AutismKB 2.0

Annotation Detail for TNFRSF10B


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TNFRSF10B ( CD262,DR5,KILLER,KILLER/DR5,TRAIL-R2,TRAILR2,TRICK2,TRICK2A,TRICK2B,TRICKB,ZTNFR9 )
Gene Full Name: tumor necrosis factor receptor superfamily, member 10b
Band: 8p21.3
Quick LinksEntrez ID:8795; OMIM: 603612; Uniprot ID:TR10B_HUMAN; ENSEMBL ID: ENSG00000120889; HGNC ID: 11905
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04650Natural killer cell mediated cytotoxicity
hsa04115p53 signaling pathway
hsa04060Cytokine-cytokine receptor interaction
hsa04210Apoptosis
Pathway IDPathway Name
Apoptosis
Pathway IDPathway Name
200101Direct p53 effectors
200056TRAIL signaling pathway
Pathway IDPathway Name
P00006Apoptosis signaling pathway
P00059p53 pathway
Pathway IDPathway Name
500257TRAIL signaling
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1860Brain tumor
1904Diabetes mellitus
1942Emphysema
1943Adenocarcinoma
1944Breast cancer
2007Liver tumor
2051Leukemia
2224Rhabdomyosarcoma
No data
No data
Desease Name
Squamous cell carcinoma, head and neck
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C036837 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone results in increased expression of TNFRSF10B proteinincreases expression 17645780
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of TNFRSF10Bincreases expression 15942663
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of TNFRSF10B mRNAincreases expression 16788091
C480030 4-(3-(1-adamantyl)-4-hydroxyphenyl)-3-chlorocinnamic acid 4-(3-(1-adamantyl)-4-hydroxyphenyl)-3-chlorocinnamic acid results in increased expression of TNFRSF10B proteinincreases expression 15930313
C119130 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide results in increased expression of TNFRSF10B mRNAincreases expression 12203115
C120508 A 192621 A 192621 results in increased expression of TNFRSF10B mRNAincreases expression 19040731
C103303 alitretinoin alitretinoin results in increased expression of TNFRSF10B mRNAincreases expression 16449964
D001151 Arsenic [Arsenic co-treated with Fluorides] results in increased expression of TNFRSF10B mRNAaffects cotreatment|increases expression 19962721
C006632 arsenic trioxide bortezomib promotes the reaction [arsenic trioxide results in increased activity of TNFRSF10B]increases activity|increases reaction 20471514
C015001 arsenite arsenite results in increased expression of TNFRSF10B mRNAincreases expression 18585952
C015001 arsenite XPA protein affects the reaction [arsenite results in increased expression of TNFRSF10B mRNA]affects reaction|increases expression 18585952
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of TNFRSF10B mRNAincreases expression 18687144
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of TNFRSF10B mRNAincreases expression 20064835
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TNFRSF10B mRNAdecreases expression 19150397
C072553 benzyloxycarbonylleucyl-leucyl-leucine aldehyde benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TNFRSF10B proteinincreases expression 16287099
C400082 bortezomib bortezomib promotes the reaction [arsenic trioxide results in increased activity of TNFRSF10B]increases activity|increases reaction 20471514
C006862 butylphen butylphen results in increased expression of TNFRSF10B proteinincreases expression 15816839
D002699 Chlorambucil Chlorambucil affects the expression of TNFRSF10B proteinaffects expression 14614459
D002699 Chlorambucil Chlorambucil results in increased expression of TNFRSF10B mRNAincreases expression 18092340
D002699 Chlorambucil Chlorambucil results in increased expression of TNFRSF10B proteinincreases expression 18092340
D003042 Cocaine Cocaine affects the expression of TNFRSF10B mRNAaffects expression 15681117
D003474 Curcumin Curcumin results in decreased expression of TNFRSF10B mRNAdecreases expression 16101141
D003474 Curcumin Curcumin results in increased expression of TNFRSF10B proteinincreases expression 18226269
16613838
D003474 Curcumin TNFRSF10B protein results in increased susceptibility to Curcuminincreases response to substance 16613838
D003474 Curcumin TNFSF10 protein promotes the reaction [Curcumin results in increased expression of TNFRSF10B protein]increases expression|increases reaction 18226269
D003474 Curcumin Curcumin results in increased expression of TNFRSF10Bincreases expression 18462866
D016572 Cyclosporine Cyclosporine results in increased expression of TNFRSF10B mRNAincreases expression 20106945
D004052 Diethylnitrosamine TNFRSF10B protein results in decreased susceptibility to Diethylnitrosaminedecreases response to substance 18079962
D004128 Dimethylnitrosamine Dimethylnitrosamine results in increased expression of TNFRSF10B proteinincreases expression 17849272
D004317 Doxorubicin Doxorubicin results in increased expression of TNFRSF10B mRNAincreases expression 16705698
17922852
D004317 Doxorubicin Doxorubicin results in increased expression of TNFRSF10B proteinincreases expression 17922852
15897917
D004317 Doxorubicin TNFRSF10B protein affects the susceptibility to Doxorubicinaffects response to substance 16098063
17922852
D004317 Doxorubicin Doxorubicin results in increased expression of TNFRSF10B mRNAincreases expression 16243910
D005047 Etoposide Etoposide promotes the reaction [TP53 protein binds to TNFRSF10B promoter]affects binding|increases reaction 15964798
D005047 Etoposide Etoposide results in increased expression of TNFRSF10B mRNAincreases expression 15964798
C024352 fludarabine fludarabine affects the expression of TNFRSF10B proteinaffects expression 14614459
C024352 fludarabine fludarabine results in increased expression of TNFRSF10B mRNAincreases expression 18092340
C024352 fludarabine fludarabine results in increased expression of TNFRSF10B proteinincreases expression 18092340
D005459 Fluorides [Arsenic co-treated with Fluorides] results in increased expression of TNFRSF10B mRNAaffects cotreatment|increases expression 19962721
D005472 Fluorouracil Fluorouracil results in increased expression of TNFRSF10B mRNAincreases expression 17982676
D005472 Fluorouracil Fluorouracil results in increased expression of TNFRSF10B proteinincreases expression 15585621
D005472 Fluorouracil TP53 protein promotes the reaction [Fluorouracil results in increased expression of TNFRSF10B mRNA]increases expression|increases reaction 17982676
D005472 Fluorouracil TNFRSF10B protein results in increased susceptibility to Fluorouracilincreases response to substance 15374982
D005492 Folic Acid Folic Acid affects the expression of TNFRSF10B mRNAaffects expression 16361273
D019833 Genistein Genistein results in decreased expression of TNFRSF10B mRNAdecreases expression 16705744
C412815 GW 4064 GW 4064 results in decreased expression of TNFRSF10B mRNAdecreases expression 14623915
D017313 Fenretinide Fenretinide promotes the reaction [DDIT3 protein results in increased expression of TNFRSF10B mRNA]increases expression|increases reaction 17273769
D017313 Fenretinide Fenretinide results in increased expression of TNFRSF10B mRNAincreases expression 17273769
D017313 Fenretinide Fenretinide results in increased expression of TNFRSF10B proteinincreases expression 15735044
17273769
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of TNFRSF10Bincreases expression 18687144
C031927 hydroquinone hydroquinone results in decreased expression of TNFRSF10B mRNAdecreases expression 15452088
D007530 Isoflurane Isoflurane results in decreased expression of TNFRSF10B mRNAdecreases expression 16978161
D008727 Methotrexate Methotrexate results in increased expression of TNFRSF10B proteinincreases expression 17637740
C066851 mithramycin A mithramycin A inhibits the reaction [Quercetin results in increased expression of TNFRSF10B mRNA]decreases reaction|increases expression 18980244
D009151 Mustard Gas Mustard Gas results in increased expression of TNFRSF10B mRNAincreases expression 18955075
C058815 N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide results in increased expression of TNFRSF10B proteinincreases expression 15520213
