AutismKB 2.0

Annotation Detail for VNN1


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Basic Information Top
Gene Symbol:VNN1 ( HDLCQ8,MGC116930,MGC116931,MGC116932,MGC116933,Tiff66 )
Gene Full Name: vanin 1
Band: 6q23.2
Quick LinksEntrez ID:8876; OMIM: 603570; Uniprot ID:VNN1_HUMAN; ENSEMBL ID: ENSG00000112299; HGNC ID: 12705
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00770Pantothenate and CoA biosynthesis
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2091Hypertension
1882Malaria
No data
No data
Desease Name
High density lipoprotein cholesterol level QTL 8
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of VNN1 mRNAincreases expression 19933214
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of VNN1 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of VNN1 mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of VNN1 mRNAdecreases expression 18648102
D000638 Amiodarone Amiodarone affects the expression of VNN1 mRNAaffects expression 19483382
C006632 arsenic trioxide arsenic trioxide results in decreased expression of VNN1 mRNAdecreases expression 15761015
D001553 Benzbromarone Benzbromarone affects the expression of VNN1 mRNAaffects expression 19483382
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of VNN1 mRNAaffects cotreatment|increases expression 18164116
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of VNN1 mRNAincreases expression 20106945
D002994 Clofibrate PPARA protein affects the reaction [Clofibrate results in increased expression of VNN1 mRNA]affects reaction|increases expression 17585979
D002994 Clofibrate Clofibrate affects the expression of VNN1 mRNAaffects expression 19483382
D003314 Corn Oil Corn Oil affects the expression of VNN1 mRNAaffects expression 16360708
D016572 Cyclosporine Cyclosporine results in decreased expression of VNN1 mRNAdecreases expression 20106945
D004041 Dietary Fats Dietary Fats results in decreased expression of VNN1 mRNAdecreases expression 18042831
D004041 Dietary Fats Dietary Fats results in increased expression of VNN1 mRNAincreases expression 15238619
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of VNN1 mRNAaffects cotreatment|increases expression 18164116
D004054 Diethylstilbestrol Diethylstilbestrol results in decreased expression of VNN1 mRNAdecreases expression 15171707
D005001 Ethionine Ethionine affects the expression of VNN1 mRNAaffects expression 19483382
D011345 Fenofibrate Fenofibrate results in increased expression of VNN1 mRNAincreases expression 11798191
D009853 Omeprazole Omeprazole affects the expression of VNN1 mRNAaffects expression 19483382
C041786 palm oil palm oil results in decreased expression of VNN1 mRNAdecreases expression 18042831
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of VNN1 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of VNN1 mRNAincreases expression 19482888
D010795 Phthalic Acids Phthalic Acids results in decreased expression of VNN1 mRNAdecreases expression 15728792
C006253 pirinixic acid pirinixic acid results in increased expression of VNN1 mRNAincreases expression 17426115
20059764
18301758
11798191
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of VNN1 mRNA]increases expression|increases reaction 20059764
C006253 pirinixic acid pirinixic acid affects the expression of VNN1 mRNAaffects expression 19483382
D011441 Propylthiouracil Propylthiouracil affects the expression of VNN1 mRNAaffects expression 19483382
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of VNN1 mRNAincreases expression 19933214
D013853 Thioacetamide Thioacetamide affects the expression of VNN1 mRNAaffects expression 19483382
D014241 Trichloroethylene Trichloroethylene results in increased expression of VNN1 mRNAincreases expression 17905399
D015032 Zinc Zinc affects the expression of VNN1 mRNAaffects expression 16979875
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 7.536195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.5311752688 14514962 15322242
MESH:D000169 Acrodermatitis Zinc 5.1717190629 17202136 16889938
MESH:D055371 Acute Lung Injury pirinixic acid 2.9118653653
MESH:D000230 Adenocarcinoma arsenic trioxide 4.1519825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.1520127859 20464547
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 14.903712494
MESH:D000236 Adenoma Benzo(a)pyrene 14.906695378
MESH:D000236 Adenoma beta-Naphthoflavone 14.9019389873
MESH:D000236 Adenoma Diethylnitrosamine 14.906695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 22.9717620307 19052882 18056438 19061943 17162532 16434500
MESH:D018248 Adenoma, Liver Cell Phenobarbital 22.9717620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 22.9716434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 22.9716835633
MESH:D000544 Alzheimer Disease Zinc 2.7116325427 16410023 16580781 17119284
MESH:D000686 Amyloidosis Diethylstilbestrol 4.2615469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7511748828
MESH:D000755 Anemia, Sickle Cell Zinc 4.6816916123
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.8519183758
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.6020041841 18218290 18057881
MESH:D001161 Arteriosclerosis Dietary Fats 3.6615238619
MESH:D001249 Asthma Zinc 2.8917085522
MESH:D001281 Atrial Fibrillation Amiodarone 3.7318651412 19698954
MESH:D001289 Attention Deficit Disorder with Hyperactivity Phthalic Acids 4.2120106747
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.791440618 11289319
MESH:D001778 Blood Coagulation Disorders Amiodarone 61.8319483382
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 61.8316206674
MESH:D001778 Blood Coagulation Disorders Benzbromarone 61.8319483382
MESH:D001778 Blood Coagulation Disorders Clofibrate 61.8319483382
MESH:D001778 Blood Coagulation Disorders Ethionine 61.8319483382
