AutismKB 2.0

Annotation Detail for FCGBP


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Basic Information Top
Gene Symbol:FCGBP ( FC(GAMMA)BP )
Gene Full Name: Fc fragment of IgG binding protein
Band: 19q13.2
Quick LinksEntrez ID:8857; OMIM: NA; Uniprot ID:FCGBP_HUMAN; ENSEMBL ID: ENSG00000090920; HGNC ID: 13572
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of FCGBP mRNAincreases expression 16788091
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of FCGBP proteinaffects expression 20106945
C014347 decitabine decitabine results in increased expression of FCGBP mRNAincreases expression 16367923
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of FCGBP mRNAincreases expression 15289156
D004958 Estradiol Estradiol results in increased expression of FCGBP mRNAincreases expression 15289156
D019833 Genistein Genistein results in increased expression of FCGBP mRNAincreases expression 15289156
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Estradiol 4.6811473722
MESH:D000230 Adenocarcinoma Genistein 4.6811473722
MESH:D000686 Amyloidosis Diethylstilbestrol 4.8615469931
MESH:D001943 Breast Neoplasms decitabine 2.0418320071 19208741
MESH:D001943 Breast Neoplasms Diethylstilbestrol 2.0415324884 17129689
MESH:D001943 Breast Neoplasms Estradiol 2.0416675129 17289903 17261762 12948864 19861407 14630087 17018787 18497071
MESH:D001943 Breast Neoplasms Genistein 2.0416873071 16541309 17200150
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.9316111702
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 6.9521507988 12619106 12907637
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 6.9516924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Estradiol 6.9516924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 6.9516924424
MESH:D002294 Carcinoma, Squamous Cell decitabine 2.6619215824
MESH:D002318 Cardiovascular Diseases Genistein 3.5116332659
MESH:D002471 Cell Transformation, Neoplastic Estradiol 2.9818566989
MESH:D003110 Colonic Neoplasms decitabine 4.0417616700
MESH:D003110 Colonic Neoplasms Genistein 4.0417182828
MESH:D015179 Colorectal Neoplasms decitabine 2.1018981723
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.9416002989 12952375
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 2.5416647724
MESH:D003928 Diabetic Nephropathies Estradiol 3.7019279558
MESH:D004701 Endocrine Gland Neoplasms decitabine 5.6419294695
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 13.4816402032
MESH:D004714 Endometrial Hyperplasia Genistein 13.4816402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 13.6616804899 15700306
MESH:D016889 Endometrial Neoplasms Estradiol 13.6619148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Genistein 13.6611473722
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.8316611131 15751030 16513791 16534752 16002989
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 5.4116452187
MESH:D005909 Glioblastoma Genistein 3.4516598420
MESH:D006258 Head and Neck Neoplasms decitabine 3.6919215824
MESH:D006558 Herpes Genitalis Estradiol 5.5515709030
MESH:D019584 Hot Flashes Estradiol 4.2717088409
MESH:D006965 Hyperplasia Diethylstilbestrol 4.8514722030 12960047
MESH:D007021 Hypospadias Diethylstilbestrol 5.0016002989
MESH:D007246 Infertility Diethylstilbestrol 4.7415036965
MESH:D007248 Infertility, Male decitabine 3.4017581917
MESH:D007333 Insulin Resistance Estradiol 3.1616627594 16393666
MESH:D007674 Kidney Diseases Estradiol 2.7415618244
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 8.4514681315 15003126 16762066
MESH:D007680 Kidney Neoplasms Estradiol 8.4515610895
MESH:D007859 Learning Disorders Diethylstilbestrol 4.4817184923
MESH:D007938 Leukemia decitabine 6.9818980019 19235587
MESH:D007938 Leukemia Genistein 6.9817468513 18980019
MESH:D007951 Leukemia, Myeloid decitabine 4.3317236224 18454857 19117987
MESH:D015470 Leukemia, Myeloid, Acute decitabine 2.4219010910 18206229 18460780 18704418 17679729 19387464
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.9818055864
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 2.6414659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 2.6417823541
MESH:D008113 Liver Neoplasms Aflatoxin B1 5.1115890375 18177683 9163691 2125692
MESH:D008113 Liver Neoplasms Diethylstilbestrol 5.1115890375 16712894
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 2.928603461
MESH:D008175 Lung Neoplasms Aflatoxin B1 1.8814755239
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.6115166399
MESH:D008223 Lymphoma decitabine 8.4719470736
MESH:D008223 Lymphoma Diethylstilbestrol 8.4715700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 6.0416002989
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 6.7211408345 11807958 17203775 16891317
MESH:D008325 Mammary Neoplasms, Experimental Genistein 6.7212929590 14578162
MESH:D020149 Manganese Poisoning Estradiol 5.0019453300
MESH:D008545 Melanoma decitabine 2.2816505122 17785578
MESH:D009101 Multiple Myeloma decitabine 3.5618172295
MESH:D009190 Myelodysplastic Syndromes decitabine 3.5419010910 16882708 18608210 19157545
MESH:D009203 Myocardial Infarction Genistein 2.9617141266
MESH:D015428 Myocardial Reperfusion Injury Estradiol 9.3316810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 9.3317141266
MESH:D009369 Neoplasms decitabine 5.7817925555 19116145 19470736
MESH:D009369 Neoplasms Diethylstilbestrol 5.7815313581
MESH:D009389 Neovascularization, Pathologic Estradiol 4.1917289903
MESH:D009421 Nervous System Malformations Diethylstilbestrol 18.8311399458
MESH:D009421 Nervous System Malformations Estradiol 18.8311399458 16427766
MESH:D009421 Nervous System Malformations Genistein 18.8316427766
MESH:D010024 Osteoporosis Genistein 3.4319401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 4.4416169203
MESH:D010051 Ovarian Neoplasms decitabine 8.4219331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 8.4219401270
MESH:D010051 Ovarian Neoplasms Genistein 8.4219005980
MESH:D010190 Pancreatic Neoplasms decitabine 2.8519294695
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.6914722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 5.0915687265 16977796
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 4.5717184923
MESH:D055728 Primary Myelofibrosis decitabine 5.1517616702
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.2120887781
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.5717136230 15046698 15846301
MESH:D011471 Prostatic Neoplasms Estradiol 2.5716740699
MESH:D011471 Prostatic Neoplasms Genistein 2.5715256057 16925846 15378649
MESH:D012208 Rhabdomyosarcoma decitabine 4.7519155313
MESH:D013088 Spermatocele Diethylstilbestrol 5.2316709447 16002989
MESH:D013274 Stomach Neoplasms marker/mechanism 16367923
MESH:D013274 Stomach Neoplasms decitabine 2.1019037991
MESH:D013964 Thyroid Neoplasms decitabine 3.5717967635
MESH:D013978 Tibial Fractures Estradiol 5.2119048282
MESH:D001749 Urinary Bladder Neoplasms decitabine 5.6917616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 5.6916712894 16452187 17306315
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 4.3416175088
MESH:D014591 Uterine Diseases Diethylstilbestrol 5.6914652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 4.4515809267 16690809
MESH:D014604 Uveal Neoplasms decitabine 5.4317785578
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.8516513791 16002989
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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