AutismKB 2.0

Annotation Detail for CFLAR


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Basic Information Top
Gene Symbol:CFLAR ( CASH,CASP8AP1,CLARP,Casper,FLAME,FLAME-1,FLAME1,FLIP,I-FLICE,MRIT,c-FLIP,c-FLIPL,c-FLIPR,c-FLIPS )
Gene Full Name: CASP8 and FADD-like apoptosis regulator
Band: 2q33.1
Quick LinksEntrez ID:8837; OMIM: 603599; Uniprot ID:CFLAR_HUMAN; ENSEMBL ID: ENSG00000003402; HGNC ID: 1876
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05142Chagas disease
hsa04210Apoptosis
No data
Pathway IDPathway Name
200171Validated targets of C-MYC transcriptional repression
200133HIV-1 Nef: Negative effector of Fas and TNF-alpha
200067FAS (CD95) signaling pathway
200056TRAIL signaling pathway
Pathway IDPathway Name
P00020FAS signaling pathway
P00006Apoptosis signaling pathway
Pathway IDPathway Name
500257TRAIL signaling
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1734Muscular dystrophy
1781Rheumatoid arthritis
1934Cancer
2118Adenovirus infection
2172Chorioretinitis
2175HTLV-I infection
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C097240 15-deoxy-delta(12,14)-prostaglandin J2 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CFLAR proteindecreases expression 15498850
C047948 1'-acetoxychavicol acetate 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of CFLAR protein]decreases reaction|increases expression 15905586
C477931 1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate 1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate results in decreased expression of CFLAR proteindecreases expression 12970779
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of CFLAR mRNAaffects expression 21346803
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of CFLAR proteindecreases expression 12970779
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of CFLAR mRNAdecreases expression 16788091
C434003 3-(4-methylphenylsulfonyl)-2-propenenitrile 3-(4-methylphenylsulfonyl)-2-propenenitrile results in decreased expression of CFLAR mRNAdecreases expression 16380446
C434003 3-(4-methylphenylsulfonyl)-2-propenenitrile 3-(4-methylphenylsulfonyl)-2-propenenitrile results in decreased expression of CFLAR proteindecreases expression 16173963
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of CFLAR mRNAincreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of CFLAR mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CFLAR mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in decreased expression of CFLAR proteindecreases expression 16174796
16105982
C006632 arsenic trioxide CFLAR protein results in decreased susceptibility to arsenic trioxidedecreases response to substance 16105982
C072553 benzyloxycarbonylleucyl-leucyl-leucine aldehyde benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Quercetin results in decreased expression of CFLAR protein alternative form]decreases expression|decreases reaction 18980244
D019207 beta Carotene beta Carotene results in increased expression of CFLAR mRNAincreases expression 17034753
C006780 bisphenol A bisphenol A results in decreased expression of CFLAR mRNAdecreases expression 20678512
D002087 Butyrates Butyrates results in decreased expression of CFLAR mRNAdecreases expression 16042588
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of CFLAR mRNAincreases expression 17484886
D003042 Cocaine Cocaine affects the expression of CFLAR mRNAaffects expression 15681117
D003474 Curcumin Curcumin inhibits the reaction [TNF protein results in increased expression of CFLAR mRNA]decreases reaction|increases expression 16219905
D003474 Curcumin Curcumin results in decreased expression of CFLAR proteindecreases expression 16173963
D003513 Cycloheximide Cycloheximide results in decreased expression of CFLAR proteindecreases expression 16077199
12663669
D003609 Dactinomycin Dactinomycin results in decreased expression of CFLAR proteindecreases expression 14601052
C014347 decitabine decitabine affects the expression of CFLAR proteinaffects expression 18636160
C464444 dehydroxymethylepoxyquinomicin [dehydroxymethylepoxyquinomicin co-treated with TNF protein] results in decreased expression of CFLARaffects cotreatment|decreases expression 16211219
D002945 Cisplatin Cisplatin results in decreased expression of CFLAR proteindecreases expression 14601052
D004144 Diosgenin Diosgenin inhibits the reaction [TNF protein results in increased expression of CFLAR protein]decreases reaction|increases expression 16331273
D004144 Diosgenin Diosgenin results in decreased expression of CFLAR proteindecreases expression 16331273
D004317 Doxorubicin Doxorubicin results in decreased expression of CFLAR proteindecreases expression 14601052
15897917
D004317 Doxorubicin Doxorubicin results in decreased expression of CFLAR proteindecreases expression 15703961
D005047 Etoposide Etoposide results in increased expression of CFLAR proteinincreases expression 14601052
C049639 evodiamine evodiamine inhibits the reaction [TNF protein results in increased expression of CFLAR protein]decreases reaction|increases expression 15710601
D005472 Fluorouracil CFLAR protein affects the susceptibility to Fluorouracilaffects response to substance 15548681
16373718
16217747
D005472 Fluorouracil CFLAR protein alternative form inhibits the reaction [Fluorouracil results in increased activity of TNFSF10 protein]decreases reaction|increases activity 16373718
D005472 Fluorouracil [Fluorouracil co-treated with IFNA1 protein] results in decreased expression of CFLAR proteinaffects cotreatment|decreases expression 17045692
D005472 Fluorouracil Fluorouracil results in decreased expression of CFLAR mRNAdecreases expression 17045692
D005472 Fluorouracil Fluorouracil results in decreased expression of CFLAR proteindecreases expression 17045692
16373718
D005472 Fluorouracil Fluorouracil results in increased expression of CFLAR mRNAincreases expression 15152939
D005472 Fluorouracil IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of CFLAR mRNA]decreases expression|increases reaction 17045692
D017313 Fenretinide Fenretinide inhibits the reaction CFLAR proteindecreases reaction 16230421
D017313 Fenretinide Fenretinide inhibits the reaction [TNF protein results in increased expression of CFLAR protein]decreases reaction|increases expression 16230421
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of CFLAR proteinincreases expression 18603805
D006861 Hydrogen Peroxide Hydrogen Peroxide results in decreased expression of CFLAR proteindecreases expression 16157298
C097613 imatinib [tetraarsenic tetrasulfide co-treated with imatinib] results in decreased expression of CFLAR mRNAaffects cotreatment|decreases expression 19208803
C016517 indole-3-carbinol indole-3-carbinol inhibits the reaction [TNF protein results in increased expression of CFLAR protein]decreases reaction|increases expression 15811958
C016517 indole-3-carbinol indole-3-carbinol results in decreased expression of CFLARdecreases expression 16082211
D007213 Indomethacin Indomethacin inhibits the reaction [LTA protein results in increased expression of CFLAR protein]decreases reaction|increases expression 17873517
C051890 irinotecan CFLAR protein affects the susceptibility to irinotecanaffects response to substance 16373718
C051890 irinotecan CFLAR protein alternative form inhibits the reaction [irinotecan results in increased activity of TNFSF10 protein]decreases reaction|increases activity 16373718
C051890 irinotecan irinotecan results in decreased expression of CFLAR proteindecreases expression 16373718
C115354 lonafarnib lonafarnib inhibits the reaction [TNF protein results in increased expression of CFLAR protein]decreases reaction|increases expression 15090542
C029938 nickel sulfate nickel sulfate results in increased expression of CFLAR mRNAincreases expression 16780908
C030110 oxaliplatin CFLAR protein affects the susceptibility to oxaliplatinaffects response to substance 16373718
C030110 oxaliplatin CFLAR protein alternative form inhibits the reaction [oxaliplatin results in increased activity of TNFSF10 protein]decreases reaction|increases activity 16373718
C030110 oxaliplatin oxaliplatin results in decreased expression of CFLAR proteindecreases expression 16373718
