AutismKB 2.0

Annotation Detail for RIPK2


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Basic Information Top
Gene Symbol:RIPK2 ( CARD3,CARDIAK,CCK,GIG30,RICK,RIP2 )
Gene Full Name: receptor-interacting serine-threonine kinase 2
Band: 8q21.3
Quick LinksEntrez ID:8767; OMIM: 603455; Uniprot ID:RIPK2_HUMAN; ENSEMBL ID: ENSG00000104312; HGNC ID: 10020
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04621NOD-like receptor signaling pathway
hsa05131Shigellosis
hsa04722Neurotrophin signaling pathway
Pathway IDPathway Name
Signalling by NGF
Signaling in Immune system
Pathway IDPathway Name
200034IL12-mediated signaling events
200026Canonical NF-kappaB pathway
200103p75(NTR)-mediated signaling
No data
Pathway IDPathway Name
500482Downstream TCR signaling
500614p75NTR recruits signalling complexes
Related Diseases/Disorders Top
No data
No data
Desease Name
Leprosy
NEUROLOGICAL
INFECTION
Cognitive performance
Desease Name
Cognitive test performance
Leprosy
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of RIPK2 mRNAincreases expression 18648102
C010643 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Cholesterol analog results in increased expression of RIPK2 mRNA]decreases reaction|increases expression 19477266
D000111 Acetylcysteine Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of RIPK2 mRNA]decreases reaction|increases expression 19477266
D001374 Azacitidine Azacitidine results in increased expression of RIPK2 mRNAincreases expression 15547111
C006780 bisphenol A bisphenol A results in decreased expression of RIPK2 mRNAdecreases expression 20678512
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of RIPK2 mRNAincreases expression 15336504
D002784 Cholesterol 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Cholesterol analog results in increased expression of RIPK2 mRNA]decreases reaction|increases expression 19477266
D002784 Cholesterol Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of RIPK2 mRNA]decreases reaction|increases expression 19477266
D002784 Cholesterol Cholesterol analog results in increased expression of RIPK2 mRNAincreases expression 19477266
D016572 Cyclosporine Cyclosporine results in increased expression of RIPK2 mRNAincreases expression 20106945
D019259 Lamivudine [Zidovudine co-treated with Lamivudine] results in increased expression of RIPK2 mRNAaffects cotreatment|increases expression 15784690
D002117 Calcitriol Calcitriol results in increased expression of RIPK2 mRNAincreases expression 16002434
D004317 Doxorubicin RIPK2 protein affects the susceptibility to Doxorubicinaffects response to substance 16217747
D004391 Dust Dust results in increased expression of RIPK2 mRNAincreases expression 17805423
D004958 Estradiol Estradiol affects the expression of RIPK2 mRNAaffects expression 14699072
D004958 Estradiol Estradiol inhibits the reaction [Etoposide results in increased expression of RIPK2 mRNA]decreases reaction|increases expression 19426747
D005047 Etoposide Estradiol inhibits the reaction [Etoposide results in increased expression of RIPK2 mRNA]decreases reaction|increases expression 19426747
D005047 Etoposide Etoposide results in increased expression of RIPK2 mRNAincreases expression 19426747
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of RIPK2 mRNAincreases expression 20423518
D008070 Lipopolysaccharides phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of RIPK2 mRNA]decreases reaction|increases expression 20423518
C058305 phenethyl isothiocyanate phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of RIPK2 mRNA]decreases reaction|increases expression 20423518
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of RIPK2 mRNAaffects binding|increases activity|increases expression 19710929
D019772 Topotecan RIPK2 protein affects the susceptibility to Topotecanaffects response to substance 16217747
D015215 Zidovudine [Zidovudine co-treated with Lamivudine] results in increased expression of RIPK2 mRNAaffects cotreatment|increases expression 15784690
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 4.769612607
MESH:D055371 Acute Lung Injury Lipopolysaccharides 8.8311850527 18653653
MESH:D055371 Acute Lung Injury pirinixic acid 8.8318653653
MESH:D000230 Adenocarcinoma Doxorubicin 4.4417418594
MESH:D000230 Adenocarcinoma Estradiol 4.4411473722
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.713712494
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.4216434500
MESH:D000419 Albuminuria Doxorubicin 4.4821441931
MESH:D050197 Atherosclerosis Cholesterol 4.2016632123
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.961440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.0819483382
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 11.9714601052
MESH:D019046 Bone Marrow Neoplasms Etoposide 11.9714601052
