AutismKB 2.0

Annotation Detail for RIPK1


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Basic Information Top
Gene Symbol:RIPK1 ( FLJ39204,RIP,RIP1 )
Gene Full Name: receptor (TNFRSF)-interacting serine-threonine kinase 1
Band: 6p25.2
Quick LinksEntrez ID:8737; OMIM: 603453; Uniprot ID:RIPK1_HUMAN; ENSEMBL ID: ENSG00000137275; HGNC ID: 10019
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05160Hepatitis C
hsa04620Toll-like receptor signaling pathway
hsa04622RIG-I-like receptor signaling pathway
hsa04623Cytosolic DNA-sensing pathway
hsa04210Apoptosis
Pathway IDPathway Name
Apoptosis
Signaling in Immune system
Pathway IDPathway Name
200133HIV-1 Nef: Negative effector of Fas and TNF-alpha
200086TNF receptor signaling pathway
200067FAS (CD95) signaling pathway
200148Caspase cascade in apoptosis
200100Ceramide signaling pathway
200056TRAIL signaling pathway
200054Regulation of p38-alpha and p38-beta
Pathway IDPathway Name
P00006Apoptosis signaling pathway
Pathway IDPathway Name
500465TRAM Cascade
500256TNF signaling
500448Viral dsRNA:TLR3:TRIF Complex Activates RIP1
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of RIPK1 mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of RIPK1 mRNAincreases expression 18648102
D002108 Caerulein Caerulein results in increased cleavage of RIPK1 proteinincreases cleavage 16339139
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of RIPK1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RIPK1 mRNAaffects cotreatment|increases expression 17942748
D005665 Furosemide Furosemide affects the expression of RIPK1 mRNAaffects expression 17497460
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of RIPK1 mRNAaffects cotreatment|increases expression 17183730
C013592 mangiferin mangiferin results in decreased expression of RIPK1 mRNAdecreases expression 15135318
D015058 1-Naphthylisothiocyanate 1-Naphthylisothiocyanate results in increased expression of RIPK1 mRNAincreases expression 15913567
D015058 1-Naphthylisothiocyanate O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of RIPK1 mRNA]decreases reaction|increases expression 15913567
C107010 O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of RIPK1 mRNA]decreases reaction|increases expression 15913567
C059514 resveratrol resveratrol analog results in decreased expression of RIPK1 proteindecreases expression 15652768
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RIPK1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of RIPK1 mRNAincreases expression 15328365
12167310
15800033
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of RIPK1 mRNAaffects cotreatment|increases expression 17183730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.8314514962 11752688 15322242
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 8.838875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.0419490988
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.1217505938
MESH:D058186 Acute Kidney Injury resveratrol 3.9616538975
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8314692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 7.043712494
MESH:D000236 Adenoma resveratrol 7.0415688382
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.5316835633
MESH:D000544 Alzheimer Disease resveratrol 2.5916183991 16162502
MESH:D000550 Amblyopia Valproic Acid 5.4117688650
MESH:D000707 Anaphylaxis mangiferin 5.6116536907 14669257
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0511748828
MESH:D001008 Anxiety Disorders Valproic Acid 3.6617497229
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.6011256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.5815885639
MESH:D001169 Arthritis, Experimental resveratrol 7.5817115116
MESH:D050197 Atherosclerosis mangiferin 7.4118450471
MESH:D050197 Atherosclerosis resveratrol 7.4117967414 16873680
MESH:D001321 Autistic Disorder Valproic Acid 2.0016609825 19232924 18316065 17507914 17157402 18940202 18775368 18177632 17688650 18558336 18396377 19460635 15238991 18985861 20603192
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.191440618 11289319
MESH:D001714 Bipolar Disorder Valproic Acid 3.1320046352 17594078
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.1512125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.9615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 8.2515746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 8.258888407
MESH:D001862 Bone Resorption mangiferin 5.029881647
MESH:D002545 Brain Ischemia resveratrol 4.4417600658
MESH:D001943 Breast Neoplasms resveratrol 2.1317651959 17534123 16393696
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.1320435547
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8916835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 4.7216705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 4.727296757 3581430
MESH:D006528 Carcinoma, Hepatocellular resveratrol 4.7219321006 16227395