D017239 Paclitaxel CFLAR protein results in decreased susceptibility to Paclitaxeldecreases response to substance 16080463
C526145 Phellinus linteus extract Phellinus linteus extract results in decreased expression of CFLAR protein alternative formdecreases expression 16868541
C006253 pirinixic acid pirinixic acid results in decreased expression of CFLAR mRNAdecreases expression 18445702
C023617 pregna-4,17-diene-3,16-dione pregna-4,17-diene-3,16-dione inhibits the reaction [TNF protein results in increased expression of CFLAR mRNA]decreases reaction|increases expression 15322087
D011794 Quercetin benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Quercetin results in decreased expression of CFLAR protein alternative form]decreases expression|decreases reaction 18980244
D011794 Quercetin Quercetin results in decreased expression of CFLAR protein alternative formdecreases expression 18980244
C059514 resveratrol resveratrol results in decreased expression of CFLAR proteindecreases expression 17872969
C059514 resveratrol resveratrol results in increased expression of CFLAR mRNAincreases expression 16081268
C118258 SN50 peptide SN50 peptide results in decreased expression of CFLAR proteindecreases expression 12970779
C017947 sodium arsenite sodium arsenite results in increased expression of CFLAR mRNAincreases expression 12016162
C017947 sodium arsenite sodium arsenite results in decreased expression of CFLAR mRNAdecreases expression 19822182
C025462 sulindac sulfide sulindac sulfide results in decreased expression of CFLAR proteindecreases expression 11912124
C534735 tetraarsenic tetrasulfide [tetraarsenic tetrasulfide co-treated with imatinib] results in decreased expression of CFLAR mRNAaffects cotreatment|decreases expression 19208803
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CFLAR mRNAincreases expression 12167310
D013792 Thalidomide Thalidomide results in decreased expression of CFLAR proteindecreases expression 15986355
D014212 Tretinoin [Tretinoin co-treated with TGFB1 protein] results in increased expression of CFLAR proteinaffects cotreatment|increases expression 16242776
D014415 Tunicamycin Tunicamycin results in increased expression of CFLAR mRNAincreases expression 17127020
C025643 vinclozolin vinclozolin affects the expression of CFLAR mRNAaffects expression 19015723
D014810 Vitamin E Vitamin E results in increased expression of CFLAR mRNAincreases expression 19244175
C111237 vorinostat vorinostat results in decreased expression of CFLAR proteindecreases expression 15897598
C403304 zerumbone zerumbone results in decreased expression of CFLAR mRNAdecreases expression 16007145
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 6.8215322242 11752688 14514962
MESH:D000014 Abnormalities, Drug-Induced Thalidomide 6.828333272
MESH:D000015 Abnormalities, Multiple imatinib 4.7418322153
MESH:D000022 Abortion, Spontaneous imatinib 5.6318322153
MESH:D000138 Acidosis Ammonium Chloride 2.9918287403
MESH:D058186 Acute Kidney Injury Cisplatin 7.1817670903 12690470 15814532
MESH:D058186 Acute Kidney Injury resveratrol 7.1816538975
MESH:D055371 Acute Lung Injury nickel sulfate 7.3911954676 19131640 12718980 16100012
MESH:D055371 Acute Lung Injury pirinixic acid 7.3918653653
MESH:D000230 Adenocarcinoma arsenic trioxide 14.7211798837 19825857
MESH:D000230 Adenocarcinoma Cisplatin 14.7217638652 11798837
MESH:D000230 Adenocarcinoma Doxorubicin 14.7217418594
MESH:D000230 Adenocarcinoma Fenretinide 14.7210697514
MESH:D000230 Adenocarcinoma Fluorouracil 14.7217638652
MESH:D000230 Adenocarcinoma Indomethacin 14.7216537180
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 9.223712494
MESH:D000236 Adenoma Indomethacin 9.2211497255
MESH:D000236 Adenoma resveratrol 9.2215688382
MESH:D018248 Adenoma, Liver Cell pirinixic acid 8.0016434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.0016835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.1115276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.3216712894 17306315
MESH:D000419 Albuminuria Doxorubicin 4.0021441931
MESH:D019973 Alcohol-Related Disorders Curcumin 4.5017887948
MESH:D000505 Alopecia Tretinoin 3.1515955085
MESH:D016301 Alveolar Bone Loss Indomethacin 4.7817225004
MESH:D000544 Alzheimer Disease Curcumin 8.1115590663
MESH:D000544 Alzheimer Disease Indomethacin 8.1117627676 15579461
MESH:D000544 Alzheimer Disease resveratrol 8.1116162502 16183991
MESH:D000544 Alzheimer Disease sulindac sulfide 8.1118759972
MESH:D000690 Amyotrophic Lateral Sclerosis Thalidomide 3.9816510725
MESH:D000740 Anemia Fluorouracil 7.0215504547 17963324 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.0211748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.7217084956
MESH:D000799 Angioedema Acetaminophen 3.2610982225
MESH:D001008 Anxiety Disorders vinclozolin 3.1819015723
MESH:D001014 Aortic Aneurysm Indomethacin 4.3010231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.3110388637
MESH:D018771 Arthralgia Indomethacin 4.582160914
MESH:D001169 Arthritis, Experimental resveratrol 10.3017115116
MESH:D001169 Arthritis, Experimental Thalidomide 10.309598899
MESH:D001169 Arthritis, Experimental Tretinoin 10.3016412693
MESH:D001172 Arthritis, Rheumatoid Curcumin 6.4716807698
MESH:D001172 Arthritis, Rheumatoid Indomethacin 6.4711248219
MESH:D001172 Arthritis, Rheumatoid Tretinoin 6.4716292516
MESH:D001249 Asthma Tretinoin 2.1516456186
MESH:D001260 Ataxia Telangiectasia Quercetin 4.4015336622
MESH:D050197 Atherosclerosis Curcumin 5.7118704882
MESH:D050197 Atherosclerosis resveratrol 5.7117967414 16873680
MESH:D001321 Autistic Disorder Acetaminophen 1.5018445737
MESH:D001327 Autoimmune Diseases Curcumin 9.0019761891
MESH:D001327 Autoimmune Diseases Quercetin 9.0019761891
MESH:D001471 Barrett Esophagus Tretinoin 3.8516935849
MESH:D001477 Bartter Syndrome Indomethacin 4.4210684365
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.4311289319 1440618
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 17.7216206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 17.7219483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 17.7212125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 17.7216206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.2115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.3815746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 24.5014601052
MESH:D019046 Bone Marrow Neoplasms Dactinomycin 24.5014601052
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 24.5014601052
MESH:D019046 Bone Marrow Neoplasms Etoposide 24.5014601052
MESH:D001859 Bone Neoplasms imatinib 9.2015867366
MESH:D001859 Bone Neoplasms Paclitaxel 9.2015867366
MESH:D001862 Bone Resorption bisphenol A 3.3511985600
MESH:D001929 Brain Edema Indomethacin 4.4411481608
MESH:D002545 Brain Ischemia beta Carotene 19.5916157235
MESH:D002545 Brain Ischemia Curcumin 19.5916770732
MESH:D002545 Brain Ischemia Indomethacin 19.5912524144
MESH:D002545 Brain Ischemia resveratrol 19.5917600658
MESH:D001932 Brain Neoplasms Curcumin 11.9017596214
MESH:D001932 Brain Neoplasms Doxorubicin 11.9017150277
MESH:D001932 Brain Neoplasms Fenretinide 11.9016187019
MESH:D001943 Breast Neoplasms bisphenol A 16.0817123778
MESH:D001943 Breast Neoplasms Cisplatin 16.0819526202 18382427
MESH:D001943 Breast Neoplasms Curcumin 16.0818462866 18593918 16243823 19250217
MESH:D001943 Breast Neoplasms decitabine 16.0819208741 18320071
MESH:D001943 Breast Neoplasms Doxorubicin 16.0815939500 15567936 16322301 18234424 15634643 15993339 15692762 16826403 18695136 18382427 15994142 17426702 16264153 16935488 16595493 15136595 16096432 16115903 11325840 15668708 18628466 17369602 17983394 19526202
MESH:D001943 Breast Neoplasms Etoposide 16.0816322251
MESH:D001943 Breast Neoplasms Fenretinide 16.0816601279
MESH:D001943 Breast Neoplasms Fluorouracil 16.0815136595 18357371 19217205 18608205 16557594 16110121 16595493
MESH:D001943 Breast Neoplasms imatinib 16.0817614352
MESH:D001943 Breast Neoplasms indole-3-carbinol 16.0816082211
MESH:D001943 Breast Neoplasms Indomethacin 16.0817401462
MESH:D001943 Breast Neoplasms Paclitaxel 16.0816244791 16115903 16273361 18223236 15136595 11325840 18323546 18234424
MESH:D001943 Breast Neoplasms Quercetin 16.0818628248