MESH:D001862 Bone Resorption bisphenol A 3.8011985600
MESH:D001932 Brain Neoplasms Doxorubicin 3.7517150277
MESH:D001943 Breast Neoplasms bisphenol A 2.3417123778
MESH:D001943 Breast Neoplasms Calcitriol 2.3411237771
MESH:D001943 Breast Neoplasms Doxorubicin 2.3418628466 17983394 18234424 15668708 16264153 16935488 18695136 15994142 15939500 16115903 19526202 15993339 16096432 16595493 17369602 18382427 15634643 11325840 15692762 15567936 16826403 17426702 16322301 15136595
MESH:D001943 Breast Neoplasms Estradiol 2.3412948864 14630087 17261762 16675129 17289903 18497071 19861407 17018787
MESH:D001943 Breast Neoplasms Etoposide 2.3416322251
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.4016111702
MESH:D002276 Carcinoid Tumor Doxorubicin 4.7516051944
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 4.563581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 4.5616234567 17876044 16023760 18059187
MESH:D006528 Carcinoma, Hepatocellular Estradiol 4.5616924424
MESH:D002278 Carcinoma in Situ bisphenol A 4.9317123778
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 6.457296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 6.4516201981 1485588
MESH:D002294 Carcinoma, Squamous Cell Acetylcysteine 7.6417015178
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 7.6411237771
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 7.646189445
MESH:D009202 Cardiomyopathies Doxorubicin 3.4816109756 17308081 17974986 16364871 15792986 17131338 16455267 15476868 17928571 16731534 15505089 17329180 17351982 17519947 16269455 16651473 16242529 16952015 16278810 17924179 17382496 15811867 17007740 16612575 18627295
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.9216243910 17334414
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 15.687505956
MESH:D002471 Cell Transformation, Neoplastic Acetylcysteine 15.6818226522
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 15.6812371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 15.6818566989
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 13.0919486331 9022650
MESH:D002779 Cholestasis Cyclosporine 13.0919486331
MESH:D002779 Cholestasis pirinixic acid 13.0919176532
MESH:D003093 Colitis, Ulcerative phenethyl isothiocyanate 3.6220423518
MESH:D015179 Colorectal Neoplasms Azacitidine 2.9019934284
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.9018802399 18259882
MESH:D003550 Cystic Fibrosis Acetylcysteine 4.3119747007
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.7411906362 12868966 11298694 2524372 8970840 8156756 14531868 18759878
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3918249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.433621924 2952479
MESH:D003928 Diabetic Nephropathies Estradiol 3.3519279558
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 6.329328219 1440618 9022650 18289764 11289319 7440962 18648102 16192314 18692083 6679447 6482804 8291058 9653073
MESH:D056486 Drug-Induced Liver Injury Acetylcysteine 6.3211287661
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 6.3217416283
MESH:D004362 Drug Toxicity Doxorubicin 13.7118602426
MESH:D004362 Drug Toxicity Lamivudine 13.7115040536
MESH:D004362 Drug Toxicity Zidovudine 13.7115040536
MESH:D004487 Edema pirinixic acid 2.4212083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 3.8715138306
MESH:D016889 Endometrial Neoplasms Doxorubicin 7.3917359293
MESH:D016889 Endometrial Neoplasms Estradiol 7.3911473722 19148513 18566989
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.1018037988
MESH:D019446 Endotoxemia Lipopolysaccharides 4.3317637181 15821434 15328337
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.093581430
MESH:D005234 Fatty Liver Cyclosporine 12.7919224547
MESH:D005234 Fatty Liver pirinixic acid 12.7919236843 20131406
MESH:D005234 Fatty Liver Zidovudine 12.7918299183
MESH:D005334 Fever Lipopolysaccharides 3.959205823 11852909
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.966705139
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.5319069698
MESH:D005355 Fibrosis Cyclosporine 3.0812168785 12639820
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.168708960
MESH:D005909 Glioblastoma Doxorubicin 3.3117150277
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.977505956
MESH:D006258 Head and Neck Neoplasms Doxorubicin 3.4815692506
MESH:D006331 Heart Diseases Doxorubicin 3.4416244372 16244371 18674790 16330681 14766674 16707910 16144979 17888722 16879835 12587719 17875725 18006777 16495754
MESH:D006333 Heart Failure Doxorubicin 6.9117481944
MESH:D006333 Heart Failure pirinixic acid 6.9120558911
MESH:D006394 Hemangiosarcoma Doxorubicin 3.8415692506
MESH:D006402 Hematologic Diseases Zidovudine 4.6512579204
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3615720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.3216366002