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.7516675471
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.727296757
MESH:D002294 Carcinoma, Squamous Cell resveratrol 2.7416227395
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4218850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases resveratrol 3.5515458977
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 2.837505956
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.7420734317
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.2616835633
MESH:D002761 Cholangitis 1-Naphthylisothiocyanate 6.3812912871
MESH:D002779 Cholestasis 1-Naphthylisothiocyanate 14.0612927374 15500046 18590720 18164287 7624871 15913567 16629650 19486331
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 14.0619486331 9022650
MESH:D002779 Cholestasis Ethinyl Estradiol 14.0616919318 15861022 17681005 17333356 16105132 11677210 17110522
MESH:D002780 Cholestasis, Intrahepatic 1-Naphthylisothiocyanate 6.0310220858 19407337
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1412621046 8697196 15668235 15340226 16354765
MESH:D003092 Colitis resveratrol 4.2716474422
MESH:D003110 Colonic Neoplasms resveratrol 2.4716338953
MESH:D015179 Colorectal Neoplasms resveratrol 2.2216550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1617141729 14669216
MESH:D003327 Coronary Disease resveratrol 3.8216507316
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.5020055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Valproic Acid 2.5016575769 17688650 8888407
MESH:D003457 Cryptosporidiosis mangiferin 6.0316547730
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.1518551238
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.948156756 8970840 11906362 11298694 2524372 12868966 14531868 18759878
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.612952479 3621924
MESH:D003921 Diabetes Mellitus, Experimental mangiferin 9.1819028559 12093613
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 9.1816873680
MESH:D003924 Diabetes Mellitus, Type 2 mangiferin 4.7811315760 9881663
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.7817107852
MESH:D003928 Diabetic Nephropathies mangiferin 9.8519706694 19960420
MESH:D003928 Diabetic Nephropathies resveratrol 9.8516286809
MESH:D056486 Drug-Induced Liver Injury 1-Naphthylisothiocyanate 15.697624871 18289764 20133375 17522070
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 15.6918551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 15.698291058 6679447 18692083 9328219 9653073 9022650 18289764 11289319 16192314 6482804 7440962 18648102 1440618
MESH:D056486 Drug-Induced Liver Injury O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate 15.6912540782
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 15.6920420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 15.691733752 19641884
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.8411462148
MESH:D004417 Dyspnea Furosemide 5.1116935035
MESH:D004421 Dystonia Valproic Acid 4.171851702
MESH:D004487 Edema Furosemide 12.2911834646
MESH:D004487 Edema resveratrol 12.298985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 12.2911000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.0818230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.5512538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 9.5517872969
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.129294722 10568697
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.9917923197
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.293659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 4.0916628512 3922381
MESH:D004827 Epilepsy Valproic Acid 2.9920417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.687562514 6426943 6254150
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.447750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.223659116
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.133581430
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0911564622
MESH:D005234 Fatty Liver Ethinyl Estradiol 13.9415345470
MESH:D005234 Fatty Liver mangiferin 13.9415975614
MESH:D005234 Fatty Liver Valproic Acid 13.9414986274 19224547
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5911858732
MESH:D005315 Fetal Diseases Valproic Acid 5.0616575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.268888407 18558336
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.196705139
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.0920067830
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.157505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.7710696789
MESH:D034381 Hearing Loss Furosemide 4.9317868369
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3810048152 11294989
MESH:D006331 Heart Diseases mangiferin 4.4612093613
MESH:D006333 Heart Failure Furosemide 4.1212660669 16011733 16845234
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.4411000095