MESH:D001943 Breast Neoplasms resveratrol 16.0816393696 17651959 17534123
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 16.0820435547
MESH:D001943 Breast Neoplasms Tretinoin 16.0816873071 16443354 16166294
MESH:D001943 Breast Neoplasms vorinostat 16.0816144943
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.0116813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.8011589617
MESH:D002056 Burns Indomethacin 4.1410459503
MESH:D002100 Cachexia Indomethacin 4.4311239499 15141370 16537180 15625704
MESH:D002105 Cadmium Poisoning Quercetin 4.9616962696
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 8.0816192424 15700767 10355542 16011737 15721981 16124888 3786805 16097048 15673190 16050911 16227642 18705752
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 8.0816050911
MESH:D002276 Carcinoid Tumor Doxorubicin 10.4016051944
MESH:D002276 Carcinoid Tumor Fluorouracil 10.4016051944
MESH:D002277 Carcinoma Curcumin 11.3118593918
MESH:D002277 Carcinoma Fluorouracil 11.3117121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 11.3116835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.5716168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 39.0016705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 39.007296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 39.003084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 39.0011135700 16217749 14691202 15073043 15553829
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 39.0018788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 39.0017982673
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 39.0017876044 18059187 16234567 16023760
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 39.0016270382 17159502
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 39.0016799960 17088986 18930000 16332177 17971768 17045692
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 39.0016391822
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 39.0016313753
MESH:D006528 Carcinoma, Hepatocellular Quercetin 39.0012508355 19519916
MESH:D006528 Carcinoma, Hepatocellular resveratrol 39.0016227395 19321006
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 39.0016507464 15276417 17306315
MESH:D006528 Carcinoma, Hepatocellular Thalidomide 39.0016313753
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 39.001917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.4117123778
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 9.5211053908
MESH:D018827 Carcinoma, Lewis Lung resveratrol 9.5216675471
MESH:D018276 Carcinoma, Medullary Indomethacin 4.7814736730 18791128 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 7.7416685392 12023789
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 7.7418414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung sulindac sulfide 7.7412391285
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.3917234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.2919014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 12.897296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 12.8916201981 1485588
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 12.8918695887
MESH:D002292 Carcinoma, Renal Cell Indomethacin 12.8917341418
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.6112490120
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 30.016189445 17066447 18337622
MESH:D002294 Carcinoma, Squamous Cell Curcumin 30.0118462866
MESH:D002294 Carcinoma, Squamous Cell decitabine 30.0119215824
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 30.016189445
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 30.0116274795
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 30.0116757204 17066447 16280240 18986760
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 30.0115482327 12636206
MESH:D002294 Carcinoma, Squamous Cell resveratrol 30.0116227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 30.0118572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 30.0116096774 16051514
MESH:D006332 Cardiomegaly Quercetin 5.6519794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.6516120746 18850075 18670907
MESH:D009202 Cardiomyopathies Doxorubicin 3.1417924179 16455267 16952015 16242529 17382496 17007740 17928571 15476868 16612575 17308081 15811867 17351982 15792986 16109756 16278810 15505089 17974986 16364871 16731534 17329180 17519947 17131338 16651473 18627295 16269455
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.7216243910 17334414
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 6.2216936243
MESH:D002318 Cardiovascular Diseases resveratrol 6.2215458977
MESH:D002386 Cataract Acetaminophen 6.0210977129
MESH:D002386 Cataract Tretinoin 6.0217460283
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 5.387505956
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 5.3820056578 19524636
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 11.0616154183
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 11.0616129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.1416835633
MESH:D018281 Cholangiocarcinoma Thalidomide 8.1418291259
MESH:D002764 Cholecystitis Indomethacin 4.5811181007
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 11.1619486331 9022650
MESH:D002779 Cholestasis Diosgenin 11.1616105132
MESH:D002779 Cholestasis pirinixic acid 11.1619176532
MESH:D002822 Choriocarcinoma Tretinoin 4.5716461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 4.8512621046 15668235 15340226 8697196 16354765
MESH:D002972 Cleft Palate Tretinoin 4.859407595
MESH:D019970 Cocaine-Related Disorders Cocaine 5.1419606084
MESH:D003092 Colitis Curcumin 18.3218200517 16782535 16804969
MESH:D003092 Colitis resveratrol 18.3216474422
MESH:D003092 Colitis Thalidomide 18.3216680017
MESH:D003092 Colitis Tretinoin 18.3217035595
MESH:D003103 Coloboma Curcumin 4.0318809619
MESH:D003110 Colonic Neoplasms Butyrates 21.1915936596
MESH:D003110 Colonic Neoplasms Curcumin 21.1916340194 19359593
MESH:D003110 Colonic Neoplasms decitabine 21.1917616700
MESH:D003110 Colonic Neoplasms Fluorouracil 21.1917725105 16510598 17287894 15001691 17169374 18772588 17172411 16340194 17016597 17018589
MESH:D003110 Colonic Neoplasms Indomethacin 21.1915786552 15625704 15963497 15936596 15637740 11260862
MESH:D003110 Colonic Neoplasms irinotecan 21.1917725105 17287894
MESH:D003110 Colonic Neoplasms oxaliplatin 21.1916510598 16004971 16024531
MESH:D003110 Colonic Neoplasms Quercetin 21.1911134977 17191121 19440933 17148506 15741050 16640504 19056647
MESH:D003110 Colonic Neoplasms resveratrol 21.1916338953
MESH:D015179 Colorectal Neoplasms arsenic trioxide 20.7720501625
MESH:D015179 Colorectal Neoplasms Cisplatin 20.7715273666
MESH:D015179 Colorectal Neoplasms decitabine 20.7718981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 20.7718802399 18259882
MESH:D015179 Colorectal Neoplasms Fenretinide 20.7717273769
MESH:D015179 Colorectal Neoplasms Fluorouracil 20.7715148649 14970324 17401013 15289873 18448328 17255274 16331619 17594712 16391804 18383874 17695437 18949393 20501625 16303861 18802399 17094418 16282729 18288408 16524972 17454858 17016601 18509181
MESH:D015179 Colorectal Neoplasms Indomethacin 20.7718059344 17054584 12606626 11197048
MESH:D015179 Colorectal Neoplasms irinotecan 20.7715273666 16391804 17454858 18259882 18509181 16303861 17159606
MESH:D015179 Colorectal Neoplasms oxaliplatin 20.7718448328 18509181 17255274 17695437 17401013 17594712
MESH:D015179 Colorectal Neoplasms Paclitaxel 20.7718802399
MESH:D015179 Colorectal Neoplasms Quercetin 20.7718852136 18095365
MESH:D015179 Colorectal Neoplasms resveratrol 20.7716550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.5714669216 17141729
MESH:D016510 Corneal Neovascularization Curcumin 10.7418497527
MESH:D016510 Corneal Neovascularization Thalidomide 10.749301478
MESH:D003327 Coronary Disease resveratrol 3.3616507316
MESH:D023903 Coronary Restenosis arsenic trioxide 3.6412609071
MESH:D018352 Coronavirus Infections Indomethacin 5.1317302372
MESH:D003389 Cranial Nerve Diseases Thalidomide 5.729200351
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 8.3210525206
MESH:D019465 Craniofacial Abnormalities imatinib 8.3218322153
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 8.3210048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Thalidomide 8.329200351