D015058 1-Naphthylisothiocyanate 1-Naphthylisothiocyanate results in increased expression of TNFRSF10B mRNAincreases expression 14623915
D009637 Nordihydroguaiaretic Acid Nordihydroguaiaretic Acid results in increased expression of TNFRSF10B mRNAincreases expression 17645780
D009637 Nordihydroguaiaretic Acid Nordihydroguaiaretic Acid results in increased expression of TNFRSF10B proteinincreases expression 17645780
C482205 nutlin 3 nutlin 3 results in increased expression of TNFRSF10B mRNAincreases expression 16439677
18092340
C482205 nutlin 3 nutlin 3 results in increased expression of TNFRSF10B proteinincreases expression 18092340
D009761 Nystatin Nystatin inhibits the reaction [Quercetin affects the localization of TNFRSF10B protein]affects localization|decreases reaction 17876056
D010424 Pentobarbital Pentobarbital results in decreased expression of TNFRSF10B mRNAdecreases expression 16978161
D011794 Quercetin mithramycin A inhibits the reaction [Quercetin results in increased expression of TNFRSF10B mRNA]decreases reaction|increases expression 18980244
D011794 Quercetin Nystatin inhibits the reaction [Quercetin affects the localization of TNFRSF10B protein]affects localization|decreases reaction 17876056
D011794 Quercetin Quercetin affects the localization of TNFRSF10B proteinaffects localization 17876056
D011794 Quercetin Quercetin promotes the reaction [TNFSF10 protein affects the localization of TNFRSF10B protein]affects localization|increases reaction 17876056
D011794 Quercetin Quercetin results in increased expression of TNFRSF10B mRNAincreases expression 18980244
D011794 Quercetin Quercetin results in increased expression of TNFRSF10B proteinincreases expression 18980244
D011794 Quercetin SP1 protein promotes the reaction [Quercetin results in increased expression of TNFRSF10B mRNA]increases expression|increases reaction 18980244
C059514 resveratrol resveratrol results in increased expression of TNFRSF10B mRNAincreases expression 12569576
C059514 resveratrol resveratrol results in increased expression of TNFRSF10B proteinincreases expression 17636462
D012643 Selenium Selenium results in increased expression of TNFRSF10B proteinincreases expression 12432279
C017947 sodium arsenite BLVRA protein inhibits the reaction [sodium arsenite results in increased expression of TNFRSF10B mRNA]decreases reaction|increases expression 15741166
C017947 sodium arsenite sodium arsenite results in increased expression of TNFRSF10B mRNAincreases expression 15741166
C025462 sulindac sulfide sulindac sulfide inhibits the reaction [PTGS2 protein results in decreased expression of TNFRSF10B mRNA]decreases expression|decreases reaction 12208739
C025462 sulindac sulfide sulindac sulfide results in increased expression of TNFRSF10B mRNAincreases expression 12203115
11559570
15180942
C025462 sulindac sulfide sulindac sulfide results in increased expression of TNFRSF10B proteinincreases expression 15180942
C025463 sulindac sulfone sulindac sulfone results in increased expression of TNFRSF10B mRNAincreases expression 11559570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of TNFRSF10B mRNAincreases expression 14718643
12167310
D013792 Thalidomide Thalidomide results in decreased expression of TNFRSF10B proteindecreases expression 16531263
D014212 Tretinoin [Tretinoin co-treated with zoledronic acid] results in increased expression of TNFRSF10B mRNAaffects cotreatment|increases expression 20349282
C012589 trichostatin A trichostatin A results in increased expression of TNFRSF10B mRNAincreases expression 15964798
C012589 trichostatin A trichostatin A results in increased expression of TNFRSF10B proteinincreases expression 15964798
D014635 Valproic Acid Valproic Acid results in increased expression of TNFRSF10B mRNAincreases expression 15964798
C088658 zoledronic acid [Tretinoin co-treated with zoledronic acid] results in increased expression of TNFRSF10B mRNAaffects cotreatment|increases expression 20349282
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Methotrexate 15.7412039119
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 15.7414514962 11752688 15322242
MESH:D000014 Abnormalities, Drug-Induced Thalidomide 15.748333272
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 15.748875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.4119490988
MESH:D058186 Acute Kidney Injury Folic Acid 11.6816316344 16595132 17003819
MESH:D058186 Acute Kidney Injury resveratrol 11.6816538975
MESH:D058186 Acute Kidney Injury zoledronic acid 11.6819715164
MESH:D000210 Acute-Phase Reaction zoledronic acid 4.9120200999
MESH:D000230 Adenocarcinoma arsenic trioxide 18.0219825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 18.0220127859 20464547
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 18.0216033868
MESH:D000230 Adenocarcinoma Doxorubicin 18.0217418594
MESH:D000230 Adenocarcinoma Fenretinide 18.0210697514
MESH:D000230 Adenocarcinoma Fluorouracil 18.0217638652
MESH:D000230 Adenocarcinoma Genistein 18.0211473722
MESH:D000236 Adenoma Benzo(a)pyrene 17.246695378
MESH:D000236 Adenoma Diethylnitrosamine 17.246695378 10737359
MESH:D000236 Adenoma Dimethylnitrosamine 17.2419555203
MESH:D000236 Adenoma Folic Acid 17.2416963246
MESH:D000236 Adenoma resveratrol 17.2415688382
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 8.1517162532 19061943 16434500 19052882 18056438 17620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.1516835633
MESH:D011125 Adenomatous Polyposis Coli sulindac sulfone 4.7916150858
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.1115276417
MESH:D018246 Adrenocortical Adenoma Arsenic 11.8417306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 11.8417306315 16712894
MESH:D000419 Albuminuria Doxorubicin 4.0021441931
MESH:D019973 Alcohol-Related Disorders Curcumin 4.5017887948
MESH:D000505 Alopecia Tretinoin 3.1515955085
MESH:D000544 Alzheimer Disease Curcumin 8.1215590663
MESH:D000544 Alzheimer Disease Folic Acid 8.1217116317
MESH:D000544 Alzheimer Disease resveratrol 8.1216183991 16162502
MESH:D000544 Alzheimer Disease sulindac sulfide 8.1218759972
MESH:D000550 Amblyopia Valproic Acid 4.6517688650
MESH:D000690 Amyotrophic Lateral Sclerosis Thalidomide 3.9816510725
MESH:D000740 Anemia Fluorouracil 7.0216511603 17963324 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.0211748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.7217084956
MESH:D001008 Anxiety Disorders Pentobarbital 7.7211141031 18313124
MESH:D001008 Anxiety Disorders Valproic Acid 7.7217497229
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.5119183758
MESH:D020261 Arsenic Poisoning Arsenic 2.6818414634 16835338 12569548 16251483
MESH:D001169 Arthritis, Experimental resveratrol 10.3017115116
MESH:D001169 Arthritis, Experimental Thalidomide 10.309598899
MESH:D001169 Arthritis, Experimental Tretinoin 10.3016412693
MESH:D001172 Arthritis, Rheumatoid Curcumin 6.5116807698
MESH:D001172 Arthritis, Rheumatoid Methotrexate 6.5117286800
MESH:D001172 Arthritis, Rheumatoid Tretinoin 6.5116292516
MESH:D001249 Asthma Mustard Gas 4.2710378619
MESH:D001249 Asthma Tretinoin 4.2716456186
MESH:D001260 Ataxia Telangiectasia Quercetin 4.4015336622
MESH:D050197 Atherosclerosis Arsenic 8.9812928151 19371607
MESH:D050197 Atherosclerosis Curcumin 8.9818704882
MESH:D050197 Atherosclerosis resveratrol 8.9816873680 17967414
MESH:D001321 Autistic Disorder Folic Acid 2.3821388746
MESH:D001321 Autistic Disorder Valproic Acid 2.3818177632 20603192 18558336 17688650 18775368 17157402 16609825 18316065 18940202 17507914 19232924 18985861 19460635 15238991 18396377
MESH:D001327 Autoimmune Diseases Curcumin 9.0019761891
MESH:D001327 Autoimmune Diseases Quercetin 9.0019761891
MESH:D001471 Barrett Esophagus Tretinoin 3.8516935849
MESH:D001714 Bipolar Disorder Valproic Acid 2.7620046352 17594078
MESH:D001768 Blister Mustard Gas 4.5819167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 12.3616206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 12.3612125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 12.3616197459 16206674