MESH:D001778 Blood Coagulation Disorders Omeprazole 61.8319483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 61.8319483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 61.8319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 61.8312125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 61.8319483382
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6215746008
MESH:D001930 Brain Injuries Zinc 4.4717109824
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.8517474063 20146248
MESH:D001943 Breast Neoplasms Dietary Fats 2.8520435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.8517474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 2.8517129689 15324884
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.8520435547
MESH:D001943 Breast Neoplasms Trichloroethylene 2.8515986119
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1211589617
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6216835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 19.1616705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 19.1616705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 19.163581430 7296757
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 19.1611135700 16217749 15073043 15553829 14691202
MESH:D006528 Carcinoma, Hepatocellular Benzbromarone 19.161701930
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 19.1617173139 20935162 18665156 19701751 20214788 3581430 10672840 19394651 17761372 19519916 18494052 19052882 20101231 19822196 10737359 20524982 18056438 20007298 16698587 3084413 20514400 19335982 17055752 16779866 11831363 18210153 19208518 18785209 16540662 20084675 16935385 17428255 18978308 16807293 18506893 18393292 19539802 19107877 17978847 20512989 21159647 19171122 18691550 20432363 18971187 19383236 16569478 17138121 20727157 16328049 18788625 17162532 19919837 16502159 16681979 16878318 19418558 16830150 16288022
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 19.1616924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 19.166705139 1701930 20007298 17173139 20935162
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 19.1617997003
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.6419014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.577296757
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9212490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.5620419170
MESH:D002294 Carcinoma, Squamous Cell Zinc 4.5616543248
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2418670907 18850075 16120746
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.8219225199 15710769
MESH:D002318 Cardiovascular Diseases Zinc 3.5016936243
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.8518974383
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 19.456135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 19.457505956
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 19.451399818
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 19.4512371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 19.452727394 21159647 17174075 7505956
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.034080065
MESH:D002637 Chest Pain Omeprazole 4.8815447763
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 15.0119052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 15.0116835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 15.0118291259
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 12.419022650 19486331
MESH:D002779 Cholestasis Cyclosporine 12.4119486331
MESH:D002779 Cholestasis pirinixic acid 12.4119176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0112621046 15340226 15668235 8697196 16354765
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.8714669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.9712609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.7010525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.7020055451 15322242 10048152
MESH:D019465 Craniofacial Abnormalities Zinc 3.7019302082
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.3412952375 16002989
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.1418551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.1418551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.8815213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.592524372 8156756 18759878 11906362 14531868 12868966 8970840 11298694
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3218249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.283621924 2952479
MESH:D003920 Diabetes Mellitus Zinc 4.0116479319
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.0320387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.0317107852
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 21.0318551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 21.0321346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 21.0311289319 6679447 9022650 16192314 18289764 7440962 18648102 1440618 6482804 8291058 9653073 9328219 18692083
MESH:D056486 Drug-Induced Liver Injury Amiodarone 21.0315265979 18218290
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 21.0319107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 21.0320420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 21.0312963478
MESH:D056486 Drug-Induced Liver Injury Trichloroethylene 21.037120509
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.5911462148
MESH:D004381 Duodenal Ulcer Omeprazole 4.1117151854 15991576 16613094 21218061
MESH:D050171 Dyslipidemias Clofibrate 13.7116707586
MESH:D050171 Dyslipidemias Dietary Fats 13.7118367378
MESH:D050171 Dyslipidemias Fenofibrate 13.7116707586
MESH:D004421 Dystonia Phenobarbital 3.791851702
MESH:D004487 Edema pirinixic acid 5.8712083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.8711000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.6718230668 15322242 16714409