MESH:D019465 Craniofacial Abnormalities Tretinoin 8.329125849 8800419 9142499 10589399 14991402 17551590 9664655 16925845 9224671 9211117
MESH:D019465 Craniofacial Abnormalities Vitamin E 8.3219769572
MESH:D003424 Crohn Disease Thalidomide 3.8616078585
MESH:D003456 Cryptorchidism vinclozolin 3.7914966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.4518551238
MESH:D007644 Darier Disease Fluorouracil 4.2216733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.5615213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 5.3412868966 11906362 11298694 8156756 2524372 8970840 14531868 18759878
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 5.3411298694 16823706 16780908
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.1318249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 2.962952479 3621924
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 6.9919496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 6.9916873680
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 3.8218403477
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 3.8217107852
MESH:D003928 Diabetic Nephropathies Curcumin 7.6218204486
MESH:D003928 Diabetic Nephropathies resveratrol 7.6216286809
MESH:D003967 Diarrhea Indomethacin 6.787907874 7237001
MESH:D003967 Diarrhea vorinostat 6.7820479100
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 12.5021346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 12.506679447 11289319 18692083 7440962 9653073 8291058 18648102 6482804 18289764 1440618 16192314 9328219 9022650
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 12.5019370779 19416960 12392966 16081117 16485898 11461765 10774834 18071297 11421492 16109766 16393943 14986274 15968718 12958197 17562736 19085960 17522070 12705907 10915739 16177239 19923254 16227642 19739265 11834606 19164858 16781746 11739529 14725611 18713872 17906064 11287661 14550746 10663392 11529661 12594235 12153990 15619225 2444490 19420014 12540782 11743745
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 12.5010915739 6884620 7440962 11566570 21278145 17522070 9327722 15998439 15968718 15027814 19085960 10092053 16177239 4309450 2869522 7120509 3786805 7179309 19336974 6623471 16227642 3732212
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 12.5017416283
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 12.5020420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.5119426721
MESH:D004362 Drug Toxicity Cisplatin 11.2512231392 19839026 15033597 12649298
MESH:D004362 Drug Toxicity Doxorubicin 11.2518602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 11.2511462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.5716133044 18446180 16326151 18043480 17190690 12774134
MESH:D004381 Duodenal Ulcer Curcumin 7.6117351913
MESH:D004381 Duodenal Ulcer Indomethacin 7.6117045617 11991626 17329845 16699067 11535926 17351913 11595415 10671773 17151854 11595431 17202747
MESH:C538011 Eales disease Vitamin E 4.129068938
MESH:D004487 Edema imatinib 16.2819703484
MESH:D004487 Edema Indomethacin 16.2816100529 8985016 7907874 19703484 8273558 7990266 10653021
MESH:D004487 Edema pirinixic acid 16.2812083418
MESH:D004487 Edema resveratrol 16.288985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 16.2811000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.0016714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 10.0018230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental 15-deoxy-delta(12,14)-prostaglandin J2 8.0016844232
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 8.0017872969
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.5319294695
MESH:D016889 Endometrial Neoplasms Doxorubicin 6.2717359293
MESH:D016889 Endometrial Neoplasms Tretinoin 6.2716569247
MESH:D004715 Endometriosis Indomethacin 7.4115652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.419294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.5718037988
MESH:D019446 Endotoxemia Indomethacin 3.9318509659
MESH:D004751 Enteritis Indomethacin 4.1610567023 16328016 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 10.5117980183
MESH:D020345 Enterocolitis, Necrotizing resveratrol 10.5117923197
MESH:D004802 Eosinophilia Indomethacin 3.5011298111
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 15.013581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 15.0112903497
MESH:D004938 Esophageal Neoplasms Cisplatin 15.0115173087 16785472 15464296 17638652 16481741
MESH:D004938 Esophageal Neoplasms Fluorouracil 15.0117638652 15173087 16481741 16337965 16785472
MESH:D004938 Esophageal Neoplasms Indomethacin 15.0111005569
MESH:D004938 Esophageal Neoplasms Paclitaxel 15.0116481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.3811564622
MESH:D005124 Eye Abnormalities Tretinoin 7.3816938888 9664655
MESH:D005221 Fatigue vorinostat 5.0220479100
MESH:D005234 Fatty Liver arsenic trioxide 14.5915073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 14.5915959796 19224547 12795759 16239168 12631006 17595544 16045604 61145
MESH:D005234 Fatty Liver Curcumin 14.5919297423
MESH:D005234 Fatty Liver pirinixic acid 14.5920131406 19236843
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.9011858732
MESH:D005334 Fever Indomethacin 3.6217627676 10431976 11852909
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.436705139
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 10.0719069698
MESH:D018222 Fibromatosis, Aggressive imatinib 10.0717453242
MESH:D005354 Fibrosarcoma Indomethacin 4.3210962813
MESH:D005355 Fibrosis Carbon Tetrachloride 27.2818705752
MESH:D005355 Fibrosis Curcumin 27.2818705752
MESH:D005355 Fibrosis Indomethacin 27.2817994277
MESH:D005355 Fibrosis Quercetin 27.2819474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 27.2820067830
MESH:D005355 Fibrosis Tretinoin 27.2817994277
MESH:D005499 Folliculitis Indomethacin 4.5811298111
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.7116904648
MESH:D005756 Gastritis Acetaminophen 9.2016983495
MESH:D005756 Gastritis Indomethacin 9.2015046732
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.1318462866
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.3616973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.7116417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.1016452187
MESH:D005871 Giant Lymph Node Hyperplasia Thalidomide 5.7212701121
MESH:D005909 Glioblastoma Curcumin 22.6717596214
MESH:D005909 Glioblastoma Doxorubicin 22.6717150277
MESH:D005909 Glioblastoma Fenretinide 22.6716187019
MESH:D005909 Glioblastoma Indomethacin 22.6712870263
MESH:D005909 Glioblastoma Quercetin 22.6719804834
MESH:D005909 Glioblastoma Tretinoin 22.6717312396
MESH:D005910 Glioma Fluorouracil 12.0216145905
MESH:D005910 Glioma Indomethacin 12.0216487511 18371953
MESH:D005910 Glioma Quercetin 12.0217643826
MESH:D005910 Glioma Thalidomide 12.0216327979
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.8211849393
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.507505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.0110696789
MESH:D006073 Gout Indomethacin 4.7811248219
MESH:D006258 Head and Neck Neoplasms Cisplatin 30.1015464296 15102660
MESH:D006258 Head and Neck Neoplasms Curcumin 30.1018829502 18462866
MESH:D006258 Head and Neck Neoplasms decitabine 30.1019215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 30.1015692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 30.1015162350 15102660 18337622
MESH:D006258 Head and Neck Neoplasms Indomethacin 30.1015482327
MESH:D006258 Head and Neck Neoplasms Tretinoin 30.1016096774
MESH:D034381 Hearing Loss Cisplatin 3.8119898482
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.5716084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.9415464296
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 9.2111294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 9.2114991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin E 9.2116080930
MESH:D006331 Heart Diseases Doxorubicin 3.0818006777 12587719 16879835 17888722 14766674 16144979 16495754 16244371 16707910 17875725 16244372 18674790 16330681
MESH:D006333 Heart Failure Doxorubicin 5.8017481944
MESH:D006333 Heart Failure pirinixic acid 5.8020558911