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.2115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 6.7315746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 6.738888407
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 10.2114601052
MESH:D019046 Bone Marrow Neoplasms Etoposide 10.2114601052
MESH:D001859 Bone Neoplasms zoledronic acid 4.4316778634 15867366 17312309 16121404 19442620 11697798
MESH:D001862 Bone Resorption zoledronic acid 4.1918404659 15845617 8053405 18496637 16769263 11869084
MESH:D002545 Brain Ischemia Curcumin 8.4216770732
MESH:D002545 Brain Ischemia resveratrol 8.4217600658
MESH:D001932 Brain Neoplasms Curcumin 11.9017596214
MESH:D001932 Brain Neoplasms Doxorubicin 11.9017150277
MESH:D001932 Brain Neoplasms Fenretinide 11.9016187019
MESH:D001943 Breast Neoplasms alitretinoin 16.0816344269
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 16.0817474063 20146248
MESH:D001943 Breast Neoplasms Curcumin 16.0819250217 18462866 18593918 16243823
MESH:D001943 Breast Neoplasms Diethylnitrosamine 16.0817474063
MESH:D001943 Breast Neoplasms Doxorubicin 16.0819526202 16595493 11325840 15668708 17369602 15993339 17983394 15692762 16115903 18695136 16096432 16826403 18628466 15136595 15634643 16322301 16264153 17426702 16935488 18234424 15939500 15567936 18382427 15994142
MESH:D001943 Breast Neoplasms Etoposide 16.0816322251
MESH:D001943 Breast Neoplasms Fenretinide 16.0816601279
MESH:D001943 Breast Neoplasms Fluorouracil 16.0816110121 16595493 19217205 18357371 15136595 16557594 18608205
MESH:D001943 Breast Neoplasms Folic Acid 16.0816777985
MESH:D001943 Breast Neoplasms Genistein 16.0817200150 16873071 16541309
MESH:D001943 Breast Neoplasms Methotrexate 16.0816978400
MESH:D001943 Breast Neoplasms Nordihydroguaiaretic Acid 16.0818418215
MESH:D001943 Breast Neoplasms Quercetin 16.0818628248
MESH:D001943 Breast Neoplasms resveratrol 16.0817534123 16393696 17651959
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 16.0820435547
MESH:D001943 Breast Neoplasms Tretinoin 16.0816166294 16443354 16873071
MESH:D001943 Breast Neoplasms zoledronic acid 16.0818695136 16096432
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.5815286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.3917687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.0116813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.8011589617
MESH:D002105 Cadmium Poisoning Quercetin 4.9616962696
MESH:D002276 Carcinoid Tumor Doxorubicin 10.4016051944
MESH:D002276 Carcinoid Tumor Fluorouracil 10.4016051944
MESH:D002277 Carcinoma Curcumin 16.1818593918
MESH:D002277 Carcinoma Dimethylnitrosamine 16.1819555203
MESH:D002277 Carcinoma Fluorouracil 16.1817121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 16.1816835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.2415504454 17687452
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.5716168501
MESH:D006528 Carcinoma, Hepatocellular Arsenic 26.0917306315 16507464
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 26.0916217749 15073043 14691202 11135700 15553829
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 26.0920514400 20524982 18691550 18665156 20214788 11831363 20432363 19822196 17055752 16540662 16328049 19335982 18788625 17978847 16878318 3581430 16681979 3084413 16502159 20512989 16935385 16830150 20727157 19539802 18056438 19418558 19919837 18978308 18506893 20084675 19208518 18494052 10672840 21159647 16569478 16807293 19171122 19519916 17138121 18971187 17761372 17173139 19394651 20101231 16288022 16779866 17162532 19701751 19107877 19383236 17428255 18393292 16698587 20935162 20007298 18210153 18785209 10737359 19052882
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 26.0918059187 16023760 17876044 16234567
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 26.0916270382 17159502
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 26.0918930000 17045692 16799960 16332177 17088986 17971768
MESH:D006528 Carcinoma, Hepatocellular Genistein 26.0916924424
MESH:D006528 Carcinoma, Hepatocellular Quercetin 26.0912508355 19519916
MESH:D006528 Carcinoma, Hepatocellular resveratrol 26.0916227395 19321006
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 26.0915276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Thalidomide 26.0916313753
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 26.091917145
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.0216675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung bortezomib 14.3416052434
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 14.3418414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung sulindac sulfide 14.3412391285
MESH:D002289 Carcinoma, Non-Small-Cell Lung sulindac sulfone 14.3418758305
MESH:D002289 Carcinoma, Non-Small-Cell Lung zoledronic acid 14.3419233551
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.3917234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.2919014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 9.1816201981 1485588
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 9.1818695887
MESH:D002292 Carcinoma, Renal Cell zoledronic acid 9.1818507039
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.6112490120
MESH:D002294 Carcinoma, Squamous Cell Arsenic 30.0115504454 17687452 18922899
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 30.0120419170
MESH:D002294 Carcinoma, Squamous Cell Curcumin 30.0118462866
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 30.0116033868
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 30.016189445
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 30.0116274795
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 30.0117066447 18986760 16757204 16280240
MESH:D002294 Carcinoma, Squamous Cell resveratrol 30.0116227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 30.0118572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 30.0116096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Arsenic 3.5818640142
MESH:D006332 Cardiomegaly Quercetin 5.6519794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.6518670907 18850075 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 3.1417928571 17007740 16278810 16364871 16731534 16651473 15792986 16455267 17382496 16612575 17924179 16242529 17974986 16109756 16952015 15505089 16269455 15476868 15811867 17519947 17131338 17329180 18627295 17351982 17308081
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.7217334414 16243910
MESH:D002318 Cardiovascular Diseases Arsenic 18.3815738583 19152805 17938729
MESH:D002318 Cardiovascular Diseases Folic Acid 18.3816755160
MESH:D002318 Cardiovascular Diseases Genistein 18.3816332659
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 18.3816936243
MESH:D002318 Cardiovascular Diseases resveratrol 18.3815458977
MESH:D002340 Carotid Artery Diseases Arsenic 3.8216973168 18022660
MESH:D002386 Cataract Tretinoin 2.7317460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 12.6420889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 12.6412371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 12.6421159647 7505956 17174075 2727394
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 12.6419524636 20056578
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 11.0616154183
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 11.0616129372
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.4720734317
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 13.3819052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 13.3816835633
MESH:D018281 Cholangiocarcinoma Thalidomide 13.3818291259
MESH:D002761 Cholangitis 1-Naphthylisothiocyanate 5.6112912871
MESH:D002779 Cholestasis 1-Naphthylisothiocyanate 6.867624871 19486331 16629650 15913567 15500046 18590720 12927374 18164287
MESH:D002779 Cholestasis Cyclosporine 6.8619486331
MESH:D002780 Cholestasis, Intrahepatic 1-Naphthylisothiocyanate 5.2710220858 19407337
MESH:D002822 Choriocarcinoma Tretinoin 4.5716461808
MESH:D002971 Cleft Lip Folic Acid 3.6521254359
MESH:D002972 Cleft Palate Folic Acid 8.2921254359 8946559