MESH:D006505 Hepatitis 1-Naphthylisothiocyanate 10.0618590720
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 10.066705139
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.0315340226 12621046 16120746
MESH:D006561 Herpes Simplex mangiferin 10.7810715843
MESH:D006561 Herpes Simplex resveratrol 10.7816876885
MESH:D006849 Hydrocephalus Valproic Acid 5.0217688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.2215340226 16354765 8697196 16959395 18606429
MESH:D006934 Hypercalcemia Furosemide 5.1817652376
MESH:D053565 Hypercalciuria Furosemide 5.8117652376
MESH:D006937 Hypercholesterolemia resveratrol 4.1117188708
MESH:D006946 Hyperinsulinism mangiferin 5.099881663 11315760
MESH:D006949 Hyperlipidemias mangiferin 10.1415975614
MESH:D006949 Hyperlipidemias resveratrol 10.1416873680
MESH:D006962 Hyperparathyroidism, Secondary Furosemide 6.0515086907
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.0815034207
MESH:D006967 Hypersensitivity mangiferin 4.7916536907
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9418670907 18850075
MESH:D046110 Hypertension, Pregnancy-Induced Furosemide 12.2716612254
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 12.2716612254
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.4117488730
MESH:C537153 Hypomagnesemia primary Furosemide 5.8111041285
MESH:D007019 Hypoproteinemia Furosemide 6.0516096441
MESH:D007021 Hypospadias Ethinyl Estradiol 3.9516945680 16569931
MESH:D007022 Hypotension Furosemide 4.7311041285
MESH:D007024 Hypotension, Orthostatic Furosemide 5.5915811171
MESH:D007154 Immune System Diseases mangiferin 6.0316076520
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.7817600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.5812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5617937319
MESH:D007249 Inflammation mangiferin 8.8315222974
MESH:D007249 Inflammation resveratrol 8.8316366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 8.8312200463 12878042
MESH:D007251 Influenza, Human resveratrol 4.7216624496
MESH:D007333 Insulin Resistance mangiferin 4.4111315760
MESH:D007511 Ischemia mangiferin 5.4116806951
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.199022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.4416580747
MESH:D007674 Kidney Diseases Furosemide 7.1711041285
MESH:D007674 Kidney Diseases mangiferin 7.1712093613
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 7.6716705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 7.676582329
MESH:D007859 Learning Disorders mangiferin 5.0919182383
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive mangiferin 4.6915498116
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1717596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.6416087638
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.2615034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 1.2412878042
MESH:D008107 Liver Diseases 1-Naphthylisothiocyanate 3.2117184895
MESH:D008113 Liver Neoplasms resveratrol 4.7019073162 20405173 19321006 19812893
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.7016984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 5.953712494 598648 6587162 1399818
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 5.9512151625
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.4417228818
MESH:D008175 Lung Neoplasms mangiferin 2.7618816296 18520028 18569708
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.7611884234 19555203
MESH:D016393 Lymphoma, B-Cell resveratrol 4.4217088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.9614749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.4015688416
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 3.1811606380 8985016
MESH:D008545 Melanoma resveratrol 2.3817992120
MESH:D008569 Memory Disorders mangiferin 5.0619182383
MESH:D008659 Metabolic Diseases resveratrol 4.4917112576
MESH:D008881 Migraine Disorders Valproic Acid 3.2718765137 18803445
MESH:D009101 Multiple Myeloma resveratrol 3.5416267019 16490592 17164350 17049120 17935668 14749477
MESH:D009134 Muscular Atrophy, Spinal resveratrol 5.0217962980
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.148888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.2117596541
MESH:D009203 Myocardial Infarction mangiferin 6.5117052832 16584858 19172585 16697266 16538859
MESH:D009203 Myocardial Infarction resveratrol 6.5116456233 17125593 17188708 16317513 17015251 16525036
MESH:D017202 Myocardial Ischemia resveratrol 9.3117125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 9.3112213967
MESH:D009205 Myocarditis resveratrol 4.9117322642
MESH:D009336 Necrosis 2,4-dinitrotoluene 11.8018551238
MESH:D009336 Necrosis Caerulein 11.8015028970
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.513581430
MESH:D009374 Neoplasms, Experimental resveratrol 4.148985016
MESH:D009397 Nephrocalcinosis Furosemide 6.0515086907
