results in decreased expression of TNFRSF25 mRNAdecreases expression 15452088
D008345 Manganese Manganese results in increased expression of TNFRSF25 mRNAincreases expression 17175027
C025340 manganese chloride manganese chloride results in increased expression of TNFRSF25 mRNAincreases expression 17175027
D008769 Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in increased expression of TNFRSF25 mRNAincreases expression 12634122
C008493 methylselenic acid methylselenic acid results in increased expression of TNFRSF25 mRNAincreases expression 11830524
D020849 Raloxifene Raloxifene results in decreased expression of TNFRSF25 mRNAdecreases expression 19429434
D018038 Sodium Selenite Sodium Selenite results in decreased expression of TNFRSF25 mRNAdecreases expression 16705456
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of TNFRSF25 mRNAdecreases expression 18762178
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of TNFRSF25 mRNAincreases expression 15328365
C088658 zoledronic acid zoledronic acid results in decreased expression of TNFRSF25 mRNAdecreases expression 19036117
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.7411752688 14514962 15322242
MESH:D058186 Acute Kidney Injury zoledronic acid 4.3619715164
MESH:D000210 Acute-Phase Reaction zoledronic acid 5.3720200999
MESH:D000230 Adenocarcinoma arsenic trioxide 9.9819825857 11798837
MESH:D000230 Adenocarcinoma Doxorubicin 9.9817418594
MESH:D000230 Adenocarcinoma Estradiol 9.9811473722
MESH:D000230 Adenocarcinoma Genistein 9.9811473722
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.2716835633
MESH:D018246 Adrenocortical Adenoma Arsenic 5.1117306315
MESH:D000419 Albuminuria Doxorubicin 11.1021441931
MESH:D000419 Albuminuria Raloxifene 11.1017308373 17451421
MESH:D000544 Alzheimer Disease Raloxifene 2.5215800139
MESH:D000686 Amyloidosis Diethylstilbestrol 4.3715469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8511748828
MESH:D000756 Anemia, Sideroblastic Manganese 10.6916910769
MESH:D000756 Anemia, Sideroblastic manganese chloride 10.6916910769
MESH:D020261 Arsenic Poisoning Arsenic 2.8416835338 12569548 16251483 18414634
MESH:D050197 Atherosclerosis Arsenic 3.1819371607 12928151
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 8.6216206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.6212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6915746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.5914601052
MESH:D001859 Bone Neoplasms zoledronic acid 4.8516778634 16121404 17312309 19442620 11697798 15867366
MESH:D001862 Bone Resorption bisphenol A 9.4611985600
MESH:D001862 Bone Resorption zoledronic acid 9.468053405 15845617 18496637 16769263 11869084 18404659
MESH:D001930 Brain Injuries Raloxifene 4.3716580743
MESH:D001932 Brain Neoplasms Doxorubicin 3.7117150277
MESH:D001943 Breast Neoplasms bisphenol A 4.6517123778
MESH:D001943 Breast Neoplasms Diethylstilbestrol 4.6515324884 17129689
MESH:D001943 Breast Neoplasms Doxorubicin 4.6516595493 15692762 18382427 16322301 17983394 16826403 17369602 15993339 18628466 15939500 17426702 15994142 16115903 15136595 19526202 18695136 15567936 16264153 11325840 15634643 16935488 16096432 18234424 15668708
MESH:D001943 Breast Neoplasms Estradiol 4.6516675129 19861407 12948864 17261762 17018787 14630087 17289903 18497071
MESH:D001943 Breast Neoplasms Genistein 4.6517200150 16541309 16873071
MESH:D001943 Breast Neoplasms Raloxifene 4.6515758505 16912660 17440819 17242785 17261762 17595753 17049068 15775269 15572757 16837676 17952589 17893378
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 4.6520435547
MESH:D001943 Breast Neoplasms zoledronic acid 4.6518695136 16096432
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.2211589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.3516111702
MESH:D002276 Carcinoid Tumor Doxorubicin 4.7016051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7116835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.5315504454 17687452
MESH:D006528 Carcinoma, Hepatocellular Arsenic 11.1717306315 16507464
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 11.1711135700 14691202 16217749 15553829 15073043
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 11.1715948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 11.1716023760 16234567 18059187 17876044
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.1716924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 11.1716924424
MESH:D002278 Carcinoma in Situ bisphenol A 4.8817123778
MESH:D002289 Carcinoma, Non-Small-Cell Lung zoledronic acid 3.5019233551
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.7719014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 6.811485588 16201981
MESH:D002292 Carcinoma, Renal Cell zoledronic acid 6.8118507039