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.456705139
MESH:D006509 Hepatitis B Lamivudine 5.0417703166
MESH:D019694 Hepatitis B, Chronic Lamivudine 5.0412044531 16476009 15309715 15631357 15274664
MESH:D006529 Hepatomegaly pirinixic acid 2.9319176532 18467677 19772884 16221962
MESH:D006558 Herpes Genitalis Estradiol 4.9815709030
MESH:D006561 Herpes Simplex Etoposide 4.5010809021
MESH:D015658 HIV Infections Lamivudine 6.9420032539 9296927 11141242 17530837
MESH:D015658 HIV Infections Zidovudine 6.9411141242 11363243 17358032 11698656 20032539
MESH:D006689 Hodgkin Disease Doxorubicin 7.5518501091 17606976 15147373
MESH:D006689 Hodgkin Disease Etoposide 7.5516135485 17606976 15147373 16200630 18180244
MESH:D019584 Hot Flashes Estradiol 3.7017088409
MESH:D006937 Hypercholesterolemia Cholesterol 4.9116933029
MESH:D006943 Hyperglycemia pirinixic acid 3.1220558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.8815034207
MESH:D006973 Hypertension Cyclosporine 2.0710903974
MESH:D007249 Inflammation Lipopolysaccharides 2.8412878042 9205823 17237260 17255318 17963957
MESH:D007333 Insulin Resistance bisphenol A 12.0616393666
MESH:D007333 Insulin Resistance Estradiol 12.0616393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 12.0616306350
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.5717255318
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.969022650 8074119
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3915604871
MESH:D007674 Kidney Diseases Cyclosporine 9.878314463 18776723 10903974
MESH:D007674 Kidney Diseases Doxorubicin 9.8715369732 15699352 16775033
MESH:D007674 Kidney Diseases Estradiol 9.8715618244
MESH:D007676 Kidney Failure, Chronic Doxorubicin 4.0916707910
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 17.326582329
MESH:D007680 Kidney Neoplasms Cyclosporine 17.3212371664
MESH:D007680 Kidney Neoplasms Estradiol 17.3215610895
MESH:D007680 Kidney Neoplasms Zidovudine 17.3212579204
MESH:D007859 Learning Disorders Cholesterol 5.0317134702
MESH:D007938 Leukemia Azacitidine 3.6619148494
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.1016085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 4.3520370541
MESH:D007951 Leukemia, Myeloid Azacitidine 4.5619077051
MESH:D015470 Leukemia, Myeloid, Acute Azacitidine 2.9917596541 18720364
MESH:D054429 Leukemia, Myelomonocytic, Juvenile Azacitidine 5.1319299654
MESH:D007970 Leukopenia Lipopolysaccharides 4.6415821434
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.1515034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 4.9216595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 4.9214659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 4.9212878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.9215474484
MESH:D008113 Liver Neoplasms pirinixic acid 1.8020007298 16377806 15890375
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 5.92598648 6587162 1399818 3712494
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 5.9216842330 17085340
MESH:D008171 Lung Diseases Acetylcysteine 4.0112815614
MESH:D055370 Lung Injury Lipopolysaccharides 3.9421114838
MESH:D008175 Lung Neoplasms Azacitidine 3.6821224363
MESH:D008175 Lung Neoplasms Doxorubicin 3.686189445 17418594
MESH:D008175 Lung Neoplasms Zidovudine 3.6818800350
MESH:D008223 Lymphoma Doxorubicin 7.7516098063
MESH:D008223 Lymphoma Etoposide 7.7512556972 12854902
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.7317654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.5015621674
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 5.9815458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 5.9817203775 11408345 16891317 11807958
MESH:D020149 Manganese Poisoning Estradiol 4.4319453300
MESH:D008545 Melanoma 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid 4.0117992120
MESH:D008545 Melanoma Doxorubicin 4.0116827129
MESH:D008654 Mesothelioma Doxorubicin 3.0317638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7316801185
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 5.7817358032
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.4415792986
MESH:D009006 Monosomy Azacitidine 6.0319299654
MESH:D052016 Mucositis Doxorubicin 4.7317415656
MESH:D009101 Multiple Myeloma Azacitidine 3.9219549372 18443271
MESH:D009135 Muscular Diseases pirinixic acid 3.4416239165
MESH:D009190 Myelodysplastic Syndromes Azacitidine 3.9617596541 18720364 17611569 19805378
MESH:D009203 Myocardial Infarction Doxorubicin 5.6215857846 19429709
MESH:D009203 Myocardial Infarction pirinixic acid 5.6219151258
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.0816810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.0816411023
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 9.503581430