MESH:D006394 Hemangiosarcoma Doxorubicin 3.3915692506
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.8211000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.0515633222
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 7.426705139
MESH:D006505 Hepatitis Carbon Tetrachloride 7.4219110552 19900420
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.1415135802
MESH:D006529 Hepatomegaly pirinixic acid 6.4119176532 19772884 16221962 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 6.4115340226 16120746 12621046
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.4817701891
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.4716490937 16863852
MESH:D006561 Herpes Simplex Etoposide 8.2010809021
MESH:D006561 Herpes Simplex resveratrol 8.2016876885
MESH:D015658 HIV Infections beta Carotene 3.7216960176
MESH:D006689 Hodgkin Disease Cisplatin 13.5616170182 16200630
MESH:D006689 Hodgkin Disease Doxorubicin 13.5618501091 17606976 15147373
MESH:D006689 Hodgkin Disease Etoposide 13.5615147373 16200630 17606976 16135485 18180244
MESH:D006689 Hodgkin Disease sodium arsenite 13.5612676792
MESH:D019584 Hot Flashes Vitamin E 3.3914716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.4616354765 8697196 18606429 16959395 15340226
MESH:D006930 Hyperalgesia Acetaminophen 14.9516870215
MESH:D006930 Hyperalgesia Indomethacin 14.9512727271
MESH:D006930 Hyperalgesia oxaliplatin 14.9517418472
MESH:D006930 Hyperalgesia Tretinoin 14.9516870215
MESH:D034321 Hyperamylasemia Indomethacin 5.1317883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.9616899240
MESH:D006937 Hypercholesterolemia Curcumin 7.6718704882
MESH:D006937 Hypercholesterolemia resveratrol 7.6717188708
MESH:D006940 Hyperemia Indomethacin 4.4312524144
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.0116778211
MESH:D006943 Hyperglycemia pirinixic acid 7.5820558911
MESH:D006943 Hyperglycemia Quercetin 7.5818262572 11834736
MESH:D006949 Hyperlipidemias Indomethacin 7.7317546600
MESH:D006949 Hyperlipidemias resveratrol 7.7316873680
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.3815034207
MESH:D006973 Hypertension Quercetin 4.3818356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.3818850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.5315338365
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.8017488730
MESH:D007077 Ileal Diseases Indomethacin 4.4410574470 18306037
MESH:D007079 Ileitis Indomethacin 4.7816133968 10651667 10647630
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.7816133044
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.0917600658
MESH:D007248 Infertility, Male decitabine 8.9817581917
MESH:D007248 Infertility, Male sodium arsenite 8.9815346721 12646999
MESH:D007248 Infertility, Male vinclozolin 8.9816467254
MESH:D007249 Inflammation Curcumin 12.4116956363 17151092 18403477
MESH:D007249 Inflammation Indomethacin 12.413291741 7812673 12568917
MESH:D007249 Inflammation resveratrol 12.4116366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 12.4112200463 12878042
MESH:D007249 Inflammation Thalidomide 12.4116134734
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.9518200517 18596194
MESH:D007251 Influenza, Human Quercetin 15.2816624496
MESH:D007251 Influenza, Human resveratrol 15.2816624496
MESH:D007251 Influenza, Human Vitamin E 15.2816624496
MESH:D007333 Insulin Resistance bisphenol A 6.0016393666
MESH:D007333 Insulin Resistance pirinixic acid 6.0016306350
MESH:D007410 Intestinal Diseases Indomethacin 8.0318236018 17329856 15610444 11713966 17994277 15831440 11855677 11686837 10210152
MESH:D007410 Intestinal Diseases Tretinoin 8.0317994277
MESH:D007414 Intestinal Neoplasms Curcumin 3.7210783313
MESH:D019586 Intracranial Hypertension Indomethacin 4.7815241188
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.439022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.2216580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.2217551590 15992940
MESH:D007579 Jejunal Diseases Indomethacin 4.4416133968 10574470 18306037
MESH:D007627 Keloid Quercetin 4.3917086741
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.5515464296
MESH:D007674 Kidney Diseases Acetaminophen 23.3912587719 15629191
MESH:D007674 Kidney Diseases Cisplatin 23.3912649298 12231392 15190930 19839026 18289764
MESH:D007674 Kidney Diseases Doxorubicin 23.3915699352 15369732 16775033
MESH:D007674 Kidney Diseases Indomethacin 23.3917190690
MESH:D007674 Kidney Diseases Quercetin 23.3916962696
MESH:D007674 Kidney Diseases sodium arsenite 23.3920008137
MESH:D007674 Kidney Diseases Vitamin E 23.3912488133
MESH:D007676 Kidney Failure, Chronic Doxorubicin 8.4116707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 8.4116518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 9.7216705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 9.726582329
MESH:D007680 Kidney Neoplasms Fluorouracil 9.7216985049
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.2111231351
MESH:D007889 Leiomyoma Curcumin 4.0418555241
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.4411703811 12228301 10320625
MESH:D007898 Leishmaniasis, Visceral Thalidomide 3.9016514283
MESH:D007938 Leukemia marker/mechanism 12970779
MESH:D007938 Leukemia 1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate 29.4312970779
MESH:D007938 Leukemia 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 29.4312970779
MESH:D007938 Leukemia arsenic trioxide 29.4315070760
MESH:D007938 Leukemia Curcumin 29.4318462866
MESH:D007938 Leukemia decitabine 29.4318980019 19235587
MESH:D007938 Leukemia Quercetin 29.4317468513
MESH:D007938 Leukemia SN50 peptide 29.4312970779
MESH:D007938 Leukemia Tretinoin 29.4317143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.5716085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 8.0517077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 8.0516106398
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.7316972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 16.5514633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive imatinib 16.5519208803 17301526 15107311 15748426
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 16.5515631656 16572323 10785260
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive tetraarsenic tetrasulfide 16.5519208803
MESH:D007951 Leukemia, Myeloid arsenic trioxide 18.6419077051
MESH:D007951 Leukemia, Myeloid decitabine 18.6419117987 17236224 18454857
MESH:D007951 Leukemia, Myeloid imatinib 18.6417236224
MESH:D007951 Leukemia, Myeloid Tretinoin 18.6416482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 10.1816968895 16467208 17050201 19850784 20471514
MESH:D015470 Leukemia, Myeloid, Acute decitabine 10.1818460780 18206229 18704418 19387464 17679729 19010910
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 10.1818360721
MESH:D015470 Leukemia, Myeloid, Acute Thalidomide 10.1818720364
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 10.1819850784 17596541 16294345
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.8718055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 10.4915748426 15213294 16331271 19225113 17107899 12679006 15336539 12018890 12712474 17217047 17712046 15622746 16330433 16891316 19642359 17869043 19075265 16823087 17649720 16966277 9834237 11161223 11468182 16112521 19035177
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 10.4916087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 10.4916891316 17368321 17361223 12679006 16823087 16331271 17294898 17301526 16788101 16935935 17649720 19075265 9834237 15748426 19035177 17506722 19642359 16766008 17339181 19029980 17217047 19225113 17107899 17712046 16140955
MESH:D015458 Leukemia, T-Cell arsenic trioxide 9.9016882451
MESH:D015458 Leukemia, T-Cell Curcumin 9.9016106398
MESH:D007964 Leukocytosis Indomethacin 4.7816537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.1317980183
MESH:D007972 Leukoplakia, Oral Fenretinide 5.4616707609
MESH:D007984 Leydig Cell Tumor vinclozolin 4.1616417039
MESH:D017880 Limb Deformities, Congenital Thalidomide 7.1410473037
MESH:D017880 Limb Deformities, Congenital Tretinoin 7.149224671
MESH:D008080 Liposarcoma Paclitaxel 4.2917353645
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.1311479899