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.0212490120
MESH:D002294 Carcinoma, Squamous Cell Arsenic 4.8215504454 17687452 18922899
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 4.826189445
MESH:D002295 Carcinoma, Transitional Cell Arsenic 9.3418640142
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 9.3417572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3118670907 16120746 18850075
MESH:D009202 Cardiomyopathies Doxorubicin 3.4616612575 17924179 16242529 15505089 16455267 16651473 17329180 16952015 15811867 17928571 17007740 16364871 17308081 17351982 17974986 16269455 15476868 17519947 17382496 18627295 17131338 15792986 16109756 16731534 16278810
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.9117334414 16243910
MESH:D002318 Cardiovascular Diseases Arsenic 11.8119152805 17938729 15738583
MESH:D002318 Cardiovascular Diseases Genistein 11.8116332659
MESH:D002318 Cardiovascular Diseases Raloxifene 11.8115775269
MESH:D002340 Carotid Artery Diseases Arsenic 4.2116973168 18022660
MESH:D002471 Cell Transformation, Neoplastic Estradiol 6.8618566989
MESH:D002471 Cell Transformation, Neoplastic Methylnitronitrosoguanidine 6.862727394
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0716835633
MESH:D019457 Chromosome Breakage Sodium Selenite 4.6415894690
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0612621046 15340226 15668235 16354765 8697196
MESH:D019970 Cocaine-Related Disorders Cocaine 5.6119606084
MESH:D003072 Cognition Disorders Raloxifene 4.5115800139
MESH:D003110 Colonic Neoplasms Genistein 2.2717182828
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.5720501625
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.5718259882 18802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9617141729 14669216
MESH:D023903 Coronary Restenosis arsenic trioxide 4.0812609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.4410525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4420055451 15322242 10048152
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.4512952375 16002989
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.9915213294
MESH:D003865 Depressive Disorder, Major Raloxifene 4.0717474826
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.6816285004
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 4.2416647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.2417107852
MESH:D003928 Diabetic Nephropathies Estradiol 8.6919279558
MESH:D003928 Diabetic Nephropathies Raloxifene 8.6915920148 17308373 17451421
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 6.0817416283
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 6.0815131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.0820420201
MESH:D004362 Drug Toxicity Doxorubicin 7.8418602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.8411462148
MESH:D004417 Dyspnea Furosemide 4.8416935035
MESH:D004487 Edema Furosemide 11.0511834646
MESH:D004487 Edema Raloxifene 11.0515860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 11.0511000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8018230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 3.8915845917
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 11.5316402032
MESH:D004714 Endometrial Hyperplasia Genistein 11.5316402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 17.2315700306 16804899
MESH:D016889 Endometrial Neoplasms Doxorubicin 17.2317359293
MESH:D016889 Endometrial Neoplasms Estradiol 17.2319148513 18566989 11473722
MESH:D016889 Endometrial Neoplasms Genistein 17.2311473722
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.929294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.0518037988
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.2812903497
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9311564622
MESH:D005234 Fatty Liver arsenic trioxide 7.7015073043
MESH:D005234 Fatty Liver Raloxifene 7.7017473493
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.5915751030 16002989 16513791 16611131 16534752
MESH:D005264 Femoral Fractures zoledronic acid 5.7216234978
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3511858732
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.4819069698
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 2.8420067830
MESH:D005534 Foot Diseases Arsenic 5.456392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.1516904648
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.8416452187
MESH:D005909 Glioblastoma Doxorubicin 11.6417150277
MESH:D005909 Glioblastoma Genistein 11.6416598420
MESH:D005909 Glioblastoma Manganese 11.6417043766
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4910696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 3.4515692506
MESH:D034381 Hearing Loss Furosemide 4.7317868369
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2710048152 11294989