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 8.298697196 12621046 16354765 15340226 15668235
MESH:D002972 Cleft Palate Tretinoin 8.299407595
MESH:D019970 Cocaine-Related Disorders Cocaine 5.1419606084
MESH:D003092 Colitis Curcumin 23.9918200517 16782535 16804969
MESH:D003092 Colitis resveratrol 23.9916474422
MESH:D003092 Colitis Selenium 23.9917936198
MESH:D003092 Colitis Thalidomide 23.9916680017
MESH:D003092 Colitis Tretinoin 23.9917035595
MESH:D003103 Coloboma Curcumin 4.0318809619
MESH:D003110 Colonic Neoplasms marker/mechanism 19050079
MESH:D003110 Colonic Neoplasms arsenite 15.0515037631
MESH:D003110 Colonic Neoplasms Curcumin 15.0519359593 16340194
MESH:D003110 Colonic Neoplasms Fluorouracil 15.0517018589 17725105 17172411 16510598 17287894 15001691 16340194 18772588 17169374 17016597
MESH:D003110 Colonic Neoplasms Genistein 15.0517182828
MESH:D003110 Colonic Neoplasms Nordihydroguaiaretic Acid 15.0515936596
MESH:D003110 Colonic Neoplasms Quercetin 15.0516640504 17191121 19440933 19056647 15741050 11134977 17148506
MESH:D003110 Colonic Neoplasms resveratrol 15.0516338953
MESH:D015179 Colorectal Neoplasms arsenic trioxide 11.3320501625
MESH:D015179 Colorectal Neoplasms Doxorubicin 11.3318802399 18259882
MESH:D015179 Colorectal Neoplasms Fenretinide 11.3317273769
MESH:D015179 Colorectal Neoplasms Fluorouracil 11.3320501625 18383874 17695437 14970324 18802399 18448328 16524972 17255274 16282729 17454858 16391804 15289873 17401013 18288408 16331619 18509181 15148649 17594712 18949393 16303861 17094418 17016601
MESH:D015179 Colorectal Neoplasms Folic Acid 11.3317087956 17116713 16963246 17245555 16985020
MESH:D015179 Colorectal Neoplasms Quercetin 11.3318095365 18852136
MESH:D015179 Colorectal Neoplasms resveratrol 11.3316550006
MESH:D015179 Colorectal Neoplasms sulindac sulfone 11.3310666051 11197048 18059344 10416599
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.5714669216 17141729
MESH:D016510 Corneal Neovascularization Curcumin 10.7418497527
MESH:D016510 Corneal Neovascularization Thalidomide 10.749301478
MESH:D003327 Coronary Disease resveratrol 3.3616507316
MESH:D023903 Coronary Restenosis arsenic trioxide 3.6412609071
MESH:D003389 Cranial Nerve Diseases Thalidomide 5.729200351
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 8.3110525206
MESH:D019465 Craniofacial Abnormalities Methotrexate 8.319562676 12039119
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 8.3110048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Thalidomide 8.319200351
MESH:D019465 Craniofacial Abnormalities Tretinoin 8.3116925845 10589399 9664655 8800419 9125849 17551590 14991402 9142499 9224671 9211117
MESH:D019465 Craniofacial Abnormalities Valproic Acid 8.3116575769 8888407 17688650
MESH:D003424 Crohn Disease Thalidomide 3.8616078585
MESH:D003550 Cystic Fibrosis Methotrexate 3.7419747007
MESH:D007644 Darier Disease Fluorouracil 4.2216733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.5615213294
MESH:D003882 Dermatomyositis Methotrexate 4.5820191521
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 6.9919496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 6.9916873680
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 11.7018403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 11.7020387270
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 11.7016886840
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 11.7016647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 11.7017107852
MESH:D003928 Diabetic Nephropathies Curcumin 7.6218204486
MESH:D003928 Diabetic Nephropathies resveratrol 7.6216286809
MESH:D056486 Drug-Induced Liver Injury 1-Naphthylisothiocyanate 15.4218289764 17522070 20133375 7624871
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 15.4219107877
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 15.428172417
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 15.4217416283
MESH:D056486 Drug-Induced Liver Injury Selenium 15.4215131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 15.4220420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 15.4219641884 1733752
MESH:D004362 Drug Toxicity Doxorubicin 6.6618602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 6.6611462148
MESH:D004381 Duodenal Ulcer Curcumin 3.5117351913
MESH:D004421 Dystonia Valproic Acid 3.521851702
MESH:D004487 Edema 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone 12.417812673
MESH:D004487 Edema Mustard Gas 12.4111428647 11402378 11428631 9260866
MESH:D004487 Edema resveratrol 12.418985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 12.4111000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.0016714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 10.0018230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 3.4917872969
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 5.0519294695
MESH:D004714 Endometrial Hyperplasia Genistein 4.0116402032
MESH:D016889 Endometrial Neoplasms Doxorubicin 14.6117359293
MESH:D016889 Endometrial Neoplasms Folic Acid 14.6117301261
MESH:D016889 Endometrial Neoplasms Genistein 14.6111473722
MESH:D016889 Endometrial Neoplasms Tretinoin 14.6116569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.529294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.5718037988
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.2917923197
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 3.593659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 3.3416628512 3922381
MESH:D004827 Epilepsy Valproic Acid 2.6220417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.107562514 6254150 6426943
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 3.747750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.493659116
MESH:D004890 Erythema Mustard Gas 4.589357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.5316302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 11.8220426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 11.8212903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 11.8216530937
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 11.8217016578
MESH:D004938 Esophageal Neoplasms Fluorouracil 11.8216481741 17638652 15173087 16785472 16337965
MESH:D017889 Exfoliation Syndrome Folic Acid 4.9216504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.3811564622
MESH:D005124 Eye Abnormalities Tretinoin 7.389664655 16938888
MESH:D005234 Fatty Liver arsenic trioxide 24.0815073043
MESH:D005234 Fatty Liver arsenite 24.0818296743
MESH:D005234 Fatty Liver Curcumin 24.0819297423
MESH:D005234 Fatty Liver Cyclosporine 24.0819224547
MESH:D005234 Fatty Liver Diethylnitrosamine 24.0820387270 21071580
MESH:D005234 Fatty Liver Valproic Acid 24.0819224547 14986274
MESH:D005264 Femoral Fractures zoledronic acid 5.2516234978
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.9011858732
MESH:D005315 Fetal Diseases Valproic Acid 4.3016575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.598888407 18558336
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.0119069698
MESH:D005355 Fibrosis arsenite 27.2818296743
MESH:D005355 Fibrosis Curcumin 27.2818705752
MESH:D005355 Fibrosis Cyclosporine 27.2812168785 12639820
MESH:D005355 Fibrosis Quercetin 27.2819474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 27.2820067830
MESH:D005355 Fibrosis Tretinoin 27.2817994277
MESH:D005534 Foot Diseases Arsenic 4.976392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.7116904648
MESH:D005756 Gastritis Folic Acid 4.5017171786
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.1318462866
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.1016452187
MESH:D005871 Giant Lymph Node Hyperplasia Thalidomide 5.7212701121
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.648708960
MESH:D005901 Glaucoma Folic Acid 4.5516504073
MESH:D005909 Glioblastoma Curcumin 27.4417596214
MESH:D005909 Glioblastoma Doxorubicin 27.4417150277
MESH:D005909 Glioblastoma Fenretinide 27.4416187019
MESH:D005909 Glioblastoma Genistein 27.4416598420
MESH:D005909 Glioblastoma Quercetin 27.4419804834
MESH:D005909 Glioblastoma Tretinoin 27.4417312396
