AutismKB 2.0

Annotation Detail for ST3GAL5


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Basic Information Top
Gene Symbol:ST3GAL5 ( SIAT9,SIATGM3S,ST3GalV )
Gene Full Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 5
Band: 2p11.2
Quick LinksEntrez ID:8869; OMIM: 604402; Uniprot ID:SIAT9_HUMAN; ENSEMBL ID: ENSG00000115525; HGNC ID: 10872
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00604Glycosphingolipid biosynthesis - ganglio series
hsa01100Metabolic pathways
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
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Desease Name
Amish infantile epilepsy syndrome
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of ST3GAL5 mRNAdecreases expression 19933214
D000082 Acetaminophen Acetaminophen affects the expression of ST3GAL5 mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of ST3GAL5 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ST3GAL5 mRNAaffects expression 16483693
D002087 Butyrates Butyrates results in increased expression of ST3GAL5 mRNAincreases expression 15541394
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of ST3GAL5 mRNAaffects expression 17484886
D016572 Cyclosporine Cyclosporine results in decreased expression of ST3GAL5 mRNAdecreases expression 20106945
D004281 Docosahexaenoic Acids Docosahexaenoic Acids results in increased expression of ST3GAL5 mRNAincreases expression 19805517
D004281 Docosahexaenoic Acids PPARD protein promotes the reaction [Docosahexaenoic Acids results in increased expression of ST3GAL5 mRNA]increases expression|increases reaction 19805517
D004317 Doxorubicin ST3GAL5 protein results in decreased susceptibility to Doxorubicindecreases response to substance 16571667
D005047 Etoposide ST3GAL5 protein results in decreased susceptibility to Etoposidedecreases response to substance 16571667
D005230 Fatty Acids, Nonesterified Fatty Acids, Nonesterified promotes the reaction [PPARD protein binds to ST3GAL5 enhancer]affects binding|increases reaction 19805517
D005679 G(M3) Ganglioside ST3GAL5 protein results in increased chemical synthesis of G(M3) Gangliosideincreases chemical synthesis 16571667
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased expression of ST3GAL5 mRNAincreases expression 17681415
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of ST3GAL5 mRNA]affects reaction|decreases expression 19482888
D010634 Phenobarbital Phenobarbital results in decreased expression of ST3GAL5 mRNAdecreases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of ST3GAL5 mRNAincreases expression 19270015
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ST3GAL5 mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of ST3GAL5 mRNAincreases expression 18445702
18301758
D013311 Streptozocin Streptozocin results in increased expression of ST3GAL5 mRNAincreases expression 16684804
D013311 Streptozocin vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of ST3GAL5 mRNA]decreases reaction|increases expression 16684804
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of ST3GAL5 mRNAdecreases expression 19933214
D014635 Valproic Acid Valproic Acid results in increased expression of ST3GAL5 mRNAincreases expression 19101580
C034028 vanadyl sulfate vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of ST3GAL5 mRNA]decreases reaction|increases expression 16684804
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 13.856195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 13.8515322242 14514962 11752688
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 13.858875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.8619490988
MESH:D000138 Acidosis Ammonium Chloride 3.5018287403
MESH:D055371 Acute Lung Injury pirinixic acid 3.0518653653
MESH:D000230 Adenocarcinoma Doxorubicin 2.5517418594
MESH:D018248 Adenoma, Liver Cell Phenobarbital 16.9417620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.9416434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.9416835633
MESH:D000419 Albuminuria Doxorubicin 4.4821441931
MESH:D000550 Amblyopia Valproic Acid 5.1817688650
OMIM:609056 AMISH INFANTILE EPILEPSY SYNDROME marker/mechanism
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8911748828
MESH:D000799 Angioedema Acetaminophen 3.7910982225
MESH:D001008 Anxiety Disorders Valproic Acid 3.5217497229
MESH:D001321 Autistic Disorder Acetaminophen 2.2518445737
MESH:D001321 Autistic Disorder Docosahexaenoic Acids 2.2518582451
MESH:D001321 Autistic Disorder Valproic Acid 2.2517507914 19232924 18316065 19460635 17157402 15238991 18775368 20603192 18396377 18940202 18558336 18177632 17688650 18985861 16609825