MESH:D006331 Heart Diseases Doxorubicin 7.5916244371 17875725 16144979 18006777 16879835 14766674 17888722 16244372 18674790 16495754 16330681 12587719 16707910
MESH:D006331 Heart Diseases Raloxifene 7.5911110106
MESH:D006333 Heart Failure Doxorubicin 7.3917481944
MESH:D006333 Heart Failure Furosemide 7.3916011733 16845234 12660669
MESH:D006394 Hemangiosarcoma Doxorubicin 3.8015692506
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2311000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.7812621046 15340226 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.9315709030
MESH:D006689 Hodgkin Disease Doxorubicin 3.3118501091 15147373 17606976
MESH:D019584 Hot Flashes Estradiol 3.6517088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9416959395 8697196 16354765 15340226 18606429
MESH:D006930 Hyperalgesia zoledronic acid 4.1616769263
MESH:D006934 Hypercalcemia Furosemide 10.9617652376
MESH:D006934 Hypercalcemia zoledronic acid 10.9618089816 19622757
MESH:D053565 Hypercalciuria Furosemide 5.5417652376
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.3617050553
MESH:D006962 Hyperparathyroidism, Secondary Furosemide 5.7715086907
MESH:D006965 Hyperplasia Diethylstilbestrol 4.3312960047 14722030
MESH:D006973 Hypertension Arsenic 8.4416076760 11953799 9931084
MESH:D006973 Hypertension Raloxifene 8.4415787275 17577099
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.4418670907 18850075
MESH:D046110 Hypertension, Pregnancy-Induced Furosemide 5.1816612254
MESH:D006987 Hypesthesia Arsenic 5.4516093927
MESH:D006996 Hypocalcemia zoledronic acid 6.0912669777
MESH:C537153 Hypomagnesemia primary Furosemide 5.5411041285
MESH:D007019 Hypoproteinemia Furosemide 5.7716096441
MESH:D007021 Hypospadias Diethylstilbestrol 4.4716002989
MESH:D007022 Hypotension Furosemide 4.5111041285
MESH:D007024 Hypotension, Orthostatic Furosemide 5.3115811171
MESH:D007246 Infertility Diethylstilbestrol 4.2515036965
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.8012200463 12878042
MESH:D007333 Insulin Resistance bisphenol A 11.9916393666
MESH:D007333 Insulin Resistance Estradiol 11.9916393666 16627594
MESH:D007333 Insulin Resistance Sodium Selenite 11.9914714311
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2316580747
MESH:D007642 Keratosis Arsenic 4.8816930632 12749816
MESH:D007674 Kidney Diseases Doxorubicin 9.9215369732 15699352 16775033
MESH:D007674 Kidney Diseases Estradiol 9.9215618244
MESH:D007674 Kidney Diseases Furosemide 9.9211041285
MESH:D007676 Kidney Failure, Chronic Doxorubicin 4.0516707910
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 7.2414681315 16762066 15003126
MESH:D007680 Kidney Neoplasms Estradiol 7.2415610895
MESH:D007859 Learning Disorders Diethylstilbestrol 3.9517184923
MESH:D007889 Leiomyoma Raloxifene 4.3916973256
MESH:D007938 Leukemia arsenic trioxide 6.2515070760
MESH:D007938 Leukemia Genistein 6.2517468513 18980019
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.0516085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 9.6317077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell zoledronic acid 9.6318089816
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.2016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3514633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.6619077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1217050201 16968895 20471514 16467208 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 7.5417339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.5416823087 15748426 11468182 16331271 17649720 17217047 16112521 16330433 19075265 17107899 16966277 15336539 9834237 19642359 15213294 12018890 16891316 17869043 17712046 19035177 12679006 11161223 19225113 12712474 15622746
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.2416882451
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 4.8616439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 4.8614716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 4.8617823541
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.8612878042
MESH:D008107 Liver Diseases Arsenic 2.5211134558
MESH:D008113 Liver Neoplasms Arsenic 10.4016368122
MESH:D008113 Liver Neoplasms arsenic trioxide 10.4014682389
MESH:D008113 Liver Neoplasms Diethylstilbestrol 10.4016712894 15890375
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 10.4016984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 9.4620377131
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 9.4617085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.4612151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.2615213294
MESH:D008175 Lung Neoplasms Arsenic 4.7719168569 17306315 17976673
MESH:D008175 Lung Neoplasms arsenic trioxide 4.7711798837 19825857
MESH:D008175 Lung Neoplasms Doxorubicin 4.776189445 17418594