MESH:D009410 Nerve Degeneration mangiferin 4.7017433543
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.3414600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.496679447
MESH:D009436 Neural Tube Defects Valproic Acid 7.4916359493 8888407
MESH:D019636 Neurodegenerative Diseases resveratrol 3.9017652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.5217929310
MESH:D053206 Nocturnal Enuresis Furosemide 6.0517945291
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 9.2312819281 16049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 9.234026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.193988306
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.3717513867
MESH:D010195 Pancreatitis Caerulein 5.9015028970 17948936
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.8011578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.627296757
MESH:D010300 Parkinson Disease mangiferin 3.7417433543
MESH:D010382 Peliosis Hepatis 1-Naphthylisothiocyanate 14.3820133375
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 14.3812520081
MESH:D010518 Periodontitis mangiferin 5.7819026997
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.646228378
MESH:D011141 Polyuria Furosemide 5.8117945291
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.6918163543
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 17.2116679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 17.2111222880 11896295 11399792 11118676
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 17.2120603192
MESH:D011471 Prostatic Neoplasms resveratrol 3.6215767336 17804756 16731767 17675339 17718901 17636462
MESH:D011537 Pruritus Ethinyl Estradiol 3.4715861022 16919318
MESH:D019310 Pseudolymphoma Valproic Acid 4.7112752131 11422049
MESH:D011833 Radiation Injuries, Experimental mangiferin 6.5815830843
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.7616325855
MESH:D015427 Reperfusion Injury Furosemide 7.3016526316
MESH:D015427 Reperfusion Injury resveratrol 7.3015827377 16314181 17058453 17520802 16317513
MESH:D012128 Respiratory Distress Syndrome, Adult Furosemide 4.7315912074 16096441 12394941
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.9618990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.463692021
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.2919155313
MESH:D012559 Schizophrenia Valproic Acid 2.0815737665 19110320
MESH:D012640 Seizures 2,4-dinitrotoluene 6.1918551238
MESH:D012640 Seizures Valproic Acid 6.191511512 11738929 14763951 17978042 3137016 11044598 16876388 15475178
MESH:D012772 Shock, Septic mangiferin 5.3915177305
MESH:D012878 Skin Neoplasms resveratrol 5.888985016 15837718
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.8816192470
MESH:D013088 Spermatocele Ethinyl Estradiol 4.1216709447
MESH:D016135 Spinal Dysraphism Valproic Acid 3.8619490988
MESH:D013226 Status Epilepticus Valproic Acid 4.7112833885
MESH:D013274 Stomach Neoplasms Furosemide 2.8617052386
MESH:D013276 Stomach Ulcer mangiferin 4.3817918041
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.5816321402
MESH:D013921 Thrombocytopenia 1-Naphthylisothiocyanate 4.8620133375
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.7411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2515669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.0812697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 2.973712494 6587162 7505956 6582329 1399818
MESH:D014062 Tongue Neoplasms resveratrol 4.3116227395
MESH:D014178 Translocation, Genetic Valproic Acid 5.4117262798
MESH:D014235 Trichinellosis mangiferin 6.2314669257
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.673119515
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 5.1416049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 5.148074119
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.788888407
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.4710091137
MESH:D002583 Uterine Cervical Neoplasms resveratrol 4.2017473185
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.9314692618
MESH:D014594 Uterine Neoplasms resveratrol 9.9317044934
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.7712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.6515869587 14671159
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.4417488730
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.4215886252
Pathway ID Pathway Name
KEGG:04210 Apoptosis
REACT:578 Apoptosis
KEGG:04623 Cytosolic DNA-sensing pathway
KEGG:05160 Hepatitis C
REACT:25035 Innate immune response mediated by toll like receptors
KEGG:04622 RIG-I-like receptor signaling pathway
REACT:6900 Signaling in Immune system
KEGG:04620 Toll-like receptor signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA34394
    • No data
    No data
    Releated drug ID Related drug Name
    PA449780glutathione
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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