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 5.9016239168 16943688 21278145 17157831 17174718 16221502 11903743 17334410 11408273
MESH:D008103 Liver Cirrhosis Thalidomide 5.9017174718 16943688
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.8215034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 18.4818205269 18251166 11481614 16192424 12445421 18472332 17640975 18395914 16011737 12586293 15362042 16248980 15057751 18210741 18705752 15818738 15876570 12741479 18418968 12898905 12667390 17708605 17525996 15338365 18156304 17761835 17976157 15931870 18166357 15730626 18429990 18277467 18481824 12958196 15959796 18376398 17944888 17631135 16027843 18472094 18263696 14748882 14716833 15123356 18187930 12632512 18339082 12546737 17766677 15673190 17721639 17557913 16033810 18412020 10355542 17922224 14724832 12649538 18279442 17481882 17900296 17805973 16097048 16136751 18395095 15996030 12609069 12632514 20821823 17869086 18420326 16638106 13678700 17714472 12389079 14620537 16116963 15052691 18054572 17565644 18317297 12445418 14512876 15925388 16015684 18006644 12666154 15370692 15893842 17698563 17823541 14716496 15650968
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 18.4817355460 18006644 18705752
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 18.4816439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental imatinib 18.4816596278
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 18.4818194892
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 18.4815474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 18.4812741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 18.4812878042
MESH:D008106 Liver Cirrhosis, Experimental Thalidomide 18.4815465738
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 18.4816248980 18397230
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 18.4816169303
MESH:D008107 Liver Diseases Acetaminophen 5.4519014921 16611625 12969438 16610002 19460945 19784758 11587558 12587719
MESH:D008107 Liver Diseases Carbon Tetrachloride 5.4515720792 17285989 15830285 16246199 16964402
MESH:D008107 Liver Diseases Curcumin 5.4516956363
MESH:D017093 Liver Failure Carbon Tetrachloride 3.6015123358
MESH:D017114 Liver Failure, Acute Acetaminophen 7.7417185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 7.7416899240 14706259
MESH:D008113 Liver Neoplasms arsenic trioxide 25.0414682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 25.0419294768
MESH:D008113 Liver Neoplasms Fluorouracil 25.0418383874 17045692 15113037 16603448
MESH:D008113 Liver Neoplasms pirinixic acid 25.0420007298 15890375 16377806
MESH:D008113 Liver Neoplasms Quercetin 25.0418980244
MESH:D008113 Liver Neoplasms resveratrol 25.0419321006 19812893 20405173 19073162
MESH:D008113 Liver Neoplasms sodium arsenite 25.0415276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 25.0416984957
MESH:D008113 Liver Neoplasms zerumbone 25.0420452335
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 22.456587162 3712494 598648 1399818
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 22.4520377131
MESH:D008114 Liver Neoplasms, Experimental beta Carotene 22.4517113696
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 22.4512014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 22.4516842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Quercetin 22.4519519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 22.4512151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.9115213294
MESH:D008171 Lung Diseases sodium arsenite 6.1019095001
MESH:D008171 Lung Diseases Vitamin E 6.1016863852
MESH:D008175 Lung Neoplasms arsenic trioxide 18.1419825857 11798837
MESH:D008175 Lung Neoplasms beta Carotene 18.1416401635
MESH:D008175 Lung Neoplasms Cisplatin 18.1411798837 6189445 17225452
MESH:D008175 Lung Neoplasms Curcumin 18.1419359593 16243823 18462866
MESH:D008175 Lung Neoplasms Doxorubicin 18.1417418594 6189445
MESH:D008175 Lung Neoplasms Fluorouracil 18.1415246190
MESH:D008175 Lung Neoplasms Indomethacin 18.1411053908 11497255 16537180
MESH:D008175 Lung Neoplasms Quercetin 18.1416280456
MESH:D008175 Lung Neoplasms sodium arsenite 18.1417306315 15276417 16712894 17077188 19931552
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 18.1419555203 11884234
MESH:D008175 Lung Neoplasms Vitamin E 18.1411062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.2215086387
MESH:D008223 Lymphoma Curcumin 14.4618462866
MESH:D008223 Lymphoma decitabine 14.4619470736
MESH:D008223 Lymphoma Doxorubicin 14.4616098063
MESH:D008223 Lymphoma Etoposide 14.4612854902 12556972
MESH:D016393 Lymphoma, B-Cell resveratrol 3.7717088997
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 11.9017654614
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 11.9014749477
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 11.9014749477
MESH:D016399 Lymphoma, T-Cell 3-(4-methylphenylsulfonyl)-2-propenenitrile 16.3716173963
MESH:D016399 Lymphoma, T-Cell Curcumin 16.3716173963
MESH:D016399 Lymphoma, T-Cell Doxorubicin 16.3715621674
MESH:D016410 Lymphoma, T-Cell, Cutaneous vorinostat 5.1220479100
MESH:D015674 Mammary Neoplasms, Animal resveratrol 3.6815688416
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 7.9515458769
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 7.9510697514
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 7.958985016 11606380
MESH:D008527 Medulloblastoma Tretinoin 2.5317453147
MESH:D008545 Melanoma Cisplatin 21.8512883367 17761969 11135225 15577323 17023156 16248763 18332650 12393984 16432458 18176117 18505091 16809738 12374674
MESH:D008545 Melanoma Curcumin 21.8517885582 18462866
MESH:D008545 Melanoma decitabine 21.8516505122 17785578
MESH:D008545 Melanoma Doxorubicin 21.8516827129
MESH:D008545 Melanoma Fenretinide 21.8516270382
MESH:D008545 Melanoma Paclitaxel 21.8516342250 12040289 12025231
MESH:D008545 Melanoma resveratrol 21.8517992120
MESH:D008545 Melanoma sodium arsenite 21.8516487513 19082730
MESH:D008545 Melanoma Thalidomide 21.8512829675 16098027 17089043
MESH:D008545 Melanoma Tretinoin 21.8516752155
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.2015990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.0119513568
MESH:D008569 Memory Disorders Curcumin 3.6117263510
MESH:D008591 Meningomyelocele Tretinoin 3.8616940565
MESH:D008654 Mesothelioma Cisplatin 5.5817638057
MESH:D008654 Mesothelioma Doxorubicin 5.5817638057
MESH:D008659 Metabolic Diseases resveratrol 3.8617112576
MESH:D008881 Migraine Disorders Indomethacin 3.2611903285
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.9815792986
MESH:D009062 Mouth Neoplasms Fenretinide 11.9816274795
MESH:D009062 Mouth Neoplasms Fluorouracil 11.9818986760 16757204
MESH:D009062 Mouth Neoplasms Indomethacin 11.9812636206
MESH:D052016 Mucositis Doxorubicin 10.5117415656
MESH:D052016 Mucositis irinotecan 10.5117159606
MESH:D009101 Multiple Myeloma arsenic trioxide 27.5814977855 11468182 15949261 19549372 19417148
MESH:D009101 Multiple Myeloma Curcumin 27.5819372569
MESH:D009101 Multiple Myeloma decitabine 27.5818172295
MESH:D009101 Multiple Myeloma lonafarnib 27.5816996129
MESH:D009101 Multiple Myeloma Paclitaxel 27.5814749477
MESH:D009101 Multiple Myeloma resveratrol 27.5817049120 16490592 14749477 16267019 17164350 17935668
MESH:D009101 Multiple Myeloma Thalidomide 27.5815744524 16445831 15741222 19112201 19372569 17168659 15920492 19112817 15867202 15939924
MESH:D009134 Muscular Atrophy, Spinal Curcumin 10.5017962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 10.5017962980
MESH:D009135 Muscular Diseases pirinixic acid 2.9516239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.0918349030
MESH:D009190 Myelodysplastic Syndromes marker/mechanism 16105982
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 14.7116882451 16105982
MESH:D009190 Myelodysplastic Syndromes decitabine 14.7119010910 16882708 19157545 18608210
MESH:D009190 Myelodysplastic Syndromes Thalidomide 14.7118720364
MESH:D009190 Myelodysplastic Syndromes Tretinoin 14.7117596541
MESH:D009203 Myocardial Infarction Cocaine 14.9918072171
MESH:D009203 Myocardial Infarction Doxorubicin 14.9915857846 19429709
MESH:D009203 Myocardial Infarction pirinixic acid 14.9919151258
MESH:D009203 Myocardial Infarction Quercetin 14.9919595682