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.7711884234 19555203
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.0415166399
MESH:D008223 Lymphoma Diethylstilbestrol 7.4815700306
MESH:D008223 Lymphoma Doxorubicin 7.4816098063
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 3.9514737004
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.7017654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.4615621674
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.4116002989
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 13.7615458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 13.7611807958 11408345 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental Genistein 13.7614578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental zoledronic acid 13.7617312309
MESH:D020149 Manganese Poisoning Estradiol 12.6519453300
MESH:D020149 Manganese Poisoning Manganese 12.6519453300 16568477 16551646
MESH:D008545 Melanoma Doxorubicin 2.2716827129
MESH:D008654 Mesothelioma Doxorubicin 6.5017638057
MESH:D008654 Mesothelioma zoledronic acid 6.5016675582
MESH:D053842 Microsatellite Instability Methylnitronitrosoguanidine 5.7817671175
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.4015792986
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.4515863610
MESH:D009069 Movement Disorders Manganese 4.9116551646
MESH:D052016 Mucositis Doxorubicin 4.6817415656
MESH:D009101 Multiple Myeloma arsenic trioxide 11.8219549372 19417148 11468182 14977855 15949261
MESH:D009101 Multiple Myeloma Raloxifene 11.8216497877
MESH:D009101 Multiple Myeloma zoledronic acid 11.8216996129 18089719 19621390
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.5718349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.0816882451 16105982
MESH:D009203 Myocardial Infarction Cocaine 9.4718072171
MESH:D009203 Myocardial Infarction Doxorubicin 9.4719429709 15857846
MESH:D009203 Myocardial Infarction Genistein 9.4717141266
MESH:D017202 Myocardial Ischemia Arsenic 8.7115371236
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.7112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.2316810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 8.2317141266
MESH:D009232 Myxoma Raloxifene 5.4516343187
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.8516624393
MESH:D009362 Neoplasm Metastasis Doxorubicin 6.1318259882
MESH:D009362 Neoplasm Metastasis zoledronic acid 6.1315867366 17312309 19139120
MESH:D009369 Neoplasms Diethylstilbestrol 2.7115313581
MESH:D009389 Neovascularization, Pathologic Estradiol 3.6217289903
MESH:D009397 Nephrocalcinosis Furosemide 5.7715086907
MESH:D009401 Nephrosis Doxorubicin 4.6616636307 16899518
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.9015640375 16889571
MESH:D009410 Nerve Degeneration Manganese 4.1916551646
MESH:D009421 Nervous System Malformations bisphenol A 29.6116427766 11399458
MESH:D009421 Nervous System Malformations Diethylstilbestrol 29.6111399458
MESH:D009421 Nervous System Malformations Estradiol 29.6116427766 11399458
MESH:D009421 Nervous System Malformations Genistein 29.6116427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 29.6114600291
MESH:D009436 Neural Tube Defects Arsenic 7.2116620997
MESH:D009436 Neural Tube Defects arsenic trioxide 7.2110525206
MESH:D009447 Neuroblastoma Doxorubicin 3.2115555623
MESH:D020078 Neurogenic Inflammation Arsenic 4.2717056641
MESH:D053206 Nocturnal Enuresis Furosemide 5.7717945291
MESH:D010014 Osteolysis zoledronic acid 5.2615867366
MESH:D010024 Osteoporosis Genistein 11.6519401787
MESH:D010024 Osteoporosis Raloxifene 11.6517882678 19059307 15775268
MESH:D010024 Osteoporosis zoledronic acid 11.6517882678
MESH:D015663 Osteoporosis, Postmenopausal Genistein 9.7916169203
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 9.7915579764 17893378 15758505 17823083
MESH:D012516 Osteosarcoma Doxorubicin 4.0215930896
MESH:D010049 Ovarian Diseases bisphenol A 4.8811985600
MESH:D010051 Ovarian Neoplasms Arsenic 11.0317306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 11.0316624393 19769630 12452020
MESH:D010051 Ovarian Neoplasms Estradiol 11.0319401270
MESH:D010051 Ovarian Neoplasms Genistein 11.0319005980
MESH:D010146 Pain zoledronic acid 3.8516475674
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.4915580305
MESH:D010235 Paraganglioma arsenic trioxide 4.0619927285
MESH:D010300 Parkinson Disease Manganese 3.3311181820
MESH:D020734 Parkinsonian Disorders Manganese 4.3716140633
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1412520081
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.0716093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.8815371236 16905509 6392382
MESH:D003557 Phyllodes Tumor Doxorubicin 5.0517983394
