AutismKB 2.0

Annotation Detail for CDC123


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Basic Information Top
Gene Symbol:CDC123 ( C10orf7,D123,FLJ13863 )
Gene Full Name: cell division cycle 123 homolog (S. cerevisiae)
Band: 10p14-p13
Quick LinksEntrez ID:8872; OMIM: NA; Uniprot ID:CD123_HUMAN; ENSEMBL ID: ENSG00000151465; HGNC ID: 16827
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
METABOLIC
type 2 diabetes
diabetes, type 2
Desease Name
Type 2 diabetes
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of CDC123 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of CDC123 mRNAaffects expression 17562736
C000188 alachlor alachlor results in increased expression of CDC123 mRNAincreases expression 12419858
C040534 alpha-hexachlorocyclohexane alpha-hexachlorocyclohexane results in increased expression of CDC123 mRNAincreases expression 16940010
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CDC123 mRNAaffects expression 16483693
D005419 Flavonoids Flavonoids results in decreased expression of CDC123 mRNAdecreases expression 18035473
C059514 resveratrol resveratrol results in decreased expression of CDC123 mRNAdecreases expression 12002526
C010327 salinomycin salinomycin results in decreased expression of CDC123 mRNAdecreases expression 19682730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.9018287403
MESH:D058186 Acute Kidney Injury resveratrol 4.0916538975
MESH:D000236 Adenoma resveratrol 3.4415688382
MESH:D000382 Agricultural Workers' Diseases alachlor 4.9911874814 14769641
MESH:D000544 Alzheimer Disease resveratrol 2.6116183991 16162502
MESH:D000799 Angioedema Acetaminophen 4.2210982225
MESH:D001169 Arthritis, Experimental resveratrol 3.6417115116
MESH:D050197 Atherosclerosis resveratrol 3.4016873680 17967414
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D002545 Brain Ischemia resveratrol 4.6217600658
MESH:D001943 Breast Neoplasms resveratrol 2.7217651959 16393696 17534123
MESH:D001943 Breast Neoplasms salinomycin 2.7219682730
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 4.7616705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.763084413
MESH:D006528 Carcinoma, Hepatocellular resveratrol 4.7619321006 16227395
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.9316675471
MESH:D002294 Carcinoma, Squamous Cell resveratrol 2.7716227395
MESH:D002318 Cardiovascular Diseases resveratrol 3.6315458977
MESH:D002386 Cataract Acetaminophen 2.7110977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 2.936135515
MESH:D003092 Colitis resveratrol 4.4316474422
MESH:D003110 Colonic Neoplasms resveratrol 2.4916338953
MESH:D015179 Colorectal Neoplasms resveratrol 2.2216550006
MESH:D003327 Coronary Disease resveratrol 3.8916507316
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.3218551238
MESH:D017449 Dermatitis, Allergic Contact alachlor 4.498428444
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.9716873680
MESH:D003928 Diabetic Nephropathies resveratrol 4.1816286809
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 3.9118551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.9119739265 14725611 19420014 16227642 11743745 16781746 18713872 18071297 11529661 11461765 19923254 19416960 10663392 14986274 12153990 15968718 12594235 17522070 11739529 11421492 19164858 12705907 12540782 11834606 17906064 16393943 15619225 10774834 14550746 16485898 2444490 19085960 10915739 12958197 11287661 16177239 16109766 16081117 12392966 17562736 19370779
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.4719426721
MESH:D004487 Edema resveratrol 3.608985016
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 4.3117872969
MESH:D020345 Enterocolitis, Necrotizing resveratrol 5.1617923197
MESH:D005756 Gastritis Acetaminophen 4.0516983495
MESH:D006561 Herpes Simplex resveratrol 4.5216876885
MESH:D006930 Hyperalgesia Acetaminophen 2.8916870215
MESH:D006937 Hypercholesterolemia resveratrol 4.2517188708
MESH:D006949 Hyperlipidemias resveratrol 4.2916873680
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.5317488730
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.9517600658
MESH:D007248 Infertility, Male alachlor 4.2912948887 17049205 16466525
MESH:D007249 Inflammation Flavonoids 5.7317296493
MESH:D007249 Inflammation resveratrol 5.7316366677
MESH:D007251 Influenza, Human resveratrol 4.9216624496
MESH:D007674 Kidney Diseases Acetaminophen 2.3215629191 12587719
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.1816705839
MESH:D007938 Leukemia alachlor 4.1214769641
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.7216087638
MESH:D008107 Liver Diseases Acetaminophen 1.6719014921 12587719 12969438 19784758 19460945 11587558 16611625 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.4616871587 17185352
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 4.997678174
MESH:D008113 Liver Neoplasms resveratrol 4.9919321006 19812893 20405173 19073162
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.682876784 6135515 2876786
MESH:D016393 Lymphoma, B-Cell resveratrol 4.5617088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 4.0714749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.5815688416
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 7.088985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental salinomycin 7.0819682730
MESH:D008545 Melanoma resveratrol 2.3917992120
MESH:D008546 Melanoma, Experimental Acetaminophen 3.8719513568
MESH:D008659 Metabolic Diseases resveratrol 4.6217112576
MESH:D009101 Multiple Myeloma alachlor 8.4214769641
MESH:D009101 Multiple Myeloma resveratrol 8.4216267019 16490592 17164350 17935668 14749477 17049120
MESH:D009134 Muscular Atrophy, Spinal resveratrol 5.2117962980
MESH:D009203 Myocardial Infarction resveratrol 3.1116317513 17188708 17015251 16525036 16456233 17125593
MESH:D017202 Myocardial Ischemia resveratrol 4.2017015251 17125593
MESH:D009205 Myocarditis resveratrol 5.1017322642
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.207678174 18551238
MESH:D009374 Neoplasms, Experimental resveratrol 4.318985016
MESH:D019636 Neurodegenerative Diseases Acetaminophen 9.0418514411
MESH:D019636 Neurodegenerative Diseases resveratrol 9.0417652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.6617929310
MESH:D009669 Nose Neoplasms alachlor 5.1611127290 16698726 15580706 14563481 16178123
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.6616049721
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.5217513867
MESH:D010146 Pain Acetaminophen 2.5916870215
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 4.5216679765
MESH:D011471 Prostatic Neoplasms resveratrol 3.5917804756 17675339 17636462 16731767 17718901 15767336
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.9616325855
MESH:D015427 Reperfusion Injury resveratrol 3.3717520802 17058453 16314181 16317513 15827377
MESH:D012135 Respiratory Sounds alachlor 5.2511874814
MESH:D012640 Seizures 2,6-dinitrotoluene 2.6918551238
MESH:D012878 Skin Neoplasms resveratrol 3.138985016 15837718
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.7116321402
MESH:D013964 Thyroid Neoplasms alachlor 4.458812207
MESH:D014062 Tongue Neoplasms resveratrol 4.4416227395
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.3716049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.6610091137
MESH:D014581 Urticaria Acetaminophen 3.2410982225
MESH:D002583 Uterine Cervical Neoplasms resveratrol 4.3317473185
MESH:D014594 Uterine Neoplasms resveratrol 4.4217044934
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.6117488730
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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