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.4616402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 7.4615700306 16804899
MESH:D016889 Endometrial Neoplasms Fenofibrate 7.4616569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.8210568697 9294722
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.883659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.643922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.7720417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.356401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.037750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.793659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.8916302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 9.913581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 9.9112903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 9.9116530937
MESH:D004938 Esophageal Neoplasms Zinc 9.9116543248
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8411564622
MESH:D005218 Fat Necrosis Thioacetamide 5.4916456712
MESH:D005234 Fatty Liver Amiodarone 33.8214986274
MESH:D005234 Fatty Liver arsenic trioxide 33.8215073043
MESH:D005234 Fatty Liver Clofibrate 33.8219224547
MESH:D005234 Fatty Liver Cyclosporine 33.8219224547
MESH:D005234 Fatty Liver Dietary Fats 33.8218296743 19004024 17967931 19551842
MESH:D005234 Fatty Liver Diethylnitrosamine 33.8221071580 20387270
MESH:D005234 Fatty Liver pirinixic acid 33.8219236843 20131406
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.5215751030 16611131 16002989 16534752 16513791
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2311858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.796705139
MESH:D005355 Fibrosis Cyclosporine 13.4212168785 12639820
MESH:D005355 Fibrosis Dietary Fats 13.4218296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 13.4220067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.0416904648
MESH:D005756 Gastritis Zinc 4.5717241300
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.7216452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.998708960
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.827505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3610696789
MESH:D006130 Growth Disorders Zinc 3.8217217573
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.0520471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.0510048152 11294989
MESH:D006333 Heart Failure pirinixic acid 6.6920558911
MESH:D006333 Heart Failure Zinc 6.6917162251
MESH:D006335 Heart Injuries Zinc 5.5417074742
MESH:D016481 Helicobacter Infections Zinc 4.3217241300
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.1915720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1311000095
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.3718665440 17276928 15929193
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 8.726705139
MESH:D006505 Hepatitis Thioacetamide 8.7216456712
MESH:D006527 Hepatolenticular Degeneration Zinc 4.4717276780
MESH:D006529 Hepatomegaly Amiodarone 18.8315265979
MESH:D006529 Hepatomegaly Phenobarbital 18.8316109766
MESH:D006529 Hepatomegaly pirinixic acid 18.8316221962 19772884 18467677 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 18.8312621046 16120746 15340226
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.818697196 16354765 16959395 18606429 15340226
MESH:D006937 Hypercholesterolemia Amiodarone 8.489751232 8137927
MESH:D006937 Hypercholesterolemia Dietary Fats 8.4821332399
MESH:D006943 Hyperglycemia pirinixic acid 2.9920558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.4021332399
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 10.0915034207
MESH:D006965 Hyperplasia Diethylstilbestrol 10.0912960047 14722030
MESH:D006968 Hypersensitivity, Delayed Corn Oil 5.5811484837
MESH:D006973 Hypertension Cyclosporine 4.6610903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.6618670907 18850075
MESH:D007021 Hypospadias Diethylstilbestrol 4.3516002989
MESH:D007037 Hypothyroidism Amiodarone 10.8617991464 18020914
MESH:D007037 Hypothyroidism Propylthiouracil 10.868137927 18031379
MESH:D007246 Infertility Diethylstilbestrol 4.1415036965
MESH:D007249 Inflammation Dietary Fats 7.5920412841
MESH:D007249 Inflammation Diethylnitrosamine 7.5918785209
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 7.5912878042 12200463
MESH:D015212 Inflammatory Bowel Diseases therapeutic 17145956
MESH:D007333 Insulin Resistance Dietary Fats 6.7611836018 18457598
MESH:D007333 Insulin Resistance pirinixic acid 6.7616306350
MESH:D007511 Ischemia Zinc 4.4116584753
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.799022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1316580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2115604871
MESH:D007674 Kidney Diseases Cyclosporine 5.788314463 18776723 10903974
MESH:D007674 Kidney Diseases Zinc 5.7816960431
MESH:D007676 Kidney Failure, Chronic Zinc 4.2216518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 21.3716705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 21.3716705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 21.376582329
MESH:D007680 Kidney Neoplasms Cyclosporine 21.3712371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 21.3714681315 16762066 15003126
MESH:D007859 Learning Disorders Diethylstilbestrol 3.8417184923
MESH:D016773 Leishmaniasis, Cutaneous Omeprazole 3.9119248655
MESH:D007938 Leukemia arsenic trioxide 2.7215070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.5912560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.0816972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.2614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.5619077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1019850784 16968895 16467208 20471514 17050201
