AutismKB 2.0

Annotation Detail for FGF17


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Basic Information Top
Gene Symbol:FGF17 ( FGF-13 )
Gene Full Name: fibroblast growth factor 17
Band: 8p21.3
Quick LinksEntrez ID:8822; OMIM: 603725; Uniprot ID:FGF17_HUMAN; ENSEMBL ID: ENSG00000158815; HGNC ID: 3673
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04010MAPK signaling pathway
hsa04810Regulation of actin cytoskeleton
hsa05218Melanoma
hsa05200Pathways in cancer
Pathway IDPathway Name
Signaling by Insulin receptor
Signaling by FGFR
No data
Pathway IDPathway Name
P00021FGF signaling pathway
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1855Prostatic hypertrophy, Benign
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of FGF17 mRNAaffects expression 16483693
D004390 Chlorpyrifos Chlorpyrifos affects the expression of FGF17 mRNAaffects expression 18502319
D003976 Diazinon Diazinon results in decreased expression of FGF17 mRNAdecreases expression 19130878
D004026 Dieldrin Dieldrin results in decreased expression of FGF17 mRNAdecreases expression 19130878
D009532 Nickel Nickel results in decreased expression of FGF17 mRNAdecreases expression 19130878
D014212 Tretinoin Tretinoin results in increased expression of FGF17 proteinincreases expression 16316642
D014212 Tretinoin Tretinoin results in decreased expression of FGF17 mRNAdecreases expression 16604517
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.0218287403
MESH:D055371 Acute Lung Injury Nickel 4.9316166738
MESH:D000382 Agricultural Workers' Diseases Chlorpyrifos 10.7616611668 11874814 17119214
MESH:D000382 Agricultural Workers' Diseases Diazinon 10.7616487989
MESH:D000505 Alopecia Tretinoin 3.8715955085
MESH:D001169 Arthritis, Experimental Tretinoin 3.2516412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.3216292516
MESH:D001249 Asthma Tretinoin 2.4216456186
MESH:D001471 Barrett Esophagus Tretinoin 4.7816935849
MESH:D001778 Blood Coagulation Disorders Tretinoin 3.9316206674 16197459
MESH:D001943 Breast Neoplasms Dieldrin 2.1911859874 15770527
MESH:D001943 Breast Neoplasms Nickel 2.1915986119
MESH:D001943 Breast Neoplasms Tretinoin 2.1916443354 16873071 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 5.0516813970
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.6816168501
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 1.911917145
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 2.3616096774 16051514
MESH:D002386 Cataract Tretinoin 3.2617460283
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 5.0516129372
MESH:D002822 Choriocarcinoma Tretinoin 5.6816461808
MESH:D002972 Cleft Palate Tretinoin 2.789407595
MESH:D003092 Colitis Tretinoin 4.1217035595
MESH:D019465 Craniofacial Abnormalities Tretinoin 1.8316925845 8800419 10589399 9664655 17551590 9211117 14991402 9224671 9125849 9142499
MESH:D017449 Dermatitis, Allergic Contact Nickel 4.3617100760 17244072 19470301
MESH:D003877 Dermatitis, Contact Nickel 4.992952479
MESH:D004417 Dyspnea Diazinon 5.3216487989
MESH:D004489 Edema, Cardiac Tretinoin 4.9918230668
MESH:D016889 Endometrial Neoplasms Tretinoin 3.3016569247
MESH:D005124 Eye Abnormalities Tretinoin 3.8116938888 9664655
MESH:D005355 Fibrosis Tretinoin 3.9317994277
MESH:D005909 Glioblastoma Tretinoin 3.1917312396
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.3816096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.6816084493
MESH:D006330 Heart Defects, Congenital Tretinoin 3.0414991402 9664655
MESH:D006505 Hepatitis Diazinon 4.9516487989
MESH:D015658 HIV Infections Nickel 3.9617263646
MESH:D006930 Hyperalgesia Tretinoin 3.4616870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.9916778211
MESH:D007247 Infertility, Female Dieldrin 5.2910630421
MESH:D007248 Infertility, Male Diazinon 4.0212948887 16466525
MESH:D007249 Inflammation Nickel 3.5616166738
MESH:D007410 Intestinal Diseases Tretinoin 4.1817994277
MESH:D007569 Jaw Abnormalities Tretinoin 4.2317551590 15992940
MESH:D007938 Leukemia Tretinoin 2.9017143497
MESH:D007951 Leukemia, Myeloid Tretinoin 4.0216482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.1216294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.3412679006 17712046 17506722 19035177 16140955 16823087 19029980 16891316 17368321 17339181 16766008 16788101 17217047 17361223 16331271 17649720 19225113 19075265 15748426 19642359 16935935 17294898 17301526 17107899 9834237
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.539224671
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 1.8116248980 18397230
MESH:D008107 Liver Diseases Chlorpyrifos 3.1315991261
MESH:D008113 Liver Neoplasms Dieldrin 3.439539021 8742319
MESH:D008527 Medulloblastoma Tretinoin 2.8817453147
MESH:D008545 Melanoma Tretinoin 1.9716752155
MESH:D008591 Meningomyelocele Tretinoin 4.8416940565
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.2417596541
MESH:D009369 Neoplasms Dieldrin 5.928820588
MESH:D009369 Neoplasms Tretinoin 5.9216594593 16946489
MESH:D009421 Nervous System Malformations Tretinoin 4.169125849
MESH:D009436 Neural Tube Defects Tretinoin 3.249142499
MESH:D020258 Neurotoxicity Syndromes Chlorpyrifos 4.3715081274
MESH:D010051 Ovarian Neoplasms Tretinoin 2.4216936753
MESH:D010146 Pain Tretinoin 3.1616870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.5515976015
MESH:D010300 Parkinson Disease Dieldrin 3.6216809432 17291500 16112328 11445065 11181820
MESH:D011041 Poisoning Diazinon 4.7017603234
MESH:D011507 Proteinuria Tretinoin 3.9516636307
MESH:D011625 Pterygium Tretinoin 5.2616723453
MESH:D012135 Respiratory Sounds Chlorpyrifos 5.0511874814 16611668 17119214
MESH:D012140 Respiratory Tract Diseases Chlorpyrifos 5.4117119214 16611668
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.4516116481 16283617
MESH:D012729 Sex Chromosome Aberrations Chlorpyrifos 6.616418539
MESH:D012878 Skin Neoplasms Tretinoin 2.7316467112
MESH:D013274 Stomach Neoplasms Tretinoin 1.8017261132
MESH:D013964 Thyroid Neoplasms Tretinoin 3.2616026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 4.0916051514
MESH:D014376 Tuberculosis Tretinoin 3.4116040207
MESH:D014570 Urologic Diseases Diazinon 5.8016487989
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.9816129372
MESH:D014604 Uveal Neoplasms Tretinoin 5.1316752155
MESH:D014820 Vitiligo Tretinoin 4.4416761959
MESH:D009396 Wilms Tumor Tretinoin 4.2516287080
Pathway ID Pathway Name
KEGG:04010 MAPK signaling pathway
KEGG:05218 Melanoma
KEGG:05200 Pathways in cancer
KEGG:04810 Regulation of actin cytoskeleton
REACT:9470 Signaling by FGFR
REACT:498 Signaling by Insulin receptor
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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