MESH:D001714 Bipolar Disorder Valproic Acid 3.0417594078 20046352
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.5619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.5612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 7.8815746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 7.888888407
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 11.9714601052
MESH:D019046 Bone Marrow Neoplasms Etoposide 11.9714601052
MESH:D001932 Brain Neoplasms Doxorubicin 3.7517150277
MESH:D001943 Breast Neoplasms Doxorubicin 1.9916096432 16322301 15136595 15994142 15939500 15567936 18234424 15993339 15668708 16826403 16115903 17426702 18628466 18695136 11325840 18382427 19526202 16935488 17369602 15692762 17983394 16264153 15634643 16595493
MESH:D001943 Breast Neoplasms Etoposide 1.9916322251
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9920435547
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.7216011737 16097048 18705752 16192424 3786805 15673190 16050911 16227642 10355542 15721981 15700767 16124888
MESH:D002276 Carcinoid Tumor Doxorubicin 12.5116051944
MESH:D002276 Carcinoid Tumor Streptozocin 12.5116051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7416835633
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 8.763084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 8.7612907637 12619106 21507988
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 8.7618788625
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 8.7616234567 16023760 18059187 17876044
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 8.766705139 1701930 20007298 17173139 20935162
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 3.131485588 16201981
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 2.626189445
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3316120746 18850075 18670907
MESH:D009202 Cardiomyopathies Doxorubicin 3.4818627295 17519947 16278810 17007740 16651473 17308081 16612575 15505089 15811867 16364871 17974986 17329180 16242529 17131338 17382496 15476868 15792986 16109756 16731534 16455267 17928571 17924179 16269455 16952015 17351982
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.9216243910 17334414
MESH:D002386 Cataract Acetaminophen 2.5410977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.4812371664
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.194080065
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.6820734317
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1016835633
MESH:D002779 Cholestasis Cyclosporine 7.5919486331
MESH:D002779 Cholestasis pirinixic acid 7.5919176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.088697196 15340226 16354765 15668235 12621046
MESH:D003110 Colonic Neoplasms Butyrates 3.0715936596
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.1418259882 18802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0017141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4520055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Valproic Acid 2.458888407 17688650 16575769
MESH:D003550 Cystic Fibrosis Docosahexaenoic Acids 4.6119747007
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3918249437
MESH:D003920 Diabetes Mellitus Streptozocin 4.6716285004
MESH:D003921 Diabetes Mellitus, Experimental Streptozocin 8.8712083368 2177838 19586609 12644472 1374869 6379147 18715473 19960420 15831366 16684804 15862027 19298542 12446591 7637645 18603373 17442507 8740154 16286809 15298345 17874149 11260395 11055810 12093613 19496084
MESH:D003921 Diabetes Mellitus, Experimental vanadyl sulfate 8.8716684804
MESH:D003922 Diabetes Mellitus, Type 1 Streptozocin 3.6118603373
MESH:D003924 Diabetes Mellitus, Type 2 Streptozocin 4.6019586609 19647726
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.6017107852
MESH:D058065 Diabetic Cardiomyopathies Streptozocin 5.6616025228
MESH:D003928 Diabetic Nephropathies Streptozocin 4.6119960420 19682444
MESH:D003930 Diabetic Retinopathy Streptozocin 5.3617662242
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.8114986274 17906064 19085960 15619225 17562736 12705907 11421492 16781746 16227642 12392966 11461765 14725611 16177239 12540782 19164858 14550746 18071297 19739265 16081117 2444490 15968718 19923254 12594235 10915739 17522070 19420014 16109766 11739529 19370779 10663392 11834606 11743745 19416960 18713872 16393943 11529661 12958197 10774834 16485898 12153990 11287661
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 11.8121278145 11566570 7179309 15998439 2869522 3786805 7440962 16177239 10915739 3732212 7120509 15968718 6884620 15027814 4309450 6623471 16227642 10092053 9327722 17522070 19336974 19085960