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.0712712474 15622746 15336539 17869043 12018890 17217047 11468182 12679006 9834237 16966277 19035177 16330433 16112521 16823087 16331271 17649720 15748426 15213294 19642359 19075265 17107899 19225113 17712046 16891316 11161223
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.1316882451
MESH:D052439 Lipid Metabolism Disorders marker/mechanism
MESH:D008064 Lipidoses Amiodarone 3.3515342952 17567588
MESH:D008103 Liver Cirrhosis Dietary Fats 10.3118296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 10.3118665156 19638242 18522880 18407596 20032147
MESH:D008103 Liver Cirrhosis Phenobarbital 10.3121047994
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.0615034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Fenofibrate 4.7615474484
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.7615474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.7612878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 4.7618295389 17355460 16098781 12085344 14739098 16511523 12679928 15158331 17050028 17292413 11481614 15095483 17127702 15716488 11172339 15362042 15288473 12891558 15316131 18615449 15334695 18031379 18395095 16343077 18416461 11682029 18032466 10677585 17629604 15474484 15075984 12175628 12531686 16126171 15078482 16489207 15288472 18606216 18263696 18380797 15465738 16097051 18458672 12557150 16248980
MESH:D008107 Liver Diseases Diethylnitrosamine 6.2717034775
MESH:D008107 Liver Diseases Phenobarbital 6.2719363144
MESH:D008107 Liver Diseases Thioacetamide 6.2718374380 16337175 15158337
MESH:D017114 Liver Failure, Acute Thioacetamide 4.1112479984 17276928 15633222 15313186
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 32.617678174
MESH:D008113 Liver Neoplasms arsenic trioxide 32.6114682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 32.6121137059 20195826
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 32.6119389873 21295105
MESH:D008113 Liver Neoplasms Diethylnitrosamine 32.6116942905 18977376 18754104 20101389 20492335 19812893 20405173 18648771 19073162 15885732 21047994 2862719 19427195 19850985 18644402 19254457 19426721 19690152 9163691 15175105 10737359 2422723 19833225 12112319 19256749 21278145 21071580 19642983 20583210 18978307 19499222 20452335 19294768 19090486 19996281 20434301 19638242 20137499 21167192 19551842 12771043 19255062 20501860 20118626
MESH:D008113 Liver Neoplasms Diethylstilbestrol 32.6115890375 16712894
MESH:D008113 Liver Neoplasms Fenofibrate 32.6118978307
MESH:D008113 Liver Neoplasms Phenobarbital 32.6121047994 8742319 19073162 19812893 15975961 19482888
MESH:D008113 Liver Neoplasms pirinixic acid 32.6120007298 15890375 16377806
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 32.6116984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 35.752876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 35.753712494 6587162 598648 1399818
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 35.7520377131
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 35.7518164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 35.7517854601 3124819 18282651 18164116 18544905 18093689 19539802 17942915 17174075 19126423 18775883 18253720 19004024 19519916 16842330 9362446 2563599 19009564 18308698 16267830 21159647 18079962
MESH:D008114 Liver Neoplasms, Experimental Fenofibrate 35.7518775883 18253720
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 35.7517172636 6150874 1399818 18308698 2563599
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 35.7512151625
MESH:D008114 Liver Neoplasms, Experimental Trichloroethylene 35.757955063
MESH:D008133 Long QT Syndrome Amiodarone 7.6217391786 11989578 15350150
MESH:D008133 Long QT Syndrome arsenic trioxide 7.6215213294
MESH:D008171 Lung Diseases Amiodarone 3.2212587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 4.2518516814
MESH:D008175 Lung Neoplasms arsenic trioxide 4.5911798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 4.5917053015 20064080 20464547 20135361 18816296 18520028 18569708 20869020 6695378
MESH:D008175 Lung Neoplasms Diethylnitrosamine 4.5920970405 6695378 21163286 20512841
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.5919555203 11884234
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.9215166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.3115700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.2816002989
MESH:D008325 Mammary Neoplasms, Experimental Zinc 3.1612773700
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.5616801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.0216381670
MESH:D009101 Multiple Myeloma arsenic trioxide 2.9515949261 14977855 19549372 19417148 11468182
MESH:D009135 Muscular Diseases pirinixic acid 3.2816239165
MESH:D009181 Mycoses Amiodarone 4.6712754197 17974566
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.4418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.0116105982 16882451
MESH:D009203 Myocardial Infarction pirinixic acid 2.0519151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8412213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.7716411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.2517484760
MESH:D009336 Necrosis 2,4-dinitrotoluene 9.5818551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 9.5818551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.7416624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 5.403581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.409029167 3581430
MESH:D009369 Neoplasms Benzo(a)pyrene 10.9811141357
MESH:D009369 Neoplasms Diethylstilbestrol 10.9815313581
MESH:D009369 Neoplasms pirinixic acid 10.9817405874
MESH:D009369 Neoplasms Trichloroethylene 10.9811911487
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.0918481113 19348381
MESH:D009421 Nervous System Malformations Diethylstilbestrol 8.9211399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.9214600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 6.766679447