MESH:D005909 Glioblastoma trichostatin A 27.4418801729
MESH:D005910 Glioma Fluorouracil 8.5416145905
MESH:D005910 Glioma Quercetin 8.5417643826
MESH:D005910 Glioma Thalidomide 8.5416327979
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.0110696789
MESH:D006086 Graft vs Host Disease Methotrexate 4.5916518429
MESH:D006258 Head and Neck Neoplasms Curcumin 15.1518462866 18829502
MESH:D006258 Head and Neck Neoplasms Doxorubicin 15.1515692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 15.1518337622 15102660 15162350
MESH:D006258 Head and Neck Neoplasms Tretinoin 15.1516096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.5716084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 13.2720471113
MESH:D006330 Heart Defects, Congenital Folic Acid 13.2717286298 16524890
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 13.2711294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 13.279664655 14991402
MESH:D006331 Heart Diseases Doxorubicin 3.0818006777 16144979 17875725 16707910 16244371 14766674 17888722 16879835 12587719 16495754 18674790 16244372 16330681
MESH:D006333 Heart Failure Doxorubicin 6.0017481944
MESH:D006333 Heart Failure Selenium 6.0017162251
MESH:D006394 Hemangiosarcoma Doxorubicin 3.3915692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.8515720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.8211000095
MESH:D006505 Hepatitis 1-Naphthylisothiocyanate 4.1518590720
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.3412621046 15340226 16120746
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.4817701891
MESH:D006561 Herpes Simplex Etoposide 8.2010809021
MESH:D006561 Herpes Simplex resveratrol 8.2016876885
MESH:D006679 HIV Seropositivity Folic Acid 4.9217209195
MESH:D006689 Hodgkin Disease Doxorubicin 9.5915147373 17606976 18501091
MESH:D006689 Hodgkin Disease Etoposide 9.5916135485 18180244 15147373 16200630 17606976
MESH:D006689 Hodgkin Disease sodium arsenite 9.5912676792
MESH:D006849 Hydrocephalus Valproic Acid 4.2917688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.4618606429 8697196 16959395 15340226 16354765
MESH:D006930 Hyperalgesia Tretinoin 6.6716870215
MESH:D006930 Hyperalgesia zoledronic acid 6.6716769263
MESH:D006934 Hypercalcemia bortezomib 9.7218089816
MESH:D006934 Hypercalcemia zoledronic acid 9.7218089816 19622757
MESH:D006937 Hypercholesterolemia Curcumin 7.6718704882
MESH:D006937 Hypercholesterolemia resveratrol 7.6717188708
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.0116778211
MESH:D006943 Hyperglycemia Quercetin 3.5318262572 11834736
MESH:D020138 Hyperhomocysteinemia Folic Acid 4.0116865747 16433478 16395265 16755160 16397167
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 3.9517050553
MESH:D006949 Hyperlipidemias resveratrol 3.5016873680
MESH:D006973 Hypertension Arsenic 10.269931084 11953799 16076760
MESH:D006973 Hypertension Cyclosporine 10.2610903974
MESH:D006973 Hypertension Quercetin 10.2618356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 10.2618850075 18670907
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.8017488730
MESH:D006987 Hypesthesia Arsenic 4.9716093927
MESH:D006996 Hypocalcemia zoledronic acid 5.6112669777
MESH:D007022 Hypotension Isoflurane 4.4112967683
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.0917600658
MESH:D007248 Infertility, Male sodium arsenite 2.6015346721 12646999
MESH:D007249 Inflammation Curcumin 15.7016956363 18403477 17151092
MESH:D007249 Inflammation Diethylnitrosamine 15.7018785209
MESH:D007249 Inflammation Mustard Gas 15.7011428647 8975870 16001271 17524151 11428620 9357497 9260866 11428631 11402378
MESH:D007249 Inflammation resveratrol 15.7016366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 15.7012878042 12200463
MESH:D007249 Inflammation Thalidomide 15.7016134734
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.9518596194 18200517
MESH:D007251 Influenza, Human Nordihydroguaiaretic Acid 21.9118473937
MESH:D007251 Influenza, Human Quercetin 21.9116624496
MESH:D007251 Influenza, Human resveratrol 21.9116624496
MESH:D007251 Influenza, Human Selenium 21.9116624496
MESH:D007410 Intestinal Diseases Tretinoin 3.2117994277
MESH:D007414 Intestinal Neoplasms Curcumin 3.7210783313
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.2216580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.2217551590 15992940
MESH:D007627 Keloid Quercetin 4.3917086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.8515604871
MESH:D007642 Keratosis Arsenic 4.4116930632 12749816
MESH:D017492 Keratosis, Seborrheic alitretinoin 5.0616144296
MESH:D007674 Kidney Diseases Cyclosporine 11.5510903974 8314463 18776723
MESH:D007674 Kidney Diseases Doxorubicin 11.5516775033 15369732 15699352
MESH:D007674 Kidney Diseases Quercetin 11.5516962696
MESH:D007674 Kidney Diseases sodium arsenite 11.5520008137
MESH:D007676 Kidney Failure, Chronic Doxorubicin 13.7616707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 13.7616518626
MESH:D007676 Kidney Failure, Chronic Selenium 13.7616518626
MESH:D007680 Kidney Neoplasms Cyclosporine 5.8412371664
MESH:D007680 Kidney Neoplasms Fluorouracil 5.8416985049
MESH:D007805 Language Development Disorders Methotrexate 4.579562676
MESH:D007889 Leiomyoma Curcumin 4.0418555241
MESH:D007898 Leishmaniasis, Visceral Thalidomide 3.9016514283
MESH:D007938 Leukemia 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 20.5212970779
MESH:D007938 Leukemia arsenic trioxide 20.5215070760
MESH:D007938 Leukemia Curcumin 20.5218462866
MESH:D007938 Leukemia Genistein 20.5217468513 18980019
MESH:D007938 Leukemia Quercetin 20.5217468513
MESH:D007938 Leukemia Tretinoin 20.5217143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.5716085563
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell fludarabine 4.3017296974 17658394 18587576 17802794 18172266
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 19.0112560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell bortezomib 19.0118089816
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 19.0116106398
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell zoledronic acid 19.0118089816
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.7316972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 2.9914633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 7.7619077051
MESH:D007951 Leukemia, Myeloid Tretinoin 7.7616932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 12.9917050201 19850784 20471514 16968895 16467208
MESH:D015470 Leukemia, Myeloid, Acute bortezomib 12.9920471514
MESH:D015470 Leukemia, Myeloid, Acute Thalidomide 12.9918720364
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 12.9917596541 16294345 19850784
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 12.9918206229
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 12.9916294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 14.9517339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 14.9516966277 17712046 17869043 15336539 19075265 16330433 11161223 17649720 15213294 15748426 16891316 19642359 12679006 19035177 15622746 12018890 19225113 12712474 17107899 9834237 17217047 16331271 16112521 16823087 11468182
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 14.9516087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 14.9516766008 17301526 17368321 17506722 17107899 19225113 17361223 16891316 17649720 16935935 15748426 19075265 16823087 19029980 17294898 12679006 16140955 16331271 19035177 17217047 19642359 9834237 17339181 16788101 17712046
MESH:D015458 Leukemia, T-Cell arsenic trioxide 9.9016882451
MESH:D015458 Leukemia, T-Cell Curcumin 9.9016106398
MESH:D007972 Leukoplakia, Oral Fenretinide 5.4616707609
MESH:D017880 Limb Deformities, Congenital Thalidomide 7.1410473037
MESH:D017880 Limb Deformities, Congenital Tretinoin 7.149224671
MESH:D008103 Liver Cirrhosis arsenite 13.0518296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 13.0518407596 18665156 19638242 20032147 18522880
MESH:D008103 Liver Cirrhosis Methotrexate 13.0514986274
MESH:D008103 Liver Cirrhosis Thalidomide 13.0516943688 17174718