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 11.8117416283
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.8120420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 11.8119641884 1733752
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0419426721
MESH:D004362 Drug Toxicity Doxorubicin 7.9418602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.9411462148
MESH:D004421 Dystonia Phenobarbital 10.221851702
MESH:D004421 Dystonia Valproic Acid 10.221851702
MESH:D004487 Edema perfluorooctanoic acid 11.1117259670 12083418
MESH:D004487 Edema pirinixic acid 11.1112083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 11.1111000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8515322242 16714409 18230668
MESH:D016889 Endometrial Neoplasms Doxorubicin 3.4117359293
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.969294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.1018037988
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 10.583659116
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 10.5817275665 3659116
MESH:D004828 Epilepsies, Partial Phenobarbital 9.793922381 11558140
MESH:D004828 Epilepsies, Partial Valproic Acid 9.7916628512 3922381
MESH:D004827 Epilepsy Phenobarbital 6.5520417680
MESH:D004827 Epilepsy Valproic Acid 6.5518234410 20417680
MESH:D004832 Epilepsy, Absence Phenobarbital 8.676401628
MESH:D004832 Epilepsy, Absence Valproic Acid 8.676254150 7562514 6426943
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 11.097750514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 11.097750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 10.283659116
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 10.283659116
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9611564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 18.2516045604 17595544 12795759 19224547 12631006 16239168 15959796 61145
MESH:D005234 Fatty Liver Cyclosporine 18.2519224547
MESH:D005234 Fatty Liver pirinixic acid 18.2520131406 19236843
MESH:D005234 Fatty Liver Valproic Acid 18.2514986274 19224547
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3911858732
MESH:D005315 Fetal Diseases Valproic Acid 4.8316575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.078888407 18558336
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.5319069698
MESH:D005355 Fibrosis Carbon Tetrachloride 14.3518705752
MESH:D005355 Fibrosis Cyclosporine 14.3512168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.3520067830
MESH:D005756 Gastritis Acetaminophen 3.6216983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.168708960
MESH:D005909 Glioblastoma Doxorubicin 3.3117150277
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5410696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 3.4815692506
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3011294989 10048152
MESH:D006331 Heart Diseases Doxorubicin 7.9616330681 16495754 14766674 16244371 16879835 16144979 17888722 17875725 12587719 16707910 18674790 16244372 18006777
MESH:D006331 Heart Diseases Streptozocin 7.9612093613
MESH:D006333 Heart Failure Doxorubicin 6.9117481944
MESH:D006333 Heart Failure pirinixic acid 6.9120558911
MESH:D006394 Hemangiosarcoma Doxorubicin 3.8415692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3615720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2711000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.5319110552 19900420
MESH:D006529 Hepatomegaly perfluorooctanoic acid 20.183609246
MESH:D006529 Hepatomegaly Phenobarbital 20.1816109766
MESH:D006529 Hepatomegaly pirinixic acid 20.1819176532 16221962 18467677 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 20.1815340226 16120746 12621046
MESH:D006561 Herpes Simplex Etoposide 4.5010809021
MESH:D006689 Hodgkin Disease Doxorubicin 7.5518501091 17606976 15147373
MESH:D006689 Hodgkin Disease Etoposide 7.5517606976 16200630 15147373 18180244 16135485
MESH:D006849 Hydrocephalus Valproic Acid 4.8117688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.998697196 15340226 16959395 18606429 16354765
MESH:D006930 Hyperalgesia Acetaminophen 7.6816870215
MESH:D006930 Hyperalgesia perfluorooctanoic acid 7.6812083418
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.4716899240
MESH:D006943 Hyperglycemia pirinixic acid 3.1220558911
MESH:D006973 Hypertension Cyclosporine 4.8610903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.8618670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.0215338365
MESH:D007249 Inflammation perfluorooctanoic acid 5.0312083418
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 5.0312878042 12200463