MESH:D009362 Neoplasm Metastasis Acetylcysteine 9.5014720322
MESH:D009362 Neoplasm Metastasis Doxorubicin 9.5018259882
MESH:D009369 Neoplasms pirinixic acid 1.9217405874
MESH:D009389 Neovascularization, Pathologic Estradiol 3.6717289903
MESH:D009401 Nephrosis Doxorubicin 4.7016636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3917954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 9.1019348381 18481113
MESH:D009404 Nephrotic Syndrome Doxorubicin 9.1015640375 16889571
MESH:D009421 Nervous System Malformations bisphenol A 9.5311399458 16427766
MESH:D009421 Nervous System Malformations Estradiol 9.5311399458 16427766
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.446679447
MESH:D009436 Neural Tube Defects Acetylcysteine 7.4419446573
MESH:D009447 Neuroblastoma Doxorubicin 7.1815555623
MESH:D009447 Neuroblastoma Topotecan 7.1815176712
MESH:D052556 Niemann-Pick Disease, Type C Cholesterol 5.6420557099 9802331
MESH:D009765 Obesity pirinixic acid 1.8020558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.366482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.963988306
MESH:D012516 Osteosarcoma Doxorubicin 4.0615930896
MESH:D010049 Ovarian Diseases bisphenol A 4.9311985600
MESH:D010051 Ovarian Neoplasms Estradiol 2.2019401270
MESH:D010190 Pancreatic Neoplasms Etoposide 3.2519003803
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.427296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.416228378
MESH:D003557 Phyllodes Tumor Doxorubicin 5.1017983394
MESH:D010997 Pleural Neoplasms Doxorubicin 5.1017638057
MESH:D011014 Pneumonia Lipopolysaccharides 4.4911605937 12224865
MESH:D011230 Precancerous Conditions Cyclosporine 3.1612371664
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 3.8910548101
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.7215572423
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 10.3520887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 10.3520887781
MESH:D011471 Prostatic Neoplasms Azacitidine 1.9018324645
MESH:D011471 Prostatic Neoplasms bisphenol A 1.9016740699
MESH:D011471 Prostatic Neoplasms Calcitriol 1.9018247401 16289102 16644109 12479363 15754350
MESH:D011471 Prostatic Neoplasms Doxorubicin 1.9016868541 15897917 16888761 16729912 18437689 15749863
MESH:D011471 Prostatic Neoplasms Estradiol 1.9016740699
MESH:D011471 Prostatic Neoplasms Etoposide 1.9017172428
MESH:D011565 Psoriasis Cyclosporine 2.2116882103
MESH:D011629 Puberty, Precocious bisphenol A 4.7210548101
MESH:D051437 Renal Insufficiency Doxorubicin 4.1617922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.3519058328
MESH:D012128 Respiratory Distress Syndrome, Adult Acetylcysteine 4.4612210543
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.6910835634
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.323692021
MESH:D012206 Rhabdomyolysis Lamivudine 5.479296927
MESH:D012509 Sarcoma Doxorubicin 3.9317203757 15625365 18313854 17710206 15675481 16767912
MESH:D012512 Sarcoma, Ewing's Doxorubicin 10.3416326096 14601052
MESH:D012512 Sarcoma, Ewing's Etoposide 10.3414601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.7317846226
MESH:D012878 Skin Neoplasms Doxorubicin 5.8215692506
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 5.828532709
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.5015625365 17203757 16767912
MESH:D013274 Stomach Neoplasms Zidovudine 2.4717696246
MESH:D013276 Stomach Ulcer Acetylcysteine 3.9417918041
MESH:D019966 Substance-Related Disorders bisphenol A 3.9216684133 16045194
MESH:D013733 Testicular Diseases phenethyl isothiocyanate 4.8815864552
MESH:D013921 Thrombocytopenia Lipopolysaccharides 4.1015821434
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 7.091399818 7505956 6587162 3712494 6582329
MESH:D013964 Thyroid Neoplasms Doxorubicin 7.0916010429 17909728
MESH:D013978 Tibial Fractures Estradiol 4.6319048282
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 5.108074119
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 5.1017653716
MESH:D014591 Uterine Diseases bisphenol A 4.9514652134
MESH:D014605 Uveitis Cyclosporine 3.931336536
MESH:D014625 Vaginal Neoplasms Zidovudine 4.6912579204
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.1617678736 17638931 16364871 17334414
MESH:D014985 Xerophthalmia Cyclosporine 4.3917120751
Pathway ID Pathway Name
KEGG:04722 Neurotrophin signaling pathway
KEGG:04621 NOD-like receptor signaling pathway
KEGG:05131 Shigellosis
REACT:6900 Signaling in Immune system
REACT:11061 Signalling by NGF
KEGG:05152 Tuberculosis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA34395
    • No data
    Releated disease ID Related disease Name
    PA444745Leprosy
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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