MESH:D008106 Liver Cirrhosis, Experimental 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide 13.7015876570
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 13.7017355460 18006644 18705752
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 13.7015067225 15161499 18672772 15744066 18364076 17724770 17432682 18629640 17201889 17198567 15864749 18567088 15763062 16009107 14709902 17881167 14568256 18637143 15479170 15793283 15383259 15504291 17719030 14643895 18095165 15366600 16627068 16570917 17465448 15339415 16042886 16270385 15099470 18371158 15942678 18210741 17666798 15842777 15492853 15591649 14726149 18237412 17348192 14659978 15081153 16169303 17036385 17196135 15369754 15733078 17534399 12918455 15086199 15577212 17203207 16544323 16603200 15298665 15571005 17640959 18239293 12925901 15723089 15798949 15138612
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 13.7016439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Genistein 13.7017823541
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 13.7012741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 13.7012878042
MESH:D008106 Liver Cirrhosis, Experimental Thalidomide 13.7015465738
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 13.7016248980 18397230
MESH:D008107 Liver Diseases 1-Naphthylisothiocyanate 10.5517184895
MESH:D008107 Liver Diseases Arsenic 10.5511134558
MESH:D008107 Liver Diseases Curcumin 10.5516956363
MESH:D008107 Liver Diseases Diethylnitrosamine 10.5517034775
MESH:D008107 Liver Diseases Folic Acid 10.5516877991
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 3.9117457977
MESH:D008113 Liver Neoplasms Arsenic 28.7716368122
MESH:D008113 Liver Neoplasms arsenic trioxide 28.7714682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 28.7721137059 20195826
MESH:D008113 Liver Neoplasms Diethylnitrosamine 28.7718977376 19833225 19254457 19256749 18978307 19073162 2862719 2422723 19294768 19551842 21071580 20405173 20118626 18644402 20501860 19996281 18648771 19499222 15175105 19690152 19642983 10737359 20101389 19812893 20452335 21167192 20492335 19255062 21278145 18754104 9163691 21047994 20137499 19090486 15885732 19427195 12112319 19426721 20583210 12771043 19638242 16942905 19850985 20434301
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 28.7715890375 3113478
MESH:D008113 Liver Neoplasms Fluorouracil 28.7718383874 16603448 17045692 15113037
MESH:D008113 Liver Neoplasms Quercetin 28.7718980244
MESH:D008113 Liver Neoplasms resveratrol 28.7719321006 19812893 20405173 19073162
MESH:D008113 Liver Neoplasms sodium arsenite 28.7715276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 28.7716984957
MESH:D008114 Liver Neoplasms, Experimental therapeutic 18079962
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 18.4520377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 18.452563599 9362446 16842330 17174075 18544905 19539802 17942915 19004024 18775883 16267830 18253720 19519916 18282651 19009564 18308698 18164116 21159647 18079962 3124819 18093689 19126423 17854601
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 18.456150874 15603536 1848544
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 18.4517085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Quercetin 18.4519519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 18.4512151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.9115213294
MESH:D008171 Lung Diseases Mustard Gas 6.2018702808 18161513
MESH:D008171 Lung Diseases sodium arsenite 6.2019095001
MESH:D017563 Lung Diseases, Interstitial Methotrexate 9.5218516814
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 9.5217228818
MESH:D055370 Lung Injury Asbestos, Crocidolite 3.4717365036
MESH:D008175 Lung Neoplasms alitretinoin 25.9216413115
MESH:D008175 Lung Neoplasms Arsenic 25.9217976673 17306315 19168569
MESH:D008175 Lung Neoplasms arsenic trioxide 25.9211798837 19825857
MESH:D008175 Lung Neoplasms arsenite 25.9216809336
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 25.9220064080 20464547 20869020 18520028 20135361 18816296 6695378 18569708 17053015
MESH:D008175 Lung Neoplasms Curcumin 25.9218462866 16243823 19359593
MESH:D008175 Lung Neoplasms Diethylnitrosamine 25.9220512841 20970405 6695378 21163286
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 25.9216061637 11884234 19555203
MESH:D008175 Lung Neoplasms Doxorubicin 25.926189445 17418594
MESH:D008175 Lung Neoplasms Fluorouracil 25.9215246190
MESH:D008175 Lung Neoplasms Mustard Gas 25.923148597 8781369
MESH:D008175 Lung Neoplasms Quercetin 25.9216280456
MESH:D008175 Lung Neoplasms sodium arsenite 25.9215276417 16712894 17077188 19931552 17306315
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 25.9211884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.2215086387
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 3.1517718048
MESH:D008223 Lymphoma bortezomib 23.7716098063
MESH:D008223 Lymphoma Chlorambucil 23.7710745627
MESH:D008223 Lymphoma Curcumin 23.7718462866
MESH:D008223 Lymphoma Doxorubicin 23.7716098063
MESH:D008223 Lymphoma Etoposide 23.7712556972 12854902
MESH:D008223 Lymphoma Methotrexate 23.7717352296
MESH:D016393 Lymphoma, B-Cell bortezomib 8.9816675587
MESH:D016393 Lymphoma, B-Cell resveratrol 8.9817088997
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 7.3117654614
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 7.3114749477
MESH:D016399 Lymphoma, T-Cell Curcumin 9.7016173963
MESH:D016399 Lymphoma, T-Cell Doxorubicin 9.7015621674
MESH:D015674 Mammary Neoplasms, Animal resveratrol 3.6815688416
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 18.5515458769
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 18.5510697514
MESH:D008325 Mammary Neoplasms, Experimental Genistein 18.5512929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 18.558985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental Selenium 18.5515318939
MESH:D008325 Mammary Neoplasms, Experimental zoledronic acid 18.5517312309
MESH:D019767 Maxillofacial Abnormalities Folic Acid 5.1216832597
MESH:D008527 Medulloblastoma bortezomib 6.0319213072
MESH:D008527 Medulloblastoma Tretinoin 6.0317453147
MESH:D008545 Melanoma Curcumin 16.0117885582 18462866
MESH:D008545 Melanoma Doxorubicin 16.0116827129
MESH:D008545 Melanoma Fenretinide 16.0116270382
MESH:D008545 Melanoma resveratrol 16.0117992120
MESH:D008545 Melanoma sodium arsenite 16.0116487513 19082730
MESH:D008545 Melanoma Thalidomide 16.0112829675 16098027 17089043
MESH:D008545 Melanoma Tretinoin 16.0116752155
MESH:D008545 Melanoma trichostatin A 16.0116505122
MESH:D008569 Memory Disorders Curcumin 3.6117263510
MESH:D008591 Meningomyelocele Tretinoin 3.8616940565
MESH:D008654 Mesothelioma Asbestos, Crocidolite 12.4016966607 16166281 18303189
MESH:D008654 Mesothelioma Doxorubicin 12.4017638057
MESH:D008654 Mesothelioma Selenium 12.4015107826
MESH:D008654 Mesothelioma zoledronic acid 12.4016675582
MESH:D008659 Metabolic Diseases resveratrol 3.8617112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.2016801185
MESH:D008881 Migraine Disorders Valproic Acid 2.7718803445 18765137
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.9815792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 11.8716381670
MESH:D009062 Mouth Neoplasms Fenretinide 11.8716274795
MESH:D009062 Mouth Neoplasms Fluorouracil 11.8716757204 18986760
MESH:D052016 Mucositis Doxorubicin 10.6117415656
MESH:D052016 Mucositis Methotrexate 10.6117488658
MESH:D009101 Multiple Myeloma arsenic trioxide 27.5814977855 19417148 15949261 11468182 19549372
MESH:D009101 Multiple Myeloma bortezomib 27.5819372569 19112201 19112817
MESH:D009101 Multiple Myeloma Curcumin 27.5819372569
MESH:D009101 Multiple Myeloma resveratrol 27.5817935668 16490592 17049120 17164350 14749477 16267019
MESH:D009101 Multiple Myeloma Thalidomide 27.5815939924 15867202 17168659 15920492 19112201 15744524 16445831 19112817 15741222 19372569
MESH:D009101 Multiple Myeloma trichostatin A 27.5818172295
MESH:D009101 Multiple Myeloma zoledronic acid 27.5816996129 18089719 19621390