MESH:D007333 Insulin Resistance pirinixic acid 2.5916306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2716580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3915604871
MESH:D007674 Kidney Diseases Acetaminophen 14.1812587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 14.188314463 10903974 18776723
MESH:D007674 Kidney Diseases Doxorubicin 14.1815699352 16775033 15369732
MESH:D007674 Kidney Diseases Streptozocin 14.1812093613
MESH:D007676 Kidney Failure, Chronic Doxorubicin 4.0916707910
MESH:D007680 Kidney Neoplasms Cyclosporine 2.6812371664
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.1016085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Docosahexaenoic Acids 4.9417077332
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1416294345 17596541
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 5.178812269
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.5111903743 16239168 16943688 17334410 11408273 17157831 21278145 16221502 17174718
MESH:D008103 Liver Cirrhosis Phenobarbital 6.5121047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.8714620537 16027843 12958196 15876570 15925388 16015684 18156304 18395095 17708605 18420326 15362042 17976157 17698563 17565644 17805973 18705752 15996030 14748882 18412020 14716496 15338365 18277467 10355542 18166357 12389079 11481614 18395914 17823541 12741479 17640975 18376398 15650968 18279442 17944888 13678700 12609069 15818738 16116963 17766677 15057751 17761835 15052691 18429990 18418968 15370692 16033810 14512876 18263696 12586293 16011737 16192424 18317297 16248980 15893842 18187930 15959796 15931870 14724832 18472094 14716833 18251166 18481824 15673190 16097048 18205269 12445421 16136751 17525996 17714472 12667390 18210741 20821823 18339082 12666154 17721639 18472332 15730626 17900296 12546737 17869086 12632512 17481882 17631135 15123356 18054572 12649538 18006644 17922224 12898905 12632514 17557913 16638106 12445418
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 4.8716439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.8715474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.8712878042
MESH:D008107 Liver Diseases Acetaminophen 9.3012969438 19014921 16611625 11587558 12587719 19784758 16610002 19460945
MESH:D008107 Liver Diseases Carbon Tetrachloride 9.3017285989 16964402 15720792 16246199 15830285
MESH:D008107 Liver Diseases Docosahexaenoic Acids 9.3017056761
MESH:D008107 Liver Diseases Phenobarbital 9.3019363144
MESH:D017093 Liver Failure Carbon Tetrachloride 4.1015123358
MESH:D017114 Liver Failure, Acute Acetaminophen 9.2117185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 9.2116899240 14706259
MESH:D008113 Liver Neoplasms Aflatoxin B1 17.6715890375 9163691 2125692 18177683
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 17.6719294768
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 17.6718709148 14757943
MESH:D008113 Liver Neoplasms Phenobarbital 17.6719073162 19812893 8742319 19482888 15975961 21047994
MESH:D008113 Liver Neoplasms pirinixic acid 17.6720007298 15890375 16377806
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.6716984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 18.218603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 18.2112014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 18.2117085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 18.2118308698 6150874 17172636 2563599 1399818
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 18.2112151625
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.2117228818
MESH:D008175 Lung Neoplasms Aflatoxin B1 3.4014755239
MESH:D008175 Lung Neoplasms Doxorubicin 3.406189445 17418594
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.4011884234 19555203
MESH:D008223 Lymphoma Doxorubicin 7.7516098063
MESH:D008223 Lymphoma Etoposide 7.7512556972 12854902
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.7317654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.5015621674
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 2.9915458769
MESH:D008545 Melanoma Doxorubicin 2.2816827129
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5019513568
MESH:D008654 Mesothelioma Doxorubicin 3.0317638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7316801185
MESH:D008881 Migraine Disorders Valproic Acid 3.1418765137 18803445
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.4415792986
MESH:D052016 Mucositis Doxorubicin 4.7317415656
MESH:D009135 Muscular Diseases pirinixic acid 3.4416239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.968888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.1217596541