MESH:D009203 Myocardial Infarction resveratrol 14.9917188708 16317513 17125593 16456233 16525036 17015251
MESH:D017202 Myocardial Ischemia resveratrol 7.4717125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 7.4712213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 6.9516411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 6.9519207477
MESH:D009205 Myocarditis resveratrol 4.1817322642
MESH:D009325 Nausea vorinostat 4.9420479100
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.2918551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 8.5116624393
MESH:D009361 Neoplasm Invasiveness Curcumin 8.5118495463
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 19.043581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 19.0418259882
MESH:D009362 Neoplasm Metastasis imatinib 19.0415867366
MESH:D009362 Neoplasm Metastasis Indomethacin 19.0416537180 11239499 11053908
MESH:D009362 Neoplasm Metastasis irinotecan 19.0418259882
MESH:D009362 Neoplasm Metastasis Paclitaxel 19.0415867366
MESH:D009369 Neoplasms beta Carotene 26.6517051425
MESH:D009369 Neoplasms Cisplatin 26.6516773208
MESH:D009369 Neoplasms decitabine 26.6519470736 19116145 17925555
MESH:D009369 Neoplasms Fenretinide 26.6515958647 17353921
MESH:D009369 Neoplasms Fluorouracil 26.6518600527 18239605 16928823
MESH:D009369 Neoplasms pirinixic acid 26.6517405874
MESH:D009369 Neoplasms Quercetin 26.6515185748
MESH:D009369 Neoplasms sodium arsenite 26.6511559025
MESH:D009369 Neoplasms Tretinoin 26.6516946489 16594593
MESH:D009374 Neoplasms, Experimental Indomethacin 12.1315625704 10663608
MESH:D009374 Neoplasms, Experimental resveratrol 12.138985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 12.1320056578
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 9.4412497104
MESH:D009376 Neoplasms, Hormone-Dependent imatinib 9.4417614352
MESH:D009395 Nephritis, Interstitial Cisplatin 3.9115464296
MESH:D009401 Nephrosis Doxorubicin 4.2116899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.5115640375 16889571
MESH:D009421 Nervous System Malformations bisphenol A 19.0316427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 19.0314600291
MESH:D009421 Nervous System Malformations Thalidomide 19.0316859833
MESH:D009421 Nervous System Malformations Tretinoin 19.039125849
MESH:D009423 Nervous System Neoplasms Curcumin 5.0418462866
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 14.096679447
MESH:D009436 Neural Tube Defects arsenic trioxide 14.0910525206
MESH:D009436 Neural Tube Defects sodium arsenite 14.0912854658
MESH:D009436 Neural Tube Defects Tretinoin 14.099142499
MESH:D009447 Neuroblastoma Cisplatin 9.648761367
MESH:D009447 Neuroblastoma Doxorubicin 9.6415555623
MESH:D009447 Neuroblastoma irinotecan 9.648761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 11.4018514411
MESH:D019636 Neurodegenerative Diseases Indomethacin 11.4012349958
MESH:D019636 Neurodegenerative Diseases resveratrol 11.4017652729
MESH:D017599 Neuroectodermal Tumors Cisplatin 9.568761367
MESH:D017599 Neuroectodermal Tumors irinotecan 9.568761367
MESH:D020078 Neurogenic Inflammation Quercetin 8.9317929310
MESH:D020078 Neurogenic Inflammation resveratrol 8.9317929310
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 5.1016303764
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.0316436463
MESH:D009765 Obesity Curcumin 4.0119297423
MESH:D009765 Obesity pirinixic acid 4.0120558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.586374098
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 7.2216049721 12819281
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 7.224026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.433988306
MESH:D010003 Osteoarthritis Indomethacin 3.307009135
MESH:D010014 Osteolysis imatinib 10.5115867366
MESH:D010014 Osteolysis Paclitaxel 10.5115867366
MESH:D010024 Osteoporosis Curcumin 3.1018719352
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 8.4419495926
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 8.4417513867
MESH:D012516 Osteosarcoma Doxorubicin 3.6515930896
MESH:D010049 Ovarian Diseases bisphenol A 4.4111985600
MESH:D010051 Ovarian Neoplasms 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 35.2016211241
MESH:D010051 Ovarian Neoplasms arsenic trioxide 35.2016624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Cisplatin 35.2017225452 15464296 19769630 6897625
MESH:D010051 Ovarian Neoplasms Curcumin 35.2019020741 18462866
MESH:D010051 Ovarian Neoplasms decitabine 35.2019331143 19259094
MESH:D010051 Ovarian Neoplasms Fenretinide 35.2016133793
MESH:D010051 Ovarian Neoplasms Paclitaxel 35.2011161223
MESH:D010051 Ovarian Neoplasms Quercetin 35.2019005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 35.2017306315 15276417
MESH:D010051 Ovarian Neoplasms Thalidomide 35.2016288038
MESH:D010051 Ovarian Neoplasms Tretinoin 35.2016936753
MESH:D010146 Pain Acetaminophen 8.5716870215
MESH:D010146 Pain Indomethacin 8.5717627676 17440234 3291741 13679232
MESH:D010146 Pain Tretinoin 8.5716870215
MESH:D010149 Pain, Postoperative Indomethacin 4.1012538197 18702446
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 33.4015580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 33.4019003803
MESH:D010190 Pancreatic Neoplasms Curcumin 33.4017440100 19196508 19401701
MESH:D010190 Pancreatic Neoplasms decitabine 33.4019294695
MESH:D010190 Pancreatic Neoplasms dehydroxymethylepoxyquinomicin 33.4016211219
MESH:D010190 Pancreatic Neoplasms Etoposide 33.4019003803
MESH:D010190 Pancreatic Neoplasms Fenretinide 33.4015580305
MESH:D010190 Pancreatic Neoplasms Fluorouracil 33.4016929163 15113037 16500647 19003803
MESH:D010190 Pancreatic Neoplasms Quercetin 33.4016965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 33.4015976015
MESH:D010195 Pancreatitis Indomethacin 3.4015028970 17883296
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 7.467296757
MESH:D010212 Papilloma Hydrogen Peroxide 7.4612065085
MESH:D010235 Paraganglioma arsenic trioxide 3.6319927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.1316537180
MESH:D010291 Paresis Thalidomide 5.729200351
MESH:D020734 Parkinsonian Disorders Indomethacin 3.6212349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.1311903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.6612520081
MESH:D010437 Peptic Ulcer Indomethacin 4.5711148446
MESH:D010518 Periodontitis Indomethacin 4.3317225004
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.7715464296
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 3.886228378
MESH:D003557 Phyllodes Tumor Doxorubicin 4.5717983394
MESH:D010997 Pleural Neoplasms Cisplatin 11.9917638057
MESH:D010997 Pleural Neoplasms Doxorubicin 11.9917638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.0118163543
MESH:D011230 Precancerous Conditions Quercetin 3.4919056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma imatinib 7.1612476293
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Thalidomide 7.1617031469
MESH:D047928 Premature Birth Indomethacin 4.5617000239
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 18.5610548101
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 18.5616679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 18.5611896295 11222880 11118676 11399792
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 18.5618220299 19015723 18042343
MESH:D055728 Primary Myelofibrosis decitabine 4.1717616702
MESH:D011469 Prostatic Diseases vinclozolin 4.3618220299
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 3.6920887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 7.1319131511
MESH:D011471 Prostatic Neoplasms bisphenol A 7.1316740699
MESH:D011471 Prostatic Neoplasms Curcumin 7.1311398177 10851300 18226269 18156803 15129424 12497104 18769126
MESH:D011471 Prostatic Neoplasms Doxorubicin 7.1315897917 16729912 16888761 18437689 16868541 15749863
MESH:D011471 Prostatic Neoplasms Etoposide 7.1317172428
MESH:D011471 Prostatic Neoplasms Fenretinide 7.1317024972
MESH:D011471 Prostatic Neoplasms Fluorouracil 7.1319082440 18626508
MESH:D011471 Prostatic Neoplasms Paclitaxel 7.1317172428 17136230 16356831 16729912
MESH:D011471 Prostatic Neoplasms Phellinus linteus extract 7.1316868541
MESH:D011471 Prostatic Neoplasms Quercetin 7.1317292933 14715546