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.0614722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.5616977796 15687265
MESH:D010997 Pleural Neoplasms Doxorubicin 5.0517638057
MESH:D011141 Polyuria Furosemide 5.5417945291
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4518163543
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 15.6510548101
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 15.6517184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 15.6511118676 11896295 11222880 11399792
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 10.2120887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 10.2120887781
MESH:D011471 Prostatic Neoplasms Arsenic 4.2216140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 4.2219131511
MESH:D011471 Prostatic Neoplasms bisphenol A 4.2216740699
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 4.2217136230 15846301 15046698
MESH:D011471 Prostatic Neoplasms Doxorubicin 4.2215749863 15897917 16729912 16868541 16888761 18437689
MESH:D011471 Prostatic Neoplasms Estradiol 4.2216740699
MESH:D011471 Prostatic Neoplasms Genistein 4.2215256057 15378649 16925846
MESH:D011471 Prostatic Neoplasms methylselenic acid 4.2216205645
MESH:D011471 Prostatic Neoplasms Raloxifene 4.2216536755 16220300 15731164
MESH:D011471 Prostatic Neoplasms Sodium Selenite 4.2218760546
MESH:D011471 Prostatic Neoplasms zoledronic acid 4.2219103299 12438248
MESH:D011507 Proteinuria Arsenic 3.9021343184
MESH:D011618 Psychotic Disorders Cocaine 4.7416134406
MESH:D011629 Puberty, Precocious bisphenol A 4.6810548101
MESH:D011693 Purpura Raloxifene 5.4515770314
MESH:D051437 Renal Insufficiency Doxorubicin 4.1117922066
MESH:D015427 Reperfusion Injury Furosemide 3.8616526316
MESH:D012128 Respiratory Distress Syndrome, Adult Furosemide 4.5115912074 16096441 12394941
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7318990726
MESH:D012509 Sarcoma Doxorubicin 3.8917203757 16767912 18313854 15625365 17710206 15675481
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 16.7316646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 16.7314601052 16326096
MESH:D012512 Sarcoma, Ewing's zoledronic acid 16.7316121404
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.6817846226
MESH:D012640 Seizures Cocaine 3.9710454489
MESH:D012871 Skin Diseases Arsenic 2.7217453740 16759981 17548696 19834688 17050553 16353154 17938729 18709164 15952646 6392382 16702368
MESH:D012878 Skin Neoplasms Arsenic 9.2217976673 17029826 15504454 16251483 17050553 19538983
MESH:D012878 Skin Neoplasms Doxorubicin 9.2215692506
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.2216192470
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.4615625365 17203757 16767912
MESH:D013088 Spermatocele Diethylstilbestrol 4.6116002989 16709447
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.8217007042
MESH:D013274 Stomach Neoplasms Furosemide 2.8217052386
MESH:D020521 Stroke Raloxifene 3.7316837676
MESH:D019966 Substance-Related Disorders bisphenol A 3.8816045194 16684133
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8012697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 7.0519014326
MESH:D013964 Thyroid Neoplasms Doxorubicin 7.0516010429 17909728
MESH:D013978 Tibial Fractures Estradiol 13.3619048282
MESH:D013978 Tibial Fractures Raloxifene 13.3619048282
MESH:D016171 Torsades de Pointes arsenic trioxide 3.8515213294
MESH:D001749 Urinary Bladder Neoplasms Arsenic 15.3817306315 15987713 19322015 17976673 18640142 19429237 11144890
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 15.3811780464 20435036 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 15.3816712894 17306315 16452187
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 15.3817653716
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 15.3817572228
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 3.9416175088
MESH:D014591 Uterine Diseases bisphenol A 13.4614652134
MESH:D014591 Uterine Diseases Diethylstilbestrol 13.4614652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 3.9616690809 15809267
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.3316513791 16002989
MESH:D014652 Vascular Diseases Arsenic 4.6317056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4912125929
MESH:D054556 Venous Thromboembolism Raloxifene 5.1016837676
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.1117638931 17334414 17678736 16364871
MESH:D014846 Vulvar Neoplasms Raloxifene 5.4516343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1415886252
Pathway ID Pathway Name
KEGG:04060 Cytokine-cytokine receptor interaction
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA36603
    • No data
    Releated disease ID Related disease Name
    PA446329Motor Neuron Disease
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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