MESH:D009203 Myocardial Infarction Doxorubicin 5.6219429709 15857846
MESH:D009203 Myocardial Infarction pirinixic acid 5.6219151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9612213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8916411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.4117484760
MESH:D009362 Neoplasm Metastasis Doxorubicin 2.9318259882
MESH:D009369 Neoplasms pirinixic acid 1.9217405874
MESH:D009401 Nephrosis Doxorubicin 4.7016899518 16636307
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3917954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 9.1019348381 18481113
MESH:D009404 Nephrotic Syndrome Doxorubicin 9.1016889571 15640375
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.1514600291
MESH:D009436 Neural Tube Defects Valproic Acid 3.0816359493 8888407
MESH:D009447 Neuroblastoma Doxorubicin 3.2315555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.8118514411
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.899802331
MESH:D009765 Obesity pirinixic acid 1.8020558911
MESH:D010018 Osteomalacia Phenobarbital 4.3017016548
MESH:D012516 Osteosarcoma Doxorubicin 4.0615930896
MESH:D010146 Pain Acetaminophen 2.3416870215
MESH:D010190 Pancreatic Neoplasms Etoposide 5.4919003803
MESH:D010190 Pancreatic Neoplasms Phenobarbital 5.4916965848
MESH:D010195 Pancreatitis Fatty Acids, Nonesterified 5.4318983441
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1912520081
MESH:D003557 Phyllodes Tumor Doxorubicin 5.1017983394
MESH:D010997 Pleural Neoplasms Doxorubicin 5.1017638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4918163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.7812371664
MESH:D011230 Precancerous Conditions Phenobarbital 8.782563599
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 15.9617132714
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 15.9611399792 11118676 11222880 11896295
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 15.9620603192
MESH:D011471 Prostatic Neoplasms Doxorubicin 3.6918437689 15897917 16888761 16868541 16729912 15749863
MESH:D011471 Prostatic Neoplasms Etoposide 3.6917172428
MESH:D019310 Pseudolymphoma Phenobarbital 12.0012752131
MESH:D019310 Pseudolymphoma Valproic Acid 12.0012752131 11422049
MESH:D011565 Psoriasis Cyclosporine 2.2116882103
MESH:D051437 Renal Insufficiency Doxorubicin 4.1617922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.3519058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7718990726
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.1119155313
MESH:D012509 Sarcoma Doxorubicin 3.9317203757 16767912 17710206 15625365 15675481 18313854
MESH:D012512 Sarcoma, Ewing's Doxorubicin 10.3416326096 14601052
MESH:D012512 Sarcoma, Ewing's Etoposide 10.3414601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.7317846226
MESH:D012559 Schizophrenia Valproic Acid 2.0615737665 19110320
MESH:D012640 Seizures Phenobarbital 5.853137016 4039156 11442880 16876388
MESH:D012640 Seizures Valproic Acid 5.851511512 14763951 17978042 16876388 3137016 15475178 11738929 11044598
MESH:D003294 Seizures, Febrile Phenobarbital 4.766407741
MESH:D012878 Skin Neoplasms Doxorubicin 5.5815692506
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.5816192470
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.5017203757 15625365 16767912
MESH:D016135 Spinal Dysraphism Valproic Acid 3.7319490988
MESH:D013226 Status Epilepticus Valproic Acid 4.4912833885
MESH:D013274 Stomach Neoplasms Docosahexaenoic Acids 3.0619015929
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8512697716
MESH:D013964 Thyroid Neoplasms Butyrates 11.8717967635
MESH:D013964 Thyroid Neoplasms Doxorubicin 11.8717909728 16010429
MESH:D013964 Thyroid Neoplasms Phenobarbital 11.871399818
MESH:D014178 Translocation, Genetic Valproic Acid 5.1817262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.463119515
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 2.7417653716
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.588888407
MESH:D014581 Urticaria Acetaminophen 2.9110982225
MESH:D014605 Uveitis Cyclosporine 3.931336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5412125929
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.1617678736 16364871 17638931 17334414
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1915886252
MESH:D014985 Xerophthalmia Cyclosporine 4.3917120751
Pathway ID Pathway Name
KEGG:00604 Glycosphingolipid biosynthesis - ganglio series
KEGG:01100 Metabolic pathways
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA35773
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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