MESH:D009134 Muscular Atrophy, Spinal Curcumin 10.5017962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 10.5017962980
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.518888407
MESH:D009181 Mycoses Nystatin 6.1916374455
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.0918349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 14.7016105982 16882451
MESH:D009190 Myelodysplastic Syndromes Thalidomide 14.7018720364
MESH:D009190 Myelodysplastic Syndromes Tretinoin 14.7017596541
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 14.7017596541
MESH:D009203 Myocardial Infarction Cocaine 15.0018072171
MESH:D009203 Myocardial Infarction Doxorubicin 15.0015857846 19429709
MESH:D009203 Myocardial Infarction Genistein 15.0017141266
MESH:D009203 Myocardial Infarction Quercetin 15.0019595682
MESH:D009203 Myocardial Infarction resveratrol 15.0016317513 16525036 16456233 17015251 17188708 17125593
MESH:D017202 Myocardial Ischemia Arsenic 12.6315371236
MESH:D017202 Myocardial Ischemia resveratrol 12.6317125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 12.6312213967
MESH:D015428 Myocardial Reperfusion Injury Genistein 7.2117141266
MESH:D015428 Myocardial Reperfusion Injury Quercetin 7.2119207477
MESH:D009205 Myocarditis resveratrol 4.1817322642
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 8.5116624393
MESH:D009361 Neoplasm Invasiveness Curcumin 8.5118495463
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.129029167 3581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 8.1218259882
MESH:D009362 Neoplasm Metastasis zoledronic acid 8.1219139120 17312309 15867366
MESH:D009364 Neoplasm Recurrence, Local marker/mechanism 19050079
MESH:D009369 Neoplasms alitretinoin 19.1916946489
MESH:D009369 Neoplasms Benzo(a)pyrene 19.1911141357
MESH:D009369 Neoplasms Fenretinide 19.1917353921 15958647
MESH:D009369 Neoplasms Fluorouracil 19.1916928823 18239605 18600527
MESH:D009369 Neoplasms Quercetin 19.1915185748
MESH:D009369 Neoplasms sodium arsenite 19.1911559025
MESH:D009369 Neoplasms Tretinoin 19.1916946489 16594593
MESH:D009374 Neoplasms, Experimental resveratrol 7.388985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 7.3820056578
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 3.9512497104
MESH:D009389 Neovascularization, Pathologic arsenite 3.8415738583
MESH:D009401 Nephrosis Doxorubicin 4.2116636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.8517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 7.6718481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 7.6715640375 16889571
MESH:D009421 Nervous System Malformations Genistein 19.0316427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 19.0314600291
MESH:D009421 Nervous System Malformations Thalidomide 19.0316859833
MESH:D009421 Nervous System Malformations Tretinoin 19.039125849
MESH:D009423 Nervous System Neoplasms Curcumin 5.0418462866
MESH:D009436 Neural Tube Defects Arsenic 23.3016620997
MESH:D009436 Neural Tube Defects arsenic trioxide 23.3010525206
MESH:D009436 Neural Tube Defects Folic Acid 23.3017438019
MESH:D009436 Neural Tube Defects sodium arsenite 23.3012854658
MESH:D009436 Neural Tube Defects Tretinoin 23.309142499
MESH:D009436 Neural Tube Defects Valproic Acid 23.3016359493 8888407
MESH:D009447 Neuroblastoma Doxorubicin 2.9415555623
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 6.9620387270
MESH:D019636 Neurodegenerative Diseases resveratrol 6.9617652729
MESH:D020078 Neurogenic Inflammation Arsenic 14.7517056641
MESH:D020078 Neurogenic Inflammation Quercetin 14.7517929310
MESH:D020078 Neurogenic Inflammation resveratrol 14.7517929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.5320387270
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 5.1016303764
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.0316436463
MESH:D009503 Neutropenia Folic Acid 7.8416322990
MESH:D009503 Neutropenia Mustard Gas 7.8416761898 7688884
MESH:D009765 Obesity Curcumin 2.5819297423
MESH:D010014 Osteolysis zoledronic acid 4.8015867366
MESH:D010024 Osteoporosis Curcumin 9.8718719352
MESH:D010024 Osteoporosis Genistein 9.8719401787
MESH:D010024 Osteoporosis zoledronic acid 9.8717882678
MESH:D015663 Osteoporosis, Postmenopausal Genistein 13.8316169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 13.8319495926
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 13.8317513867
MESH:D012516 Osteosarcoma Doxorubicin 3.6515930896
MESH:D010051 Ovarian Neoplasms 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 35.2016211241
MESH:D010051 Ovarian Neoplasms Arsenic 35.2017306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 35.2016624393 19769630 12452020
MESH:D010051 Ovarian Neoplasms Curcumin 35.2018462866 19020741
MESH:D010051 Ovarian Neoplasms Fenretinide 35.2016133793
MESH:D010051 Ovarian Neoplasms Genistein 35.2019005980
MESH:D010051 Ovarian Neoplasms Quercetin 35.2019005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 35.2015276417 17306315
MESH:D010051 Ovarian Neoplasms Thalidomide 35.2016288038
MESH:D010051 Ovarian Neoplasms Tretinoin 35.2016936753
MESH:D010051 Ovarian Neoplasms trichostatin A 35.2019331143
MESH:D010146 Pain Tretinoin 5.6216870215
MESH:D010146 Pain zoledronic acid 5.6216475674
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 29.1715580305
MESH:D010190 Pancreatic Neoplasms Curcumin 29.1717440100 19401701 19196508
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 29.1716540662
MESH:D010190 Pancreatic Neoplasms Etoposide 29.1719003803
MESH:D010190 Pancreatic Neoplasms Fenretinide 29.1715580305
MESH:D010190 Pancreatic Neoplasms Fluorouracil 29.1716500647 16929163 15113037 19003803
MESH:D010190 Pancreatic Neoplasms Quercetin 29.1716965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 29.1715976015
MESH:D010190 Pancreatic Neoplasms trichostatin A 29.1719294695
MESH:D010212 Papilloma Hydrogen Peroxide 3.5312065085
MESH:D010235 Paraganglioma arsenic trioxide 3.6319927285
MESH:D010291 Paresis Thalidomide 5.729200351
MESH:D010382 Peliosis Hepatis 1-Naphthylisothiocyanate 11.8420133375
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 11.8412520081
MESH:D010523 Peripheral Nervous System Diseases Arsenic 3.6416093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.4116905509 6392382 15371236
MESH:D010538 Peritonitis Isoflurane 4.6717414419
MESH:D003557 Phyllodes Tumor Doxorubicin 4.5717983394
MESH:D010954 Plasmacytoma Selenium 4.3015087411
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.3310923243
MESH:D010997 Pleural Neoplasms Doxorubicin 4.5717638057
MESH:D011041 Poisoning Mustard Gas 3.2815727166
MESH:D017499 Porokeratosis alitretinoin 5.4216144296
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.0118163543
MESH:D011230 Precancerous Conditions Cyclosporine 12.5012371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 12.502563599
MESH:D011230 Precancerous Conditions Quercetin 12.5019056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Thalidomide 3.8817031469
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 12.9616679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 12.9611222880 11399792 11896295 11118676
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 12.9620603192
MESH:D055728 Primary Myelofibrosis trichostatin A 4.6917616702
MESH:D011471 Prostatic Neoplasms Arsenic 9.2316140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 9.2319131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 9.2317292933
MESH:D011471 Prostatic Neoplasms Curcumin 9.2310851300 18226269 15129424 11398177 18156803 18769126 12497104
MESH:D011471 Prostatic Neoplasms Doxorubicin 9.2315749863 18437689 16729912 15897917 16888761 16868541
MESH:D011471 Prostatic Neoplasms Etoposide 9.2317172428
MESH:D011471 Prostatic Neoplasms Fenretinide 9.2317024972
MESH:D011471 Prostatic Neoplasms Fluorouracil 9.2318626508 19082440
MESH:D011471 Prostatic Neoplasms Genistein 9.2315256057 15378649 16925846
MESH:D011471 Prostatic Neoplasms Nordihydroguaiaretic Acid 9.2318491370
MESH:D011471 Prostatic Neoplasms Quercetin 9.2317292933 14715546
MESH:D011471 Prostatic Neoplasms resveratrol 9.2317804756 17675339 17718901 17636462 16731767 15767336