MESH:D009436 Neural Tube Defects arsenic trioxide 6.7610525206
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.1620387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.8920387270
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 4.719802331
MESH:D009765 Obesity Dietary Fats 4.2419632207 20518802 18674790 11836018 21332399 20132043 18457598 17217161 16723640
MESH:D009765 Obesity pirinixic acid 4.2420558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 13.9212819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 13.9216049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 13.926482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.793988306
MESH:D010018 Osteomalacia Phenobarbital 4.1317016548
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.3419769630 16624393 12452020
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 8.1315580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.1316540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 8.1316965848
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.267296757
MESH:D010235 Paraganglioma arsenic trioxide 3.9519927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0212520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.246228378
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.9414722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.4515687265 16977796
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3418163543
MESH:D011230 Precancerous Conditions Corn Oil 20.3514668109
MESH:D011230 Precancerous Conditions Cyclosporine 20.3512371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 20.352563599
MESH:D011230 Precancerous Conditions Phenobarbital 20.352563599
MESH:D011225 Pre-Eclampsia Zinc 4.0017114810
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 8.8017184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.8011118676 11399792 11896295 11222880
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.1519131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.1517292933
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.1517136230 15046698 15846301
MESH:D011471 Prostatic Neoplasms Zinc 2.1516606632 16700911 16517595 12429649
MESH:D019310 Pseudolymphoma Phenobarbital 4.2612752131
MESH:D011565 Psoriasis Cyclosporine 2.1516882103
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.7711597910 12490602 12832656
MESH:D015427 Reperfusion Injury pirinixic acid 2.2819058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6218990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 8.453692021
MESH:D012162 Retinal Degeneration Zinc 8.4516584753
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.7416646077
MESH:D012640 Seizures 2,4-dinitrotoluene 8.9218551238
MESH:D012640 Seizures 2,6-dinitrotoluene 8.9218551238
MESH:D012640 Seizures Phenobarbital 8.9211442880 16876388 3137016 4039156
MESH:D003294 Seizures, Febrile Phenobarbital 4.596407741
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.8518724381
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.1210029692 19755658
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.1216192470
MESH:D013088 Spermatocele Diethylstilbestrol 4.4816709447 16002989
MESH:D013272 Stomach Diseases Omeprazole 4.3818545984
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.2117007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.2120155912 2093021
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.2118456281
MESH:D013276 Stomach Ulcer Amiodarone 6.9018087811
MESH:D013276 Stomach Ulcer Omeprazole 6.9010750652 15991576 16755016 18237397 11906479 17977527
MESH:D013610 Tachycardia Amiodarone 4.0711238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 3.9719225199
MESH:D013959 Thyroid Diseases Amiodarone 11.2819731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 11.2812697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 20.656582329 7505956 1399818 6587162 3712494
MESH:D013964 Thyroid Neoplasms arsenic trioxide 20.6519014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 20.657505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 20.651399818
MESH:D013964 Thyroid Neoplasms Propylthiouracil 20.6515710170
MESH:D013971 Thyrotoxicosis Amiodarone 4.6319584973 18020914
MESH:D014062 Tongue Neoplasms Zinc 4.2016543248
MESH:D016171 Torsades de Pointes Amiodarone 9.5017467628 11989578
MESH:D016171 Torsades de Pointes arsenic trioxide 9.5015213294
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 18.7116049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 18.7116049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 18.718074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 18.7111780464 20435036 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 18.7117053015
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 18.7117306315 16452187 16712894
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.2210091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.2210091137
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 3.8416175088
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.9414652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 3.8515809267 16690809
MESH:D014605 Uveitis Cyclosporine 3.751336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.2116002989 16513791
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3612125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0215886252
MESH:D015430 Weight Gain Dietary Fats 3.5516723640
MESH:D014985 Xerophthalmia Cyclosporine 4.2117120751
Pathway ID Pathway Name
KEGG:00770 Pantothenate and CoA biosynthesis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA37321
    • No data
    Releated disease ID Related disease Name
    PA445174Osteoarthritis
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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