MESH:D011471 Prostatic Neoplasms resveratrol 7.1316731767 17675339 17718901 17804756 15767336 17636462
MESH:D011471 Prostatic Neoplasms sodium arsenite 7.1316039940
MESH:D011471 Prostatic Neoplasms Thalidomide 7.1316729912
MESH:D011471 Prostatic Neoplasms Vitamin E 7.1315084515
MESH:D011471 Prostatic Neoplasms vorinostat 7.1317218635
MESH:D011472 Prostatitis vinclozolin 4.3618629315
MESH:D011507 Proteinuria Indomethacin 7.5811849393
MESH:D011507 Proteinuria Tretinoin 7.5816636307
MESH:D011536 Prurigo Thalidomide 5.7212755975
MESH:D011618 Psychotic Disorders Cocaine 4.4016134406
MESH:D011625 Pterygium Tretinoin 4.2216723453
MESH:D011629 Puberty, Precocious bisphenol A 4.2110548101
MESH:D011656 Pulmonary Emphysema Curcumin 4.0219168576
MESH:D012004 Rectal Neoplasms Fluorouracil 3.5218286688 15538739 16160472 18722050
MESH:D051437 Renal Insufficiency Cisplatin 8.5215464296
MESH:D051437 Renal Insufficiency Doxorubicin 8.5217922066
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.0016325855
MESH:D015427 Reperfusion Injury pirinixic acid 5.5319058328
MESH:D015427 Reperfusion Injury resveratrol 5.5316317513 17520802 15827377 16314181 17058453
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.5010666014 18379247
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.2918990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 7.653692021
MESH:D012162 Retinal Degeneration Fenretinide 7.6516303925
MESH:D012175 Retinoblastoma SN50 peptide 5.9212466137
MESH:D012208 Rhabdomyosarcoma decitabine 9.1819155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 9.1816116481 16283617
MESH:D012509 Sarcoma Curcumin 7.9018462866
MESH:D012509 Sarcoma Doxorubicin 7.9017710206 17203757 15675481 15625365 18313854 16767912
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 26.4816646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 26.4814601052
MESH:D012512 Sarcoma, Ewing's Dactinomycin 26.4814601052
MESH:D012512 Sarcoma, Ewing's Doxorubicin 26.4816326096 14601052
MESH:D012512 Sarcoma, Ewing's Etoposide 26.4814601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.2217846226
MESH:D012554 Schistosomiasis japonica Quercetin 4.9616862918
MESH:D019873 Schnitzler Syndrome Thalidomide 5.3616096327
MESH:D012640 Seizures 2,4-dinitrotoluene 5.0918551238
MESH:D012640 Seizures Cocaine 5.0910454489
MESH:D018805 Sepsis Curcumin 3.6018389075
MESH:D012871 Skin Diseases Vitamin E 2.2718709164
MESH:D012878 Skin Neoplasms Doxorubicin 22.5615692506
MESH:D012878 Skin Neoplasms Fenretinide 22.5616467112
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 22.5612065085
MESH:D012878 Skin Neoplasms resveratrol 22.568985016 15837718
MESH:D012878 Skin Neoplasms sodium arsenite 22.5619524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 22.5616192470
MESH:D012878 Skin Neoplasms Tretinoin 22.5616467112
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.7615464296
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.0117203757 16767912 15625365
MESH:D016135 Spinal Dysraphism sodium arsenite 3.3412854658
MESH:D013272 Stomach Diseases beta Carotene 8.7517638125
MESH:D013272 Stomach Diseases Indomethacin 8.7510486359 16113693 10215738 18209964 17160473 10192188 17207306 17638125 16184426 18545984 16280098 15038085 15472012
MESH:D013274 Stomach Neoplasms arsenic trioxide 13.3217007042
MESH:D013274 Stomach Neoplasms Cisplatin 13.3218396642 17522103 15958060
MESH:D013274 Stomach Neoplasms decitabine 13.3219037991
MESH:D013274 Stomach Neoplasms Fluorouracil 13.3216951190 18567086 18396642 15786421 16424979 17498489 19015929 17172411 17522103 19084572
MESH:D013274 Stomach Neoplasms imatinib 13.3215786421
MESH:D013274 Stomach Neoplasms Indomethacin 13.3215609394
MESH:D013274 Stomach Neoplasms irinotecan 13.3215723263
MESH:D013274 Stomach Neoplasms Paclitaxel 13.3218396642 18506536
MESH:D013274 Stomach Neoplasms Tretinoin 13.3217261132
MESH:D013276 Stomach Ulcer beta Carotene 13.1212500499
MESH:D013276 Stomach Ulcer Curcumin 13.1219188055 16631530
MESH:D013276 Stomach Ulcer Indomethacin 13.1218209962 10423059 11595431 10750652 12498302 17135157 16934674 1323529 18181030 16150113 12467913 16169175 11523592 18726076 14567935 12787963 11145282 18543354 18299717 11906479 11729361 10878458 18087811 18193104 17657623 17918041 18237397 17654042 18431645 16631530 12500499 17895592 16397915 17977527 15138204 15255614 16755016 16252198 17627676 12077510 11595415 15104355
MESH:D013276 Stomach Ulcer Thalidomide 13.1215138204
MESH:D020521 Stroke Vitamin E 3.0616517955
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.9816321402
MESH:D019966 Substance-Related Disorders bisphenol A 3.4116684133 16045194
MESH:D024801 Tauopathies Paclitaxel 4.2416930453
MESH:D013736 Testicular Neoplasms Cisplatin 4.1015464296 17225452
MESH:D013921 Thrombocytopenia vorinostat 4.4720479100
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.3212697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 31.856582329 6587162 1399818 7505956 3712494
MESH:D013964 Thyroid Neoplasms arsenic trioxide 31.8519014326
MESH:D013964 Thyroid Neoplasms Butyrates 31.8517967635
MESH:D013964 Thyroid Neoplasms decitabine 31.8517967635
MESH:D013964 Thyroid Neoplasms Doxorubicin 31.8516010429 17909728
MESH:D013964 Thyroid Neoplasms imatinib 31.8516940797
MESH:D013964 Thyroid Neoplasms Indomethacin 31.8514736730 18791128 11352223
MESH:D013964 Thyroid Neoplasms Tretinoin 31.8516026305 17045167
MESH:D014062 Tongue Neoplasms Fluorouracil 13.6816280240
MESH:D014062 Tongue Neoplasms resveratrol 13.6816227395
MESH:D014062 Tongue Neoplasms Tretinoin 13.6816051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.3915213294
MESH:D014376 Tuberculosis Tretinoin 2.8516040207
MESH:D014456 Ulcer Indomethacin 4.3210574470 17380554
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 31.9216049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 31.928074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 31.9212845720 12973940 20435036 11780464
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 31.9217225452 12973940 15464296
MESH:D001749 Urinary Bladder Neoplasms Curcumin 31.9218593936
MESH:D001749 Urinary Bladder Neoplasms decitabine 31.9219087683 17616700
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 31.9217653716
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 31.9216720286
MESH:D001749 Urinary Bladder Neoplasms Quercetin 31.9216720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 31.9216712894 16452187 11723127 17306315
MESH:D014565 Urogenital Neoplasms Curcumin 4.6918462866
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.7410091137
MESH:D014581 Urticaria Acetaminophen 2.4510982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 36.7316803524
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 36.7316154183
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 36.7316803524
MESH:D002583 Uterine Cervical Neoplasms indole-3-carbinol 36.7316082211
MESH:D002583 Uterine Cervical Neoplasms resveratrol 36.7317473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 36.7311813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 36.7316129372
MESH:D014591 Uterine Diseases bisphenol A 4.4214652134
MESH:D014594 Uterine Neoplasms resveratrol 8.1917044934
MESH:D014594 Uterine Neoplasms sulindac sulfide 8.1918645019
MESH:D014604 Uveal Neoplasms decitabine 10.8817785578
MESH:D014604 Uveal Neoplasms Tretinoin 10.8816752155
MESH:D014625 Vaginal Neoplasms Cisplatin 4.0515577323
MESH:D014652 Vascular Diseases sodium arsenite 10.2117056641
MESH:D014652 Vascular Diseases Thalidomide 10.2115741222
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.0112125929
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 8.4817334414 16364871 17678736 17638931
MESH:D018487 Ventricular Dysfunction, Left resveratrol 8.4817488730
MESH:D014820 Vitiligo Tretinoin 3.5116761959
MESH:D014839 Vomiting Cisplatin 9.5911897121
MESH:D014839 Vomiting Indomethacin 9.5911897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.6615886252
MESH:D009396 Wilms Tumor Tretinoin 3.4816287080
Pathway ID Pathway Name
KEGG:04210 Apoptosis
KEGG:05142 Chagas disease (American trypanosomiasis)
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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