MESH:D011471 Prostatic Neoplasms sodium arsenite 9.2316039940
MESH:D011471 Prostatic Neoplasms sulindac sulfone 9.2317908994 15570007
MESH:D011471 Prostatic Neoplasms Thalidomide 9.2316729912
MESH:D011471 Prostatic Neoplasms trichostatin A 9.2319789329 18798265
MESH:D011471 Prostatic Neoplasms zoledronic acid 9.2312438248 19103299
MESH:D011507 Proteinuria Arsenic 7.5221343184
MESH:D011507 Proteinuria Tretinoin 7.5216636307
MESH:D011536 Prurigo Thalidomide 5.7212755975
MESH:D011537 Pruritus Mustard Gas 3.5218058305
MESH:D019310 Pseudolymphoma Valproic Acid 3.9612752131 11422049
MESH:D011565 Psoriasis Cyclosporine 5.1216882103
MESH:D011565 Psoriasis Methotrexate 5.1217410198
MESH:D011618 Psychotic Disorders Cocaine 4.4016134406
MESH:D011625 Pterygium Tretinoin 4.2216723453
MESH:D011656 Pulmonary Emphysema Curcumin 4.0219168576
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 5.0617975199 15814490 17322281 17365031
MESH:D011658 Pulmonary Fibrosis Mustard Gas 5.0617894541 10334151 17266442 17720292 17620002
MESH:D012004 Rectal Neoplasms Fluorouracil 3.5218722050 15538739 16160472 18286688
MESH:D012021 Reflex, Abnormal Pentobarbital 5.4510930210
MESH:D051437 Renal Insufficiency Doxorubicin 14.0717922066
MESH:D051437 Renal Insufficiency Folic Acid 14.0715728788
MESH:D051437 Renal Insufficiency Methotrexate 14.0717352296
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.0016325855
MESH:D015427 Reperfusion Injury resveratrol 2.9716317513 17520802 17058453 16314181 15827377
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.5010666014 18379247
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.2918990726
MESH:D012162 Retinal Degeneration Fenretinide 3.9616303925
MESH:D012208 Rhabdomyosarcoma Tretinoin 9.1016283617 16116481
MESH:D012208 Rhabdomyosarcoma Valproic Acid 9.1019155313
MESH:D012509 Sarcoma Curcumin 7.9018462866
MESH:D012509 Sarcoma Doxorubicin 7.9017710206 15675481 15625365 17203757 16767912 18313854
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 20.1816646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 20.1814601052 16326096
MESH:D012512 Sarcoma, Ewing's Etoposide 20.1814601052
MESH:D012512 Sarcoma, Ewing's zoledronic acid 20.1816121404
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.2217846226
MESH:D012554 Schistosomiasis japonica Quercetin 4.9616862918
MESH:D012559 Schizophrenia Folic Acid 3.5116641680
MESH:D012559 Schizophrenia Valproic Acid 3.5119110320 15737665
MESH:D019873 Schnitzler Syndrome Thalidomide 5.3616096327
MESH:D012640 Seizures Cocaine 7.8610454489
MESH:D012640 Seizures Pentobarbital 7.8610087439 9754883
MESH:D012640 Seizures Valproic Acid 7.8617978042 14763951 3137016 16876388 1511512 15475178 11044598 11738929
MESH:D018805 Sepsis Curcumin 8.2318389075
MESH:D018805 Sepsis Isoflurane 8.2317414419
MESH:D012871 Skin Diseases Arsenic 7.016392382 16353154 16702368 17050553 16759981 15952646 19834688 18709164 17453740 17938729 17548696
MESH:D012871 Skin Diseases Folic Acid 7.0118709164
MESH:D012871 Skin Diseases Mustard Gas 7.0112880345 16961503 15451306
MESH:D012878 Skin Neoplasms Arsenic 31.0617029826 17050553 16251483 15504454 19538983 17976673
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 31.0619755658 10029692
MESH:D012878 Skin Neoplasms Doxorubicin 31.0615692506
MESH:D012878 Skin Neoplasms Fenretinide 31.0616467112
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 31.0612065085
MESH:D012878 Skin Neoplasms resveratrol 31.068985016 15837718
MESH:D012878 Skin Neoplasms sodium arsenite 31.0619524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 31.0616192470
MESH:D012878 Skin Neoplasms Tretinoin 31.0616467112
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.0115625365 17203757 16767912
MESH:D013118 Spinal Cord Diseases Folic Acid 4.9216361298
MESH:D016135 Spinal Dysraphism sodium arsenite 8.0412854658
MESH:D016135 Spinal Dysraphism Valproic Acid 8.0419490988
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.6812587719
OMIM:275355 SQUAMOUS CELL CARCINOMA, HEAD AND NECK marker/mechanism
MESH:D013226 Status Epilepticus Valproic Acid 3.9612833885
MESH:D013274 Stomach Neoplasms arsenic trioxide 9.1117007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 9.1120155912 2093021
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 9.1118456281
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 9.1116033868
MESH:D013274 Stomach Neoplasms Fluorouracil 9.1116951190 18396642 19084572 18567086 15786421 17522103 19015929 16424979 17498489 17172411
MESH:D013274 Stomach Neoplasms Folic Acid 9.1117171786
MESH:D013274 Stomach Neoplasms Tretinoin 9.1117261132
MESH:D013276 Stomach Ulcer Curcumin 6.1119188055 16631530
MESH:D013276 Stomach Ulcer Thalidomide 6.1115138204
MESH:D020521 Stroke Folic Acid 3.8716517955
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.9816321402
MESH:D013375 Substance Withdrawal Syndrome Pentobarbital 4.489754883 11529278
MESH:D013576 Syndactyly Methotrexate 4.499562676
MESH:D013921 Thrombocytopenia 1-Naphthylisothiocyanate 4.2520133375
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.3212697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 13.4719014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 13.477505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 13.4716010429 17909728
MESH:D013964 Thyroid Neoplasms Tretinoin 13.4717045167 16026305
MESH:D014062 Tongue Neoplasms Fluorouracil 13.6816280240
MESH:D014062 Tongue Neoplasms resveratrol 13.6816227395
MESH:D014062 Tongue Neoplasms Tretinoin 13.6816051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.3915213294
MESH:D014178 Translocation, Genetic Valproic Acid 4.6517262798
MESH:D014376 Tuberculosis Tretinoin 2.8516040207
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 3.953119515
MESH:D001749 Urinary Bladder Neoplasms Arsenic 23.9111144890 19429237 17306315 18640142 19322015 15987713 17976673
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 23.9120435036 12973940 12845720 11780464
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 23.9117053015
MESH:D001749 Urinary Bladder Neoplasms Curcumin 23.9118593936
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 23.9117653716
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 23.9116720286
MESH:D001749 Urinary Bladder Neoplasms Quercetin 23.9116720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 23.9111723127 16452187 16712894 17306315
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.088888407
MESH:D014565 Urogenital Neoplasms Curcumin 4.6918462866
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 24.3516154183
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 24.3516803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 24.3517473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 24.3511813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 24.3516129372
MESH:D014594 Uterine Neoplasms resveratrol 8.1917044934
MESH:D014594 Uterine Neoplasms sulindac sulfide 8.1918645019
MESH:D014604 Uveal Neoplasms Tretinoin 4.0216752155
MESH:D014605 Uveitis Cyclosporine 3.401336536
MESH:D014652 Vascular Diseases Arsenic 16.9317056641
MESH:D014652 Vascular Diseases sodium arsenite 16.9317056641
MESH:D014652 Vascular Diseases Thalidomide 16.9315741222
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.0112125929
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 8.4817638931 16364871 17678736 17334414
MESH:D018487 Ventricular Dysfunction, Left resveratrol 8.4817488730
MESH:D014820 Vitiligo Tretinoin 3.5116761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.6615886252
MESH:D009396 Wilms Tumor Tretinoin 3.4816287080
MESH:D014985 Xerophthalmia Cyclosporine 3.8517120751
Pathway ID Pathway Name
KEGG:04210 Apoptosis
REACT:578 Apoptosis
KEGG:04060 Cytokine-cytokine receptor interaction
KEGG:05162 Measles
KEGG:04650 Natural killer cell mediated cytotoxicity
KEGG:04115 p53 signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA36598
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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